Oncotarget

Vol 12, No 21

October 12, 2021

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About The Cover

The cover for issue 21 of Oncotarget features Figure 6, "MGMTlow/MMRproficient/LOHhigh PDX models are responsive to the TMZ + ATRi combination," by El Touny, et al. .

Table of Contents

Priority Research Papers

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide

https://doi.org/10.18632/oncotarget.28090

Lara H. El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B. Dull, Deborah F. Wilsker, Melinda G. Hollingshead, Michelle Gottholm-Ahalt, Sergio Y. Alcoser, Michael E. Mullendore, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher,  and Annamaria Rapisarda
2114-2130
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Research Papers

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab

https://doi.org/10.18632/oncotarget.28086

Ilyas Sahin, Andrew George, Shengliang Zhang, Kelsey E. Huntington, Zehra Ordulu, Lanlan Zhou,  and Wafik S. El-Deiry
2131-2146
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors

https://doi.org/10.18632/oncotarget.28078

Edmond J. Feris, John W. Hinds,  and Michael D. Cole
2147-2157
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan

https://doi.org/10.18632/oncotarget.28073

Erling Håland, Ingrid Nyhus Moen, Elias Veidal, Hanne Hella, Kristine Misund, Tobias S. Slørdahl,  and Kristian K. Starheim
2158-2168
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey

The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey

https://doi.org/10.18632/oncotarget.28076

Subotheni Thavaneswaran, Mandy Ballinger, Phyllis Butow, Bettina Meiser, David Goldstein, Frank Lin, Christine Napier, David Thomas,  and Megan Best
2169-2176
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Low tumour-infiltrating lymphocyte density in primary and recurrent glioblastoma

Low tumour-infiltrating lymphocyte density in primary and recurrent glioblastoma

https://doi.org/10.18632/oncotarget.28069

Kelsey Maddison, Moira C. Graves, Nikola A. Bowden, Michael Fay, Ricardo E. Vilain, Sam Faulkner,  and Paul A. Tooney
2177-2187
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers

https://doi.org/10.18632/oncotarget.28064

Sayantani Chatterjee, Julian Ugonotti, Ling Y. Lee, Arun Everest-Dass, Rebeca Kawahara,  and Morten Thaysen-Andersen
2188-2205
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release  |  Order a Reprint

TP53 mutations determined by targeted NGS in breast cancer: a case-control study

TP53 mutations determined by targeted NGS in breast cancer: a case-control study

https://doi.org/10.18632/oncotarget.28071

Angeliki Andrikopoulou, Evangelos Terpos, Spyridoula Chatzinikolaou, Kleoniki Apostolidou, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Meletios-Athanasios Dimopoulos,  and Flora Zagouri
2206-2214
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Association of four genetic variants with colorectal cancer in Kazakhstan population

Association of four genetic variants with colorectal cancer in Kazakhstan population

https://doi.org/10.18632/oncotarget.28070

Yevgeniya Kolesnikova, Dmitriy Babenko, Irina Kadyrova, Svetlana Kolesnichenko, Lyudmila Akhmaltdinova, Ilya Korshukov, Naylya Kabildina, Valentina Sirota, Vera Zhumaliyeva, Dana Taizhanova, Dmitriy Vazenmiller,  and Anar Turmukhambetova
2215-2222
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release  |  Order a Reprint

Editorial

Javelin Head Neck 100: Should we combine immunotherapy with radiation therapy?

Javelin Head Neck 100: Should we combine immunotherapy with radiation therapy?

https://doi.org/10.18632/oncotarget.27987

Yao Yu, Kaveh Zakeri,  and Nancy Lee
2223-2226
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Research Perspectives

Neddylation and anti-tumor immunity

Neddylation and anti-tumor immunity

https://doi.org/10.18632/oncotarget.28019

Xiaoguang Wang, Scott Best,  and Alexey V. Danilov
2227-2230
Abstract  |  PDF  |  Full Text  |  How to cite  |  Order a Reprint

Corrections

Correction: Discovery and clinical introduction of first-in-class imipridone ONC201

Correction: Discovery and clinical introduction of first-in-class imipridone ONC201

https://doi.org/10.18632/oncotarget.28012

Joshua E. Allen, C. Leah B. Kline, Varun V. Prabhu, Jessica Wagner, Jo Ishizawa, Neel Madhukar, Avital Lev, Marie Baumeister, Lanlan Zhou, Amriti Lulla, Martin Stogniew, Lee Schalop, Cyril Benes, Howard L. Kaufman, Richard S. Pottorf, B. Rao Nallaganchu, Gary L. Olson, Fahd Al-Mulla, Madeleine Duvic, Gen Sheng Wu, David T. Dicker, Mala K. Talekar, Bora Lim, Olivier Elemento, Wolfgang Oster, Joseph Bertino, Keith Flaherty, Michael L. Wang, Gautam Borthakur, Michael Andreeff, Mark Stein,  and Wafik S. El-Deiry
2231-2231
Correction  |  PDF  |  How to cite

Correction: Lipolysis-stimulated lipoprotein receptor overexpression is a novel predictor of poor clinical prognosis and a potential therapeutic target in gastric cancer

Correction: Lipolysis-stimulated lipoprotein receptor overexpression is a novel predictor of poor clinical prognosis and a potential therapeutic target in gastric cancer

https://doi.org/10.18632/oncotarget.28096

Takahito Sugase, Tsuyoshi Takahashi, Satoshi Serada, Minoru Fujimoto, Tomoharu Ohkawara, Kosuke Hiramatsu, Masahiro Koh, Yurina Saito, Koji Tanaka, Yasuhiro Miyazaki, Tomoki Makino, Yukinori Kurokawa, Makoto Yamasaki, Kiyokazu Nakajima, Kazuhiro Hanazaki, Masaki Mori, Yuichiro Doki,  and Tetsuji Naka
2232-2233
Correction  |  PDF  |  How to cite


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