The Oncosearch | Oncotarget

Targeting Aerobic Glycolysis and HIF-1Î± Expression Enhance Imiquimod-induced Apoptosis in Cancer Cells Research Paper

Shi-Wei Huang, Jun-Kai Kao, Chun-Ying Wu, Sin-Ting Wang, Hsin-Chen Lee, Shu-Mei Liang, Yi-Ju Chen, Jeng-Jer Shieh

Published Mar 12, 2014 · Vol. 5, No. 5 · pp. 1363-1381

Keywords: imiquimod, aerobic glycolysis, HIF-1alpha, ï€¬ï€ apoptosis

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style Research Paper

Francesca Margheri, Cristina Luciani, Maria Letizia Taddei, Elisa Giannoni, Anna Laurenzana, Alessio Biagioni, Anastasia ChillÃ, Paola Chiarugi, Gabriella Fibbi, Mario Del Rosso

Published Mar 10, 2014 · Vol. 5, No. 6 · pp. 1538-1553

Keywords: uPAR, mesenchymal movement, amoeboid movement, prostate carcinoma, melanoma

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma Priority Research Paper

Jie Li, Shan Zhu, David Kozono, Kimberly Ng, Diahnn Futalan, Ying Shen, Johnny C. Akers, Tyler Steed, Deepa Kushwaha, Michael Schlabach, Bob S. Carter, Chang-Hyuk Kwon, Frank Furnari, Webster Cavenee, Stephen Elledge, Clark C. Chen

Published Mar 7, 2014 · Vol. 5, No. 4 · pp. 882-893

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy Research Paper

Bo Cao, Yanfeng Qi, Guanyi Zhang, Duo Xu, Yang Zhan, Xavier Alvarez, Zhiyong Guo, Xueqi Fu, Stephen R. Plymate, Oliver Sartor, Haitao Zhang, Yan Dong

Published Mar 4, 2014 · Vol. 5, No. 6 · pp. 1646-1656

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer Research Paper

Da Li, Fang-Fang Bi, Na-Na Chen, Ji-Min Cao, Wu-Ping Sun, Yi-Ming Zhou, Chen Cao, Chun-Yan Li, Qing Yang

Published Feb 27, 2014 · Vol. 5, No. 5 · pp. 1315-1325

Inhibition of HER2-Integrin signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression Research Paper

Parul Gupta, Sanjay K. Srivastava

Published Feb 25, 2014 · Vol. 5, No. 7 · pp. 1812-1828

Keywords: HER2, Breast Cancer, Integrins, Apoptosis, Tumor growth

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

Qiong Wang, Shaoqing Shi, Weiyang He, Mabel T. Padilla, Lin Zhang, Xia Wang, Bin Zhang, Yong Lin

Published Feb 25, 2014 · Vol. 5, No. 5 · pp. 1304-1314

Toll-like receptor-5 agonist Entolimod broadens the therapeutic window of 5-fluorouracil by reducing its toxicity to normal tissues in mice Research Paper

Bojidar M. Kojouharov, Craig M. Brackett, Jean M. Veith, Christopher P. Johnson, Ilya I. Gitlin, Ilia A. Toshkov, Anatoli S. Gleiberman, Andrei V. Gudkov, Lyudmila G. Burdelya

Published Feb 23, 2014 · Vol. 5, No. 3 · pp. 802-814

FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway Research Paper

Janani Ravi, Amita Sneh, Konstantin Shilo, Mohd W. Nasser, Ramesh K. Ganju

Published Feb 21, 2014 · Vol. 5, No. 9 · pp. 2475-2486

Keywords: NSCLC, EGFR, Met-F-AEA, FAAH

Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo Research Paper

Anna Goc, Belal Al-Husein Al-Husein, Katerina Katsanevas, Alison Steinbach, Uvette Lou, Harika Sabbineni, David L. DeRemer, Payaningal R. Somanath

Published Feb 15, 2014 · Vol. 5, No. 3 · pp. 775-787

Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Research Paper

Francesco Crea, Akira Watahiki, Luca Quagliata, Hui Xue, Larissa Pikor, Abhijit Parolia, Yuwei Wang, Dong Lin, Wan L. Lam, William L. Farrar, Takao Isogai, Rudolf Morant, Serenella Castori-Eppenberger, Kim N. Chi, Yuzhuo Wang, Cheryl D. Helgason

Published Feb 6, 2014 · Vol. 5, No. 3 · pp. 764-774

HIF-1Î± downregulation and apoptosis in hypoxic prostate tumor cells infected with oncolytic Mammalian Orthoreovirus Research Paper

Pooja Gupta-Saraf, Cathy L. Miller

Published Jan 31, 2014 · Vol. 5, No. 2 · pp. 561-574

Engineered repressors are potent inhibitors of androgen receptor activity Research Paper

Greg N. Brooke, Sue M. Powell, Derek N. Lavery, Jonathan Waxman, Laki Buluwela, Simak Ali, Charlotte L. Bevan

Published Jan 21, 2014 · Vol. 5, No. 4 · pp. 959-969

Keywords: androgen, prostate cancer, hormone therapy, transcription, AR, MAD, KOX

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Jakob H. Mikkelsen, Zachary T. Resch, Bhanu Kalra, Gopal Savjani, Ajay Kumar, Cheryl A. Conover, Claus Oxvig

