The Oncosearch | Oncotarget

Combatting PDAC with two tumor-targeting small RNAs News

Andrea L. Kasinski

Published Sep 30, 2019 · Vol. 10, No. 57 · pp. 5892-5893

Keywords: PDAC, microRNA, miR-217-5p, KRAS, siRNA

Correction: Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells Correction

Jui-Wen Ma, Chao-Ming Hung, Ying-Chao Lin, Chi-Tang Ho, Jung-Yie Kao, Tzong-Der Way

Published Sep 26, 2019 · Vol. 10, No. 55 · pp. 5727-5729

Correction: Overexpression of CTEN relates to tumor malignant potential and poor outcomes of adenocarcinoma of the esophagogastric junction Correction

Kenichi Aratani, Shuhei Komatsu, Daisuke Ichikawa, Takuma Ohashi, Mahito Miyamae, Wataru Okajima, Taisuke Imamura, Jun Kiuchi, Keiji Nishibeppu, Toshiyuki Kosuga, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Kazuma Okamoto, Hitoshi Tsuda, Eigo Otsuji

Published Sep 26, 2019 · Vol. 10, No. 55 · pp. 5726-5726

Ezrin, more than a metastatic detERMinant? Editorial

Victoria Hoskin, Abdi Ghaffari, Bruce E. Elliott

Published Sep 25, 2019 · Vol. 10, No. 63 · pp. 6755-6757

Keywords: ezrin, metastasis, breast cancer, therapeutic target

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial Research Paper

Rajnish Nagarkar, Darshana Patil, Timothy Crook, Vineet Datta, Sagar Bhalerao, Sonal Dhande, Vijay Palwe, Shirsendu Roy, Prakash Pandit, Ashwini Ghaisas, Raymond Page, Harjeetsingh Kathuria, Ajay Srinivasan, Dadasaheb Akolkar

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5605-5621

Keywords: precision oncology, encyclopedic tumor analysis, personalized cancer treatment, objective response rate, progression free survival

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone Research Paper

Balaji Krishnamachary, Dharmalingam Subramaniam, Prasad Dandawate, Sivapriya Ponnurangam, Pugazhendhi Srinivasan, Prabhu Ramamoorthy, Shahid Umar, Sufi Mary Thomas, Animesh Dhar, Seth Septer, Scott J. Weir, Thomas Attard, Shrikant Anant

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5576-5591

Keywords: Wnt signaling, beta-catenin, natural product, tumor xenograft, preventive agent

Near-infrared fluorescence imaging and photodynamic therapy with indocyanine green lactosomes has antineoplastic effects for gallbladder cancer Research Paper

Hidehiko Hishikawa, Masaki Kaibori, Takumi Tsuda, Kosuke Matsui, Tadayoshi Okumura, Eiichi Ozeki, Kengo Yoshii

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5622-5631

Keywords: near infrared fluorescence imaging, photodynamic therapy, indocyanine green, lactosome, gall bladder cancer

Hyaluronan activated-metabolism phenotype (HAMP) in pancreatic ductal adenocarcinoma Research Paper

Yuzan Kudo, Shiro Kohi, Keiji Hirata, Michael Goggins, Norihiro Sato

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5592-5604

Keywords: hyaluronan, synthesis, degradation, pancreatic cancer, prognosis

Correction: The heparan sulfate mimetic PG545 interferes with Wnt/β-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine Correction

Deok-Beom Jung, Miyong Yun, Eun-Ok Kim, Jaekwang Kim, Bonglee Kim, Ji Hoon Jung, Enfeng Wang, Debabrata Mukhopadhyay, Edward Hammond, Keith Dredge, Viji Shridhar, Sung-Hoon Kim

Published Sep 17, 2019 · Vol. 10, No. 54 · pp. 5669-5669

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

Caitlin D. Lowery, Wayne Blosser, Michele Dowless, Matthew Renschler, Lisa V. Perez, Jennifer Stephens, Bronislaw Pytowski, Heather Wasserstrom, Louis F. Stancato, Beverly Falcon

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5523-5533

Keywords: angiogenesis, pediatric cancer, VEGFR2, ramucirumab, DC101

The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor Research Paper

Jamie M. Aye, Laura L. Stafman, Adele P. Williams, Evan F. Garner, Jerry E. Stewart, Joshua C. Anderson, Smitha Mruthyunjayappa, Mary G. Waldrop, Caroline D. Goolsby, Hooper R. Markert, Colin Quinn, Raoud Marayati, Elizabeth Mroczek-Musulman, Christopher D. Willey, Karina J. Yoon, Kimberly F. Whelan, Elizabeth A. Beierle

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5534-5548

Keywords: kinase inhibition, Wilms tumor

Cathepsin L secretion by host and neoplastic cells potentiates invasion Research Paper

Samantha S. Dykes, Henrietta O. Fasanya, Dietmar W. Siemann

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5560-5568

Keywords: breast cancer, macrophage, invasion, cathepsin L

New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses Research Paper

Aysha AlSahlawi, Rasha Aljelaify, Amna Magrashi, Mariam AlSaeed, Amal Almutairi, Fatimah Alqubaishi, Abdulellah Alturkistani, Abdullah AlObaid, Mohamed Abouelhoda, Latifa AlMubarak, Nada AlTassan, Malak Abedalthagafi

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5549-5559

Keywords: meningioma, FGFR3, NGS, genomics, CNS

Human renal adipose tissue from normal and tumor kidney: its influence on renal cell carcinoma Research Paper

