The Oncosearch | Oncotarget

Novel receptor tyrosine kinase targeted combination therapies for imatinib-resistant gastrointestinal stromal tumors (GIST) Research Paper

Daruka Mahadevan, Noah Theiss, Carla Morales, Amy E. Stejskal, Laurence S. Cooke, Min Zhu, Drew Kurtzman, Rachel Swart, Evan Ong, Wenqing Qi

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 1954-1966

Fibroblast growth factor receptor 1 gene amplification is associated with poor survival in patients with resected esophageal squamous cell carcinoma Clinical Research Papers

Hyo Song Kim, Seung Eun Lee, Yoon Sung Bae, Dae Joon Kim, Changâ€‘Geol Lee, Jin Hur, Hyunsoo Chung, Jun Chul Park, Da Hyun Jung, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee, Hye Ryun Kim, Yong Wha Moon, Joo Hang Kim, Young Mog Shim, Susan S. Jewell, Hyunki Kim, Yoon-La Choi, Byoung Chul Cho

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2562-2572

Targeting of TGF-Î²-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer Research Paper

Hui-Ling Huang, Chi-Hsiang Chiang, Wen-Chun Hung, Ming-Feng Hou

Published Dec 10, 2014 · Vol. 6, No. 2 · pp. 995-1007

Keywords: TGF-Î²-activated protein kinase 1 (TAK1), TAK1 binding proteins (TABs), chemokine (C-C motif) receptor 7 (CCR7), NF-ÎºB, c-JUN, lymphatic invasion

Î³-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1Î±/VEGF pathways under hypoxic condition Research Paper

Heng Xiao, Rongliang Tong, Chaofeng Ding, Zhen Lv, Chengli Du, Chuanhui Peng, Shaobing Cheng, Haiyang Xie, Lin Zhou, Jian Wu, Shusen Zheng

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2180-2192

RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer Research Paper

Ken-ichi Takayama, Takashi Suzuki, Shuichi Tsutsumi, Tetsuya Fujimura, Tomohiko Urano, Satoru Takahashi, Yukio Homma, Hiroyuki Aburatani, Satoshi Inoue

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2263-2276

New insights into the genetics of glioblastoma multiforme by familial exome sequencing Research Paper

Christina Backes, Christian Harz, Ulrike Fischer, Jana Schmitt, Nicole Ludwig, Britt-Sabina Petersen, Sabine C. Mueller, Yoo-Jin Kim, Nadine M. Wolf, Hugo A. Katus, Benjamin Meder, Rhoikos FurtwÃ¤ngler, Andre Franke, Rainer Bohle, Wolfram Henn, Norbert Graf, Andreas Keller, Eckart Meese

Published Dec 10, 2014 · Vol. 6, No. 8 · pp. 5918-5931

NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma Research Paper

Ye Yang, Wen Zhou, Jiliang Xia, Zhimin Gu, Erik Wendlandt, Xin Zhan, Siegfried Janz, Guido Tricot, Fenghuang Zhan

Published Dec 9, 2014 · Vol. 5, No. 23 · pp. 11986-11997

Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe Research Paper

Elodie A. PÃ©rÃ¨s, AurÃ©lie N. GÃ©rault, Samuel Valable, Simon Roussel, JÃ©rÃ´me Toutain, Didier Divoux, Jean-SÃ©bastien Guillamo, Marc Sanson, Myriam Bernaudin, Edwige Petit

Published Dec 3, 2014 · Vol. 6, No. 4 · pp. 2101-2119

Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFÎ± and ROS production Research Paper

Xinfang Yu, Qipan Deng, Wei Li, Lanbo Xiao, Xiangjian Luo, Xiaolan Liu, Lifang Yang, Songling Peng, Zhihui Ding, Tao Feng, Jian Zhou, Jia Fan, Ann M. Bode, Zigang Dong, Jikai Liu, Ya Cao

Published Dec 3, 2014 · Vol. 6, No. 4 · pp. 1995-2008

Altered radiation responses of breast cancer cells resistant to hormonal therapy Research Paper

Lidiya Luzhna, Anne E. Lykkesfeldt, Olga Kovalchuk

Published Dec 2, 2014 · Vol. 6, No. 3 · pp. 1678-1694

Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway Research Paper

Wanxing Duan, Rong Li, Jiguang Ma, Jianjun Lei, Qinhong Xu, Zhengdong Jiang, Ligang Nan, Xuqi Li, Zheng Wang, Xiongwei Huo, Liang Han, Zheng Wu, Erxi Wu, Qingyong Ma

Published Dec 1, 2014 · Vol. 6, No. 3 · pp. 1490-1506

Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity Priority Research Paper

Itsuhiro Takizawa, Mitchell G. Lawrence, Preetika Balanathan, Richard Rebello, Helen B. Pearson, Elika Garg, John Pedersen, Normand Pouliot, Robert Nadon, Matthew J. Watt, Renea A. Taylor, Patrick Humbert, Ivan Topisirovic, Ola Larsson, Gail P. Risbridger, Luc Furic

