Oncotarget

Vol 9, No 25

April 3, 2018

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About The Cover

The cover for issue 25 of Oncotarget features Figure 2, "Differences between matched and unmatched groups in biomarker statuses, survival, demographics and tumour grade," from Carter, et al.

Table of Contents

Research Papers: Gerotarget (Focus on Aging)

Inhibition of aldose-reductase-2 by a benzofuroxane derivative bf-5m increases the expression of kcne1, kcnq1 in high glucose cultured H9c2 cardiac cells and sudden cardiac death

Inhibition of aldose-reductase-2 by a benzofuroxane derivative bf-5m increases the expression of kcne1, kcnq1 in high glucose cultured H9c2 cardiac cells and sudden cardiac death

https://doi.org/10.18632/oncotarget.23270

Maria Consiglia Trotta, Monica Salerno, Anna Lisa Brigida, Vincenzo Monda, Antonietta Messina, Carmela Fiore, Roberto Avola, Renato Bernardini, Francesco Sessa, Gabriella Marsala, Guido N. Zanghì, Giovanni Messina, Michele D’Amico,  and Clara Di Filippo
17257-17269
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Research Papers: Autophagy and Cell Death

Selective inhibition of BCL-2 is a promising target in patients with high-risk myelodysplastic syndromes and adverse mutational profile

Selective inhibition of BCL-2 is a promising target in patients with high-risk myelodysplastic syndromes and adverse mutational profile

https://doi.org/10.18632/oncotarget.24775

Veronika Reidel, Johanna Kauschinger, Richard T. Hauch, Catharina Müller-Thomas, Niroshan Nadarajah, Rainer Burgkart, Burkhard Schmidt, Dirk Hempel, Anne Jacob, Julia Slotta-Huspenina, Ulrike Höckendorf, Christian Peschel, Wolfgang Kern, Torsten Haferlach, Katharina S. Götze, Stefanie Jilg,  and Philipp J. Jost
17270-17281
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Research Papers

Glioblastoma-specific anti-TUFM nanobody for in-vitro immunoimaging and cancer stem cell targeting

Glioblastoma-specific anti-TUFM nanobody for in-vitro immunoimaging and cancer stem cell targeting

https://doi.org/10.18632/oncotarget.24629

Neja Samec, Ivana Jovcevska, Jure Stojan, Alja Zottel, Mirjana Liovic, Michael P. Myers, Serge Muyldermans, Jernej Šribar, Igor Križaj,  and Radovan Komel
17282-17299
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-21 over-expression and Programmed Cell Death 4 down-regulation features malignant pleural mesothelioma

MiR-21 over-expression and Programmed Cell Death 4 down-regulation features malignant pleural mesothelioma

https://doi.org/10.18632/oncotarget.24644

Lorenzo Nicolè, Rocco Cappellesso, Tiziana Sanavia, Vincenza Guzzardo,  and Ambrogio Fassina
17300-17308
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Characterization of miRNA and their target gene during chicken embryo skeletal muscle development

Characterization of miRNA and their target gene during chicken embryo skeletal muscle development

https://doi.org/10.18632/oncotarget.22457

Endashaw Jebessa, Hongjia Ouyang, Bahareldin Ali Abdalla, Zhenhui Li, Auwalu Yusuf Abdullahi, Qingshen Liu, Qinghua Nie,  and Xiquan Zhang
17309-17324
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3D laparoscopic surgery: a prospective clinical trial

3D laparoscopic surgery: a prospective clinical trial

https://doi.org/10.18632/oncotarget.24669

Antonino Agrusa, Giuseppe Di Buono, Salvatore Buscemi, Gaspare Cucinella, Giorgio Romano,  and Gaspare Gulotta
17325-17333
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Full in-frame exon 3 skipping of BRCA2 confers high risk of breast and/or ovarian cancer

