The Oncosearch | Oncotarget

AID-induced remodeling of immunoglobulin genes and B cell fate Review

Brice Laffleur, Nicolas Denis-Lagache, Sophie PÃ©ron, Christophe Sirac, Jeanne Moreau, Michel CognÃ©

Published Dec 14, 2013 · Vol. 5, No. 5 · pp. 1118-1131

Keywords: AID, B cell fate, BCR, immunoglobulin genes

The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model Brief Reports

Sebastian Kobold, Melanie Merk, Luisa Hofer, Philip Peters, Richard Bucala, Stefan Endres

Published Dec 12, 2013 · Vol. 5, No. 1 · pp. 103-107

Keywords: Cytokine, MIF, cancer, apoptosis

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

Christine B. Ambrosone, Allyson C. Young, Lara E. Sucheston, Dan Wang, Li Yan, Song Liu, Li Tang, Qiang Hu, Jo L. Freudenheim, Peter G. Shields, Carl D. Morrison, Kitaw Demissie, Michael J. Higgins

Published Nov 29, 2013 · Vol. 5, No. 1 · pp. 237-248

Keywords: DNA methylation, breast cancer, disparities, estrogen receptor, African-American, genome-wide

A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1 Research Paper

LucÃa Cabal-Hierro, Noelia Artime, JuliÃ¡n Iglesias, Miguel A. Prado, Lorea Ugarte-Gil, Pedro Casado, BelÃ©n FernÃ¡ndez-GarcÃa, Bryant G. Darnay, Pedro S. Lazo

Published Nov 29, 2013 · Vol. 5, No. 1 · pp. 224-236

Keywords: TNF receptors, Death Receptors, TRAF2, Apoptosis, NF-kappaB

Hypoxia shifts activity of neuropeptide Y in Ewing sarcoma from growth-inhibitory to growth-promoting effects Research Paper

Jason U. Tilan, Congyi Lu, Susana Galli, Ewa Izycka-Swieszewska, Joshua P. Earnest, Asim Shabbir, Lindsay M. Everhart, Shuo Wang, Samantha Martin, Meredith Horton, Akanksha Mahajan, David Christian, Alison O'Neill, Hongkun Wang, Tingting Zhuang, Magdalena Czarnecka, Michael D. Johnson, Jeffrey A. Toretsky, Joanna B. Kitlinska

Published Nov 26, 2013 · Vol. 4, No. 12 · pp. 2487-2501

Keywords: Neuropeptide Y, Ewing sarcoma, hypoxia, cancer stem cells, angiogenesis

Gefitinib resistance resulted from STAT3-mediated Akt activation in lung cancer cells Research Paper

Kai Wu, Qingshan Chang, Yongju Lu, Ping Qiu, Bailing Chen, Chitra Thakur, Jiaying Sun, Lingzhi Li, Anjaneyulu Kowluru, Fei Chen

Published Nov 24, 2013 · Vol. 4, No. 12 · pp. 2430-2438

Keywords: Gefitinib, EGFR, STAT3, Akt recovery

Chemokines in tumor progression and metastasis Review

Purvaba J. Sarvaiya, Donna Guo, Ilya V. Ulasov, Patrik Gabikian, Maciej S. Lesniak

Published Nov 9, 2013 · Vol. 4, No. 12 · pp. 2171-2185

Keywords: Chemokines, chemokine receptors, cancer, metastasis

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma Research Paper

Jennifer K Wolter, Nikolaus E Wolter, Alvaro Blanch, Teresa Partridge, Lynn Cheng, Daniel A. Morgenstern, Monika Podkowa, David R. Kaplan, Meredith S. Irwin

Published Nov 4, 2013 · Vol. 5, No. 1 · pp. 161-172

Keywords: neuroblastoma, propranolol, beta-adrenergic receptor, p53, p73

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

Kaiming Xu, Lanfang Wang, Hui-Kuo G. Shu

Published Oct 31, 2013 · Vol. 5, No. 5 · pp. 1241-1252

Keywords: glioblastoma, brain tumor, tumorigenesis, cyclooxygenase-2, Id1

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor Research Paper

Russell T Burke, Marc M Loriaux, Kevin S Currie, Scott A Mitchell, Patricia Maciejewski, Astrid S Clarke, Julie A DiPaolo, Brian J Druker, Stephen E Spurgeon, Brian J Lannutti

Published Oct 30, 2013 · Vol. 5, No. 4 · pp. 908-915

Keywords: Chronic Lymphocytic Leukemia, B-cell receptor, signaling pathways, spleen tyrosine kinase, PI3 kinase

ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer Research Paper

Christian Holzmann, Tatiana Kilch, Sven Kappel, Andrea ArmbrÃ¼ster, Volker Jung, Michael StÃ¶ckle, Ivan Bogeski, Eva C Schwarz, Christine Peinelt

Published Oct 28, 2013 · Vol. 4, No. 11 · pp. 2096-2107

Keywords: Membrane androgen receptor, Orai channel, CRAC channel, prostate cancer, Ca2+ signaling

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Jennifer Munkley, Prabhakar Rajan, Nicholas P. Lafferty, Caroline Dalgliesh, Robert M. Jackson, Craig N. Robson, Hing Y. Leung, David J. Elliott

Published Oct 21, 2013 · Vol. 5, No. 1 · pp. 131-139

Keywords: TSC2, mTOR, mRNA isoform, androgen, prostate cancer

Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma Research Paper

Hanna Ning, Hiroshi Mitsui, Claire Q.F. Wang, Mayte SuÃ¡rez-FariÃ±as, Juana Gonzalez, Kejal R. Shah, Jie Chen, Israel Coats, Diane Felsen, John A. Carucci, James G. Krueger

Published Oct 2, 2013 · Vol. 4, No. 12 · pp. 2237-2248

Keywords: oncotarget, basal cell carcinoma, anaplastic lymphoma kinase, laser capture microdissection

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Jing Liu, Aimin Xu, Karen Siu-Ling Lam, Nai-Sum Wong, Jie Chen, Peter R R Shepherd, Yu Wang

Published Oct 1, 2013 · Vol. 4, No. 10 · pp. 1804-1818

Keywords: Adiponectin, breast cancer, autophagy, cholesterol, LDLR

The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth Research Paper

Elena Kurenova, Jianqun Liao, Di-Hua He, Darrell Hunt, Michael Yemma, Wiam Bshara, Mukund Seshadri, William G Cance

Published Sep 30, 2013 · Vol. 4, No. 10 · pp. 1632-1646

Keywords: FAK Scaffold Inhibitor, pancreatic cancer, FAK-VEGFR-3 interaction, protein-protein interaction

Combinatorial antitumor effect of HDACs and the PI3K-Akt-mTOR pathway inhibition in a Pten deficient model of prostate cancer Research Paper

Leigh Ellis, ShengYu Ku, Swathi Ramakrishnan, Elena Lasorsa, Gizzou Azabdaftari, Alejandro Godoy, Roberto Pili

Published Sep 27, 2013 · Vol. 4, No. 12 · pp. 2225-2236

Keywords: prostate cancer, BEZ235, panobinostat, DNA damage, ATM, therapy

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

Andrea Treszl, Zita Steiber, Andrew V Schally, Norman L Block, Balazs Dezso, Gabor Olah, Bernadett Rozsa, Klara Fodor, Armin Buglyo, Janos Gardi, Andras Berta, Gabor Halmos

Published Sep 10, 2013 · Vol. 4, No. 10 · pp. 1721-1728

Keywords: uveal melanoma, luteinizing hormone-releasing hormone (LHRH) receptor

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis Research Paper

Daniela Loetsch, Elisabeth Steiner, Klaus Holzmann, Sabine Spiegl-Kreinecker, Christine Pirker, Juraj Hlavaty, Helga Petznek, Balazs Hegedus, Tamas Garay, Thomas Mohr, Wolfgang Sommergruber, Walter Berger, Michael Grusch

Published Sep 1, 2013 · Vol. 4, No. 11 · pp. 1904-1918

Keywords: major vault protein, vault particles, glioblastoma multiforme, EGFR, PI3K, migration, invasion

Isolation and genome-wide expression and methylation characterization of CD31+ cells from normal and malignant human prostate tissue Research Paper

Wei Luo, Hu Qiang, Dan Wang, Kristin K Deeb, Yingyu Ma, Carl D Morrison, Song Liu, Candace S Johnson, Donald L Trump

Published Aug 21, 2013 · Vol. 4, No. 9 · pp. 1472-1483

Keywords: Endothelial cell, Gene expression, DNA methylation, Prostate cancer

Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness Research Paper

Helge Siemens, Rene Jackstadt, Markus Kaller, Heiko Hermeking

Published Aug 6, 2013 · Vol. 4, No. 9 · pp. 1399-1415

Keywords: p53, miR-34, c-Kit, migration, chemoresistance, stemness

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

AID-induced remodeling of immunoglobulin genes and B cell fate Review

The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model Brief Reports

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1 Research Paper

Hypoxia shifts activity of neuropeptide Y in Ewing sarcoma from growth-inhibitory to growth-promoting effects Research Paper

Gefitinib resistance resulted from STAT3-mediated Akt activation in lung cancer cells Research Paper

Chemokines in tumor progression and metastasis Review

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma Research Paper

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor Research Paper

ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer Research Paper

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth Research Paper

Combinatorial antitumor effect of HDACs and the PI3K-Akt-mTOR pathway inhibition in a Pten deficient model of prostate cancer Research Paper

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis Research Paper

Isolation and genome-wide expression and methylation characterization of CD31+ cells from normal and malignant human prostate tissue Research Paper

Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

AID-induced remodeling of immunoglobulin genes and B cell fate Review

The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model Brief Reports

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1 Research Paper

Hypoxia shifts activity of neuropeptide Y in Ewing sarcoma from growth-inhibitory to growth-promoting effects Research Paper

Gefitinib resistance resulted from STAT3-mediated Akt activation in lung cancer cells Research Paper

Chemokines in tumor progression and metastasis Review

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma Research Paper

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor Research Paper

ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer Research Paper

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth Research Paper

Combinatorial antitumor effect of HDACs and the PI3K-Akt-mTOR pathway inhibition in a Pten deficient model of prostate cancer Research Paper

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis Research Paper

Isolation and genome-wide expression and methylation characterization of CD31+ cells from normal and malignant human prostate tissue Research Paper

Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness Research Paper