The Oncosearch | Oncotarget

Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: identification of a novel p63/Her2/neu expressing subgroup Research Paper

Malathy PV Shekhar, Ikuko Kato, Pratima Nangia-Makker, Larry Tait

Published Feb 24, 2013 · Vol. 4, No. 2 · pp. 231-241

Keywords: breast cancer, p63, Her2/neu, cytokeratin, EGFR

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

Jun-jie Chen, Constantinos M. Mikelis, Yaqin Zhang, J. Silvio Gutkind, Baolin Zhang

Published Feb 23, 2013 · Vol. 4, No. 2 · pp. 206-217

Keywords: oral cancer, TRAIL, death receptors, apoptosis, Ras, oncotarget

HPV16 E5 and KGFR/FGFR2b interplay in differentiating epithelial cells Research Paper

Valeria Purpura, Francesca Belleudi, Silvia Caputo, Maria Rosaria Torrisi

Published Feb 1, 2013 · Vol. 4, No. 2 · pp. 192-205

Keywords: HPV16 E5, FGFR2b, KGFR, differentiation, human keratinocytes

Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans Research Paper

Kyle M. Walsh, Christopher I. Amos, Angela S. Wenzlaff, Ivan P. Gorlov, Jennette D. Sison, Xifeng Wu, Margaret R. Spitz, Helen M. Hansen, Emily Y. Lu, Chongjuan Wei, Huifeng Zhang, Wei Chen, Stacy M. Lloyd, Marsha L. Frazier, Paige M. Bracci, Michael F. Seldin, Margaret R. Wrensch, Ann G. Schwartz, John K. Wiencke

Published Nov 16, 2012 · Vol. 3, No. 11 · pp. 1428-1438

Keywords: Lung cancer, nicotine dependence, African-Americans, genetic association

FAK is a critical regulator of neuroblastoma liver metastasis Research Paper

Sora Lee, Jingbo Qiao, Pritha Paul, Kathleen L. Oâ€™Connor, Mark Evers, Dai H. Chung

Published Nov 16, 2012 · Vol. 3, No. 12 · pp. 1576-1587

Keywords: GRP-R, FAK, malignant transformation, metastasis, neuroblastoma

Targeting HIF2Î± Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma Research Paper

Carole Sourbier, Gaurav Srivastava, Manik C. Ghosh, Sanchari Ghosh, Youfeng Yang, Gopal Gupta, William DeGraff, Murali C. Krishna, James B. Mitchell, Tracey A. Rouault, W. Marston Linehan

Published Nov 8, 2012 · Vol. 3, No. 11 · pp. 1472-1482

Keywords: HIF, Tempol, RCC, VHL, IRP1, iron metabolism

Toll-like receptor 2: therapeutic target for gastric carcinogenesis Editorial

William McCormack, Masanobu Oshima, Patrick Tan, Brendan J. Jenkins

Published Nov 6, 2012 · Vol. 3, No. 11 · pp. 1260-1261

Keywords: TLR2, gastric cancer, anti-apoptosis, cell proliferation, therapy

MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11 Research Paper

Vinayakumar Siragam, Zina Jeyapalan Rutnam, Weining Yang, Ling Fang, Linlin Luo, Xiangling Yan, Minhui Li, Zhaoqun Deng, Jun Qian, Chun Peng, Burton B. Yang

Published Nov 6, 2012 · Vol. 3, No. 11 · pp. 1370-1385

Keywords: microRNA, miR-98, angiogenesis, tumorigenesis, invasion

Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis Research Paper

Katharina Bluemlein, Matthias Glueckmann, Nana-Maria GrÃ¼ning, RenÃ© Feichtinger, Antje KrÃ¼ger, Mirjam MC. Wamelink, Hans Lehrach, Stephen Tate, Daniel Neureiter, Kofler Barbara, Markus Ralser

Published Nov 1, 2012 · Vol. 3, No. 11 · pp. 1356-1369

Keywords: cancer metabolism, pyruvate kinase, proteomics, amino acid profile

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance Review

James Andrew McCubrey, Linda S. Steelman, William H. Chappell, Stephen L. Abrams, Richard A. Franklin, Giuseppe Montalto, Melchiorre Cervello, Massimo Libra, Saverio Candido, Grazia Malaponte, Maria C. Mazzarino, Paolo Fagone, Ferdinando Nicoletti, JÃ¶rg BÃ¤secke, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Michele Milella, Agostino Tafuri, Francesca Chiarini, Camilla Evangelisti, Lucio Cocco, Alberto M. Martelli

Published Oct 20, 2012 · Vol. 3, No. 10 · pp. 1068-1111

Keywords: Targeted Therapy, Therapy Resistance, Cancer Stem Cells, Raf, Akt, PI3K, mTOR

Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response. Review

James Andrew McCubrey, Linda Steeman, William Chappell, Stephen Abrams, Giuseppe Montalto, Melchiorre Cervello, Ferdinando Nicoletti, Paolo Fagone, Grazia Malaponte, Maria Mazzarino, Saverio Candido, Massimo Libra, Jorg Basecke, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Michele Milella, Agostino Tafuri, Lucio Cocco, Camilla Evangelisti, Francesca Chiarini, Alberto Martelli

Published Sep 20, 2012 · Vol. 3, No. 9 · pp. 954-987

Keywords: targeted therapy, therapy resistance, mutations, Raf, Akt, PI3K, mTOR

Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity Review

Gerald J Prud'homme, Yelena Glinka

Published Sep 3, 2012 · Vol. 3, No. 9 · pp. 921-939

Keywords: angiogenesis, cancer stem cell, growth factor, neuropilin, semaphorin, TGF-beta, VEGF

Antagonists of growth hormone-releasing hormone suppress in vivo tumor growth and gene expression in triple negative breast cancers Research Paper

Roberto Perez, Andrew V Schally, Irving Vidaurre, Ricardo Rincon, Norman L Block, Ferenc G Rick

Published Aug 30, 2012 · Vol. 3, No. 9 · pp. 988-997

Keywords: neuropeptide analog, tumor gene expression, receptor silencing, targeted therapy, inflammation

Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma Research Paper

Valentina Bevelacqua, Ylenia Bevelacqua, Saverio Candido, Evangelica Skarmoutsou, Alfredo Amoroso, Claudio Guarneri, Angela Strazzanti, Pietro Gangemi, Maria Clorinda Mazzarino, Fabio D'Amico, James A McCubrey, Massimo Libra, Grazia Malaponte

Published Aug 26, 2012 · Vol. 3, No. 8 · pp. 882-892

Keywords: NECL-5, melanoma, nevus, skin

Mislocalization of death receptors correlates with cellular resistance to their cognate ligands in human breast cancer cells Research Paper

Baolin Zhang, Jun-Jie Chen, Jennifer H.-C. Shen, Leslie Rivera Rosado, Yaqin Zhang, Xu Di

Published Aug 19, 2012 · Vol. 3, No. 8 · pp. 833-842

Keywords: death receptors, cellular localization, breast cancer, targeted cancer therapy, drug resistance

The promise of anti-ErbB3 monoclonals as new cancer therapeutics Review

Luigi Aurisicchio, Emanuele Marra, Giuseppe Roscilli, Rita Mancini, Gennaro Ciliberto

Published Aug 10, 2012 · Vol. 3, No. 8 · pp. 744-758

Keywords: cancer, ErbB3, monoclonal antibodies, mechanism of action, clinical trials

Folate Receptor Alpha: A New Tool in the Diagnosis and Treatment of Lung Cancer Editorial

Laura D. Wood

Published Jul 24, 2012 · Vol. 3, No. 7 · pp. 668-669

Receptor-targeted therapy of human experimental urinary bladder cancers with cytotoxic LH-RH analog AN-152 (AEZS-108) Research Paper

Karoly Szepeshazi, Andrew V Schally, Gunhild Keller, Norman L Block, Daniel Benten, Gabor Halmos, Luca Szalontay, Irving Vidaurre, Miklos Jaszberenyi, Ferenc G Rick

Published Jul 22, 2012 · Vol. 3, No. 7 · pp. 686-699

Keywords: urinary bladder, urothelial cancer, targeted therapy, LH-RH receptor, cytotoxic, doxorubicin

Computer-Based Identification of a Novel LIMK1/2 Inhibitor that Synergizes with Salirasib to Destabilize the Actin Cytoskeleton Research Paper

Efrat Mashiach Farkash, Roni Rak, Galit Elad-Sfadia, Roni Haklai, Shmuel Carmeli, Yoel Kloog, Haim Wolfson

Published Jul 7, 2012 · Vol. 3, No. 6 · pp. 629-639

Keywords: Cofilin, Ras, Rac, Rho, LIMK

FLT3 in lineage specification and plasticity Research Perspective

Sarah Greenblatt, Donald Small

Published May 27, 2012 · Vol. 3, No. 5 · pp. 576-580

Keywords: FLT3, B220, leukemia, lineage, differentiation

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Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: identification of a novel p63/Her2/neu expressing subgroup Research Paper

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

HPV16 E5 and KGFR/FGFR2b interplay in differentiating epithelial cells Research Paper

Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans Research Paper

FAK is a critical regulator of neuroblastoma liver metastasis Research Paper

Targeting HIF2Î± Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma Research Paper

Toll-like receptor 2: therapeutic target for gastric carcinogenesis Editorial

MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11 Research Paper

Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis Research Paper

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance Review

Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response. Review

Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity Review

Antagonists of growth hormone-releasing hormone suppress in vivo tumor growth and gene expression in triple negative breast cancers Research Paper

Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma Research Paper

Mislocalization of death receptors correlates with cellular resistance to their cognate ligands in human breast cancer cells Research Paper

The promise of anti-ErbB3 monoclonals as new cancer therapeutics Review

Folate Receptor Alpha: A New Tool in the Diagnosis and Treatment of Lung Cancer Editorial

Receptor-targeted therapy of human experimental urinary bladder cancers with cytotoxic LH-RH analog AN-152 (AEZS-108) Research Paper

Computer-Based Identification of a Novel LIMK1/2 Inhibitor that Synergizes with Salirasib to Destabilize the Actin Cytoskeleton Research Paper

FLT3 in lineage specification and plasticity Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: identification of a novel p63/Her2/neu expressing subgroup Research Paper

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

HPV16 E5 and KGFR/FGFR2b interplay in differentiating epithelial cells Research Paper

Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans Research Paper

FAK is a critical regulator of neuroblastoma liver metastasis Research Paper

Targeting HIF2Î± Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma Research Paper

Toll-like receptor 2: therapeutic target for gastric carcinogenesis Editorial

MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11 Research Paper

Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis Research Paper

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance Review

Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response. Review

Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity Review

Antagonists of growth hormone-releasing hormone suppress in vivo tumor growth and gene expression in triple negative breast cancers Research Paper

Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma Research Paper

Mislocalization of death receptors correlates with cellular resistance to their cognate ligands in human breast cancer cells Research Paper

The promise of anti-ErbB3 monoclonals as new cancer therapeutics Review

Folate Receptor Alpha: A New Tool in the Diagnosis and Treatment of Lung Cancer Editorial

Receptor-targeted therapy of human experimental urinary bladder cancers with cytotoxic LH-RH analog AN-152 (AEZS-108) Research Paper

Computer-Based Identification of a Novel LIMK1/2 Inhibitor that Synergizes with Salirasib to Destabilize the Actin Cytoskeleton Research Paper

FLT3 in lineage specification and plasticity Research Perspective