Full in-frame exon 3 skipping of BRCA2 confers high risk of breast and/or ovarian cancer

https://doi.org/10.18632/oncotarget.24671

Sandrine M. Caputo, Mélanie Léone, Francesca Damiola, Asa Ehlen, Aura Carreira, Pascaline Gaidrat, Alexandra Martins, Rita D. Brandão, Ana Peixoto, Ana Vega, Claude Houdayer, Capucine Delnatte, Myriam Bronner, Danièle Muller, Laurent Castera, Marine Guillaud-Bataille, Inge Søkilde, Nancy Uhrhammer, Sophie Demontety, Hélène Tubeuf, Gaïa Castelain, French COVAR group collaborators, Uffe Birk Jensen, Ambre Petitalot, Sophie Krieger, Cédrick Lefol, Virginie Moncoutier, Nadia Boutry-Kryza, Henriette Roed Nielsen, Olga Sinilnikova, Dominique Stoppa-Lyonnet, Amanda B. Spurdle, Manuel R. Teixeira, Florence Coulet, Mads Thomassen,  and Etienne Rouleau
17334-17348
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

In silico prediction of targets for anti-angiogenesis and their in vitro evaluation confirm the involvement of SOD3 in angiogenesis

In silico prediction of targets for anti-angiogenesis and their in vitro evaluation confirm the involvement of SOD3 in angiogenesis

https://doi.org/10.18632/oncotarget.24693

Javier A. García-Vilas, Ian Morilla, Anibal Bueno, Beatriz Martínez-Poveda, Miguel Ángel Medina,  and Juan A.G. Ranea
17349-17367
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An autophagy-related gene expression signature for survival prediction in multiple cohorts of hepatocellular carcinoma patients

An autophagy-related gene expression signature for survival prediction in multiple cohorts of hepatocellular carcinoma patients

https://doi.org/10.18632/oncotarget.24089

Peng Lin, Rong-Quan He, Yi-Wu Dang, Dong-Yue Wen, Jie Ma, Yun He, Gang Chen,  and Hong Yang
17368-17395
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Clinical implication of a quantitative frailty assessment tool for prognosis in patients with urological cancers

Clinical implication of a quantitative frailty assessment tool for prognosis in patients with urological cancers

https://doi.org/10.18632/oncotarget.24712

Osamu Soma, Shingo Hatakeyama, Teppei Okamoto, Naoki Fujita, Teppei Matsumoto, Yuki Tobisawa, Tohru Yoneyama, Hayato Yamamoto, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Shigeyuki Nakaji,  and Chikara Ohyama
17396-17405
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The role of particulate matters on methylation of IFN-γ and IL-4 promoter genes in pediatric allergic rhinitis

The role of particulate matters on methylation of IFN-γ and IL-4 promoter genes in pediatric allergic rhinitis

https://doi.org/10.18632/oncotarget.24227

Youjin Li, Zhe Mu, Hongyang Wang, Jinfen Liu,  and Fan Jiang
17406-17419
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Impact of tobacco smoking on the risk of developing 25 different cancers in the UK: a retrospective study of 422,010 patients followed for up to 30 years

Impact of tobacco smoking on the risk of developing 25 different cancers in the UK: a retrospective study of 422,010 patients followed for up to 30 years

https://doi.org/10.18632/oncotarget.24724

Louis Jacob, Moritz Freyn, Matthias Kalder, Konstantinos Dinas,  and Karel Kostev
17420-17429
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Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholangitis

Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholangitis

https://doi.org/10.18632/oncotarget.24732

Joy Cuenco, Natascha Wehnert, Oleg Blyuss, Anna Kazarian, Harry J. Whitwell, Usha Menon, Anne Dawnay, Michael P. Manns, Stephen P. Pereira,  and John F. Timms
17430-17442
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IL-6 influences the polarization of macrophages and the formation and growth of colorectal tumor

IL-6 influences the polarization of macrophages and the formation and growth of colorectal tumor

https://doi.org/10.18632/oncotarget.24734

Lechuang Chen, Shuren Wang, Yu Wang, Weina Zhang, Kai Ma, Chenfei Hu, Hongxia Zhu, Shufang Liang, Mei Liu,  and Ningzhi Xu
17443-17454
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miRNA-based signatures in cerebrospinal fluid as potential diagnostic tools for early stage Parkinson’s disease

miRNA-based signatures in cerebrospinal fluid as potential diagnostic tools for early stage Parkinson’s disease

https://doi.org/10.18632/oncotarget.24736

Marcia Cristina T. dos Santos, Miguel Arturo Barreto-Sanz, Bruna Renata S. Correia, Rosie Bell, Catherine Widnall, Luis Tosar Perez, Caroline Berteau, Claudia Schulte, Dieter Scheller, Daniela Berg, Walter Maetzler, Pedro A.F. Galante,  and Andre Nogueira da Costa
17455-17465
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FoxM1 is an independent poor prognostic marker and therapeutic target for advanced Middle Eastern breast cancer

FoxM1 is an independent poor prognostic marker and therapeutic target for advanced Middle Eastern breast cancer

https://doi.org/10.18632/oncotarget.24739

Abdul Khalid Siraj, Poyil Pratheeshkumar, Sandeep Kumar Parvathareddy, Zeeshan Qadri, Saravanan Thangavel, Saeeda Ahmed, Fouad Al-Dayel, Asma Tulbah, Dahish Ajarim,  and Khawla S. Al-Kuraya
17466-17482
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Laser ablation is superior to TACE in large-sized hepatocellular carcinoma: a pilot case–control study

Laser ablation is superior to TACE in large-sized hepatocellular carcinoma: a pilot case–control study

https://doi.org/10.18632/oncotarget.24756

Filomena Morisco, Silvia Camera, Maria Guarino, Raffaella Tortora, Valentina Cossiga, Anna Vitiello, Gabriella Cordone, Nicola Caporaso, Giovan Giuseppe Di Costanzo,  and Italian Liver Cancer (ITA.LI.CA) group
17483-17490
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Undetectable or low (<1 ng/ml) postsurgical thyroglobulin values do not rule out metastases in early stage differentiated thyroid cancer patients

Undetectable or low (<1 ng/ml) postsurgical thyroglobulin values do not rule out metastases in early stage differentiated thyroid cancer patients

https://doi.org/10.18632/oncotarget.24766

Alfredo Campennì, Luca Giovanella, Salvatore Antonio Pignata, Antonio Vento, Angela Alibrandi, Letterio Sturiale, Riccardo Laudicella, Alessio Danilo Comis, Rossella Filice, Giuseppe Giuffrida, Maria Elena Stipo, Salvatore Giovinazzo, Francesco Trimarchi, Rosaria Maddalena Ruggeri,  and Sergio Baldari
17491-17500
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BRCA1/2 and TP53 mutation status associates with PD-1 and PD-L1 expression in ovarian cancer

BRCA1/2 and TP53 mutation status associates with PD-1 and PD-L1 expression in ovarian cancer

https://doi.org/10.18632/oncotarget.24770

Verena Wieser, Inge Gaugg, Martina Fleischer, Giridhar Shivalingaiah, Soeren Wenzel, Susanne Sprung, Sigurd F. Lax, Alain G. Zeimet, Heidelinde Fiegl,  and Christian Marth
17501-17511
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The HNF-1β―USP28―Claspin pathway upregulates DNA damage-induced Chk1 activation in ovarian clear cell carcinoma

The HNF-1β―USP28―Claspin pathway upregulates DNA damage-induced Chk1 activation in ovarian clear cell carcinoma

https://doi.org/10.18632/oncotarget.24776

Fuminori Ito, Chiharu Yoshimoto, Yuki Yamada, Tamotsu Sudo,  and Hiroshi Kobayashi
17512-17522
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HLA and killer cell immunoglobulin-like receptor (KIRs) genotyping in patients with acute viral encephalitis

HLA and killer cell immunoglobulin-like receptor (KIRs) genotyping in patients with acute viral encephalitis

https://doi.org/10.18632/oncotarget.24778

Antonino Tuttolomondo, Claudia Colomba, Danilo Di Bona, Alessandra Casuccio, Domenico Di Raimondo, Giuseppe Clemente, Valentina Arnao, Rosaria Pecoraro, Paolo Ragonese, Anna Aiello, Giulia Accardi, Rosario Maugeri, Carlo Maida, Irene Simonetta, Vittoriano Della Corte, Domenico Gerardo Iacopino, Calogero Caruso, Antonio Cascio, Antonio Pinto,  and on behalf of KIRIIND (KIR Infectious and Inflammatory Diseases) Collaborative Group
17523-17532
Abstract  |  PDF  |  HTML  |  Order a Reprint

Risk of sexual transmitted infection following bipolar disorder: a nationwide population-based cohort study

Risk of sexual transmitted infection following bipolar disorder: a nationwide population-based cohort study

https://doi.org/10.18632/oncotarget.24780

Shyh-Chyang Lee, Chang-Kuo Hu, Jeng-Hsiu Hung, Albert C. Yang, Shih-Jen Tsai, Min-Wei Huang, Li-Yu Hu,  and Cheng-Che Shen
17533-17542
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RANTES and IL-6 cooperate in inducing a more aggressive phenotype in breast cancer cells

RANTES and IL-6 cooperate in inducing a more aggressive phenotype in breast cancer cells

https://doi.org/10.18632/oncotarget.24784

Marianna Gallo, Daniela Frezzetti, Cristin Roma, Nicoletta Chicchinelli, Antonio Barbieri, Claudio Arra, Giosuè Scognamiglio, Gerardo Botti, Antonella De Luca,  and Nicola Normanno
17543-17553
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating programmed death ligand-1 (cPD-L1) in non-small-cell lung cancer (NSCLC)

Circulating programmed death ligand-1 (cPD-L1) in non-small-cell lung cancer (NSCLC)

https://doi.org/10.18632/oncotarget.24785

Silvia Vecchiarelli, Francesco Passiglia, Armida D’Incecco, Marianna Gallo, Antonella De Luca, Elisa Rossi, Federica D’Incà, Gabriele Minuti, Lorenza Landi, Chiara Bennati, Michela Spreafico, Manolo D’Arcangelo, Valentina Mazza, Nicola Normanno,  and Federico Cappuzzo
17554-17563
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Sulforaphane suppresses oral cancer cell migration by regulating cathepsin S expression

Sulforaphane suppresses oral cancer cell migration by regulating cathepsin S expression

https://doi.org/10.18632/oncotarget.24786

Chang-Tai Chen, Ming-Ju Hsieh, Yi-Hsien Hsieh, Min-Chieh Hsin, Yi-Ting Chuang, Shun-Fa Yang, Jia-Sin Yang,  and Chiao-Wen Lin
17564-17575
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Gene expression analyses determine two different subpopulations in KIT-negative GIST-like (KNGL) patients

Gene expression analyses determine two different subpopulations in KIT-negative GIST-like (KNGL) patients

https://doi.org/10.18632/oncotarget.24799

David S. Moura, Rafael Ramos, Antonio Fernandez-Serra, Teresa Serrano, Julia Cruz, Ramiro Alvarez-Alegret, Rosa Ortiz-Duran, Luis Vicioso, Maria Luisa Gomez-Dorronsoro, Xavier Garcia del Muro, Javier Martinez-Trufero, Jordi Rubio-Casadevall, Isabel Sevilla, Nuria Lainez, Antonio Gutierrez, Cesar Serrano, Maria Lopez-Alvarez, Nadia Hindi, Miguel Taron, José Antonio López-Guerrero,  and Javier Martin-Broto
17576-17588
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular profiling of advanced breast cancer tumors is beneficial in assisting clinical treatment plans

Molecular profiling of advanced breast cancer tumors is beneficial in assisting clinical treatment plans

https://doi.org/10.18632/oncotarget.24564

Philip Carter, Costi Alifrangis, Biancastella Cereser, Pramodh Chandrasinghe, Lisa Del Bel Belluz, Nina Moderau, Fotini Poyia, Lee S. Schwartzberg, Neha Tabassum, Jinrui Wen, Jonathan Krell,  and Justin Stebbing
17589-17596
Abstract  |  PDF  |  HTML  |  Order a Reprint

Interactions among variants in TXA2R, P2Y12 and GPIIIa are associated with carotid plaque vulnerability in Chinese population

