Oncotarget

Vol 9, No 20

March 16, 2018

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About The Cover

The cover for issue 20 of Oncotarget features Figure 1B, "The diagram showing a general scheme of TAR cloning of a region of interest (in red) from total genomic DNA (in blue) with a linearized TAR vector containing a yeast selectable marker HIS3, centromeric sequence from chromosome 6 (CEN6) and two unique targeting sequences (hook1 and hook2) homologous to 5’ and 3’ ends of the targeted region," from Kouprina, et al.

Table of Contents

Research Papers: Gerotarget (Focus on Aging)

Outcome after neoadjuvant chemotherapy in elderly breast cancer patients – a pooled analysis of individual patient data from eight prospectively randomized controlled trials

Outcome after neoadjuvant chemotherapy in elderly breast cancer patients – a pooled analysis of individual patient data from eight prospectively randomized controlled trials

https://doi.org/10.18632/oncotarget.24586

Gabriel von Waldenfels, Sibylle Loibl, Jenny Furlanetto, Anna Machleidt, Bianca Lederer, Carsten Denkert, Claus Hanusch, Sherko Kümmel, Gunter von Minckwitz, Andreas Schneeweiss, Michael Untch, Kerstin Rhiem, Peter A. Fasching,  and Jens-Uwe Blohmer
15168-15179
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Research Papers

Verification of the methodology for evaluating tumor-infiltrating lymphocytes in colorectal cancer

Verification of the methodology for evaluating tumor-infiltrating lymphocytes in colorectal cancer

https://doi.org/10.18632/oncotarget.24612

Shinji Matsutani, Masatsune Shibutani, Kiyoshi Maeda, Hisashi Nagahara, Tatsunari Fukuoka, Yasuhito Iseki, Kosei Hirakawa,  and Masaichi Ohira
15180-15197
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miR-145 expression enhances integrin expression in SK-GT-4 cell line by down-regulating c-Myc expression

miR-145 expression enhances integrin expression in SK-GT-4 cell line by down-regulating c-Myc expression

https://doi.org/10.18632/oncotarget.24613

Mathieu Francois Derouet, Eugenia Dakpo, Licun Wu, Guan Zehong, James Conner, Shaf Keshavjee, Marc de Perrrot, Thomas Waddell, Elena Elimova, Jonathan Yeung,  and Gail Elizabeth Darling
15198-15207
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RPN2 is effective biomarker to predict the outcome of combined chemotherapy docetaxel and cisplatin for advanced gastric cancer

RPN2 is effective biomarker to predict the outcome of combined chemotherapy docetaxel and cisplatin for advanced gastric cancer

https://doi.org/10.18632/oncotarget.24622

Daisuke Fujimoto, Takanori Goi, Kenji Koneri,  and Yasuo Hirono
15208-15218
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Early hypertension is associated with better clinical outcomes in gastric cancer patients treated with ramucirumab plus paclitaxel

Early hypertension is associated with better clinical outcomes in gastric cancer patients treated with ramucirumab plus paclitaxel

https://doi.org/10.18632/oncotarget.24635

Naoki Fukuda, Daisuke Takahari, Takeru Wakatsuki, Hiroki Osumi, Izuma Nakayama, Tomohiro Matsushima, Takashi Ichimura, Mariko Ogura, Masato Ozaka, Mitsukuni Suenaga, Eiji Shinozaki, Keisho Chin,  and Kensei Yamaguchi
15219-15227
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Reduced expression of α-L-Fucosidase-1 (FUCA-1) predicts recurrence and shorter cancer specific survival in luminal B LN+ breast cancer patients

Reduced expression of α-L-Fucosidase-1 (FUCA-1) predicts recurrence and shorter cancer specific survival in luminal B LN+ breast cancer patients

https://doi.org/10.18632/oncotarget.24445

Serena Bonin, Alessia Parascandolo, Cinzia Aversa, Renzo Barbazza, Nobuo Tsuchida, Maria Domenica Castellone, Giorgio Stanta,  and Giancarlo Vecchio
15228-15238
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The Wnt-β-catenin signaling regulated MRTF-A transcription to activate migration-related genes in human breast cancer cells

