The Oncosearch | Oncotarget

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Zhi-Qiang Wang, Magdalena Bachvarova, Chantale Morin, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Dimcho Bachvarov

Published Jan 27, 2014 · Vol. 5, No. 2 · pp. 544-560

Keywords: GALNT3, epithelial ovarian cancer, DNA hypomethylation, progression-free survival, microarrays, mucin O-glycosylation

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

Marcella Salzano, Marta VÃ¡zquez-Cedeira, Marta Sanz-GarcÃa, Alberto Valbuena, Sandra Blanco, Isabel F. FernÃ¡ndez, Pedro A. Lazo

Published Jan 17, 2014 · Vol. 5, No. 7 · pp. 1770-1778

Keywords: Breast cancer, VRK1, Radiation, doxorubicin, chemotherapy, DNA damage, 53BP1

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth Research Paper

David Vindrieux, Guillaume Devailly, Arnaud Augert, Benjamin Le Calve, Mylene Ferrand, Pascal Pigny, Lea Payen, Gerard Lambeau, Michael Perrais, Sebastien Aubert, HÃ©lÃ¨ne Simonnet, Robert Dante, David Bernard

Published Jan 16, 2014 · Vol. 5, No. 4 · pp. 1004-1013

Keywords: VHL, MYC, HIF, PLA2R1, tumor suppressor

Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma Research Paper

Uwe Schirmer, Kai Doberstein, Anne-Kathleen Rupp, Niko P. Bretz, Daniela Wuttig, Helena Kiefel, Christian Breunig, Heidi Fiegl, Elisabeth MÃ¼ller-Holzner, Robert Zeillinger, Eva Schuster, Alain G. Zeimet, Holger SÃ¼ltmann, Peter Altevogt

Published Jan 12, 2014 · Vol. 5, No. 2 · pp. 462-472

Keywords: miR-34a, endometrial carcinoma, L1CAM, ovarian carcinoma

RB1 gene inactivation by chromothripsis in human retinoblastoma Research Paper

Justina McEvoy, Panduka Nagahawatte, David Finkelstein, Jennifer Richards-Yutz, Marcus Valentine, Jing Ma, Charles Mullighan, Guangchun Song, Xiang Chen, Matthew Wilson, Rachel Brennan, Stanely Pounds, Jared Becksfort, Robert Huether, Charles Lu, Robert S. Fulton, Lucinda L. Fulton, Xin Hong, David J. Dooling, Kerri Ochoa, Elaine R. Mardis, Richard K. Wilson, John Easton, Jinghui Zhang, James R. Downing, Arupa Ganguly, Michael A. Dyer

Published Jan 11, 2014 · Vol. 5, No. 2 · pp. 438-450

Keywords: chromothripsis, retinoblastoma, RB1, MYCN

Minor grove binding ligands disrupt PARP-1 activation pathways Research Paper

Kirill Kirsanov, Elena Kotova, Petr Makhov, Konstantin Golovine, Ekaterina A. Lesovaya, Vladimir M. Kolenko, Marianna G. Yakubovskaya, Alexei V. Tulin

Published Jan 3, 2014 · Vol. 5, No. 2 · pp. 428-437

Keywords: PARP-1, PARP-1 inhibitors, DNA-binding small molecules, poly(ADP-ribose)

Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites Research Paper

Catherine A. Vaughan, Swati P. Deb, Sumitra Deb, Brad Windle

Published Jan 2, 2014 · Vol. 5, No. 2 · pp. 417-427

Keywords: mutant p53, ChIP-Seq, ETS1, bi-directional promoter

Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma Research Paper

Catherine Gratas, Quentin SÃ©ry, Marion RabÃ©, Lisa Oliver, FranÃ§ois M. Vallette

Published Jan 1, 2014 · Vol. 5, No. 9 · pp. 2428-2435

Keywords: cell death, Bcl-2 family, glioma, temozolomide

Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway Research Paper

Bahityar Rahmutulla, Kazuyuki Matsushita, Mamoru Satoh, Masanori Seimiya, Sachio Tsuchida, Shuji Kubo, Hideaki Shimada, Masayuki Ohtsuka, Masaru Miyazaki, Fumio Nomura

Published Dec 21, 2013 · Vol. 5, No. 9 · pp. 2404-2417

Keywords: FBP interacting repressor (FIR), bleomycin, DNA damage, Ku86, c-Myc, P27Kip1

Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer. Research Paper

MarÃa JosÃ© Escamez, Francisco Garcia-Garcia, Gemma Tell-Marti, Angels Fabra, LucÃa MartÃnez-SantamarÃa, Celia Badenas, Paula Aguilera, Marta Pevida, JoaquÃn Dopazo, Marcela del RÃo, Susana Puig

Published Dec 16, 2013 · Vol. 5, No. 6 · pp. 1439-1451

Keywords: Familial Melanoma, CDKN2A, MC1R, gene expression, p16, mutations

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells Research Paper

Liliana H. Mochmann, Martin Neumann, Eva K. von Der Heide, Verena Nowak, Anja A. KÃ¼hl, Jutta Ortiz-Tanchez, Juliane Bock, Wolf K Hofmann, Claudia D Baldus

Published Dec 4, 2013 · Vol. 5, No. 2 · pp. 351-362

Keywords: ERG, ERK, EMT, Chemoresistance

Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system Research Paper

Sun-Hye Lee, Tae-Gyun Woo, Su-Jin Lee, Nam-Chul Ha, Bum-Joon Park

Published Dec 2, 2013 · Vol. 4, No. 12 · pp. 2523-2531

Keywords: p53 core domain, Oncogenic K-Ras, Caveolin-1, Drug delivery

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

Christine B. Ambrosone, Allyson C. Young, Lara E. Sucheston, Dan Wang, Li Yan, Song Liu, Li Tang, Qiang Hu, Jo L. Freudenheim, Peter G. Shields, Carl D. Morrison, Kitaw Demissie, Michael J. Higgins

Published Nov 29, 2013 · Vol. 5, No. 1 · pp. 237-248

Keywords: DNA methylation, breast cancer, disparities, estrogen receptor, African-American, genome-wide

Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth Research Paper

Jinyun Chen, Franklin Chung, Guizhi Yang, Minying Pu, Hui Gao, Wei Jiang, Hong Yin, Vladimir Capka, Shailaja Kasibhatla, Bryan Laffitte, Savina Jaeger, Raymond Pagliarini, Yaoyu Chen, Wenlai Zhou

Published Nov 26, 2013 · Vol. 4, No. 12 · pp. 2502-2511

Keywords: PHGDH, breast cancer cells, in vivo

Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis Research Paper

Akinori Morita, Shinya Ariyasu, Soichiro Ohya, Ippei Takahashi, Bing Wang, Kaoru Tanaka, Takatoshi Uchida, Haruna Okazaki, Kengo Hanaya, Atsushi Enomoto, Mitsuru Nenoi, Masahiko Ikekita, Shin Aoki, Yoshio Hosoi

Published Nov 24, 2013 · Vol. 4, No. 12 · pp. 2439-2450

Keywords: p53, zinc chelator, zinc binding site, radiation, apoptosis

Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-ÐºB target genes in human breast cancer Research Paper

Alba Dalmases, Irene Gonzalez-Navarrete, Silvia Menendez, Oriol ArpÃ, Josep Maria Coromines, Sonia Servitja, Ignasi Tusquets, Cristina Chamizo, RaÃºl RincÃ³n, LluÃs Espinosa, Anna Bigas, Pilar Eroles, Jessica Furriol, Anna Lluch, Ana Rovira, Joan Albanell, Federico Rojo

Published Nov 23, 2013 · Vol. 5, No. 1 · pp. 196-210

Keywords: breast cancer, chemoresistance, NF-ÐºB, p53, prognosis

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma Research Paper

Hsin-Pai Li, Chen-Ching Peng, I-Che Chung, Mei-Yuan Huang, Shao-Tung Huang, Chia-Chun Chen, Kai-Ping Chang, Cheng-Lung Hsu, Yu-Sun Chang

Published Nov 4, 2013 · Vol. 4, No. 11 · pp. 2154-2165

Keywords: HOXA2, DNA methylation, NPC, MMP9

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

John Wrangle, Wei Wang, Alexander Koch, Hariharan Easwaran, Helai P. Mohammad, Xiaoyu Pan, Frank Vendetti, Wim VanCriekinge, Tim DeMeyer, Zhengzong Du, Princy Parsana, Kristen Rodgers, Ray-Whay Yen, Cynthia A. Zahnow, Janis M. Taube, Julie R. Brahmer, Scott S. Tykodi, Keith Easton, Richard D. Carvajal, Peter A. Jones, Peter W. Laird, Daniel J. Weisenberger, Salina Tsai, Rosalyn A. Juergens, Suzanne L. Topalian, Charles M. Rudin, Malcolm V. Brock, Drew Pardoll, Stephen B. Baylin

Published Oct 25, 2013 · Vol. 4, No. 11 · pp. 2067-2079

Cytokine-induced â€˜bystanderâ€™ senescence in DDR and immuno-surveillance Editorial Materials

Zdenek Hodny, Sona Hubackova, Jiri Bartek

Published Oct 16, 2013 · Vol. 4, No. 10 · pp. 1552-1553

Keywords: senescence, cytokines, DNA damage response

Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma Research Paper

Yoshinari Shinsato, Tatsuhiko Furukawa, Shunji Yunoue, Hajime Yonezawa, Kentarou Minami, Yukihiko Nishizawa, Ryuji Ikeda, Kohichi Kawahara, Masatatsu Yamamoto, Hirofumi Hirano, Hiroshi Tokimura, Kazunori Arita

Published Oct 14, 2013 · Vol. 4, No. 12 · pp. 2261-2270

Keywords: temozolomide, MLH1, PMS2, MutL-alphaï€, resistance, recurrence, glioblastoma

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Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth Research Paper

Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma Research Paper

RB1 gene inactivation by chromothripsis in human retinoblastoma Research Paper

Minor grove binding ligands disrupt PARP-1 activation pathways Research Paper

Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites Research Paper

Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma Research Paper

Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway Research Paper

Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer. Research Paper

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells Research Paper

Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system Research Paper

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth Research Paper

Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis Research Paper

Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-ÐºB target genes in human breast cancer Research Paper

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma Research Paper

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

Cytokine-induced â€˜bystanderâ€™ senescence in DDR and immuno-surveillance Editorial Materials

Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth Research Paper

Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma Research Paper

RB1 gene inactivation by chromothripsis in human retinoblastoma Research Paper

Minor grove binding ligands disrupt PARP-1 activation pathways Research Paper

Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites Research Paper

Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma Research Paper

Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway Research Paper

Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer. Research Paper

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells Research Paper

Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system Research Paper

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth Research Paper

Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis Research Paper

Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-ÐºB target genes in human breast cancer Research Paper

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma Research Paper

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

Cytokine-induced â€˜bystanderâ€™ senescence in DDR and immuno-surveillance Editorial Materials

Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma Research Paper