The Oncosearch | Oncotarget

Ras functional proximity proteomics establishes mTORC2 as new direct ras effector Research Perspective

Joanna R. Kovalski, Ronald L. Shanderson, Paul A. Khavari

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5126-5135

Keywords: Ras, BioID, proteomics, CRISPR, mTORC2

Mechanism of internalization of MDA-7/IL-24 protein and its cognate receptors following ligand-receptor docking Research Paper

Anjan K. Pradhan, Praveen Bhoopathi, Sarmistha Talukdar, Swadesh K. Das, Luni Emdad, Devanand Sarkar, Andrei I. Ivanov, Paul B. Fisher

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5103-5117

Keywords: MDA-7/Interleukin-24, Interleukin receptor, recombinant protein

Association of baseline inflammatory biomarkers with cancer mortality in the REGARDS cohort Research Paper

Tomi Akinyemiju, Justin X. Moore, Daniel Tefera Dibaba, Maria Pisu, Michael Goodman, Virginia J. Howard, Monika Safford, Susan C. Gilchrist, Mary Cushman, LeAnn Long, Suzanne E. Judd

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4857-4867

Keywords: inflammatory biomarkers, racial disparities, cancer mortality, obesity

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma Research Paper

Huda H. Al-Khalaf, Abdelilah Aboussekhra

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4868-4879

Keywords: osteosarcoma, AUF1, VEGF-A, HIF-1α, angiogenesis

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Elisabet Frick, Thorkell Gudjonsson, Jorunn Eyfjord, Jon Jonasson, Laufey Tryggvadóttir, Olafur Stefansson, Stefan Sigurdsson

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4664-4678

Keywords: breast cancer, microRNA-190b, DNA methylation, prognosis, estrogen receptor

Impact on survival of tobacco smoking for cases with oropharyngeal squamous cell carcinoma and known human papillomavirus and p16-status: a multicenter retrospective study Research Paper

Christian Grønhøj, Jakob Schmidt Jensen, Steffen Wagner, Christian Dehlendorff, Jeppe Friborg, Elo Andersen, Claus Wittekindt, Nora Würdemann, Shachi Jenny Sharma, Stefan Gattenlöhner, Jens Peter Klussmann, Christian von Buchwald

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4655-4663

Keywords: oropharyngeal cancer, human papillomavirus, smoking, survival

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

Laila Babar, Juliann E. Kosovec, Vida Jahangiri, Nobel Chowdhury, Ping Zheng, Ashten N. Omstead, Madison S. Salvitti, Matthew A. Smith, Ajay Goel, Ronan J. Kelly, Blair A. Jobe, Ali H. Zaidi

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4546-4555

Keywords: esophageal adenocarcinoma, LAG3, IDO1, CXCL9, TIM3

Identification of ZYG11A as a candidate IGF1-dependent proto-oncogene in endometrial cancer Research Paper

Laris Achlaug, Rive Sarfstein, Karthik Nagaraj, Lena Lapkina-Gendler, Ilan Bruchim, Manisha Dixit, Zvi Laron, Shoshana Yakar, Haim Werner

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4437-4448

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor, ZYG11A, p53, endometrial cancer

Comparative RNA-seq analysis reveals dys-regulation of major canonical pathways in ERG-inducible LNCaP cell progression model of prostate cancer Research Paper

Parameet Kumar, Joyeeta Chakraborty, Gauthaman Sukumar, Clifton Dalgard, Raghunath Chatterjee, Roopa Biswas

Published Jul 2, 2019 · Vol. 10, No. 42 · pp. 4290-4306

Keywords: RNAseq, prostate cancer, LNCaP cells, ERG, mRNA

AGR2, a unique tumor-associated antigen, is a promising candidate for antibody targeting Research Paper

Alvin Y. Liu, Adelle D. Kanan, Tomasz P. Radon, Siama Shah, Mark E. Weeks, Julie M. Foster, Jane K. Sosabowski, Laurent Dumartin, Tatjana Crnogorac-Jurcevic

Published Jul 2, 2019 · Vol. 10, No. 42 · pp. 4276-4289

Keywords: pancreatic cancer, eAGR2, chimeric antibody, prostate cancer, tumor localization

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

Osamu Ichiyanagi, Hiromi Ito, Sei Naito, Takanobu Kabasawa, Hidenori Kanno, Takafumi Narisawa, Masaki Ushijima, Yuta Kurota, Michinobu Ozawa, Toshihiko Sakurai, Hayato Nishida, Tomoyuki Kato, Mitsunori Yamakawa, Norihiko Tsuchiya

Published Jun 18, 2019 · Vol. 10, No. 40 · pp. 4053-4068

Keywords: renal cell carcinoma, phospho-eIF4E (p-eIF4E), MNK (MAPK-interacting kinase), recurrence-free, epithelial−mesenchymal transition

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes Research Paper

Nadin D. Exner, Jaime Alberto Campos Valenzuela, Khalil Abou-El-Ardat, Hrvoje Miletic, Peter C. Huszthy, Petra M. Radehaus, Evelin Schröck, Rolf Bjerkvig, Lars Kaderali, Barbara Klink, Janice M. Nigro

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3641-3653

Keywords: exome sequencing, IDH1, oligodendroglioma, SNV, xenograft

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells Research Paper

Kathryn Clarke, Christine Young, Fabio Liberante, Mary-Frances McMullin, Alexander Thompson, Ken Mills

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3462-3471

Keywords: HDAC inhibitor, epigenetic, transcriptional regulation, myelodysplastic syndrome (MDS)

Correction: Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress Correction

Yu-Chin Lin, Meng-Hsuan Wu, Tzu-Tang Wei, Yun-Chieh Lin, Wen-Chih Huang, Liang-Yu Huang, Yi-Ting Lin, Ching-Chow Chen

Published May 24, 2019 · Vol. 10, No. 37 · pp. 3577-3578

Prevalence of cardiovascular risk factors and diseases in patients with multiple myeloma undergoing autologous peripheral blood stem cell transplantation Research Paper

Deborah Backs, Ilknur Saglam, Claudia Löffler, Sandra Ihne, Caroline Morbach, Susanne Brenner, Christiane Angermann, Georg Ertl, Stefan Frantz, Stefan Störk, Stefan Knop, Gülmisal Güder

Published May 7, 2019 · Vol. 10, No. 34 · pp. 3154-3165

Keywords: cardiovascular risk factors, cardiovascular diseases, multiple myeloma, arterial hypertension, echocardiography

The glutamate release inhibitor riluzole increases DNA damage and enhances cytotoxicity in human glioma cells, in vitro and in vivo Research Paper

Atif J. Khan, Stephanie LaCava, Monal Mehta, Devora Schiff, Aditya Thandoni, Sachin Jhawar, Shabbar Danish, Bruce G. Haffty, Suzie Chen

Published Apr 19, 2019 · Vol. 10, No. 29 · pp. 2824-2834

Keywords: glutamate, glioma, riluzole, radiation therapy

Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours Research Paper

Liliana D. Ordonez, Trevor Hay, Robert McEwen, Urszula M. Polanska, Adina Hughes, Oona Delpuech, Elaine Cadogan, Steve Powell, Jonathan Dry, Giusy Tornillo, Lucy Silcock, Elisabetta Leo, Mark J. O’Connor, Alan R. Clarke, Matthew J. Smalley

Published Apr 5, 2019 · Vol. 10, No. 27 · pp. 2586-2606

Keywords: PARP inhibitors, olaparib, Brca2, EMT, P-gps

Plasma RANKL levels are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers Research Paper