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 604-616

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper

Schammim Ray Amith, Jodi Marie Wilkinson, Shairaz Baksh, Larry Fliegel

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1262-1275

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells. Research Paper

Itay Pickholtz, Shira Saadyan, Gilmor I. Keshet, Victor S. Wang, Rachel Cohen, Peter Bouwman, Jos Jonkers, Stephen W. Byers, Moshe Z. Papa, Ronit I. Yarden

Published Nov 26, 2014 · Vol. 5, No. 23 · pp. 11827-11846

Short-hairpin RNA library: identification of therapeutic partners for gefitinib-resistant non-small cell lung cancer Research Paper

Makoto Sudo, Seiichi Mori, Vikas Madan, Henry Yang, Geraldine Leong, H. Phillip Koeffler

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 814-824

Intrinsic TGF-Î²2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells Research Paper

Takuya Nakamura, Satoru Shinriki, Hirofumi Jono, Jianying Guo, Mitsuharu Ueda, Mitsuhiro Hayashi, Satoshi Yamashita, Andries Zijlstra, Hideki Nakayama, Akimitsu Hiraki, Masanori Shinohara, Yukio Ando

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 1008-1019

Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype Research Paper

Milone Maria Rita, Pucci Biagio, Bifulco Katia, Iannelli Federica, Lombardi Rita, Chiara Ciardiello, Bruzzese Francesca, Carriero Maria Vincenza, Budillon Alfredo

Published Nov 24, 2014 · Vol. 6, No. 7 · pp. 5324-5341

Keywords: prostate cancer, zoledronic acid, cytoskeleton organization, Î±v integrin, urokinase receptor (uPAR)

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

Nian-Kang Sun, Shang-Lang Huang, Pu-Yuan Chang, Hsing-Pang Lu, Chuck C.-K. Chao

Published Nov 17, 2014 · Vol. 5, No. 23 · pp. 11939-11956

The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma Research Paper

Emmy D.G. Fleuren, Melissa H.S. Hillebrandt-Roeffen, Uta E. Flucke, D. Maroeska W.M. te Loo, Otto C. Boerman, Winette T.A. van der Graaf, Yvonne M.H. Versleijen-Jonkers

Published Nov 15, 2014 · Vol. 5, No. 24 · pp. 12753-12768

Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells Research Paper

Consalvo Petti, Gabriele Picco, Maria Luisa Martelli, Elena Trisolini, Enrico Bucci, Timothy Perera, Claudio Isella, Enzo Medico

Published Nov 15, 2014 · Vol. 6, No. 1 · pp. 221-233

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Novel receptor tyrosine kinase targeted combination therapies for imatinib-resistant gastrointestinal stromal tumors (GIST) Research Paper

Fibroblast growth factor receptor 1 gene amplification is associated with poor survival in patients with resected esophageal squamous cell carcinoma Clinical Research Papers

Targeting of TGF-Î²-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer Research Paper

Î³-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1Î±/VEGF pathways under hypoxic condition Research Paper

RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer Research Paper

New insights into the genetics of glioblastoma multiforme by familial exome sequencing Research Paper

NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma Research Paper

Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe Research Paper

Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFÎ± and ROS production Research Paper

Altered radiation responses of breast cancer cells resistant to hormonal therapy Research Paper

Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway Research Paper

Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity Priority Research Paper

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells. Research Paper

Short-hairpin RNA library: identification of therapeutic partners for gefitinib-resistant non-small cell lung cancer Research Paper

Intrinsic TGF-Î²2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells Research Paper

Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype Research Paper

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma Research Paper

Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Novel receptor tyrosine kinase targeted combination therapies for imatinib-resistant gastrointestinal stromal tumors (GIST) Research Paper

Fibroblast growth factor receptor 1 gene amplification is associated with poor survival in patients with resected esophageal squamous cell carcinoma Clinical Research Papers

Targeting of TGF-Î²-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer Research Paper

Î³-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1Î±/VEGF pathways under hypoxic condition Research Paper

RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer Research Paper

New insights into the genetics of glioblastoma multiforme by familial exome sequencing Research Paper

NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma Research Paper

Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe Research Paper

Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFÎ± and ROS production Research Paper

Altered radiation responses of breast cancer cells resistant to hormonal therapy Research Paper

Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway Research Paper

Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity Priority Research Paper

The Na+/H+ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells. Research Paper

Short-hairpin RNA library: identification of therapeutic partners for gefitinib-resistant non-small cell lung cancer Research Paper

Intrinsic TGF-Î²2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells Research Paper

Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype Research Paper

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma Research Paper

Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells Research Paper

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper