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Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer. See Jezkova et al.
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Table of Contents
Editorial: Immunology
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| CXCL10 and bloodbrain barrier modulation in rabies virus infection |
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https://doi.org/10.18632/oncotarget.7428
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| 10694-10695 |
Priority Research Papers
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| A syntheticlethality RNAi screen reveals an ERKmTOR cotargeting proapoptotic switch in PIK3CA+ oral cancers |
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https://doi.org/10.18632/oncotarget.7372
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| 10696-10709 |
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| Aryl hydrocarbon receptor nuclear translocator ARNT isoforms control lymphoid cancer cell proliferation through differentially regulating tumor suppressor p53 activity |
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https://doi.org/10.18632/oncotarget.7539
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| 10710-10722 |
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| MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency |
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https://doi.org/10.18632/oncotarget.7561
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| 10723-10738 |
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| MPL W515L expression induces TGFβ secretion and leads to an increase in chemokinesis via phosphorylation of THOC5 |
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https://doi.org/10.18632/oncotarget.7639
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| 10739-10755 |
Research Papers: Gerotarget (Focus on Aging)
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| NFE2L2 variations reduce antioxidant response in patients with Parkinson disease |
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https://doi.org/10.18632/oncotarget.7353
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| 10756-10764 |
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| DNA methylation in PRDM8 is indicative for dyskeratosis congenita |
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https://doi.org/10.18632/oncotarget.7458
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| 10765-10772 |
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| Metformin regulates oxLDLfacilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX1modulated oxidative signaling |
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https://doi.org/10.18632/oncotarget.7387
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| 10773-10787 |
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| Identity proliferation capacity genomic stability and novel senescence markers of mesenchymal stem cells isolated from low volume of human bone marrow |
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https://doi.org/10.18632/oncotarget.7456
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| 10788-10802 |
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| Identification of long noncoding RNAs as novel biomarker and potential therapeutic target for atrial fibrillation in old adults |
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https://doi.org/10.18632/oncotarget.7514
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| 10803-10811 |
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| Stress resistance and lifespan are increased in C elegans but decreased in S cerevisiae by mafr1/maf1 deletion |
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https://doi.org/10.18632/oncotarget.7769
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| 10812-10826 |
Research Papers: Pathology
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| Construction and analysis of cardiac hypertrophyassociated lncRNAmRNA network based on competitive endogenous RNA reveal functional lncRNAs in cardiac hypertrophy |
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https://doi.org/10.18632/oncotarget.7312
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| 10827-10840 |
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| Targeting cfms kinase attenuates chronic aristolochic acid nephropathy in mice |
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https://doi.org/10.18632/oncotarget.7460
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| 10841-10856 |
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| An efficient model of human endometriosis by induced unopposed estrogenicity in baboons |
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https://doi.org/10.18632/oncotarget.7516
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| 10857-10869 |
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| miR19b attenuates H2O2induced apoptosis in rat H9C2 cardiomyocytes via targeting PTEN |
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https://doi.org/10.18632/oncotarget.7678
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| 10870-10878 |
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| Acidic leucinerich nuclear phosphoprotein32A ANP32A association with lymph node metastasis predicts poor survival in oral squamous cell carcinoma patients |
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https://doi.org/10.18632/oncotarget.7681
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| 10879-10890 |
Research Papers: Immunology
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| The impact of ranitidine on monocyte responses in the context of solid tumors |
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https://doi.org/10.18632/oncotarget.7211
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| 10891-10904 |
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| Immunogenicity and safety of xenogeneic vascular endothelial growth factor receptor2 DNA vaccination in mice and dogs |
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https://doi.org/10.18632/oncotarget.7265
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| 10905-10916 |
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| First indepth analysis of the novel Th2type cytokines in salmonid fish reveals distinct patterns of expression and modulation but overlapping bioactivities |
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https://doi.org/10.18632/oncotarget.7295
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| 10917-10946 |
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| Compensatory roles of CD8+ T cells and plasmacytoid dendritic cells in gut immune regulation for reduced function of CD4+ Tregs |
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https://doi.org/10.18632/oncotarget.7510
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| 10947-10961 |
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| Removal of regulatory T cells prevents secondary chronic infection but increases the mortality of subsequent subacute infection in sepsis mice |
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https://doi.org/10.18632/oncotarget.7682
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| 10962-10975 |
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| Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients |
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https://doi.org/10.18632/oncotarget.7686
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| 10976-10989 |
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| New pathogenspecific immunoPET/MR tracer for molecular imaging of a systemic bacterial infection |
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https://doi.org/10.18632/oncotarget.7770
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| 10990-11001 |
Reviews