The Wnt-β-catenin signaling regulated MRTF-A transcription to activate migration-related genes in human breast cancer cells

https://doi.org/10.18632/oncotarget.23961

Hongpeng He, Fu Du, Yongping He, Zhaoqiang Wei, Chao Meng, Yuexin Xu, Hao Zhou, Nan Wang, Xue-Gang Luo, Wenjian Ma,  and Tong-Cun Zhang
15239-15251
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MEIS-1 level in unresectable hepatocellular carcinoma can predict the post-treatment outcomes of radiofrequency ablation

MEIS-1 level in unresectable hepatocellular carcinoma can predict the post-treatment outcomes of radiofrequency ablation

https://doi.org/10.18632/oncotarget.24165

Hui Xie, Haipeng Yu, Shengtao Tian, Xueling Yang, Ximing Wang, Huaming Wang,  and Zhi Guo
15252-15265
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PIK3CA and KRAS mutations in cell free circulating DNA are useful markers for monitoring ovarian clear cell carcinoma

PIK3CA and KRAS mutations in cell free circulating DNA are useful markers for monitoring ovarian clear cell carcinoma

https://doi.org/10.18632/oncotarget.24555

Asuka Morikawa, Tomoatsu Hayashi, Naomi Shimizu, Mana Kobayashi, Kenzui Taniue, Akiko Takahashi, Kota Tachibana, Misato Saito, Ayako Kawabata, Yasushi Iida, Kazu Ueda, Motoaki Saito, Nozomu Yanaihara, Hiroshi Tanabe, Kyosuke Yamada, Hirokuni Takano, Osamu Nureki, Aikou Okamoto,  and Tetsu Akiyama
15266-15274
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Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient

Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient

https://doi.org/10.18632/oncotarget.24567

Natalay Kouprina, Mikhail Liskovykh, Nicholas C.O. Lee, Vladimir N. Noskov, Joshua J. Waterfall, Robert L. Walker, Paul S. Meltzer, Eric J. Topol,  and Vladimir Larionov
15275-15291
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Pomalidomide promotes chemosensitization of pancreatic cancer by inhibition of NF-κB

Pomalidomide promotes chemosensitization of pancreatic cancer by inhibition of NF-κB

https://doi.org/10.18632/oncotarget.24577

Yoshihiro Shirai, Nobuhiro Saito, Tadashi Uwagawa, Hiroaki Shiba, Takashi Horiuchi, Ryota Iwase, Koichiro Haruki, Toya Ohashi,  and Katsuhiko Yanaga
15292-15301
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Differential clinicopathological and molecular features within late-onset colorectal cancer according to tumor location

Differential clinicopathological and molecular features within late-onset colorectal cancer according to tumor location

https://doi.org/10.18632/oncotarget.24502

Lorena Brandariz, María Arriba, Juan Luis García, Juana María Cano, Daniel Rueda, Eduardo Rubio, Yolanda Rodríguez, Jessica Pérez, Alfredo Vivas, Carmen Sánchez, Sandra Tapial, Laura Pena, Mariano García-Arranz, Damián García-Olmo, Miguel Urioste, Rogelio González-Sarmiento,  and José Perea
15302-15311
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Stimulation of medulloblastoma stem cells differentiation by a peptidomimetic targeting neuropilin-1

Stimulation of medulloblastoma stem cells differentiation by a peptidomimetic targeting neuropilin-1

https://doi.org/10.18632/oncotarget.24521

Caifeng Gong, Julie Valduga, Alicia Chateau, Mylène Richard, Nadia Pellgrini-Moïse, Muriel Barberi-Heyob, Pascal Chastagner,  and Cédric Boura
15312-15325
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Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft

Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft

https://doi.org/10.18632/oncotarget.24569

Santosh K. Bharti, Yelena Mironchik, Flonne Wildes, Marie-France Penet, Eibhlin Goggins, Balaji Krishnamachary,  and Zaver M. Bhujwalla
15326-15339
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Outcomes of ALK positive lung cancer patients treated with crizotinib or second-generation ALK inhibitor: a monoinstitutional experience

Outcomes of ALK positive lung cancer patients treated with crizotinib or second-generation ALK inhibitor: a monoinstitutional experience

https://doi.org/10.18632/oncotarget.24573

Elisa De Carlo, Maria Chiara Del Savio, Jerry Polesel, Valentina Da Ros, Eleonora Berto, Sandra Santarossa, Emanuela Chimienti, Lucia Fratino,  and Alessandra Bearz
15340-15349
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Circulating miR-106b-3p, miR-101-3p and miR-1246 as diagnostic biomarkers of hepatocellular carcinoma

Circulating miR-106b-3p, miR-101-3p and miR-1246 as diagnostic biomarkers of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.24601

Farzaneh Moshiri, Alessandro Salvi, Laura Gramantieri, Angelo Sangiovanni, Paola Guerriero, Giuseppina De Petro, Cristian Bassi, Laura Lupini, Arash Sattari, Douglas Cheung, Dario Veneziano, Giovanni Nigita, Ram C. Shankaraiah, Nazario Portolani, Paolo Carcoforo, Francesca Fornari, Luigi Bolondi, Antonio Frassoldati, Silvia Sabbioni, Massimo Colombo, Carlo M. Croce,  and Massimo Negrini
15350-15364
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Meta-Analysis

Association between polymorphism rs12722 in COL5A1 and musculoskeletal soft tissue injuries: a systematic review and meta-analysis

Association between polymorphism rs12722 in COL5A1 and musculoskeletal soft tissue injuries: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.23805

Zheng-Tao Lv, Shu-Tao Gao, Peng Cheng, Shuang Liang, Si-Yi Yu, Qing Yang,  and An-Min Chen
15365-15374
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Cancer risks in recipients of renal transplants: a meta-analysis of cohort studies

Cancer risks in recipients of renal transplants: a meta-analysis of cohort studies

https://doi.org/10.18632/oncotarget.23841

Yu Wang, Gong-Bin Lan, Feng-Hua Peng,  and Xu-Biao Xie
15375-15385
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prevalence of human papillomavirus genotypes and relative risk of cervical cancer in China: a systematic review and meta-analysis

Prevalence of human papillomavirus genotypes and relative risk of cervical cancer in China: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.24169

Hui-hui Xu, Kai Wang, Xing-Jun Feng, Shan-shan Dong, Aifen Lin, Ling-Zhi Zheng,  and Wei-hua Yan
15386-15397
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The therapeutic effect of splenectomy plus selective pericardial devascularization versus conventional pericardial devascularization on portal hypertension in China: a meta-analysis

The therapeutic effect of splenectomy plus selective pericardial devascularization versus conventional pericardial devascularization on portal hypertension in China: a meta-analysis

https://doi.org/10.18632/oncotarget.23857

Yajie Zhao,  and Chengfeng Wang
15398-15408
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Clinical Research Papers

Clinical features and management of nonfunctioning giant pituitary adenomas causing hydrocephalus

Clinical features and management of nonfunctioning giant pituitary adenomas causing hydrocephalus

https://doi.org/10.18632/oncotarget.24171

Danfeng Zhang, Jigang Chen, Zhenxing Li, Junyu Wang, Kaiwei Han,  and Lijun Hou
15409-15417
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Reviews

Novel approaches against epidermal growth factor receptor tyrosine kinase inhibitor resistance

Novel approaches against epidermal growth factor receptor tyrosine kinase inhibitor resistance

https://doi.org/10.18632/oncotarget.24624

Carina Heydt, Sebastian Michels, Kenneth S. Thress, Sven Bergner, Jürgen Wolf,  and Reinhard Buettner
15418-15434
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Corrections

Correction: Efficacy of transcatheter arterial chemoembolization for liver metastases arising from pancreatic cancer

Correction: Efficacy of transcatheter arterial chemoembolization for liver metastases arising from pancreatic cancer

https://doi.org/10.18632/oncotarget.24759

Jun-Hui Sun, Tan-Yang Zhou, Yue-Lin Zhang, Guan-Hui Zhou, Chun-Hui Nie, Tong-Yin Zhu, Sheng-Qun Chen, Bao-Quan Wang, Song Ye, Yan Shen, Hua Guo, Wei-Lin Wang,  and Shu-Sen Zheng
15435-15435
Correction  |  PDF

Correction: Post-pancreaticoduodenectomy hemorrhage: DSA diagnosis and endovascular treatment

Correction: Post-pancreaticoduodenectomy hemorrhage: DSA diagnosis and endovascular treatment

https://doi.org/10.18632/oncotarget.24760

Tan-Yang Zhou, Jun-Hui Sun, Yue-Lin Zhang, Guan-Hui Zhou, Chun-Hui Nie, Tong-Yin Zhu, Sheng-Qun Chen, Bao-Quan Wang, Wei-Lin Wang,  and Shu-Sen Zheng
15436-15436
Correction  |  PDF


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