Flavia Alejandra Bruna, Leonardo Rafael Romeo, Fiorella Campo-Verde-Arbocco, David Contador, Silvina Gómez, Flavia Santiano, Corina Verónica Sasso, Leila Zyla, Constanza López-Fontana, Juan Carlos Calvo, Rubén Walter Carón, Virginia Pistone-Creydt

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5454-5467

Keywords: human renal adipose tissue, renal epithelial cells, cancer, epithelial-stromal interactions, migration

Application of C. elegans cancer screening test for the detection of pancreatic tumor in genetically engineered mice Research Paper

Yuji Ueda, Koichi Kawamoto, Masamitsu Konno, Kozo Noguchi, Satoru Kaifuchi, Taroh Satoh, Hidetoshi Eguchi, Yuichiro Doki, Takaaki Hirotsu, Masaki Mori, Hideshi Ishii

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5412-5418

Keywords: early detection, pancreatic cancer, C. elegans, genetically-engineered mice

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Michelle M. Williams, David L. Elion, Bushra Rahman, Donna J. Hicks, Violeta Sanchez, Rebecca S. Cook

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5389-5402

Keywords: Mcl-1, ABT-263 resistance, mTORC1 signaling, luminal breast cancers

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Ming-Bo Huang, Jennifer Y. Wu, James Lillard, Vincent C. Bond

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5419-5438

Keywords: extracellular vesicles, mortalin, complement, SMR peptides, breast cancer

Prognostic and diagnostic role of PSA immunohistochemistry: A tissue microarray study on 21,000 normal and cancerous tissues Research Paper

Sarah Bonk, Martina Kluth, Claudia Hube-Magg, Adam Polonski, Greta Soekeland, Georgia Makropidi-Fraune, Christina Möller-Koop, Melanie Witt, Andreas M. Luebke, Andrea Hinsch, Eike Burandt, Stefan Steurer, Till S. Clauditz, Thorsten Schlomm, Daniel Perez, Markus Graefen, Hans Heinzer, Hartwig Huland, Jakob R. Izbicki, Waldemar Wilczak, Sarah Minner, Guido Sauter, Ronald Simon

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5439-5453

Keywords: prostate specific antigen, specificity, immunohistochemistry, prognosis marker, tissue microarray

One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer Research Paper

Fan Yang, Wenwu Xiao, Yanlei Liu, Ruiwu Liu, Randall Kramer, Xiaocen Li, Yousif Ajena, Christopher M. Baehr, Tatu Rojalin, Hongyong Zhang, Kit S. Lam

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5468-5479

Keywords: oral squamous cancer, α3 integrin, optical imaging, cancer-targeting peptide, orthotopic xenograft model

The role of CD24 in multiple myeloma tumorigenicity and effects of the microenvironment on its expression Research Paper

Nechama Gilad, Hila Zukerman, Marjorie Pick, Moshe E. Gatt

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5480-5491

Keywords: multiple myeloma, CD24, microenvironment, cell cycle and apoptosis changes, tumorigenicity

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Combatting PDAC with two tumor-targeting small RNAs News

Correction: Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells Correction

Correction: Overexpression of CTEN relates to tumor malignant potential and poor outcomes of adenocarcinoma of the esophagogastric junction Correction

Ezrin, more than a metastatic detERMinant? Editorial

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial Research Paper

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone Research Paper

Near-infrared fluorescence imaging and photodynamic therapy with indocyanine green lactosomes has antineoplastic effects for gallbladder cancer Research Paper

Hyaluronan activated-metabolism phenotype (HAMP) in pancreatic ductal adenocarcinoma Research Paper

Correction: The heparan sulfate mimetic PG545 interferes with Wnt/β-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine Correction

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor Research Paper

Cathepsin L secretion by host and neoplastic cells potentiates invasion Research Paper

New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses Research Paper

Human renal adipose tissue from normal and tumor kidney: its influence on renal cell carcinoma Research Paper

Application of C. elegans cancer screening test for the detection of pancreatic tumor in genetically engineered mice Research Paper

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Prognostic and diagnostic role of PSA immunohistochemistry: A tissue microarray study on 21,000 normal and cancerous tissues Research Paper

One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer Research Paper

The role of CD24 in multiple myeloma tumorigenicity and effects of the microenvironment on its expression Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Combatting PDAC with two tumor-targeting small RNAs News

Correction: Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells Correction

Correction: Overexpression of CTEN relates to tumor malignant potential and poor outcomes of adenocarcinoma of the esophagogastric junction Correction

Ezrin, more than a metastatic detERMinant? Editorial

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial Research Paper

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone Research Paper

Near-infrared fluorescence imaging and photodynamic therapy with indocyanine green lactosomes has antineoplastic effects for gallbladder cancer Research Paper

Hyaluronan activated-metabolism phenotype (HAMP) in pancreatic ductal adenocarcinoma Research Paper

Correction: The heparan sulfate mimetic PG545 interferes with Wnt/β-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine Correction

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor Research Paper

Cathepsin L secretion by host and neoplastic cells potentiates invasion Research Paper

New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses Research Paper

Human renal adipose tissue from normal and tumor kidney: its influence on renal cell carcinoma Research Paper

Application of C. elegans cancer screening test for the detection of pancreatic tumor in genetically engineered mice Research Paper

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Prognostic and diagnostic role of PSA immunohistochemistry: A tissue microarray study on 21,000 normal and cancerous tissues Research Paper

One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer Research Paper

The role of CD24 in multiple myeloma tumorigenicity and effects of the microenvironment on its expression Research Paper