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J124 and J128 have anti-metastatic efficacy in a metastasis model. (a), Livers of mice treated with J124 and J128 as opposed to vehicle alone show distinctive difference in the number of tumor nodules. (b), Representative liver H&E sections of treated and untreated animals underscore differential liver metastasis load. See Schmidt-Kittler et al. (pp. 339-348) and commentary on p. 315-316 of this issue for details.
pp 315-385

Table of Contents

Commentaries

P3Kα: A Driver of Tumor Metastasis

https://doi.org/10.18632/oncotarget.162

Leigh Zawel
315-316
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The heme oxygenase1 and cFLIP in acute myeloid leukemias: two nonredundant but mutually exclusive cellular safeguards protecting cells against TNFinduced cell death

https://doi.org/10.18632/oncotarget.163

Sarah Shirley, and Olivier Micheau
317-319
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Reviews

Membrane lipids in invadopodia and podosomes: Key structures for cancer invasion and metastasis

https://doi.org/10.18632/oncotarget.164

Hideki Yamaguchi, and Tsukasa Oikawa
320-328
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

CD277 is a negative costimulatory molecule universally expressed by ovarian cancer microenvironmental cells

https://doi.org/10.18632/oncotarget.165

Juan R. Cubillos-Ruiz, Diana Martinez, Uciane K. Scarlett, Melanie R. Rutkowski, Yolanda C. Nesbeth, Ana L. Camposeco-Jacobs, and Jose R. Conejo-Garcia
329-338
Abstract  |  PDF  |  Full Text  |  How to cite

PI3Kα Inhibitors That Inhibit Metastasis

https://doi.org/10.18632/oncotarget.166

Oleg Schmidt-Kittler, Jiuxiang Zhu, Jian Yang, Guosheng Liu, William Hendricks, Christoph Lengauer, Sandra B. Gabelli, Kenneth W. Kinzler, Bert Vogelstein, David L. Huso, and Shibin Zhou
339-348
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR449a causes Rbdependent cell cycle arrest and senescence in prostate cancer cells

https://doi.org/10.18632/oncotarget.167

Emily J. Noonan, Robert F. Place, Shashwati Basak, Deepa Pookot, and Long-Cheng Li
349-358
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FLIP regulation of HO1 and TNF signalling in human acute myeloid leukemia provides a unique secondary antiapoptotic mechanism

https://doi.org/10.18632/oncotarget.168

Stuart A Rushworth, Lyubov Zaitseva, Susana Langa, Kristian M Bowles, and David J MacEwan
359-366
Abstract  |  PDF  |  Full Text  |  How to cite

Research Perspectives

What are genomewide association studies telling us about Bcell tumor development

https://doi.org/10.18632/oncotarget.169

Amy L Sherborne, and Richard S Houlston
367-372
Abstract  |  PDF  |  Full Text  |  How to cite

Mouse models of hepatocarcinogenesis: What can we learn for the prevention of human hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.170

Mihael Vucur, Christoph Roderburg, Kira Bettermann, Frank Tacke, Mathias Heikenwalder, Christian Trautwein, and Tom Luedde
373-378
Abstract  |  PDF  |  Full Text  |  How to cite

The Siah2HIFFoxA2 axis in prostate cancer – new markers and therapeutic opportunities

https://doi.org/10.18632/oncotarget.171

Jianfei Qi, Maurizio Pellecchia, and Ze’ev A. Ronai
379-385
Abstract  |  PDF  |  Full Text  |  How to cite


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