The Oncosearch | Oncotarget

Folic acid supplementation acts as a chemopreventive factor in tumorigenesis of hepatocellular carcinoma by inducing H3K9Me2-dependent transcriptional repression of LCN2 Research Paper

Yin-Ling Zhang, Geng Xue, Hui Miao, Chuan-Chuan Zhou, Shu-Han Sun, Yi Zhang

Published Jul 29, 2019 · Vol. 12, No. 4 · pp. 366-378

Keywords: folic acid, hepatocarcinogenesis, chemoprevention, LCN2, H3K9Me2

Intracellular acting tumor cell-targeted chemotherapy by MSC-suicide gene exosomes Editorial

Cestmir Altaner, Ursula Altanerova, Jana Jakubechova

Published Jul 27, 2019 · Vol. 10, No. 54 · pp. 5573-5575

Keywords: mesenchymal stem/stromal cells, exosome, suicide gene, yCD::UPRT, 5-fluorocytosine, 5-fluorouracil

Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma Research Paper

Omkara Lakshmi Veeranki, Zhimin Tong, Rashmi Dokey, Alicia Mejia, Jianhu Zhang, Yawei Qiao, Pankaj Kumar Singh, Riham Katkhuda, Barbara Mino, Ramesh Tailor, Jaime Rodriguez Canales, Roland Bassett, Jaffer Ajani, Ji Yuan Wu, Scott Kopetz, Mariela Blum, Wayne Hofstetter, Michael Tetzlaff, Sunil Krishnan, Steven H. Lin, Dipen Maru

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4703-4718

Keywords: CDK 9 Inhibitor, esophageal adenocarcinoma, radiation, Axl

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

Mary K. Nesline, Paul DePietro, Grace K. Dy, Amy Early, Antonios Papanicolau-Sengos, Jeffrey M. Conroy, Felicia L. Lenzo, Sean T. Glenn, Hongbin Chen, Anne Grand’Maison, Patrick Boland, Marc S. Ernstoff, Igor Puzanov, Stephen Edge, Stacey Akers, Mateusz Opyrchal, Gurkamal Chatta, Kunle Odunsi, Peter Frederick, Shashikant Lele, Mark Gardner, Carl Morrison

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4616-4629

Keywords: comprehensive genomic profiling, targeted therapy, clinical decision making, next-generation sequencing, real world data

Mutual suppression between BHLHE40/BHLHE41 and the MIR301B-MIR130B cluster is involved in epithelial-to-mesenchymal transition of endometrial cancer cells Research Paper

Kazuo Asanoma, Emiko Hori, Sachiko Yoshida, Hiroshi Yagi, Ichiro Onoyama, Keisuke Kodama, Masafumi Yasunaga, Tatsuhiro Ohgami, Eisuke Kaneki, Kaoru Okugawa, Hideaki Yahata, Kiyoko Kato

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4640-4654

Keywords: microRNA, transcription factor, epithelial-to-mesenchymal transition, cell invasion, endometrial cancer

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Elisabet Frick, Thorkell Gudjonsson, Jorunn Eyfjord, Jon Jonasson, Laufey Tryggvadóttir, Olafur Stefansson, Stefan Sigurdsson

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4664-4678

Keywords: breast cancer, microRNA-190b, DNA methylation, prognosis, estrogen receptor

Mouse models to decipher anti-tumor immunity Editorial

Thomas Parigger, Richard Greil, Nadja Zaborsky

Published Jul 17, 2019 · Vol. 10, No. 49 · pp. 5005-5006

Keywords: CLL mouse model, genetic heterogeneity, clonal evolution, immune oncology

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment Research Paper

Stephen G. Gaffney, Elizabeth B. Perry, Ping-Min Chen, Andrew Greenstein, Susan M. Kaech, Jeffrey P. Townsend

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4532-4545

Keywords: immunotherapy, tumor microenvironment, T lymphocyte, cancer genomics, RNA-seq

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

Laila Babar, Juliann E. Kosovec, Vida Jahangiri, Nobel Chowdhury, Ping Zheng, Ashten N. Omstead, Madison S. Salvitti, Matthew A. Smith, Ajay Goel, Ronan J. Kelly, Blair A. Jobe, Ali H. Zaidi

