The Oncosearch | Oncotarget

Correction: Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Correction

Tiansuo Zhao, He Ren, Li Jia, Jing Chen, Wen Xin, Fan Yan, Jing Li, Xiuchao Wang, Song Gao, Dong Qian, Chongbiao Huang, Jihui Hao

Published Sep 9, 2019 · Vol. 10, No. 53 · pp. 5569-5570

SRC mediates cell cycle regulatory function of Pin1 and is a rational target in treating mucinous ovarian cancer Research Paper

Elisabeth Baron, Shubai Liu, Yuanyuan Hua, Junzheng Yang, Pui-Wah Choi, Wing-Chung Ng, Shu-Kay Ng, Jinyan Du, Charlene C. Ng, Xiao Zhen Zhou, Kun Ping Lu, William R. Welch, Christopher P. Crum, Ross S. Berkowitz, Shu-Wing Ng

Published Sep 3, 2019 · pp. 5724-5736

Keywords: cell cycle regulation, drug sensitivity, ovarian cancer, signal transduction, combination treatment

Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer Research Paper

Maud-Emmanuelle Gilles, Liangliang Hao, Kaelyn Brown, Jihoon Lim, Sangeeta N. Bhatia, Frank J. Slack

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5349-5358

Keywords: miRNAs, KRAS, RNA-based-therapy, PDAC, tumor-penetrating nanocomplexes

A novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylation Research Paper

Henning Karlsson, Wojciech Senkowski, Mårten Fryknäs, Sharmineh Mansoori, Stig Linder, Joachim Gullbo, Rolf Larsson, Peter Nygren

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5372-5382

Keywords: spheroid, tumor model, high-throughput, radiosensitizer, hypoxia

Preliminary observations on soluble programmed cell death protein-1 as a prognostic and predictive biomarker in patients with metastatic melanoma treated with patient-specific autologous vaccines Research Paper

Robert O. Dillman, Gabriel I. Nistor, Bryce T. McLelland, Candace Hsieh, Aleksandra J. Poole, Andrew N. Cornforth, Hans S. Keirstead

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5359-5371

Keywords: programmed cell death protein -1 (PD-1), dendritic cell vaccines, metastatic melanoma

Targeted drug combination therapy design based on driver genes Research Paper

Lilian Zsákai, Anna Sipos, Judit Dobos, Dániel Erős, Csaba Szántai-Kis, Péter Bánhegyi, János Pató, László Őrfi, Zsolt Matula, Gábor Mikala, György Kéri, István Peták, István Vályi-Nagy

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5255-5266

Keywords: combination therapy, cancer driver gene, primary culture, small molecule compound, multiple myeloma

Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: a transcriptome analysis Research Paper

Andrey V. Markov, Alexander E. Kel, Oksana V. Salomatina, Nariman F. Salakhutdinov, Marina A. Zenkova, Evgeniya B. Logashenko

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5267-5297

Keywords: soloxolone methyl, cervical carcinoma, CDDO-Me, cytoscape, mechanism of action

Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells Research Paper

Piyush More, Ute Goedtel-Armbrust, Viral Shah, Marianne Mathaes, Thomas Kindler, Miguel A. Andrade-Navarro, Leszek Wojnowski

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5298-5312

Keywords: topoisomerase II poisons, DNA damage, gene expression, combination therapy, cancer essentiality

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Milos Mihajlovic, Sam Hariri, Koen C.G. Westphal, Manoe J. Janssen, Miriam J. Oost, Laura Bongiovanni, Lambertus P. van den Heuvel, Alain de Bruin, Luuk B. Hilbrands, Rosalinde Masereeuw

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5332-5348

Keywords: bioartificial kidney, cell therapy safety, conditionally immortalized proximal tubule epithelial cells, tumorigenicity, viral integration

Cathepsin L secretion by host and neoplastic cells potentiates invasion Research Paper

Samantha S. Dykes, Henrietta O. Fasanya, Dietmar W. Siemann

Published Aug 27, 2019

Keywords: breast cancer, macrophage, invasion, cathepsin L

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma Research Paper

Jennifer Bryant, Nikolaos Batis, Anna Clara Franke, Gabriella Clancey, Margaret Hartley, Gordon Ryan, Jill Brooks, Andrew D. Southam, Nicholas Barnes, Joanna Parish, Sally Roberts, Farhat Khanim, Rachel Spruce, Hisham Mehanna

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5229-5244

Keywords: head and neck cancer, drug repurposing, drug repositioning, quinacrine, mepacrine

Development and analytical validation of a next-generation sequencing based microsatellite instability (MSI) assay Research Paper

Sarabjot Pabla, Jonathan Andreas, Felicia L. Lenzo, Blake Burgher, Jacob Hagen, Vincent Giamo, Mary K. Nesline, Yirong Wang, Mark Gardner, Jeffrey M. Conroy, Antonios Papanicolau-Sengos, Carl Morrison, Sean T. Glenn

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5181-5193

Keywords: next-generation sequencing, NGS, microsatellite instability, MSI

Ras functional proximity proteomics establishes mTORC2 as new direct ras effector Research Perspective

Joanna R. Kovalski, Ronald L. Shanderson, Paul A. Khavari

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5126-5135

Keywords: Ras, BioID, proteomics, CRISPR, mTORC2

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Takeshi Jimbo, Mana Hatanaka, Takahiro Komatsu, Tomoe Taira, Kentaro Kumazawa, Naoyuki Maeda, Takashi Suzuki, Masahiro Ota, Noriyasu Haginoya, Takeshi Isoyama, Kosaku Fujiwara

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5152-5167

Keywords: AXL, DS-1205, EGFR-TKI resistance, erlotinib, osimertinib

Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma Research Paper

Catrin Tauber, Michael Schultheiss, Raffaele De Luca, Nico Buettner, Sian Llewellyn-Lacey, Florian Emmerich, Sebastian Zehe, David A. Price, Christoph Neumann-Haefelin, Annette Schmitt-Graeff, Maike Hofmann, Robert Thimme

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5194-5206

Keywords: TAA, MAGE-A, HCC, T-cell exhaustion, liver cirrhosis

Urodynamic outcomes after pelvic nerve-sparing radical hysterectomy with or without neoadjuvant chemotherapy Research Paper

Satoshi Tsunetoh, Yoshito Terai, Masaaki Takai, Satoe Fujiwara, Yoshimichi Tanaka, Tomohito Tanaka, Hiroshi Sasaki, Naokazu Ibuki, Takanobu Ubai, Kazuhiro Yamamoto, Haruhito Azuma, Masahide Ohmichi

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5207-5216

Keywords: uterine cervical cancer, nerve-sparing radical hysterectomy (NSRH), urodynamic study, neoadjuvant chemotherapy, balloon-occluded arterial infusion (BOAI)

Increased expression of cathepsin D is required for L1-mediated colon cancer progression Research Paper

Sayon Basu, Sanith Cheriyamundath, Nancy Gavert, Thomas Brabletz, Gal Haase, Avri Ben-Ze’ev

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5217-5228

Keywords: L1, cathepsin D, colon cancer, metastasis, Wnt/β-catenin signaling

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Jennifer Bourn, Sony Pandey, Jashim Uddin, Lawrence Marnett, Maria Cekanova

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5168-5180

Keywords: bladder cancer, TKIs, RTKIs, COX-2, targeted therapies

Correction: Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin’s lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms Correction

Tri Nguyen, Rebecca Parker, Elisa Hawkins, Beata Holkova, Victor Yazbeck, Akhil Kolluri, Maciej Kmieciak, Mohamed Rahmani, Steven Grant

Published Aug 26, 2019 · Vol. 10, No. 51 · pp. 5383-5384

Prognostic value of tumor growth kinetic parameters in prostate cancer patients Research Paper

Gennady M. Zharinov, Oleg A. Bogomolov, Natalia Yu. Neklasova, Grigory A. Raskin, Irina V. Chepurnaya, Sergey N. Bugrov, Vladimir N. Anisimov

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5020-5027

Keywords: prostate cancer, cellular lost factor, Ki-67, prostate specific antigen doubling time, prognostic factors

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Correction: Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Correction

SRC mediates cell cycle regulatory function of Pin1 and is a rational target in treating mucinous ovarian cancer Research Paper

Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer Research Paper

A novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylation Research Paper

Preliminary observations on soluble programmed cell death protein-1 as a prognostic and predictive biomarker in patients with metastatic melanoma treated with patient-specific autologous vaccines Research Paper

Targeted drug combination therapy design based on driver genes Research Paper

Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: a transcriptome analysis Research Paper

Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells Research Paper

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Cathepsin L secretion by host and neoplastic cells potentiates invasion Research Paper

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma Research Paper

Development and analytical validation of a next-generation sequencing based microsatellite instability (MSI) assay Research Paper

Ras functional proximity proteomics establishes mTORC2 as new direct ras effector Research Perspective

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma Research Paper

Urodynamic outcomes after pelvic nerve-sparing radical hysterectomy with or without neoadjuvant chemotherapy Research Paper

Increased expression of cathepsin D is required for L1-mediated colon cancer progression Research Paper

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Correction: Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin’s lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms Correction

Prognostic value of tumor growth kinetic parameters in prostate cancer patients Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Correction: Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Correction

SRC mediates cell cycle regulatory function of Pin1 and is a rational target in treating mucinous ovarian cancer Research Paper

Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer Research Paper

A novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylation Research Paper

Preliminary observations on soluble programmed cell death protein-1 as a prognostic and predictive biomarker in patients with metastatic melanoma treated with patient-specific autologous vaccines Research Paper

Targeted drug combination therapy design based on driver genes Research Paper

Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: a transcriptome analysis Research Paper

Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells Research Paper

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Cathepsin L secretion by host and neoplastic cells potentiates invasion Research Paper

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma Research Paper

Development and analytical validation of a next-generation sequencing based microsatellite instability (MSI) assay Research Paper

Ras functional proximity proteomics establishes mTORC2 as new direct ras effector Research Perspective

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma Research Paper

Urodynamic outcomes after pelvic nerve-sparing radical hysterectomy with or without neoadjuvant chemotherapy Research Paper

Increased expression of cathepsin D is required for L1-mediated colon cancer progression Research Paper

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Correction: Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin’s lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms Correction

Prognostic value of tumor growth kinetic parameters in prostate cancer patients Research Paper