The Oncosearch | Oncotarget

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Richard Glenn C. Delacruz, Imelda T. Sandoval, Kyle Chang, Braden N. Miller, Laura Reyes-Uribe, Ester Borras, Patrick M. Lynch, Melissa W. Taggart, Ernest T. Hawk, Eduardo Vilar, David A. Jones

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3939-3951

Keywords: familial adenomatous polyposis, colon cancer, APC, CNOT3, CtBP1

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis Research Paper

Amit K. Behera, Manoj Kumar, Muthu K. Shanmugam, Aditya Bhattacharya, Vinay J. Rao, Akshay Bhat, Madavan Vasudevan, Kodaganur S. Gopinath, Azeem Mohiyuddin, Anupam Chatterjee, Gautam Sethi, Tapas K. Kundu

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3709-3724

Keywords: oral cancer, oncogene, YY1, CARM1, arginine methylation

PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer Research Paper

Sandeep Rajput, Zhanfang Guo, Shunqiang Li, Cynthia X. Ma

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3667-3680

Keywords: PI3K inhibitor, BKM120, eribulin, triple-negative breast cancer, patient-derived xenograft

Regression of BRAF^V600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report

Peter Y.M. Woo, Tai-Chung Lam, Jenny K.S. Pu, Lai-Fung Li, Roland C.Y. Leung, Jason M.K. Ho, James T.F. Zhung, Belinda Wong, Timonthy S.K. Chan, Herbert H.F. Loong, Ho-Keung Ng

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3818-3826

Keywords: glioblastoma, BRAF^V600E mutation, targeted therapies, BRAF-MEK inhibitors

Cancer-testis antigens MAGEA proteins are incorporated into extracellular vesicles released by cells Research Paper

Anneli Kuldkepp, Magda Karakai, Eve Toomsoo, Olavi Reinsalu, Reet Kurg

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3694-3708

Keywords: cancer-testis antigens, MAGEA, extracellular vesicles, microvesicles

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes Research Paper

Nadin D. Exner, Jaime Alberto Campos Valenzuela, Khalil Abou-El-Ardat, Hrvoje Miletic, Peter C. Huszthy, Petra M. Radehaus, Evelin Schröck, Rolf Bjerkvig, Lars Kaderali, Barbara Klink, Janice M. Nigro

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3641-3653

Keywords: exome sequencing, IDH1, oligodendroglioma, SNV, xenograft

Elevated telomere dysfunction in cells containing the African-centric Pro47Ser cancer-risk variant of TP53 Priority Research Paper

Stephen Tutton, Zhong Deng, Nitish Gulve, Olga Vladimirova, Kate Beishline, Andreas Wiedmer, Maureen Murphy, Paul M. Lieberman

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3581-3591

Keywords: TP53, telomere, TERRA, DNA damage, polymorphism

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

Shan-Ju Yeh, Chien-An Chang, Cheng-Wei Li, Lily Hui-Ching Wang, Bor-Sen Chen

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3760-3806

Keywords: lung adenocarcinoma, lung squamous cell carcinoma, NSCLC, genetic and epigenetic network, potential drug target

Advanced MRI in neuro-oncology: can we proceed without inclusion of energy metabolism? Editorial

Andreas Stadlbauer, Michael Buchfelder, Arnd Dörfler, Stefan Oberndorfer

Published Jun 3, 2019 · Vol. 10, No. 40 · pp. 3994-3995

Keywords: glioblastoma, magnetic resonance imaging, intratumoral heterogeneity, tumor microenvironment, Warburg effect

Cancer vaccines: what’s next? Editorial

Stéphane Depil, Paola Bonaventura, Vincent Alcazer

Published May 28, 2019 · Vol. 10, No. 40 · pp. 3985-3987

Keywords: personalised cancer vaccine, neoepitope, immunotherapy

Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators Research Paper

Gang Cheng, Jacek Zielonka, Micael Hardy, Olivier Ouari, Christopher R. Chitambar, Michael B. Dwinell, Balaraman Kalyanaraman

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3518-3532

Keywords: iron chelators, mitochondria-targeting agents, cancer cell proliferation, biguanide; metformin analogs

In vitro and in vivo anti-tumor effects of brexpiprazole, a newly-developed serotonin-dopamine activity modulator with an improved safety profile Research Paper

Shuhei Suzuki, Masahiro Yamamoto, Keita Togashi, Tomomi Sanomachi, Asuka Sugai, Shizuka Seino, Takashi Yoshioka, Chifumi Kitanaka, Masashi Okada

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3547-3558

Keywords: brexpiprazole, serotonin-dopamine activity modulator, drug repositioning, drug repurposing, survivin

Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas Research Paper

Joshua Loewenstern, John Rutland, Corey Gill, Hanane Arib, Margaret Pain, Melissa Umphlett, Yayoi Kinoshita, Russell McBride, Michael Donovan, Robert Sebra, Joshua Bederson, Mary Fowkes, Raj Shrivastava

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3506-3517

Keywords: meningioma, tumor recurrence, genomics, driver mutation, progression-free survival

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamad Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Mohammed S. Al-Baloshi, Sidgi Syed Anwar Abdo Hasson, Ali Al Jabri, Paul A. McCarron, Murtaza M. Tambuwala