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4546-4555

Keywords: esophageal adenocarcinoma, LAG3, IDO1, CXCL9, TIM3

Semi-automated analysis of digital whole slides from humanized lung-cancer xenograft models for checkpoint inhibitor response prediction Research Paper

Daniel Bug, Friedrich Feuerhake, Eva Oswald, Julia Schüler, Dorit Merhof

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4587-4597

Keywords: deep learning, digital pathology, histology, non small cell lung cancer, xenograft

EGFR and mTOR as therapeutic targets in glioblastoma Editorial

Michael W. Ronellenfitsch, Anna-Luisa Luger, Joachim P. Steinbach

Published Jul 10, 2019 · Vol. 10, No. 46 · pp. 4721-4723

Keywords: glioblastoma, EGFR, mTOR, DDIT4, tumor microenvironment

Differential gene expression and AKT targeting in triple negative breast cancer Research Paper

Feng-Mao Lin, Susan E. Yost, Wei Wen, Paul H. Frankel, Daniel Schmolze, Pei-Guo Chu, Yate-Ching Yuan, Zheng Liu, John Yim, Zhen Chen, Yuan Yuan

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4356-4368

Keywords: AKT, differential expression, AKT targeting, TNBC

Carbon-ion radiotherapy for cholangiocarcinoma: a multi-institutional study by and the Japan carbon-ion radiation oncology study group (J-CROS) Research Paper

Goro Kasuya, Kazuki Terashima, Kei Shibuya, Shingo Toyama, Daniel K. Ebner, Hiroshi Tsuji, Tomoaki Okimoto, Tatsuya Ohno, Yoshiyuki Shioyama, Takashi Nakano, Tadashi Kamada, the Japan Carbon-Ion Radiation Oncology Study Group

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4369-4379

Keywords: carbon-ion radiotherapy, radiation, cholangiocarcinoma, adverse event, survival

Identification of ZYG11A as a candidate IGF1-dependent proto-oncogene in endometrial cancer Research Paper

Laris Achlaug, Rive Sarfstein, Karthik Nagaraj, Lena Lapkina-Gendler, Ilan Bruchim, Manisha Dixit, Zvi Laron, Shoshana Yakar, Haim Werner

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4437-4448

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor, ZYG11A, p53, endometrial cancer

Paucimannosidic glycoepitopes inhibit tumorigenic processes in glioblastoma multiforme Research Paper

Yvonne Becker, Sarah Förster, Gerrit H. Gielen, Ian Loke, Morten Thaysen-Andersen, Christine Laurini, Kristin Wehrand, Torsten Pietsch, Simone Diestel

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4449-4465

Keywords: cancer progression, glioblastoma multiforme, N-glycosylation, paucimannosidic epitopes, AHNAK

CD90^low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper

Yang Zeng, Binghao Li, Tao Li, Wei Liu, Chongzhao Ran, Richard T. Penson, Mark C. Poznansky, Yanan Du, Huabiao Chen

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4479-4491

Keywords: mesenchymal stem cells, CD90, ovarian cancer, immunotherapy

Tris DBA palladium is an orally available inhibitor of GNAQ mutant uveal melanoma in vivo Research Paper

Elgilda Musi, Gary K. Schwartz, Jae Hyuk Yoo, Shannon J. Odelberg, Dean Y. Li, Michael Y. Bonner, Ponniah Selvakumar, Shikha Rao, Linda C. Gilbert, Justin Elsey, Jack L. Arbiser

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4424-4436

Keywords: melanoma, chemotherapy

Cell-free DNA in newly diagnosed patients with glioblastoma – a clinical prospective feasibility study Research Paper

Dorte Schou Nørøxe, Olga Østrup, Christina Westmose Yde, Lise Barlebo Ahlborn, Finn Cilius Nielsen, Signe Regner Michaelsen, Vibeke Andrée Larsen, Jane Skjøth-Rasmussen, Jannick Brennum, Petra Hamerlik, Hans Skovgaard Poulsen, Ulrik Lassen

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4397-4406

Keywords: glioblastoma, liquid biopsy, cell-free DNA, fragment length, base-pair

Residual disease and immune infiltration as a new surrogate endpoint for TNBC post neoadjuvant chemotherapy Editorial

Stephen L. Luen, Roberto Salgado, Sherene Loi

Published Jul 4, 2019 · Vol. 10, No. 45 · pp. 4612-4614

Keywords: triple negative breast cancer, tumor infiltrating lymphocytes, neoadjuvant chemotherapy, prognosis

Correction: Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget Correction

Ya-Qi Qiu, Cheng-Wei Yang, Yue-Zhi Lee, Ruey-Bing Yang, Chih-Hao Lee, Hsing-Yu Hsu, Chien-Chung Chang, Shiow-Ju Lee

Published Jul 2, 2019 · Vol. 10, No. 47 · pp. 4919-4919

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Folic acid supplementation acts as a chemopreventive factor in tumorigenesis of hepatocellular carcinoma by inducing H3K9Me2-dependent transcriptional repression of LCN2 Research Paper

Intracellular acting tumor cell-targeted chemotherapy by MSC-suicide gene exosomes Editorial

Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma Research Paper

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

Mutual suppression between BHLHE40/BHLHE41 and the MIR301B-MIR130B cluster is involved in epithelial-to-mesenchymal transition of endometrial cancer cells Research Paper

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Mouse models to decipher anti-tumor immunity Editorial

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment Research Paper

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

Semi-automated analysis of digital whole slides from humanized lung-cancer xenograft models for checkpoint inhibitor response prediction Research Paper

EGFR and mTOR as therapeutic targets in glioblastoma Editorial

Differential gene expression and AKT targeting in triple negative breast cancer Research Paper

Carbon-ion radiotherapy for cholangiocarcinoma: a multi-institutional study by and the Japan carbon-ion radiation oncology study group (J-CROS) Research Paper

Identification of ZYG11A as a candidate IGF1-dependent proto-oncogene in endometrial cancer Research Paper

Paucimannosidic glycoepitopes inhibit tumorigenic processes in glioblastoma multiforme Research Paper

CD90^low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper

Tris DBA palladium is an orally available inhibitor of GNAQ mutant uveal melanoma in vivo Research Paper

Cell-free DNA in newly diagnosed patients with glioblastoma – a clinical prospective feasibility study Research Paper

Residual disease and immune infiltration as a new surrogate endpoint for TNBC post neoadjuvant chemotherapy Editorial

Correction: Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Folic acid supplementation acts as a chemopreventive factor in tumorigenesis of hepatocellular carcinoma by inducing H3K9Me2-dependent transcriptional repression of LCN2 Research Paper

Intracellular acting tumor cell-targeted chemotherapy by MSC-suicide gene exosomes Editorial

Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma Research Paper

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

Mutual suppression between BHLHE40/BHLHE41 and the MIR301B-MIR130B cluster is involved in epithelial-to-mesenchymal transition of endometrial cancer cells Research Paper

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Mouse models to decipher anti-tumor immunity Editorial

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment Research Paper

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

Semi-automated analysis of digital whole slides from humanized lung-cancer xenograft models for checkpoint inhibitor response prediction Research Paper

EGFR and mTOR as therapeutic targets in glioblastoma Editorial

Differential gene expression and AKT targeting in triple negative breast cancer Research Paper

Carbon-ion radiotherapy for cholangiocarcinoma: a multi-institutional study by and the Japan carbon-ion radiation oncology study group (J-CROS) Research Paper

Identification of ZYG11A as a candidate IGF1-dependent proto-oncogene in endometrial cancer Research Paper

Paucimannosidic glycoepitopes inhibit tumorigenic processes in glioblastoma multiforme Research Paper

CD90low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper

Tris DBA palladium is an orally available inhibitor of GNAQ mutant uveal melanoma in vivo Research Paper

Cell-free DNA in newly diagnosed patients with glioblastoma – a clinical prospective feasibility study Research Paper

Residual disease and immune infiltration as a new surrogate endpoint for TNBC post neoadjuvant chemotherapy Editorial

Correction: Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget Correction

CD90^low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper