The Oncosearch | Oncotarget

Ku80 cooperates with CBP to promote COX-2 expression and tumor growth Research Paper

Yao Xiao, Jingshu Wang, Yu Qin, Yang Xuan, Yunlu Jia, Wenxian Hu, Wendan Yu, Meng Dai, Zhenglin Li, Canhui Yi, Shilei Zhao, Mei Li, Sha Du, Wei Cheng, Xiangsheng Xiao, Yiming Chen, Taihua Wu, Songshu Meng, Yuhui Yuan, Quentin Liu, Wenlin Huang, Wei Guo, Shusen Wang, Wuguo Deng

Published Mar 8, 2015 · Vol. 6, No. 10 · pp. 8046-8061

Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma Research Paper

Ulrike Graab, Heidi Hahn, Simone Fulda

Published Mar 6, 2015 · Vol. 6, No. 11 · pp. 8722-8735

Keywords: apoptosis, hedgehog, PI3K, rhabdomyosarcoma

A novel cancer immunotherapy based on the combination of a synthetic carbohydrate-pulsed dendritic cell vaccine and glycoengineered cancer cells Research Paper

Lei Qiu, Jie Li, Shichong Yu, Qianli Wang, Yinghua Li, Zhenlin Hu, Qiuye Wu, Zhongwu Guo, Junping Zhang

Published Mar 4, 2015 · Vol. 6, No. 7 · pp. 5195-5203

Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the â€œTHERAPYâ€phase 1-2 trial Clinical Research Papers

Eric Assenat, David Azria, Caroline Mollevi, Rosine Guimbaud, Nicole Tubiana-Mathieu, Denis Smith, Jean-Pierre Delord, Emmanuelle Samalin, Fabienne Portales, Christel Larbouret, Bruno Robert, FrÃ©dÃ©ric Bibeau, Jean-Pierre Bleuse, Evelyne Crapez, Marc Ychou, AndrÃ© PÃ¨legrin

Published Feb 28, 2015 · Vol. 6, No. 14 · pp. 12796-12808

Molecular landscape of pancreatic cancer: implications for current clinical trials Review

Gregory M. Heestand, Razelle Kurzrock

Published Feb 24, 2015 · Vol. 6, No. 7 · pp. 4553-4561

The miR-491-3p/mTORC2/FOXO1 regulatory loop modulates chemo-sensitivity in human tongue cancer Research Paper

Guopei Zheng, Xiaoting Jia, Cong Peng, Yingen Deng, Jiang Yin, Zhijie Zhang, Nan Li, Min Deng, Xiaorong Liu, Hao Liu, Minying Lu, Chengkun Wang, Yixue Gu, Zhimin He

Published Feb 19, 2015 · Vol. 6, No. 9 · pp. 6931-6943

14q32-encoded microRNAs mediate an oligometastatic phenotype Priority Research Paper

Abhineet Uppal, Sean C. Wightman, Stephen Mallon, Go Oshima, Sean P. Pitroda, Qingbei Zhang, Xiaona Huang, Thomas E. Darga, Lei Huang, Jorge Andrade, Huiping Liu, Mark K. Ferguson, Geoffrey L. Greene, Mitchell C. Posner, Samuel Hellman, Nikolai N. Khodarev, Ralph R. Weichselbaum

Published Feb 18, 2015 · Vol. 6, No. 6 · pp. 3540-3552

PD-1 pathway inhibitors: The next generation of immunotherapy for advanced melanoma Review

Jason J. Luke, Patrick A. Ott

Published Feb 17, 2015 · Vol. 6, No. 6 · pp. 3479-3492

Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance? Review

Michelle M. Williams, Rebecca S. Cook

Published Feb 12, 2015 · Vol. 6, No. 6 · pp. 3519-3530

Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma Research Paper

Martin Wartenberg, Inti Zlobec, Aurel Perren, Viktor Hendrik Koelzer, Beat Gloor, Alessandro Lugli, Eva Karamitopoulou

Published Feb 10, 2015 · Vol. 6, No. 6 · pp. 4190-4201

Keywords: FOXP3, CD8, Tumor-associated macrophages, pancreatic cancer, prognosis, immune cell infiltration, epithelial mesenchymal transition, tumor budding, tumor microenvironment

Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction Priority Research Paper

Rebecca Lamb, Hannah Harrison, Duncan L. Smith, Paul A. Townsend, Thomas Jackson, Bela Ozsvari, Ubaldo E. Martinez-Outschoorn, Richard G. Pestell, Anthony Howell, Michael P. Lisanti, Federica Sotgia

Published Feb 10, 2015 · Vol. 6, No. 7 · pp. 4585-4601

MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma Research Paper

Nadiya M. Teplyuk, Erik J. Uhlmann, Andus Hon-Kit Wong, Priya Karmali, Meenakshi Basu, Galina Gabriely, Anant Jain, Yang Wang, E. Antonio Chiocca, Robert Stephens, Eric Marcusson, Ming Yi, Anna M. Krichevsky

Published Feb 6, 2015 · Vol. 6, No. 6 · pp. 3770-3783

ColoLipidGene: signature of lipid metabolism-related genes to predict prognosis in stage-II colon cancer patients Clinical Research Papers

Teodoro Vargas, Juan Moreno-Rubio, JesÃºs Herranz, Paloma Cejas, Susana Molina, Margarita GonzÃ¡lez-Vallinas, Marta Mendiola, Emilio Burgos, Cristina Aguayo, Ana B. Custodio, Isidro Machado, David Ramos, Meritxell Gironella, Isabel Espinosa-Salinas, Ricardo Ramos, Roberto MartÃn-HernÃ¡ndez, Alberto RisueÃ±o, Javier De Las Rivas, Guillermo Reglero, Ricardo Yaya, Carlos FernÃ¡ndez-Martos, Jorge Aparicio, Joan Maurel, Jaime Feliu, Ana RamÃrez de Molina

Published Feb 6, 2015 · Vol. 6, No. 9 · pp. 7348-7363

Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level Research Paper

Jessian L. Munoz, Vivian Rodriguez-Cruz, Shakti H. Ramkissoon, Keith L. Ligon, Steven J. Greco, Pranela Rameshwar

Published Feb 6, 2015 · Vol. 6, No. 2 · pp. 1190-1201

Keywords: glioblastoma, MicroRNA-9, PTCH, Temozolomide, P-gp

Immunohistochemical and genomic profiles of diffuse large B-cell lymphomas: Implications for targeted EZH2 inhibitor therapy? Clinical Research Papers

Sydney Dubois, Sylvain Mareschal, Jean-Michel Picquenot, Pierre-Julien Viailly, Elodie Bohers, Marie Cornic, Philippe Bertrand, Elena Liana Veresezan, Philippe Ruminy, Catherine Maingonnat, Vinciane Marchand, HÃ©lÃ¨ne Lanic, Dominique Penther, Christian Bastard, HervÃ© Tilly, Fabrice Jardin

Published Feb 5, 2015 · Vol. 6, No. 18 · pp. 16712-16724

Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis Research Paper

Li Zhang, Longjiang Shao, Chad J. Creighton, Yiqun Zhang, Li Xin, Michael Ittmann, Jianghua Wang

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6281-6294

Inhibition of Shp2 suppresses mutant EGFR-induced lung tumors in transgenic mouse model of lung adenocarcinoma Research Paper

Valentina E. Schneeberger, Yuan Ren, Noreen Luetteke, Qingling Huang, Liwei Chen, Harshani R. Lawrence, Nicholas J. Lawrence, Eric B. Haura, John M. Koomen, Domenico Coppola, Jie Wu

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6191-6202

Roles of c-Met and RON kinases in tumor progression and their potential as therapeutic targets Review

Katherine Chang, Anand Karnad, Shujie Zhao, James W. Freeman

Published Jan 31, 2015 · Vol. 6, No. 6 · pp. 3507-3518

Coexpression analysis of CD133 and CD44 identifies Proneural and Mesenchymal subtypes of glioblastoma multiforme Research Paper