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3472-3490

Keywords: melanoma, frankincense, essential oil, apoptosis, tumor remission

Mesenchymal stem cells confer chemoresistance in breast cancer via a CD9 dependent mechanism Priority Research Paper

Mujib Ullah, Asma Akbar, Nathan Norton Ng, Waldo Concepcion, Avnesh S. Thakor

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3435-3450

Keywords: MSCs, CD9, chemoresistance, cytokine, xenograft tumors

Adaptive responses in a PARP inhibitor window of opportunity trial illustrate limited functional interlesional heterogeneity and potential combination therapy options Research Paper

Marilyne Labrie, Tae-Beom Kim, Zhenlin Ju, Sanghoon Lee, Wei Zhao, Yong Fang, Yiling Lu, Ken Chen, Pedro Ramirez, Michael Frumovitz, Larissa Meyer, Nicole D. Fleming, Anil K. Sood, Robert L. Coleman, Gordon B. Mills, Shannon N. Westin

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3533-3546

Keywords: poly (ADP-ribose) polymerase inhibitor, combination therapy, adaptive response, ovarian cancer, targeted therapy

Targeting IL-6 receptor reduces IgM levels and tumor growth in Waldenström macroglobulinemia Research Paper

Weiguo Han, Stephan J. Matissek, David A. Jackson, Brandon Sklavanitis, Sherine F. Elsawa

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3400-3407

Keywords: Waldenström macroglobulinemia, IL-6, Tocilizumab, tumor microenvironment

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

Kelly M. Bailey, Claire M. Julian, Ariel N. Klinghoffer, Heather Bernard, Peter C. Lucas, Linda M. McAllister-Lucas

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3385-3399

Keywords: EWS-FLI1, Ewing sarcoma, T-cell, interferon, apoptosis

Gene expression profiling as a potential predictor between normal and cancer samples in gastrointestinal carcinoma Research Paper

Panagiotis Apostolou, Aggelos C. Iliopoulos, Panagiotis Parsonidis, Ioannis Papasotiriou

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3328-3338

Keywords: clustering analysis, gastrointestinal cancer, peripheral blood mononuclear cells, qRT-PCR

Temporal characteristics of NF-κB inhibition in blocking bile-induced oncogenic molecular events in hypopharyngeal cells Research Paper

Panagiotis G. Doukas, Dimitra P. Vageli, Sotirios G. Doukas, Clarence T. Sasaki

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3339-3351

Keywords: NF-κB inhibition, STAT3, miR-21, bile reflux, hypopharyngeal cancer

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Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis Research Paper

PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer Research Paper

Regression of BRAF^V600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report

Cancer-testis antigens MAGEA proteins are incorporated into extracellular vesicles released by cells Research Paper

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes Research Paper

Elevated telomere dysfunction in cells containing the African-centric Pro47Ser cancer-risk variant of TP53 Priority Research Paper

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

Advanced MRI in neuro-oncology: can we proceed without inclusion of energy metabolism? Editorial

Cancer vaccines: what’s next? Editorial

Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators Research Paper

In vitro and in vivo anti-tumor effects of brexpiprazole, a newly-developed serotonin-dopamine activity modulator with an improved safety profile Research Paper

Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Mesenchymal stem cells confer chemoresistance in breast cancer via a CD9 dependent mechanism Priority Research Paper

Adaptive responses in a PARP inhibitor window of opportunity trial illustrate limited functional interlesional heterogeneity and potential combination therapy options Research Paper

Targeting IL-6 receptor reduces IgM levels and tumor growth in Waldenström macroglobulinemia Research Paper

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

Gene expression profiling as a potential predictor between normal and cancer samples in gastrointestinal carcinoma Research Paper

Temporal characteristics of NF-κB inhibition in blocking bile-induced oncogenic molecular events in hypopharyngeal cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis Research Paper

PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer Research Paper

Regression of BRAFV600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report

Cancer-testis antigens MAGEA proteins are incorporated into extracellular vesicles released by cells Research Paper

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes Research Paper

Elevated telomere dysfunction in cells containing the African-centric Pro47Ser cancer-risk variant of TP53 Priority Research Paper

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

Advanced MRI in neuro-oncology: can we proceed without inclusion of energy metabolism? Editorial

Cancer vaccines: what’s next? Editorial

Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators Research Paper

In vitro and in vivo anti-tumor effects of brexpiprazole, a newly-developed serotonin-dopamine activity modulator with an improved safety profile Research Paper

Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Mesenchymal stem cells confer chemoresistance in breast cancer via a CD9 dependent mechanism Priority Research Paper

Adaptive responses in a PARP inhibitor window of opportunity trial illustrate limited functional interlesional heterogeneity and potential combination therapy options Research Paper

Targeting IL-6 receptor reduces IgM levels and tumor growth in Waldenström macroglobulinemia Research Paper

EWS-FLI1 low Ewing sarcoma cells demonstrate decreased susceptibility to T-cell-mediated tumor cell apoptosis Research Paper

Gene expression profiling as a potential predictor between normal and cancer samples in gastrointestinal carcinoma Research Paper

Temporal characteristics of NF-κB inhibition in blocking bile-induced oncogenic molecular events in hypopharyngeal cells Research Paper

Regression of BRAF^V600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report