The Oncosearch | Oncotarget

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Pratima Nangia-Makker, Malathy P.V. Shekhar, Victor Hogan, Vitaly Balan, Avraham Raz

Published Mar 9, 2022 · Vol. 13, No. 1 · pp. 534-550

Keywords: myosin II, MYH9, dNTP, deoxyribose-5-phosphate, DNA synthesis

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity Research Paper

Daniel Menendez, Jay R. Anand, Carri C. Murphy, Whitney J. Bell, Jiaqi Fu, Nadia Slepushkina, Eugen Buehler, Scott E. Martin, Madhu Lal-Nag, John L. Nitiss, Michael A. Resnick

Published Feb 4, 2022 · Vol. 13, No. 1 · pp. 332-346

Keywords: tumor suppressor, siRNA screen, synthetic lethality, ICE assay, Top2 covalent complexes

Correction: HRD1 suppresses the growth and metastasis of breast cancer cells by promoting IGF-1R degradation Correction

Yue-Mei Xu, Hong-Jiang Wang, Fang Chen, Wan-Hua Guo, Yan-Yang Wang, Hang-Yu Li, Jin-Hai Tang, Ying Ding, Ya-Chen Shen, Min Li, Wen-Ying Xuan, Lin-Hui Liu, Jia Wang, Xue-Rong Wang, Ze-Jun Gao, Xiu-Bin Liang, Dong-Ming Su

Published Jan 25, 2022

Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study Research Paper

Connor Willis, Hillevi Bauer, Trang H. Au, Jyothi Menon, Sudhir Unni, Dao Tran, Zachary Rivers, Wallace Akerley, Matthew B. Schabath, Firas Badin, Ashley Sekhon, Malini Patel, Bing Xia, Beth Gustafson, John L. Villano, John-Michael Thomas, Solomon J. Lubinga, Michael A. Cantrell, Diana Brixner, David Stenehjem

Published Jan 7, 2022 · Vol. 13, No. 1 · pp. 257-270

Keywords: lung neoplasma, tumor biomarkers, immunotherapy

The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells Research Paper

Austin McDermott, KyoungHyun Kim, Susan Kasper, Shuk-Mei Ho, Yuet-Kin Leung

Published Dec 23, 2021 · Vol. 13, No. 1 · pp. 46-60

Keywords: GPR30, castration resistant, promoter, GPER1 spliced variants, transcription start site

Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype Research Paper

Elham Khosrowabadi, Tomasz Wenta, Salla Keskitalo, Aki Manninen, Sakari Kellokumpu

Published Dec 22, 2021 · Vol. 13, No. 1 · pp. 73-89

Keywords: cancer, invasion, glycosylation, glycocode, terminal GalNAc, Helix Pomatia agglutinin (HPA)

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Krishma Tailor, Joseph Paul, Somiranjan Ghosh, Namita Kumari, Bernard Kwabi-Addo

Published Dec 15, 2021 · Vol. 12, No. 26 · pp. 2489-2499

Keywords: RASAL2, Ras-protooncogene, prostate cancer, TNFα signal, DNA methylation

Correction: A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer Correction

Ben Liu, Xining Zhang, Fengju Song, Qun Liu, Hongji Dai, Hong Zheng, Ping Cui, Lina Zhang, Wei Zhang, Kexin Chen

Published Dec 15, 2021

The clinician’s perspective on the 21-gene assay in early breast cancer Review

Francesco Cognetti, Giuseppe Naso

Published Dec 1, 2021 · Vol. 12, No. 26 · pp. 2514-2530

Keywords: Oncotype DX test, recurrence score results, multigene assays, genomic tests, personalized medicine

Correction: Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer Correction

Igor Vujic, Martina Sanlorenzo, Christian Posch, Rosaura Esteve-Puig, Adam J. Yen, Andrew Kwong, Aaron Tsumura, Ryan Murphy, Klemens Rappersberger, Susana Ortiz-Urda

Published Oct 29, 2021

Correction: Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance Correction

Benny Zhitomirsky, Yehuda G. Assaraf

Published Oct 28, 2021 · Vol. 13, No. 1 · pp. 585-586

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Lara H. El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B. Dull, Deborah F. Wilsker, Melinda G. Hollingshead, Michelle Gottholm-Ahalt, Sergio Y. Alcoser, Michael E. Mullendore, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher, Annamaria Rapisarda

Published Sep 28, 2021 · Vol. 12, No. 21 · pp. 2114-2130

Keywords: TMZ, MMR, ATR, HR, REV3L

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Issam Makhoul, Saddam Mohammed Ibrahim, Muhammad Abu-Rmaileh, Fariba Jousheghany, Eric R. Siegel, Lora J. Rogers, John J. Lee, Sergio Pina-Oviedo, Ginell R. Post, J. Thaddeus Beck, Thomas Kieber-Emmons, Behjatolah Monzavi-Karbassi

Published Sep 16, 2021 · Vol. 12, No. 22 · pp. 2252-2265

Keywords: cancer vaccine, peptide mimotopes, combination therapy, breast cancer

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Shuai Zhao, Wafik S. El-Deiry

Published Sep 15, 2021 · Vol. 12, No. 20 · pp. 1970-1979

Keywords: Smurf2, CDK4/6 inhibition, HIF1alpha, hypoxia, cancer therapy

Safety and initial efficacy of ablative radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma Research Paper

Ricardo Paz-Fumagalli, Jacob Core, Carlos Padula, Seyed Montazeri, John McKinney, Gregory Frey, Zlatko Devcic, Andrew Lewis, Charles Ritchie, Kabir Mody, Sunil Krishnan, Beau Toskich

Published Aug 21, 2021 · Vol. 12, No. 20 · pp. 2075-2088

Keywords: Yttrium-90, radioembolization, cholangiocarcinoma, angiography, radiation dosimetry

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Zhiguang Xiao, Bianca Sperl, Silvia Gärtner, Tatiana Nedelko, Elvira Stacher-Priehse, Axel Ullrich, Pjotr G. Knyazev

Published Aug 14, 2021 · Vol. 12, No. 17 · pp. 1734-1735

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Mario Scarpa, Shivani Kapoor, Eric S. Tvedte, Kshama A. Doshi, Ying S. Zou, Prerna Singh, Jonelle K. Lee, Aditi Chatterjee, Moaath K. Mustafa Ali, Robin E. Bromley, Julie C. Dunning Hotopp, Feyruz V. Rassool, Maria R. Baer

Published Aug 2, 2021 · Vol. 12, No. 18 · pp. 1763-1779

Keywords: FLT3 internal tandem duplication, Pim kinase, alternative non-homologous end-joining DNA repair, genomic instability, topoisomerase 2 inhibitors

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Subarna Ghosh, Priyanka Dey Talukdar, Abhinandan Bhattacharjee, Sarbani Giri, Nitai Pada Bhattacharyya, Urmi Chatterji

Published Jul 2, 2021 · Vol. 12, No. 15 · pp. 1520-1539

Keywords: arecoline, tight junction, head and neck cancer, lncRNA-NEAT1, JunD

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Rodney J. Scott, Anurag Mehta, Gabriel S. Macedo, Pavel S. Borisov, Ravindran Kanesvaran, Wafaa El Metnawy

Published Jun 22, 2021 · Vol. 12, No. 16 · pp. 1600-1614

Keywords: metastatic castration-resistant prostate cancer, homologous recombination repair, next generation sequencing, genetic testing

Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target Research Paper

Natsumi Hayashi, Akitaka Yamasaki, Shiho Ueda, Shogo Okazaki, Yoshiya Ohno, Toshiyuki Tanaka, Yuichi Endo, Yoshihisa Tomioka, Kazue Masuko, Takashi Masuko, Reiko Sugiura

Published May 29, 2021 · Vol. 12, No. 13 · pp. 1256-1270

Keywords: CD98, LAT1, monoclonal antibody, NIH/3T3, oncogenicity

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MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity Research Paper

Correction: HRD1 suppresses the growth and metastasis of breast cancer cells by promoting IGF-1R degradation Correction

Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study Research Paper

The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells Research Paper

Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype Research Paper

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Correction: A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer Correction

The clinician’s perspective on the 21-gene assay in early breast cancer Review

Correction: Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer Correction

Correction: Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance Correction

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Safety and initial efficacy of ablative radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma Research Paper

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity Research Paper

Correction: HRD1 suppresses the growth and metastasis of breast cancer cells by promoting IGF-1R degradation Correction

Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study Research Paper

The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells Research Paper

Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype Research Paper

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Correction: A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer Correction

The clinician’s perspective on the 21-gene assay in early breast cancer Review

Correction: Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer Correction

Correction: Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance Correction

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide Priority Research Paper

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Safety and initial efficacy of ablative radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma Research Paper

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper