The Oncosearch | Oncotarget

Molecular architecture of the ErbB2 extracellular domain homodimer Research Paper

Shi Hu, Yuna Sun, Yanchun Meng, Xiaoze Wang, Weili Yang, Wenyan Fu, Huaizu Guo, Weizhu Qian, Sheng Hou, Bohua Li, Zihe Rao, Zhiyong Lou, Yajun Guo

Published Jan 30, 2015 · Vol. 6, No. 3 · pp. 1695-1706

Keywords: ErbB2, dimerization, signal transduction, crystal structure, Oncogene

Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis Research Paper

Anne Bruun KrÃ¸igÃ¥rd, Martin Jakob Larsen, Anne-Vibeke LÃ¦nkholm, Ann S. Knoop, Jeanette D. Jensen, Martin Bak, Jan Mollenhauer, Torben A. Kruse, Mads Thomassen

Published Jan 29, 2015 · Vol. 6, No. 8 · pp. 5634-5649

Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer Research Paper

Bo Liu, Leilei Fu, Cui Zhang, Lan Zhang, Yonghui Zhang, Liang Ouyang, Gu He, Jian Huang

Published Jan 27, 2015 · Vol. 6, No. 9 · pp. 6762-6775

Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma Clinical Research Papers

Jeff P. Bruce, Angela B.Y. Hui, Wei Shi, Bayardo Perez-Ordonez, Ilan Weinreb, Wei Xu, Benjamin Haibe-Kains, Daryl M. Waggott, Paul C. Boutros, Brian Oâ€™Sullivan, John Waldron, Shao Hui Huang, Eric X. Chen, Ralph Gilbert, Fei-Fei Liu

Published Jan 23, 2015 · Vol. 6, No. 6 · pp. 4537-4550

The microRNA feedback regulation of p63 in cancer progression Review

Changwei Lin, Xiaorong Li, Yi Zhang, Yihang Guo, Jianyu Zhou, Kai Gao, Jing Dai, Gui Hu, Lv Lv, Juan Du, Yi Zhang

Published Jan 23, 2015 · Vol. 6, No. 11 · pp. 8434-8453

Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease Priority Research Paper

Rebecca Lamb, Bela Ozsvari, Camilla L. Lisanti, Herbert B. Tanowitz, Anthony Howell, Ubaldo E. Martinez-Outschoorn, Federica Sotgia, Michael P. Lisanti

Published Jan 22, 2015 · Vol. 6, No. 7 · pp. 4569-4584

MicroRNA regulation of molecular pathways as a generic mechanism and as a core disease phenotype Research Paper

Rotem Ben-Hamo, Sol Efroni

Published Jan 22, 2015 · Vol. 6, No. 3 · pp. 1594-1604

Keywords: microRNA, Signaling pathways, Cancer, Phenotype, Regulation

Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma Research Paper

Sang-Hyun Lee, In Cheul Jeung, Tae Woo Park, Kyungmin Lee, Dong Gwang Lee, Young-Lai Cho, Tae Sup Lee, Hee-Jun Na, Young-Jun Park, Hee Gu Lee, Mun Sik Jeong, Kwang-Hee Bae, Sang Chul Lee, Hyo Jin Lee, Young-Guen Kwon, Hyo Jeong Hong, Jang-Seong Kim, Jeong-Ki Min

Published Jan 22, 2015 · Vol. 6, No. 9 · pp. 7182-7194

Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer Research Paper

Wing-yin Leung, Ioannis Roxanis, Helen Sheldon, Francesca M. Buffa, Ji-Liang Li, Adrian L. Harris, Anthony Kong

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5678-5694

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma Research Paper

Lifang Yang, Liyu Liu, Zhijie Xu, Weihua Liao, Deyun Feng, Xin Dong, San Xu, Lanbo Xiao, Jingchen Lu, Xiangjian Luo, Min Tang, Ann M. Bode, Zigang Dong, Lunquan Sun, Ya Cao

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5804-5817

Vacuolar ATPase 'a2' isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancer Research Paper

Arpita Kulshrestha, Gajendra K. Katara, Safaa Ibrahim, Sahithi Pamarthy, Mukesh K. Jaiswal, Alice Gilman Sachs, Kenneth D. Beaman

Published Jan 21, 2015 · Vol. 6, No. 6 · pp. 3797-3810

Keywords: Vacuolar ATPase, a2 isoform, ovarian cancer, invasion, cortactin, MMP

NF-kB signaling mediates acquired resistance after PARP inhibition Research Paper

Yuko Nakagawa, Anna S Sedukhina, Naoki Okamoto, Satoi Nagasawa, Nao Suzuki, Tomohiko Ohta, Hiroyoshi Hattori, Marta Roche-Molina, Ana J NarvÃ¡ez, Anand D Jeyasekharan, Juan A Bernal, Ko Sato

Published Jan 12, 2015 · Vol. 6, No. 6 · pp. 3825-3839

miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway Research Paper

Xinsen Xu, Wei Chen, Runchen Miao, Yanyan Zhou, Zhixin Wang, Lingqiang Zhang, Yong Wan, Yafeng Dong, Kai Qu, Chang Liu

Published Jan 9, 2015 · Vol. 6, No. 6 · pp. 3988-4004

ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer Research Paper

Min Ho Choe, Joong Won Min, Hong Bae Jeon, Dong-Hyung Cho, Jeong Su Oh, Hyun Gyu Lee, Sang-Gu Hwang, Sungkwan An, Young-Hoon Han, Jae-Sung Kim

Published Jan 8, 2015 · Vol. 6, No. 5 · pp. 2654-2666

Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapy Research Paper

Hui Zhao, Claire M. Faltermeier, Lori Mendelsohn, Peggy L. Porter, Bruce E. Clurman, James M. Roberts

Published Jan 3, 2015 · Vol. 5, No. 24 · pp. 12704-12714

Keywords: p27Kip1 (p27), cell proliferation, cytoplasmic localization, Her2+ breast cancer cells, lapatinib, drug sensitivity

Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers Research Paper

Libing Xiang, Jiajia Li, Wei Jiang, Xuxia Shen, Wentao Yang, Xiaohua Wu, Huijuan Yang

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4968-4975

Activation of RAS family members confers resistance to ROS1 targeting drugs Research Paper

Marilisa Cargnelutti, Simona Corso, Margherita Pergolizzi, Laurence MÃ©vellec, Dara L. Aisner, Rafal Dziadziuszko, Marileila Varella-Garcia, Paolo M. Comoglio, Robert C. Doebele, Jorge Vialard, Silvia Giordano

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5182-5194

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies Research Paper

Lorenzo Tortolina, David J. Duffy, Massimo Maffei, Nicoletta Castagnino, AimÃ©e M. Carmody, Walter Kolch, Boris N. Kholodenko, Cristina De Ambrosi, Annalisa Barla, Elia M. Biganzoli, Alessio Nencioni, Franco Patrone, Alberto Ballestrero, Gabriele Zoppoli, Alessandro Verri, Silvio Parodi

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5041-5058

Functional consequence of the MET-T1010I polymorphism in breast cancer Priority Research Paper

Shuying Liu, Funda Meric-Bernstam, Napa Parinyanitikul, Bailiang Wang, Agda K. Eterovic, Xiaofeng Zheng, Mihai Gagea, Mariana Chavez-MacGregor, Naoto T. Ueno, Xiudong Lei, Wanding Zhou, Lakshmy Nair, Debu Tripathy, Powel H. Brown, Gabriel N. Hortobagyi, Ken Chen, John Mendelsohn, Gordon B. Mills, Ana M. Gonzalez-Angulo

Published Dec 31, 2014 · Vol. 6, No. 5 · pp. 2604-2614

Activating enhancer-binding protein-2Î± induces cyclooxygenase-2 expression and promotes nasopharyngeal carcinoma growth Research Paper

Dingbo Shi, Xiangsheng Xiao, Yun Tian, Lijun Qin, Fangyun Xie, Rui Sun, Jingshu Wang, Wenbin Li, Tianze Liu, Yao Xiao, Wendan Yu, Wei Guo, Yuqing Xiong, Huijuan Qiu, Tiebang Kang, Wenlin Huang, Chong Zhao, Wuguo Deng

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5005-5021

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Molecular architecture of the ErbB2 extracellular domain homodimer Research Paper

Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis Research Paper

Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer Research Paper

Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma Clinical Research Papers

The microRNA feedback regulation of p63 in cancer progression Review

Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease Priority Research Paper

MicroRNA regulation of molecular pathways as a generic mechanism and as a core disease phenotype Research Paper

Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma Research Paper

Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer Research Paper

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma Research Paper

Vacuolar ATPase 'a2' isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancer Research Paper

NF-kB signaling mediates acquired resistance after PARP inhibition Research Paper

miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway Research Paper

ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer Research Paper

Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapy Research Paper

Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers Research Paper

Activation of RAS family members confers resistance to ROS1 targeting drugs Research Paper

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies Research Paper

Functional consequence of the MET-T1010I polymorphism in breast cancer Priority Research Paper

Activating enhancer-binding protein-2Î± induces cyclooxygenase-2 expression and promotes nasopharyngeal carcinoma growth Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Molecular architecture of the ErbB2 extracellular domain homodimer Research Paper

Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis Research Paper

Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer Research Paper

Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma Clinical Research Papers

The microRNA feedback regulation of p63 in cancer progression Review

Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease Priority Research Paper

MicroRNA regulation of molecular pathways as a generic mechanism and as a core disease phenotype Research Paper

Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma Research Paper

Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer Research Paper

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma Research Paper

Vacuolar ATPase 'a2' isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancer Research Paper

NF-kB signaling mediates acquired resistance after PARP inhibition Research Paper

miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway Research Paper

ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer Research Paper

Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapy Research Paper

Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers Research Paper

Activation of RAS family members confers resistance to ROS1 targeting drugs Research Paper

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies Research Paper

Functional consequence of the MET-T1010I polymorphism in breast cancer Priority Research Paper

Activating enhancer-binding protein-2Î± induces cyclooxygenase-2 expression and promotes nasopharyngeal carcinoma growth Research Paper