The Oncosearch | Oncotarget

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Mathew Lozinski, Nikola A. Bowden, Moira C. Graves, Michael Fay, Bryan W. Day, Brett W. Stringer, Paul A. Tooney

Published Jan 5, 2024 · Vol. 15, No. 1 · pp. 1-18

Keywords: glioblastoma, DNA damage response, ataxia-telangiectasia and rad3-related protein, radiation therapy, temozolomide

Correction: HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide Correction

Alessandro Canella, Hector Cordero Nieves, Douglas W. Sborov, Luciano Cascione, Hanna S. Radomska, Emily Smith, Andrew Stiff, Jessica Consiglio, Enrico Caserta, Lara Rizzotto, Nicola Zanesi, Volinia Stefano, Balveen Kaur, Xiaokui Mo, John C. Byrd, Yvonne A. Efebera, Craig C. Hofmeister, Flavia Pichiorri

Published Sep 23, 2023 · Vol. 14, No. 1 · pp. 837-838

Targeting Ras with protein engineering Review

Atilio Tomazini, Julia M. Shifman

Published Jun 21, 2023 · Vol. 14, No. 1 · pp. 672-687

Keywords: Ras oncogene, anti-Ras therapeutics, Ras targeting, protein engineering, protein design

Deciphering the mechanisms of action of progesterone in breast cancer Research Perspective

Gaurav Chakravorty, Suhail Ahmad, Mukul S. Godbole, Sudeep Gupta, Rajendra A. Badwe, Amit Dutt

Published Jun 5, 2023 · Vol. 14, No. 1 · pp. 660-667

Keywords: breast cancer, progesterone, DSCAM-AS1, endocrine therapy

Retraction: The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma Retraction

Yi Xu, Kaiming Leng, Zhenglong Li, Fumin Zhang, Xiangyu Zhong, Pengcheng Kang, Xingming Jiang, Yunfu Cui

Published Apr 27, 2023 · Vol. 14, No. 1 · pp. 779-779

Importance of carbohydrate antigen (CA 19-9) and carcinoembrionic antigen (CEA) in the prognosis of patients with duodenal adenocarcinoma: a retrospective single-institution cohort study Research Paper

Ellery Altshuler, Raymond Richhart, William King, Mahmoud Aryan, Akash Mathavan, Akshay Mathavan, Keegan Hones, Daniel F. Leach III, Logan Pucci, Joshua Riklan, Pat Haley, Ilyas Sahin, Brian Ramnaraign, Sherise Rogers, Ibrahim Nassour, Steven Hughes, Thomas J. George, Jesus Fabregas

Published Apr 4, 2023 · Vol. 14, No. 1 · pp. 351-357

Keywords: duodenal adenocarcinoma, carbohydrate antigen, CA 19-9, carcinoembrionic antigen, CEA

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines Research Paper

Nada Tawfeeq, Jassy Mary S. Lazarte, Yonghao Jin, Matthew D. Gregory, Nazarius S. Lamango

Published Mar 15, 2023 · Vol. 14, No. 1 · pp. 243-257

Keywords: PCAIs, G-proteins, KRAS, RHOA, RAC1

Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels Research Paper

Christina Kuhn, Myriam Boeschen, Manuel Philip, Torsten Schöneberg, Doreen Thor, Susanne Horn

Published Dec 27, 2022 · Vol. 14, No. 1 · pp. 14-20

Keywords: neuroblastoma, drug sensitivity, drug resistance, drug repurposing, DLST

The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies Research Paper

Jyothi Puvula, Narendra Maddu, Nagajothi Gutam, Asha Parimal, Pongali B. Raghavendra

Published Dec 1, 2022 · Vol. 13, No. 1 · pp. 1323-1340

Keywords: allethrin, prallethrin, autophagy, apoptosis, Ccl2

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway Research Paper

Jen-Chieh Lee, Shu Liu, Yucheng Wang, You Liang, David M. Jablons

Published Oct 26, 2022 · Vol. 13, No. 1 · pp. 1217-1236

Keywords: AML, CDK8, kinase inhibitor, STAT pathway, xenograft

Genomic alterations predictive of poor clinical outcomes in pan-cancer Research Paper

Crystal S. Seldon, Karthik Meiyappan, Hannah Hoffman, Jimmy A. Guo, Neha Goel, William L. Hwang, Paul L. Nguyen, Brandon A. Mahal, Mohammed Alshalalfa

Published Sep 20, 2022 · Vol. 13, No. 1 · pp. 1069-1077

Keywords: genomic alterations, TP53, TCGA, poor prognosis

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy Research Paper

Daiki Ueno, Juan C. Vasquez, Amrita Sule, Jiayu Liang, Jinny van Doorn, Ranjini Sundaram, Sam Friedman, Randy Caliliw, Shinji Ohtake, Xun Bao, Jing Li, Huihui Ye, Karla Boyd, Rong Rong Huang, Jack Dodson, Paul Boutros, Ranjit S. Bindra, Brian Shuch

Published Sep 3, 2022 · Vol. 13, No. 1 · pp. 1054-1067

Keywords: FH, SDHB, renal cell carcinoma, PARP inhibitor, temozolomide

Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma Research Paper

Aayush Aayush, Saloni Darji, Deepika Dhawan, Alexander Enstrom, Meaghan M. Broman, Muhammad T. Idrees, Hristos Kaimakliotis, Timothy Ratliff, Deborah Knapp, David Thompson

Published Aug 27, 2022 · Vol. 13, No. 1 · pp. 1004-1016

Keywords: bladder cancer, elastin-like polypeptide, NIR imaging, epidermal growth factor receptor (EGFR), translational studies

A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling Priority Research Paper

Stephan J. Matissek, Mona Karbalivand, Weiguo Han, Ava Boutilier, Estefania Yzar-Garcia, Laura L. Kehoe, Devin Storm Gardner, Adam Hage, Krista Fleck, Vicki Jeffers, Ricardo Rajsbaum, Sherine F. Elsawa

Published Jul 29, 2022 · Vol. 13, No. 1 · pp. 944-959

Keywords: GLI3, inflammation, TLR

Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel cell carcinoma Research Paper

Sujatha Muralidharan, Thibault Kervarrec, Glen J. Weiss, Mahtab Samimi

Published Jul 20, 2022 · Vol. 13, No. 1 · pp. 960-967

Keywords: Merkel cell carcinoma, glypican-3, Merkel cell polyomavirus, outcome

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer Research Paper

Marina Baretti, Qingfeng Zhu, Wei Fu, Jeffrey Meyer, Hao Wang, Robert A. Anders, Nilofer S. Azad

Published Jul 6, 2022 · Vol. 13, No. 1 · pp. 907-917

Keywords: programmed death ligand 1, tumor-infiltrating lymphocytes, immune checkpoints, colorectal cancer, neoadjuvant chemoradiotherapy

CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells Research Paper

Julianne Huegel, Christine T. Dinh, Maria Martinelli, Olena Bracho, Rosa Rosario, Haley Hardin, Michael Estivill, Anthony Griswold, Sakir Gultekin, Xue-Zhong Liu, Cristina Fernandez-Valle

Published Jul 2, 2022 · Vol. 13, No. 1 · pp. 890-904

Keywords: fimepinostat, Schwann cell, vestibular schwanomma, merlin, nerve allograft

Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation Research Paper

Raquel Torres-Guzmán, Maria Patricia Ganado, Cecilia Mur, Carlos Marugan, Carmen Baquero, Yanzhu Yang, Yi Zeng, Huimin Bian, Jian Du, Alfonso de Dios, Oscar Puig, María José Lallena

Published Jun 22, 2022 · Vol. 13, No. 1 · pp. 864-875

Keywords: abemaciclib, breast cancer, cell lines, CDK4/6, continuous dosing

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

Travis P. Schrank, Andrew C. Prince, Tejas Sathe, Xiaowei Wang, Xinyi Liu, Damir T. Alzhanov, Barbara Burtness, Albert S. Baldwin, Wendell G. Yarbrough, Natalia Issaeva

Published May 7, 2022 · Vol. 13, No. 1 · pp. 707-722

Keywords: HPV, head and neck cancer, CYLD, TRAF3, NF-κB

Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study Research Paper

Carolina Sciortino, Valentina Viglialoro, Massimo Nucci, Mariam Grazia Polito, Enrico Cortesi, Alain Gelibter, Paola Gazzaniga, Chiara Nicolazzo, Marco Siringo, Salvatore Caponnetto

Published Apr 29, 2022 · Vol. 13, No. 1 · pp. 686-693

Keywords: NSCLC, immunotherapy, KRAS G12C mutation, liquid biopsy

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ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Correction: HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide Correction

Targeting Ras with protein engineering Review

Deciphering the mechanisms of action of progesterone in breast cancer Research Perspective

Retraction: The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma Retraction

Importance of carbohydrate antigen (CA 19-9) and carcinoembrionic antigen (CEA) in the prognosis of patients with duodenal adenocarcinoma: a retrospective single-institution cohort study Research Paper

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines Research Paper

Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels Research Paper

The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies Research Paper

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway Research Paper

Genomic alterations predictive of poor clinical outcomes in pan-cancer Research Paper

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy Research Paper

Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma Research Paper

A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling Priority Research Paper

Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel cell carcinoma Research Paper

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer Research Paper

CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells Research Paper

Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation Research Paper

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Correction: HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide Correction

Targeting Ras with protein engineering Review

Deciphering the mechanisms of action of progesterone in breast cancer Research Perspective

Retraction: The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma Retraction

Importance of carbohydrate antigen (CA 19-9) and carcinoembrionic antigen (CEA) in the prognosis of patients with duodenal adenocarcinoma: a retrospective single-institution cohort study Research Paper

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines Research Paper

Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels Research Paper

The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies Research Paper

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway Research Paper

Genomic alterations predictive of poor clinical outcomes in pan-cancer Research Paper

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy Research Paper

Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma Research Paper

A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling Priority Research Paper

Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel cell carcinoma Research Paper

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer Research Paper

CUDC907, a dual phosphoinositide-3 kinase/histone deacetylase inhibitor, promotes apoptosis of NF2 Schwannoma cells Research Paper

Continuous treatment with abemaciclib leads to sustained and efficient inhibition of breast cancer cell proliferation Research Paper

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study Research Paper