Published Jan 17, 2014 · Vol. 5, No. 4 · pp. 1014-1025

Keywords: insulin-like growth factor receptor, pregnancy-associated plasma protein-A, proteolytic inhibition, therapeutic antibody, xenograft mouse model

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

Marcella Salzano, Marta VÃ¡zquez-Cedeira, Marta Sanz-GarcÃa, Alberto Valbuena, Sandra Blanco, Isabel F. FernÃ¡ndez, Pedro A. Lazo

Published Jan 17, 2014 · Vol. 5, No. 7 · pp. 1770-1778

Keywords: Breast cancer, VRK1, Radiation, doxorubicin, chemotherapy, DNA damage, 53BP1

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Ukhyun Jo, Kyong Hwa Park, Young Mi Whang, Jae Sook Sung, Nam Hee Won, Jong Kuk Park, Yeul Hong Kim

Published Jan 16, 2014 · Vol. 5, No. 5 · pp. 1265-1278

Keywords: EGFR, endocytosis, gefitinib, lung cancer, Rab25

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth Research Paper

David Vindrieux, Guillaume Devailly, Arnaud Augert, Benjamin Le Calve, Mylene Ferrand, Pascal Pigny, Lea Payen, Gerard Lambeau, Michael Perrais, Sebastien Aubert, HÃ©lÃ¨ne Simonnet, Robert Dante, David Bernard

Published Jan 16, 2014 · Vol. 5, No. 4 · pp. 1004-1013

Keywords: VHL, MYC, HIF, PLA2R1, tumor suppressor

P-cadherin signals through the laminin receptor Î±6Î²4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells Research Paper

AndrÃ© Filipe Vieira, Ana Sofia Ribeiro, Maria Rita DionÃsio, BÃ¡rbara Sousa, Ana Nobre, AndrÃ© Albergaria, AngÃ©lica Santiago-GÃ³mez, Nuno Mendes, RenÃª Gerhard, Fernando Schmitt, Robert Brian Clarke, Joana Paredes

Published Jan 6, 2014 · Vol. 5, No. 3 · pp. 679-692

Keywords: P-cadherin, Breast cancer, Î±6Î²4 integrin, cancer stem cells, invasion, FAK, Src

The antitumor potential of Interleukin-27 in prostate cancer Research Paper

Emma Di Carlo, Carlo Sorrentino, Alessia Zorzoli, Serena Di Meo, Maria Grazia Tupone, Emanuela Ognio, Gabriella Mincione, Irma Airoldi

Published Dec 28, 2013 · Vol. 5, No. 21 · pp. 10332-10341

Keywords: prostate cancer, interleukin-27, cytokines, immunotherapy, anti-tumor activity, tumor microenvironment

Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN Research Paper

Tian-Huei Chu, Hoi-Hung Chan, Hsiao-Mei Kuo, Li-Fen Liu, Tsung-Hui Hu, Cheuk-Kwan Sun, Mei-Lang Kung, Shih-Wei Lin, E-Ming Wang, Yi-Ling Ma, Kwan-Hung Cheng, Kwok-Hung Lai, Zhi-Hong Wen, Ping-I Hsu, Ming-Hong Tai

Published Dec 28, 2013 · Vol. 5, No. 6 · pp. 1475-1490

Keywords: hepatocellular carcinoma, hepatic cancer stem cells, celecoxib, prostaglandin E2, phosphatase and tensin homolog

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Targeting Aerobic Glycolysis and HIF-1Î± Expression Enhance Imiquimod-induced Apoptosis in Cancer Cells Research Paper

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style Research Paper

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma Priority Research Paper

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy Research Paper

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer Research Paper

Inhibition of HER2-Integrin signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression Research Paper

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

Toll-like receptor-5 agonist Entolimod broadens the therapeutic window of 5-fluorouracil by reducing its toxicity to normal tissues in mice Research Paper

FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway Research Paper

Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo Research Paper

Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Research Paper

HIF-1Î± downregulation and apoptosis in hypoxic prostate tumor cells infected with oncolytic Mammalian Orthoreovirus Research Paper

Engineered repressors are potent inhibitors of androgen receptor activity Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth Research Paper

P-cadherin signals through the laminin receptor Î±6Î²4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells Research Paper

The antitumor potential of Interleukin-27 in prostate cancer Research Paper

Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeting Aerobic Glycolysis and HIF-1Î± Expression Enhance Imiquimod-induced Apoptosis in Cancer Cells Research Paper

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style Research Paper

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma Priority Research Paper

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy Research Paper

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer Research Paper

Inhibition of HER2-Integrin signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression Research Paper

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

Toll-like receptor-5 agonist Entolimod broadens the therapeutic window of 5-fluorouracil by reducing its toxicity to normal tissues in mice Research Paper

FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway Research Paper

Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo Research Paper

Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Research Paper

HIF-1Î± downregulation and apoptosis in hypoxic prostate tumor cells infected with oncolytic Mammalian Orthoreovirus Research Paper

Engineered repressors are potent inhibitors of androgen receptor activity Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth Research Paper

P-cadherin signals through the laminin receptor Î±6Î²4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells Research Paper

The antitumor potential of Interleukin-27 in prostate cancer Research Paper

Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN Research Paper