The Oncosearch | Oncotarget

Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients Research Paper

Maria Serova, AnnemilaÃ¯ Tijeras-Raballand, CÃ©lia Dos Santos, Miguel Albuquerque, Valerie Paradis, Cindy Neuzillet, Karim A. Benhadji, Eric Raymond, Sandrine Faivre, Armand de Gramont

Published May 27, 2015 · Vol. 6, No. 25 · pp. 21614-21627

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells Research Paper

Rute Loureiro, Silvia MagalhÃ£es-Novais, Katia A. Mesquita, Ines Baldeiras, Isabel S. Sousa, Ludgero C. Tavares, Ines A. Barbosa, Paulo J. Oliveira, Ignacio Vega-Naredo

Published May 20, 2015 · Vol. 6, No. 19 · pp. 17081-17096

Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter Research Paper

Jian-Ge Qiu, Yao-Jun Zhang, Yong Li, Jin-Ming Zhao, Wen-Ji Zhang, Qi-Wei Jiang, Xiao-Long Mei, You-Qiu Xue, Wu-Ming Qin, Yang Yang, Di-Wei Zheng, Yao Chen, Meng-Ning Wei, Zhi Shi

Published Apr 14, 2015 · Vol. 6, No. 17 · pp. 15494-15509

Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer Research Paper

Jian Wang, Hui Wang, Aifen Liu, Changge Fang, Jianguo Hao, Zhenghui Wang

Published Apr 10, 2015 · Vol. 6, No. 23 · pp. 19456-19468

Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models Priority Research Paper

Giovanna Bianchi, Roberto Martella, Silvia Ravera, Cecilia Marini, Selene Capitanio, Annamaria Orengo, Laura Emionite, Chiara Lavarello, Adriana Amaro, Andrea Petretto, Ulrich Pfeffer, Gianmario Sambuceti, Vito Pistoia, Lizzia Raffaghello, Valter D. Longo

Published Mar 30, 2015 · Vol. 6, No. 14 · pp. 11806-11819

AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts Priority Research Paper

Joffrey Pelletier, DaniÃ¨le Roux, Benoit Viollet, Nathalie M. Mazure, Jacques PouyssÃ©gur

Published Mar 30, 2015 · Vol. 6, No. 14 · pp. 11833-11847

Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism Research Paper

Sandra Leisz, Kristin Schulz, Susanne Erb, Peter Oefner, Katja Dettmer, Dimitrios Mougiakakos, Ena Wang, Francesco M. Marincola, Franziska Stehle, Barbara Seliger

Published Mar 27, 2015 · Vol. 6, No. 13 · pp. 11395-11406

The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2 Research Paper

Nicolas Skrypek, Romain Vasseur, Audrey Vincent, BÃ©linda DuchÃªne, Isabelle Van Seuningen, Nicolas Jonckheere

Published Mar 26, 2015 · Vol. 6, No. 13 · pp. 10853-10867

A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging Research Paper

Marianne Schauer, Tina Kottek, Madeleine SchÃ¶nherr, Animesh Bhattacharya, Saleh M. Ibrahim, Misa Hirose, RÃ¼diger KÃ¶hling, Georg Fuellen, Ulf Schmitz, Manfred Kunz

Published Mar 24, 2015 · Vol. 6, No. 11 · pp. 8552-8566

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab Research Paper

Xinqun Li, Yang Lu, Haiquan Lu, Jingtao Luo, Yun Hong, Zhen Fan

Published Mar 20, 2015 · Vol. 6, No. 13 · pp. 11507-11518

Targeting AMPK for cancer prevention and treatment Review

Weidong Li, Shakir M. Saud, Matthew R. Young, Guohong Chen, Baojin Hua

Published Mar 20, 2015 · Vol. 6, No. 10 · pp. 7365-7378

RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer Research Paper

Chengcheng Guo, Chuncheng Hao, RuPing Shao, Bingliang Fang, Arlene M. Correa, Wayne L. Hofstetter, Jack A. Roth, Carmen Behrens, Neda Kalhor, Ignacio I. Wistuba, Stephen G. Swisher, Apar Pataer

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11114-11124

A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties Research Paper

Melissa R. Pitman, Jason A. Powell, Carl Coolen, Paul A.B. Moretti, Julia R. Zebol, Duyen H. Pham, John W. Finnie, Anthony S. Don, Lisa M. Ebert, Claudine S. Bonder, Briony L. Gliddon, Stuart M. Pitson

Published Mar 11, 2015 · Vol. 6, No. 9 · pp. 7065-7083

Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells Research Paper

Camille LoubiÃ¨re, Thomas Goiran, Kathiane Laurent, Zied Djabari, Jean-FranÃ§ois Tanti, FrÃ©dÃ©ric Bost

Published Mar 10, 2015 · Vol. 6, No. 17 · pp. 15652-15661

Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells Research Paper

Dominique Thuringer, Kevin Berthenet, Laurent Cronier, Gaetan Jego, Eric Solary, Carmen Garrido

Published Mar 10, 2015 · Vol. 6, No. 12 · pp. 10267-10283

Enzastaurin inhibits ABCB1-mediated drug efflux independently of effects on protein kinase C signalling and the cellular p53 status Research Paper

Martin Michaelis, Florian Rothweiler, Nadine LÃ¶schmann, Mohsen Sharifi, Taravat Ghafourian, Jindrich Cinatl Jr.

Published Feb 13, 2015 · Vol. 6, No. 19 · pp. 17605-17620

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia Research Paper

Alisa B. Lee-Sherick, Weihe Zhang, Kelly K. Menachof, Amanda A. Hill, Sean Rinella, Gregory Kirkpatrick, Lauren S. Page, Michael A. Stashko, Craig T. Jordan, Qi Wei, Jing Liu, Dehui Zhang, Deborah DeRyckere, Xiaodong Wang, Stephen Frye, H. Shelton Earp, Douglas K. Graham

Published Feb 10, 2015 · Vol. 6, No. 9 · pp. 6722-6736

H89 enhances the sensitivity of cancer cells to glyceryl trinitrate through a purinergic receptor-dependent pathway Research Paper

Marion Cortier, Rahamata Boina-Ali, Cindy Racoeur, Catherine Paul, Eric Solary, Jean-FranÃ§ois Jeannin, Ali Bettaieb

Published Feb 4, 2015 · Vol. 6, No. 9 · pp. 6877-6886

DC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2 Research Paper

Juan Qin, Jiao Ji, Rong Deng, Jun Tang, Fen Yang, Gong-Kan Feng, Wen-Dan Chen, Xiao-Qi Wu, Xiao-Jun Qian, Ke Ding, Xiao-Feng Zhu

Published Feb 4, 2015 · Vol. 6, No. 9 · pp. 6944-6958

Protein kinase CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and propels malignant B-cell growth Research Paper

Marco Pizzi, Francesco Piazza, Claudio Agostinelli, Fabio Fuligni, Pietro Benvenuti, Elisa Mandato, Alessandro Casellato, Massimo Rugge, Gianpietro Semenzato, Stefano A. Pileri

Published Jan 31, 2015 · Vol. 6, No. 9 · pp. 6544-6552

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Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients Research Paper

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells Research Paper

Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter Research Paper

Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer Research Paper

Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models Priority Research Paper

AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts Priority Research Paper

Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism Research Paper

The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2 Research Paper

A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging Research Paper

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab Research Paper

Targeting AMPK for cancer prevention and treatment Review

RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer Research Paper

A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties Research Paper

Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells Research Paper

Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells Research Paper

Enzastaurin inhibits ABCB1-mediated drug efflux independently of effects on protein kinase C signalling and the cellular p53 status Research Paper

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia Research Paper

H89 enhances the sensitivity of cancer cells to glyceryl trinitrate through a purinergic receptor-dependent pathway Research Paper

DC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2 Research Paper

Protein kinase CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and propels malignant B-cell growth Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients Research Paper

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells Research Paper

Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter Research Paper

Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer Research Paper

Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models Priority Research Paper

AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts Priority Research Paper

Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism Research Paper

The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2 Research Paper

A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging Research Paper

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab Research Paper

Targeting AMPK for cancer prevention and treatment Review

RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer Research Paper

A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties Research Paper

Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells Research Paper

Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells Research Paper

Enzastaurin inhibits ABCB1-mediated drug efflux independently of effects on protein kinase C signalling and the cellular p53 status Research Paper

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia Research Paper

H89 enhances the sensitivity of cancer cells to glyceryl trinitrate through a purinergic receptor-dependent pathway Research Paper

DC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2 Research Paper

Protein kinase CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and propels malignant B-cell growth Research Paper