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| Cancer stem cells and signaling pathways in radioresistance |
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https://doi.org/10.18632/oncotarget.6760
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| 11002-11017 |
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| Aldehyde dehydrogenase 1A1 in stem cells and cancer |
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https://doi.org/10.18632/oncotarget.6920
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| 11018-11032 |
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| The role of small adaptor proteins in the control of oncogenic signaling driven by tyrosine kinases in human cancer |
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https://doi.org/10.18632/oncotarget.6929
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| 11033-11055 |
Research Papers
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| Gainoffunction miRNA signature by mutant p53 associates with poor cancer outcome |
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https://doi.org/10.18632/oncotarget.7090
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| 11056-11066 |
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| Oxidation of heat shock protein 60 and protein disulfide isomerase activates ERK and migration of human hepatocellular carcinoma HepG2 |
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https://doi.org/10.18632/oncotarget.7093
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| 11067-11082 |
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| Tumorinfiltrating macrophages express interleukin25 and predict a favorable prognosis in patients with gastric cancer after radical resection |
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https://doi.org/10.18632/oncotarget.7095
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| 11083-11093 |
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| Loss of oncogenic miR155 in tumor cells promotes tumor growth by enhancing C/EBPβmediated MDSC infiltration |
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https://doi.org/10.18632/oncotarget.7150
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| 11094-11112 |
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| Overexpression of lipocalin 2 in human cervical cancer enhances tumor invasion |
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https://doi.org/10.18632/oncotarget.7096
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| 11113-11126 |
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| Aberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpression |
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https://doi.org/10.18632/oncotarget.7152
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| 11127-11136 |
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| Bevacizumab specifically decreases elevated levels of circulating KIT+CD11b+ cells and IL10 in metastatic breast cancer patients |
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https://doi.org/10.18632/oncotarget.7097
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| 11137-11150 |
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| A systematic review of serum autoantibodies as biomarkers for pancreatic cancer detection |
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https://doi.org/10.18632/oncotarget.7098
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| 11151-11164 |
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| Distinct lymphocyte antigens 6 Ly6 family members Ly6D Ly6E Ly6K and Ly6H drive tumorigenesis and clinical outcome |
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https://doi.org/10.18632/oncotarget.7163
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| 11165-11193 |
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| EZH2 promotes cell migration and invasion but not alters cell proliferation by suppressing Ecadherin partly through association with MALAT1 in pancreatic cancer |
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https://doi.org/10.18632/oncotarget.7156
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| 11194-11207 |
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| Smad4dependent suppressor pituitary homeobox 2 promotes PPP2R2Amediated inhibition of Akt pathway in pancreatic cancer |
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https://doi.org/10.18632/oncotarget.7158
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| 11208-11222 |
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| Brother of the regulator of the imprinted site BORIS variant subfamily 6 is involved in cervical cancer stemness and can be a target of immunotherapy |
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https://doi.org/10.18632/oncotarget.7165
|
| 11223-11237 |
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| HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells |
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https://doi.org/10.18632/oncotarget.7167
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| 11238-11250 |
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| Mucin glycosylating enzyme GALNT2 suppresses malignancy in gastric adenocarcinoma by reducing MET phosphorylation |
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https://doi.org/10.18632/oncotarget.7081
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| 11251-11262 |
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| Identification of quinazoline compounds as novel potent inhibitors of Wnt/βcatenin signaling in colorectal cancer cells |
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https://doi.org/10.18632/oncotarget.7019
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| 11263-11270 |
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| Long noncoding RNA FEZF1AS1 facilitates cell proliferation and migration in colorectal carcinoma |
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https://doi.org/10.18632/oncotarget.7168
|
| 11271-11283 |
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| SIRT1 increases YAP and MKK3dependent p38 phosphorylation in mouse liver and human hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.7022
|
| 11284-11298 |
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| Heparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cells |
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https://doi.org/10.18632/oncotarget.7170
|
| 11299-11309 |
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| Dosing de novo combinations of two targeted drugs: Towards a customized precision medicine approach to advanced cancers |
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https://doi.org/10.18632/oncotarget.7023
|
| 11310-11320 |
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| EIF2S3Y suppresses the pluripotency state and promotes the proliferation of mouse embryonic stem cells |
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https://doi.org/10.18632/oncotarget.7187
|
| 11321-11331 |
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| Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stemlike cells |
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https://doi.org/10.18632/oncotarget.7238
|
| 11332-11348 |
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| Mutual amplification of HNF4α and IL1R1 composes an inflammatory circuit in Helicobacter pylori associated gastric carcinogenesis |
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https://doi.org/10.18632/oncotarget.7239
|
| 11349-11363 |
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| Human telomerase reverse transcriptase hTERT promotes gastric cancer invasion through cooperating with cMyc to upregulate heparanase expression |
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https://doi.org/10.18632/oncotarget.6575
|
| 11364-11379 |
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| Efficacy of continued cetuximab for unresectable metastatic colorectal cancer after disease progression during firstline cetuximabbased chemotherapy: a retrospective cohort study |
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https://doi.org/10.18632/oncotarget.7193
|
| 11380-11396 |
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| Pinin interacts with Cterminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells |
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https://doi.org/10.18632/oncotarget.7242
|
| 11397-11411 |
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| Oncogenic potential of histonevariant H2AZ1 and its regulatory role in cell cycle and epithelialmesenchymal transition in liver cancer |
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https://doi.org/10.18632/oncotarget.7194
|
| 11412-11423 |
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| Polycomb repressor complex 1 promotes gene silencing through H2AK119 monoubiquitination in acinartoductal metaplasia and pancreatic cancer cells |
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https://doi.org/10.18632/oncotarget.6717
|
| 11424-11433 |
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| Examining plasma microRNA markers for colorectal cancer at different stages |
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https://doi.org/10.18632/oncotarget.7196
|
| 11434-11449 |
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| Frequency of CD4+CD25+Foxp3+ cells in peripheral blood in relation to urinary bladder cancer malignancy indicators before and after surgical removal |
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https://doi.org/10.18632/oncotarget.7199
|
| 11450-11462 |
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| Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity |
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https://doi.org/10.18632/oncotarget.7201
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| 11463-11477 |
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| Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer |
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https://doi.org/10.18632/oncotarget.7202
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| 11478-11486 |
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| Noncoding RNA LINC00857 is predictive of poor patient survival and promotes tumor progression via cell cycle regulation in lung cancer |
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https://doi.org/10.18632/oncotarget.7203
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| 11487-11499 |
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| Defining specificity and ontarget activity of BH3mimetics using engineered BALL cell lines |
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https://doi.org/10.18632/oncotarget.7204
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| 11500-11511 |
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| Role of MIF/CD74 signaling pathway in the development of pleural mesothelioma |
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https://doi.org/10.18632/oncotarget.7314
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| 11512-11525 |
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| Integrative radiogenomic analysis for multicentric radiophenotype in glioblastoma |
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https://doi.org/10.18632/oncotarget.7115
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| 11526-11538 |
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| Identification of novel pathways linking epithelialtomesenchymal transition with resistance to HER2targeted therapy |
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https://doi.org/10.18632/oncotarget.7317
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| 11539-11552 |
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| Regulation of laryngeal squamous cell cancer progression by the lncRNA H19/miR148a3p/DNMT1 axis |
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https://doi.org/10.18632/oncotarget.7270
|
| 11553-11566 |
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| HIF3α1 promotes colorectal tumor cell growth by activation of JAKSTAT3 signaling |
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https://doi.org/10.18632/oncotarget.7272
|
| 11567-11579 |
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| A strategy to eradicate welldeveloped Krebs2 ascites in mice |
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https://doi.org/10.18632/oncotarget.7311
|
| 11580-11594 |
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| MicroRNA150 suppresses cell proliferation and metastasis in hepatocellular carcinoma by inhibiting the GAB1ERK axis |
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https://doi.org/10.18632/oncotarget.7292
|
| 11595-11608 |
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| Downregulation of TFAM inhibits the tumorigenesis of nonsmall cell lung cancer by activating ROSmediated JNK/p38MAPK signaling and reducing cellular bioenergetics |
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https://doi.org/10.18632/oncotarget.7018
|
| 11609-11624 |
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| Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NFκB pathway |
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https://doi.org/10.18632/oncotarget.7299
|
| 11625-11636 |
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| miR1443p a tumor suppressive microRNA targeting ETS1 in laryngeal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.7025
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| 11637-11650 |
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| Hypoxia induces TFE3 expression in head and neck squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.7309
|
| 11651-11663 |
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| Substratespecific effects of pirinixic acid derivatives on ABCB1mediated drug transport |
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https://doi.org/10.18632/oncotarget.7345
|
| 11664-11676 |
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| CCL34 a synthetic tolllike receptor 4 activator modulates differentiation and maturation of myeloid dendritic cells |
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https://doi.org/10.18632/oncotarget.7315
|
| 11677-11686 |
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| Antidepressants in association with reducing risk of oral cancer occurrence: a nationwide populationbased cohort and nested casecontrol studies |
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https://doi.org/10.18632/oncotarget.7049
|
| 11687-11695 |
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| Long noncoding RNA LINC01133 represses KLF2 P21 and Ecadherin transcription through binding with EZH2 LSD1 in non small cell lung cancer |
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https://doi.org/10.18632/oncotarget.7077
|
| 11696-11707 |
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| Overcoming chemo/radioresistance of pancreatic cancer by inhibiting STAT3 signaling |
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https://doi.org/10.18632/oncotarget.7336
|
| 11708-11723 |
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| XPG rs2296147 T>C polymorphism predicted clinical outcome in colorectal cancer |
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https://doi.org/10.18632/oncotarget.7352
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| 11724-11732 |
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| Long noncoding RNA MALAT1 increases AKAP9 expression by promoting SRPK1catalyzed SRSF1 phosphorylation in colorectal cancer cells |
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https://doi.org/10.18632/oncotarget.7367
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| 11733-11743 |
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