Interactions among variants in TXA2R, P2Y12 and GPIIIa are associated with carotid plaque vulnerability in Chinese population

https://doi.org/10.18632/oncotarget.24801

Xingyang Yi, Jing Lin, Hua Luo, Ju Zhou, Qiang Zhou, Yanfen Wang,  and Chun Wang
17597-17607
Abstract  |  PDF  |  HTML  |  Order a Reprint

A Jurkat 76 based triple parameter reporter system to evaluate TCR functions and adoptive T cell strategies

A Jurkat 76 based triple parameter reporter system to evaluate TCR functions and adoptive T cell strategies

https://doi.org/10.18632/oncotarget.24807

Sandra Rosskopf, Judith Leitner, Wolfgang Paster, Laura T. Morton, Renate S. Hagedoorn, Peter Steinberger,  and Mirjam H.M. Heemskerk
17608-17619
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Capecitabine reverses tumor escape from anti-VEGF through the eliminating CD11bhigh/Gr1high myeloid cells

Capecitabine reverses tumor escape from anti-VEGF through the eliminating CD11bhigh/Gr1high myeloid cells

https://doi.org/10.18632/oncotarget.24811

Toshiki Iwai, Yui Harada, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara,  and Yoshikazu Yonemitsu
17620-17630
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells

BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells

https://doi.org/10.18632/oncotarget.24815

Erminia Romano, Nicole Rufo, Hannelie Korf, Chantal Mathieu, Abhishek D. Garg,  and Patrizia Agostinis
17631-17644
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells

CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells

https://doi.org/10.18632/oncotarget.24824

Saya Ito, Akihisa Ueno, Takashi Ueda, Hideo Nakagawa, Hidefumi Taniguchi, Naruhiro Kayukawa, Atsuko Fujihara-Iwata, Fumiya Hongo, Koji Okihara,  and Osamu Ukimura
17645-17655
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Enhanced intratumoral expression of RNF2 is a favorable prognostic factor for patients with cutaneous melanoma?

Enhanced intratumoral expression of RNF2 is a favorable prognostic factor for patients with cutaneous melanoma?

https://doi.org/10.18632/oncotarget.24825

Łukasz Kuźbicki, Dariusz Lange, Agata Stanek-Widera, Agnieszka Glińska,  and Barbara W. Chwirot
17656-17663
Abstract  |  PDF  |  HTML  |  Order a Reprint

Efficacy of prophylactic cranial irradiation in patients with limited-disease small-cell lung cancer who were confirmed to have no brain metastasis via magnetic resonance imaging after initial chemoradiotherapy

Efficacy of prophylactic cranial irradiation in patients with limited-disease small-cell lung cancer who were confirmed to have no brain metastasis via magnetic resonance imaging after initial chemoradiotherapy

https://doi.org/10.18632/oncotarget.24830

Nobuaki Mamesaya, Kazushige Wakuda, Katsuhiro Omae, Eriko Miyawaki, Mie Kotake, Takumi Fujiwara, Takahisa Kawamura, Haruki Kobayashi, Kazuhisa Nakashima, Shota Omori, Akira Ono, Hirotsugu Kenmotsu, Tateaki Naito, Haruyasu Murakami, Keita Mori, Hideyuki Harada, Masahiro Endo, Takashi Nakajima,  and Toshiaki Takahashi
17664-17674
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A phase 1 study of lirilumab (antibody against killer immunoglobulin-like receptor antibody KIR2D; IPH2102) in patients with solid tumors and hematologic malignancies

A phase 1 study of lirilumab (antibody against killer immunoglobulin-like receptor antibody KIR2D; IPH2102) in patients with solid tumors and hematologic malignancies

https://doi.org/10.18632/oncotarget.24832

Norbert Vey, Lionel Karlin, Sophie Sadot-Lebouvier, Florence Broussais, Dominique Berton-Rigaud, Jérôme Rey, Aude Charbonnier, Delphine Marie, Pascale André, Carine Paturel, Robert Zerbib, Jaafar Bennouna, Gilles Salles,  and Anthony Gonçalves
17675-17688
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The role of oxidative stress in activity of anticancer thiosemicarbazones

