The Oncosearch | Oncotarget

Salmonella VNP20009-mediated RNA interference of ABCB5 moderated chemoresistance of melanoma stem cell and suppressed tumor growth more potently Research Paper

Xiaoxin Zhang, Xiawei Cheng, Yueyang Lai, Yuqiang Zhou, Wenmin Cao, Zi-Chun Hua

Published Feb 19, 2016 · Vol. 7, No. 12 · pp. 14940-14950

Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport Research Paper

Martin Michaelis, Florian Rothweiler, Mario Wurglics, NatÃ¡lia Aniceto, Michaela Dittrich, Heiko Zettl, Michael Wiese, Mark Wass, Taravat Ghafourian, Manfred Schubert-Zsilavecz, Jindrich Cinatl

Published Feb 12, 2016 · Vol. 7, No. 10 · pp. 11664-11676

Multi-kinase inhibitors can associate with heat shock proteins through their NH₂-termini by which they suppress chaperone function Research Paper

Laurence Booth, Brian Shuch, Thomas Albers, Jane L. Roberts, Mehrad Tavallai, Stefan Proniuk, Alexander Zukiwski, Dasheng Wang, Ching-Shih Chen, Don Bottaro, Heath Ecroyd, Iryna O. Lebedyeva, Paul Dent

Published Feb 12, 2016 · Vol. 7, No. 11 · pp. 12975-12996

Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate Research Paper

PaweÅ‚ Lis, PaweÅ‚ Jurkiewicz, Magdalena Cal-BÄ…kowska, Young H. Ko, Peter L. Pedersen, Andre Goffeau, StanisÅ‚aw UÅ‚aszewski

Published Feb 3, 2016 · Vol. 7, No. 9 · pp. 10153-10173

Transtinib, a potent tyrosine kinase inhibitor inhibits L858R/T790M mutant NSCLC cell lines and xenografts Research Paper

Peng Hu, Da-xiong Han, Run-sheng Ruan, Li-Mou Zheng, Shiu-Huey Chou, Chi-Meng Tzeng

Published Feb 2, 2016 · Vol. 7, No. 24 · pp. 35741-35752

Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells Research Paper

Jennifer Varin, Laury Poulain, Mikael Hivelin, Patrick Nusbaum, Arnaud Hubas, Ingrid Laurendeau, Laurent Lantieri, Pierre Wolkenstein, Michel Vidaud, Eric Pasmant, Nicolas Chapuis, BÃ©atrice Parfait

Published Jan 31, 2016 · Vol. 7, No. 24 · pp. 35753-35767

A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function Research Paper

Gang Chen, Junhua Liu, Wantao Chen, Qin Xu, Meng Xiao, Lihong Hu, Li Mao, Xu Wang

Published Jan 25, 2016 · Vol. 7, No. 8 · pp. 9388-9403

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma Research Paper

Milica Stefanovic, Anna Tutusaus, Guillermo A. Martinez-Nieto, Cristina BÃ¡rcena, Estefania de Gregorio, Catia Moutinho, Elisabet Barbero-Camps, Alberto Villanueva, Anna Colell, Montserrat MarÃ, Carmen GarcÃa-Ruiz, Jose C. Fernandez-Checa, Albert Morales

Published Jan 22, 2016 · Vol. 7, No. 7 · pp. 8253-8267

Rh2E2, a novel metabolic suppressor, specifically inhibits energy-based metabolism of tumor cells Research Paper

Vincent Kam Wai Wong, Hang Dong, Xu Liang, Li-Ping Bai, Zhi-Hong Jiang, Yue Guo, Ah-Ng Tony Kong, Rui Wang, Richard Kin Ting Kam, Betty Yuen Kwan Law, Wendy Wen Luen Hsiao, Ka Man Chan, Jingrong Wang, Rick Wai Kit Chan, Jianru Guo, Wei Zhang, Feng Gen Yen, Hua Zhou, Elaine Lai Han Leung, Zhiling Yu, Liang Liu

Published Jan 18, 2016 · Vol. 7, No. 9 · pp. 9907-9924

Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes Research Paper

Gloria Castellano-GonzÃ¡lez, Nicolas Pichaud, J. William O. Ballard, Alban Bessede, Helder Marcal, Gilles J. Guillemin

Published Jan 9, 2016 · Vol. 7, No. 7 · pp. 7426-7440

HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress Research Paper

Ming-Da Wang, Han Wu, Shuai Huang, Hui-Lu Zhang, Chen-Jie Qin, Ling-Hao Zhao, Gong-Bo Fu, Xu Zhou, Xian-Ming Wang, Liang Tang, Wen Wen, We Yang, Shan-Hua Tang, Dan Cao, Lin-Na Guo, Min Zeng, Meng-Chao Wu, He-Xin Yan, Hong-Yang Wang

Published Jan 4, 2016 · Vol. 7, No. 6 · pp. 6711-6726

Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer Research Paper

Huanjie Shao, Esraa M. Mohamed, Guoyan G. Xu, Michael Waters, Kai Jing, Yibao Ma, Yan Zhang, Sarah Spiegel, Michael O. Idowu, Xianjun Fang

Published Dec 24, 2015 · Vol. 7, No. 4 · pp. 3832-3846

Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions Research Paper

Xiao-Man Liu, Yong-Ping Zhang, Shu-Yan Ji, Bo-Tai Li, Xuejun Tian, Dali Li, Chao Tong, Heng-Yu Fan

Published Dec 21, 2015 · Vol. 7, No. 2 · pp. 1155-1167

miR-101 reverses hypomethylation of the PRDM16 promoter to disrupt mitochondrial function in astrocytoma cells Research Paper

Qianqian Lei, Xiaoping Liu, Haijuan Fu, Yingnan Sun, Liping Wang, Gang Xu, Wei Wang, Zhibin Yu, Changhong Liu, Peiyao Li, Jianbo Feng, Guiyuan Li, Minghua Wu

Published Dec 18, 2015 · Vol. 7, No. 4 · pp. 5007-5022

Recurrent AKT mutations in human cancers: functional consequences and effects on drug sensitivity Research Paper

Kyung H. Yi, Josh Lauring

Published Dec 17, 2015 · Vol. 7, No. 4 · pp. 4241-4251

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway Research Paper

Ning Tang, Lei Shi, Zhenlong Yu, Peipei Dong, Chao Wang, Xiaokui Huo, Baojing Zhang, Shanshan Huang, Sa Deng, Kexin Liu, Tonghui Ma, Xiaobo Wang, Lijun Wu, Xiaochi Ma

Published Dec 9, 2015 · Vol. 7, No. 3 · pp. 3533-3547

Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model Research Paper

Giovanna Sociali, Lizzia Raffaghello, Mirko Magnone, Federica Zamporlini, Laura Emionite, Laura Sturla, Giovanna Bianchi, Tiziana Vigliarolo, Aimable Nahimana, Alessio Nencioni, Nadia Raffaelli, Santina Bruzzone

Published Dec 8, 2015 · Vol. 7, No. 3 · pp. 2968-2984

Obg-like ATPase 1 regulates global protein serine/threonine phosphorylation in cancer cells by suppressing the GSK3Î²-inhibitor 2-PP1 positive feedback loop Research Paper

Dong Xu, Renduo Song, Guohui Wang, Prince V.S. Jeyabal, Amanda M. Weiskoff, Kefeng Ding, Zheng-Zheng Shi

Published Dec 7, 2015 · Vol. 7, No. 3 · pp. 3427-3439

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy Research Paper

Gerald Goh, Trent Walradt, Vladimir Markarov, Astrid Blom, Nadeem Riaz, Ryan Doumani, Krista Stafstrom, Ata Moshiri, Lola Yelistratova, Jonathan Levinsohn, Timothy A. Chan, Paul Nghiem, Richard P. Lifton, Jaehyuk Choi

Published Dec 7, 2015 · Vol. 7, No. 3 · pp. 3403-3415

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

Serguei A. Gordeev, Tatiana V. Bykova, Svetlana G. Zubova, Olga A. Bystrova, Marina G. Martynova, Valery A. Pospelov, Tatiana V. Pospelova

Published Dec 4, 2015 · Vol. 6, No. 42 · pp. 44905-44926

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Salmonella VNP20009-mediated RNA interference of ABCB5 moderated chemoresistance of melanoma stem cell and suppressed tumor growth more potently Research Paper

Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport Research Paper

Multi-kinase inhibitors can associate with heat shock proteins through their NH₂-termini by which they suppress chaperone function Research Paper

Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate Research Paper

Transtinib, a potent tyrosine kinase inhibitor inhibits L858R/T790M mutant NSCLC cell lines and xenografts Research Paper

Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells Research Paper

A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function Research Paper

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma Research Paper

Rh2E2, a novel metabolic suppressor, specifically inhibits energy-based metabolism of tumor cells Research Paper

Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes Research Paper

HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress Research Paper

Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer Research Paper

Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions Research Paper

miR-101 reverses hypomethylation of the PRDM16 promoter to disrupt mitochondrial function in astrocytoma cells Research Paper

Recurrent AKT mutations in human cancers: functional consequences and effects on drug sensitivity Research Paper

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway Research Paper

Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model Research Paper

Obg-like ATPase 1 regulates global protein serine/threonine phosphorylation in cancer cells by suppressing the GSK3Î²-inhibitor 2-PP1 positive feedback loop Research Paper

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy Research Paper

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Salmonella VNP20009-mediated RNA interference of ABCB5 moderated chemoresistance of melanoma stem cell and suppressed tumor growth more potently Research Paper

Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport Research Paper

Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function Research Paper

Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate Research Paper

Transtinib, a potent tyrosine kinase inhibitor inhibits L858R/T790M mutant NSCLC cell lines and xenografts Research Paper

Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells Research Paper

A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function Research Paper

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma Research Paper

Rh2E2, a novel metabolic suppressor, specifically inhibits energy-based metabolism of tumor cells Research Paper

Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes Research Paper

HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress Research Paper

Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer Research Paper

Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions Research Paper

miR-101 reverses hypomethylation of the PRDM16 promoter to disrupt mitochondrial function in astrocytoma cells Research Paper

Recurrent AKT mutations in human cancers: functional consequences and effects on drug sensitivity Research Paper

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway Research Paper

Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model Research Paper

Obg-like ATPase 1 regulates global protein serine/threonine phosphorylation in cancer cells by suppressing the GSK3Î²-inhibitor 2-PP1 positive feedback loop Research Paper

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy Research Paper

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

Multi-kinase inhibitors can associate with heat shock proteins through their NH₂-termini by which they suppress chaperone function Research Paper