Daniel V. Brown, Paul M. Daniel, Giovanna M. Dâ€™Abaco, Andrew Gogos, Wayne Ng, Andrew P. Morokoff, Theo Mantamadiotis

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6267-6280

Multiple mechanisms of MYCN dysregulation in Wilms tumour Research Paper

Richard D. Williams, Tasnim Chagtai, Marisa Alcaide-German, John Apps, Jenny Wegert, Sergey Popov, Gordan Vujanic, Harm van Tinteren, Marry M. van den Heuvel-Eibrink, Marcel Kool, Jan de Kraker, David Gisselsson, Norbert Graf, Manfred Gessler, Kathy Pritchard-Jones

Published Jan 31, 2015 · Vol. 6, No. 9 · pp. 7232-7243

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Ku80 cooperates with CBP to promote COX-2 expression and tumor growth Research Paper

Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma Research Paper

A novel cancer immunotherapy based on the combination of a synthetic carbohydrate-pulsed dendritic cell vaccine and glycoengineered cancer cells Research Paper

Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the â€œTHERAPYâ€phase 1-2 trial Clinical Research Papers

Molecular landscape of pancreatic cancer: implications for current clinical trials Review

The miR-491-3p/mTORC2/FOXO1 regulatory loop modulates chemo-sensitivity in human tongue cancer Research Paper

14q32-encoded microRNAs mediate an oligometastatic phenotype Priority Research Paper

PD-1 pathway inhibitors: The next generation of immunotherapy for advanced melanoma Review

Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance? Review

Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma Research Paper

Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction Priority Research Paper

MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma Research Paper

ColoLipidGene: signature of lipid metabolism-related genes to predict prognosis in stage-II colon cancer patients Clinical Research Papers

Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level Research Paper

Immunohistochemical and genomic profiles of diffuse large B-cell lymphomas: Implications for targeted EZH2 inhibitor therapy? Clinical Research Papers

Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis Research Paper

Inhibition of Shp2 suppresses mutant EGFR-induced lung tumors in transgenic mouse model of lung adenocarcinoma Research Paper

Roles of c-Met and RON kinases in tumor progression and their potential as therapeutic targets Review

Coexpression analysis of CD133 and CD44 identifies Proneural and Mesenchymal subtypes of glioblastoma multiforme Research Paper

Multiple mechanisms of MYCN dysregulation in Wilms tumour Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Ku80 cooperates with CBP to promote COX-2 expression and tumor growth Research Paper

Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma Research Paper

A novel cancer immunotherapy based on the combination of a synthetic carbohydrate-pulsed dendritic cell vaccine and glycoengineered cancer cells Research Paper

Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the â€œTHERAPYâ€phase 1-2 trial Clinical Research Papers

Molecular landscape of pancreatic cancer: implications for current clinical trials Review

The miR-491-3p/mTORC2/FOXO1 regulatory loop modulates chemo-sensitivity in human tongue cancer Research Paper

14q32-encoded microRNAs mediate an oligometastatic phenotype Priority Research Paper

PD-1 pathway inhibitors: The next generation of immunotherapy for advanced melanoma Review

Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance? Review

Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma Research Paper

Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction Priority Research Paper

MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma Research Paper

ColoLipidGene: signature of lipid metabolism-related genes to predict prognosis in stage-II colon cancer patients Clinical Research Papers

Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level Research Paper

Immunohistochemical and genomic profiles of diffuse large B-cell lymphomas: Implications for targeted EZH2 inhibitor therapy? Clinical Research Papers

Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis Research Paper

Inhibition of Shp2 suppresses mutant EGFR-induced lung tumors in transgenic mouse model of lung adenocarcinoma Research Paper

Roles of c-Met and RON kinases in tumor progression and their potential as therapeutic targets Review

Coexpression analysis of CD133 and CD44 identifies Proneural and Mesenchymal subtypes of glioblastoma multiforme Research Paper

Multiple mechanisms of MYCN dysregulation in Wilms tumour Research Paper

Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the â€œTHERAPYâ€phase 1-2 trial Clinical Research Papers