Tasnim Zaman, Ping Sun, Steven A. Narod, Leonardo Salmena, Joanne Kotsopoulos

Published Mar 29, 2019 · Vol. 10, No. 25 · pp. 2475-2483

Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-Mutant mammary tumours Research Paper

Liliana D. Ordonez, Trevor Hay, Robert McEwen, Urszula M. Polanska, Adina Hughes, Oona Delpuech, Elaine Cadogan, Steve Powell, Jonathan Dry, Giusy Tornillo, Lucy Silcock, Elisabetta Leo, Mark J. O’Connor, Alan R. Clarke, Matthew J. Smalley

Published Mar 27, 2019

Keywords: PARP inhibitors, olaparib, Brca2, EMT, P-gps

Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-Mutant mammary tumours Research Paper

Liliana D. Ordonez, Trevor Hay, Robert McEwen, Urszula M. Polanska, Adina Hughes, Oona Delpuech, Elaine Cadogan, Steve Powell, Jonathan Dry, Giusy Tornillo, Lucy Silcock, Elisabetta Leo, Mark J. O’Connor, Alan R. Clarke, Matthew J. Smalley

Published Mar 27, 2019

Keywords: PARP inhibitors, olaparib, Brca2, EMT, P-gps

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Ras functional proximity proteomics establishes mTORC2 as new direct ras effector Research Perspective

Mechanism of internalization of MDA-7/IL-24 protein and its cognate receptors following ligand-receptor docking Research Paper

Association of baseline inflammatory biomarkers with cancer mortality in the REGARDS cohort Research Paper

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma Research Paper

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Impact on survival of tobacco smoking for cases with oropharyngeal squamous cell carcinoma and known human papillomavirus and p16-status: a multicenter retrospective study Research Paper

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

Identification of ZYG11A as a candidate IGF1-dependent proto-oncogene in endometrial cancer Research Paper

Comparative RNA-seq analysis reveals dys-regulation of major canonical pathways in ERG-inducible LNCaP cell progression model of prostate cancer Research Paper

AGR2, a unique tumor-associated antigen, is a promising candidate for antibody targeting Research Paper

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes Research Paper

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells Research Paper

Correction: Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress Correction

Prevalence of cardiovascular risk factors and diseases in patients with multiple myeloma undergoing autologous peripheral blood stem cell transplantation Research Paper

The glutamate release inhibitor riluzole increases DNA damage and enhances cytotoxicity in human glioma cells, in vitro and in vivo Research Paper

Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours Research Paper

Plasma RANKL levels are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers Research Paper

Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-Mutant mammary tumours Research Paper

Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-Mutant mammary tumours Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Ras functional proximity proteomics establishes mTORC2 as new direct ras effector Research Perspective

Mechanism of internalization of MDA-7/IL-24 protein and its cognate receptors following ligand-receptor docking Research Paper

Association of baseline inflammatory biomarkers with cancer mortality in the REGARDS cohort Research Paper

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma Research Paper

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Impact on survival of tobacco smoking for cases with oropharyngeal squamous cell carcinoma and known human papillomavirus and p16-status: a multicenter retrospective study Research Paper

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

Identification of ZYG11A as a candidate IGF1-dependent proto-oncogene in endometrial cancer Research Paper

Comparative RNA-seq analysis reveals dys-regulation of major canonical pathways in ERG-inducible LNCaP cell progression model of prostate cancer Research Paper

AGR2, a unique tumor-associated antigen, is a promising candidate for antibody targeting Research Paper

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes Research Paper

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells Research Paper

Correction: Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress Correction

Prevalence of cardiovascular risk factors and diseases in patients with multiple myeloma undergoing autologous peripheral blood stem cell transplantation Research Paper

The glutamate release inhibitor riluzole increases DNA damage and enhances cytotoxicity in human glioma cells, in vitro and in vivo Research Paper

Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours Research Paper

Plasma RANKL levels are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers Research Paper

Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-Mutant mammary tumours Research Paper

Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-Mutant mammary tumours Research Paper