The role of oxidative stress in activity of anticancer thiosemicarbazones

https://doi.org/10.18632/oncotarget.24844

Katarzyna Malarz, Anna Mrozek-Wilczkiewicz, Maciej Serda, Marta Rejmund, Jaroslaw Polanski,  and Robert Musiol
17689-17710
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PIK3CA mutation, reduced AKT serine 473 phosphorylation, and increased ERα serine 167 phosphorylation are positive prognostic indicators in postmenopausal estrogen receptor-positive early breast cancer

PIK3CA mutation, reduced AKT serine 473 phosphorylation, and increased ERα serine 167 phosphorylation are positive prognostic indicators in postmenopausal estrogen receptor-positive early breast cancer

https://doi.org/10.18632/oncotarget.24845

Naoko Ishida, Motoi Baba, Yutaka Hatanaka, Kanako Hagio, Hiromi Okada, Kanako C. Hatanaka, Kenichi Togashi, Yoshihiro Matsuno,  and Hiroko Yamashita
17711-17724
Abstract  |  PDF  |  HTML  |  Order a Reprint

The secondary prevention of stroke according to cytochrome P450 2C19 genotype in patients with acute large-artery atherosclerosis stroke

The secondary prevention of stroke according to cytochrome P450 2C19 genotype in patients with acute large-artery atherosclerosis stroke

https://doi.org/10.18632/oncotarget.24877

Xingyang Yi, Jing Lin, Ju Zhou, Yanfeng Wang, Ruyue Huang,  and Chun Wang
17725-17734
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical importance of the EMSY gene expression and polymorphisms in ovarian cancer

Clinical importance of the EMSY gene expression and polymorphisms in ovarian cancer

https://doi.org/10.18632/oncotarget.24878

Agnieszka Dansonka-Mieszkowska, Lukasz M. Szafron, Joanna Moes-Sosnowska, Mariusz Kulinczak, Anna Balcerak, Bozena Konopka, Magdalena Kulesza, Agnieszka Budzilowska, Martyna Lukasik, Urszula Piekarska, Iwona K. Rzepecka, Joanna Parada, Renata Zub, Barbara Pienkowska-Grela, Radoslaw Madry, Jan K. Siwicki,  and Jolanta Kupryjanczyk
17735-17755
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating tumor DNA in early response assessment and monitoring of advanced colorectal cancer treated with a multi-kinase inhibitor

Circulating tumor DNA in early response assessment and monitoring of advanced colorectal cancer treated with a multi-kinase inhibitor

https://doi.org/10.18632/oncotarget.24879

Caroline Vandeputte, Pashalina Kehagias, Hakim El Housni, Lieveke Ameye, Jean-François Laes, Christine Desmedt, Christos Sotiriou, Amélie Deleporte, Francesco Puleo, Karen Geboes, Thierry Delaunoit, Gauthier Demolin, Marc Peeters, Lionel D’Hondt, Jos Janssens, Javier Carrasco, Raphaël Marechal, Maria Gomez Galdon, Pierre Heimann, Marianne Paesmans, Patrick Flamen,  and Alain Hendlisz
17756-17769
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aloe-emodin as drug candidate for cancer therapy

Aloe-emodin as drug candidate for cancer therapy

https://doi.org/10.18632/oncotarget.24880

Nadire Özenver, Mohamed Saeed, Lütfiye Ömür Demirezer,  and Thomas Efferth
17770-17796
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Molecular responses to therapeutic proteasome inhibitors in multiple myeloma patients are donor-, cell type- and drug-dependent

Molecular responses to therapeutic proteasome inhibitors in multiple myeloma patients are donor-, cell type- and drug-dependent

https://doi.org/10.18632/oncotarget.24882

Eleni-Dimitra Papanagnou, Evangelos Terpos, Efstathios Kastritis, Issidora S. Papassideri, Ourania E. Tsitsilonis, Meletios A. Dimopoulos,  and Ioannis P. Trougakos
17797-17809
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dual antiplatelet therapy with clopidogrel and aspirin increases mortality in 4T1 metastatic breast cancer-bearing mice by inducing vascular mimicry in primary tumour

