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Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Quantitative analysis of the hierarchical distribution of 5hmC in stratified epithelia. Representative micrograph of normal prostate epithelia co-immunolabeled for 5hmC (red) and basal cell specific cytokeratin 903 (green). Nuclei were counterstained with DAPI (blue). See Haffner et al.
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Table of Contents
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| Inhibition of Wnt signaling and cancer stem cells |
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https://doi.org/10.18632/oncotarget.309
Desheng Lu, and Dennis A. Carson
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| 587 |
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| Unraveling the complexity of basallike breast cancer |
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https://doi.org/10.18632/oncotarget.314
Lauren L. C. Marotta, and Kornelia Polyak
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| 588-589 |
Reviews
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| Mouse Models to Interrogate the Implications of the Differentiation Status In the Ontogeny of Gliomas |
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https://doi.org/10.18632/oncotarget.319
Diana Marcela Muñoz, and Abhijit Guha
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| 590-598 |
Research Papers
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| Aurora Kinase Inhibition Overcomes Cetuximab Resistance in Squamous Cell Cancer of the Head and Neck |
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https://doi.org/10.18632/oncotarget.311
Alexander Hoellein, Anja Pickhard, Fabienne von Keitz, Stephanie Schoeffmann, Guido Piontek, Martina Rudelius, Anja Baumgart, Stefan Wagenpfeil, Christian Peschel, Tobias Dechow, Henning Bier, and Ulrich Keller
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| 599-609 |
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| Cooperative Effects of Akt1 and Raf1 on the Induction of Cellular Senescence in Doxorubicin or Tamoxifen Treated Breast Cancer Cells |
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https://doi.org/10.18632/oncotarget.315
Jackson R. Taylor, Brian D. Lehmann, William H. Chappell, Stephen L. Abrams, Linda S. Steelman, and James A. McCubrey
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| 610-626 |
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| Global 5hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers |
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https://doi.org/10.18632/oncotarget.316
Michael Christoph Haffner, Alcides Chaux, Alan K Meeker, David Esopi, Jonathan Gerber, Laxmi G. Pellakuru, Antoun Toubaji, Pedram Argani, Christine Iacobuzio-Donahue, William G. Nelson, George J. Netto, Angelo DeMarzo, and Srinivasan Yegnasubramanian
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| 627-637 |
Research Perspectives
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| The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer |
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https://doi.org/10.18632/oncotarget.310
Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi, and Janet A. Houghton
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| 638-645 |
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| The NFκB pathway: a therapeutic target in glioblastoma |
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https://doi.org/10.18632/oncotarget.322
Lorena Nogueira, Patricia Ruiz-Ontañon, Alfonso Vazquez-Barquero, Francisco Moris, and Jose L. Fernandez-Luna
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| 646-653 |
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