Dual antiplatelet therapy with clopidogrel and aspirin increases mortality in 4T1 metastatic breast cancer-bearing mice by inducing vascular mimicry in primary tumour

https://doi.org/10.18632/oncotarget.24891

Marta Smeda, Anna Kieronska, Bartosz Proniewski, Agnieszka Jasztal, Anna Selmi, Krystyna Wandzel, Agnieszka Zakrzewska, Tomasz Wojcik, Kamil Przyborowski, Katarzyna Derszniak, Marta Stojak, Dawid Kaczor, Elzbieta Buczek, Cezary Watala, Joanna Wietrzyk,  and Stefan Chlopicki
17810-17824
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Let-7b inhibits cancer-promoting effects of breast cancer-associated fibroblasts through IL-8 repression

Let-7b inhibits cancer-promoting effects of breast cancer-associated fibroblasts through IL-8 repression

https://doi.org/10.18632/oncotarget.24895

Bothina Al-Harbi, Siti-Fauziah Hendrayani, Gabriela Silva,  and Abdelilah Aboussekhra
17825-17838
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Structural characterization and in vivo pro-tumor properties of a highly conserved matrikine

Structural characterization and in vivo pro-tumor properties of a highly conserved matrikine

https://doi.org/10.18632/oncotarget.24894

Jordan Da silva, Pedro Lameiras, Abdelilah Beljebbar, Alexandre Berquand, Matthieu Villemin, Laurent Ramont, Sylvain Dukic, Jean-Marc Nuzillard, Michael Molinari, Mathieu Gautier, Sylvie Brassart-Pasco,  and Bertrand Brassart
17839-17857
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High levels of circulating endothelial progenitor cells in patients with diabetic retinopathy are positively associated with ARHGAP22 expression

High levels of circulating endothelial progenitor cells in patients with diabetic retinopathy are positively associated with ARHGAP22 expression

https://doi.org/10.18632/oncotarget.24909

Yu-Chuen Huang, Wen-Ling Liao, Jane-Ming Lin, Ching-Chu Chen, Shih-Ping Liu, Shih-Yin Chen, Yu-Ning Lin, Yu-Jie Lei, Huan-Ting Liu, Yu-Jen Chen,  and Fuu-Jen Tsai
17858-17866
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Advance care planning and outcome in pediatric palliative home care

Advance care planning and outcome in pediatric palliative home care

https://doi.org/10.18632/oncotarget.24929

Jessica I. Hoell, Hannah L. Weber, Stefan Balzer, Mareike Danneberg, Gabriele Gagnon, Laura Trocan, Arndt Borkhardt, Gisela Janßen,  and Michaela Kuhlen
17867-17875
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Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types

Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types

https://doi.org/10.18632/oncotarget.24947

Prashant D. Tailor, Sai Karthik Kodeboyina, Shan Bai, Nikhil Patel, Shruti Sharma, Akshay Ratnani, John A. Copland, Jin-Xiong She,  and Ashok Sharma
17876-17888
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Similar expression profiles in CD34+ cells from chronic phase chronic myeloid leukemia patients with and without deep molecular responses to nilotinib

Similar expression profiles in CD34+ cells from chronic phase chronic myeloid leukemia patients with and without deep molecular responses to nilotinib

https://doi.org/10.18632/oncotarget.24954

Ami B. Patel, Thoralf Lange, Anthony D. Pomicter, Christopher J. Conley, Christina A. Harrington, Kimberly R. Reynolds, Todd W. Kelley, Thomas O’Hare,  and Michael W. Deininger
17889-17894
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tissue miRNA 483-3p expression predicts tumor recurrence after surgical resection in histologically advanced hepatocellular carcinomas

Tissue miRNA 483-3p expression predicts tumor recurrence after surgical resection in histologically advanced hepatocellular carcinomas

https://doi.org/10.18632/oncotarget.24860

Francesco Vasuri, Silvia Fittipaldi, Vanessa De Pace, Laura Gramantieri, Valentina Bertuzzo, Matteo Cescon, Antonio D. Pinna, Michelangelo Fiorentino, Antonia D’Errico,  and Matteo Ravaioli
17895-17905
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Dose-finding study of oxaliplatin associated to capecitabine-based preoperative chemoradiotherapy in locally advanced rectal cancer

Dose-finding study of oxaliplatin associated to capecitabine-based preoperative chemoradiotherapy in locally advanced rectal cancer

https://doi.org/10.18632/oncotarget.24665

Gemma Bruera, Mario Di Staso, Pierluigi Bonfili, Antonio Galvano, Rosa Manetta, Gino Coletti, Roberto Vicentini, Stefano Guadagni, Corrado Ficorella, Ernesto Di Cesare, Antonio Russo,  and Enrico Ricevuto
17906-17914
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Reviews

Microbiota effects on cancer: from risks to therapies

Microbiota effects on cancer: from risks to therapies

https://doi.org/10.18632/oncotarget.24681

Domenica Rea, Giovanni Coppola, Giuseppe Palma, Antonio Barbieri, Antonio Luciano, Paola Del Prete, Sabrina Rossetti, Massimiliano Berretta, Gaetano Facchini, Sisto Perdonà, Maria Caterina Turco,  and Claudio Arra
17915-17927
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Differential role of CXCR3 in inflammation and colorectal cancer

Differential role of CXCR3 in inflammation and colorectal cancer

https://doi.org/10.18632/oncotarget.24730

Jessicca D. Abron, Narendra P. Singh, Angela E. Murphy, Manoj K. Mishra, Robert L. Price, Mitzi Nagarkatti, Prakash S. Nagarkatti,  and Udai P. Singh
17928-17936
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Phytochemicals as modulators of M1-M2 macrophages in inflammation

Phytochemicals as modulators of M1-M2 macrophages in inflammation

https://doi.org/10.18632/oncotarget.24788

Uzma Saqib, Sutripta Sarkar, Kyoungho Suk, Owais Mohammad, Mirza S. Baig,  and Rajkumar Savai
17937-17950
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Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach

Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach

https://doi.org/10.18632/oncotarget.24885

Katia Mangano, Emanuela Mazzon, Maria Sofia Basile, Roberto Di Marco, Placido Bramanti, Santa Mammana, Maria Cristina Petralia, Paolo Fagone,  and Ferdinando Nicoletti
17951-17970
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Case Reports

Immunotherapy in mucosal melanoma: a case report and review of the literature

Immunotherapy in mucosal melanoma: a case report and review of the literature

https://doi.org/10.18632/oncotarget.24727

Hana Studentova, Hana Kalabova, Pavel Koranda, Karin Chytilova, Ladislava Kucerova, Bohuslav Melichar,  and David Vrana
17971-17977
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Corrections

Correction: Long non-coding RNA HoxA-AS3 interacts with EZH2 to regulate lineage commitment of mesenchymal stem cells

Correction: Long non-coding RNA HoxA-AS3 interacts with EZH2 to regulate lineage commitment of mesenchymal stem cells

https://doi.org/10.18632/oncotarget.25078

Xin-Xing Zhu, Ya-Wei Yan, Demeng Chen, Chun-Zhi Ai, Xifeng Lu, Shan-Shan Xu, Shan Jiang, Gen-Shen Zhong, Dong-Bao Chen,  and Yi-Zhou Jiang
17978-17978
Correction  |  PDF

Correction: A tissue factor-cascade-targeted strategy to tumor vasculature: a combination of EGFP-EGF1 conjugation nanoparticles with photodynamic therapy

Correction: A tissue factor-cascade-targeted strategy to tumor vasculature: a combination of EGFP-EGF1 conjugation nanoparticles with photodynamic therapy

https://doi.org/10.18632/oncotarget.25079

Wei Shi, Yanxue Yin, Yao Wang, Bo Zhang, Pei Tan, Ting Jiang, Heng Mei, Jun Deng, Huafang Wang, Tao Guo, Zhiqing Pang,  and Yu Hu
17979-17979
Correction  |  PDF


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