The Oncosearch | Oncotarget

Molecular determinants of drug-specific sensitivity for epidermal growth factor receptor (EGFR) exon 19 and 20 mutants in non-small cell lung cancer Research Paper

Igor F. Tsigelny, Jennifer J. Wheler, Jerry P. Greenberg, Valentina L. Kouznetsova, David J. Stewart, Lyudmila Bazhenova, Razelle Kurzrock

Published Feb 28, 2015 · Vol. 6, No. 8 · pp. 6029-6039

FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells Research Paper

LaTonia Taliaferro-Smith, Elaine Oberlick, Tongrui Liu, Tanisha McGlothen, Tiffanie Alcaide, Rachel Tobin, Siobhan Donnelly, Rachel Commander, Erik Kline, Ganji Purnachandra Nagaraju, Lauren Havel, Adam Marcus, Rita Nahta, Ruth O'Regan

Published Feb 28, 2015 · Vol. 6, No. 7 · pp. 4757-4772

CD133⁺ ovarian cancer stem-like cells promote non-stem cancer cell metastasis via CCL5 induced epithelial-mesenchymal transition Research Paper

Haixia Long, Tong Xiang, Wei Qi, Jiani Huang, Junying Chen, Luhang He, Zhiqing Liang, Bo Guo, Yongsheng Li, Rongkai Xie, Bo Zhu

Published Feb 28, 2015 · Vol. 6, No. 8 · pp. 5846-5859

Simultaneous inhibition of deubiquitinating enzymes (DUBs) and autophagy synergistically kills breast cancer cells Research Paper

Rachel Isaksson Vogel, Kathleen Coughlin, Alessandra Scotti, Yoshie Iizuka, Ravi Anchoori, Richard B.S. Roden, Mauro Marastoni, Martina Bazzaro

Published Feb 27, 2015 · Vol. 6, No. 6 · pp. 4159-4170

In-silico identification and functional validation of allele-dependent AR enhancers Research Paper

Sonia Garritano, Alessandro Romanel, Yari Ciribilli, Alessandra Bisio, Antoneta Gavoci, Alberto Inga, Francesca Demichelis

Published Feb 27, 2015 · Vol. 6, No. 7 · pp. 4816-4828

Targeting the degradation of AXL receptor tyrosine kinase to overcome resistance in gefitinib-resistant non-small cell lung cancer Research Paper

Song Yi Bae, Ji-Young Hong, Hye-Jung Lee, Hyen Joo Park, Sang Kook Lee

Published Feb 26, 2015 · Vol. 6, No. 12 · pp. 10146-10160

A Phase I trial of high dose gefitinib for patients with leptomeningeal metastases from non-small cell lung cancer Clinical Research Papers

David M. Jackman, Leigh Anne Cioffredi, Lorraine Jacobs, Farhana Sharmeen, Linda K. Morse, Joan Lucca, Scott R. Plotkin, Paul J. Marcoux, Michael S. Rabin, Thomas J. Lynch, Bruce E. Johnson, Santosh Kesari

Published Feb 25, 2015 · Vol. 6, No. 6 · pp. 4527-4536

Keywords: â€¢ Carcinoma, non-small-cell lung â€¢ Meningeal carcinomatosis â€¢ Receptor, Epidermal Growth Factor

Radiation-induced PGE₂ sustains human glioma cell growth and survival through EGF signaling Research Paper

Emeline Brocard, Kristell Oizel, Lisenn Lalier, Claire Pecqueur, FranÃ§ois Paris, FranÃ§ois M. Vallette, Lisa Oliver

Published Feb 25, 2015 · Vol. 6, No. 9 · pp. 6840-6849

TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis Research Paper

Jesse Gore, Kelly E. Craven, Julie L. Wilson, Gregory A. Cote, Monica Cheng, Hai V. Nguyen, Harvey M. Cramer, Stuart Sherman, Murray Korc

Published Feb 25, 2015 · Vol. 6, No. 10 · pp. 7504-7521

Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma Research Paper

Tobias Kessler, Felix Sahm, Jonas Blaes, Matthias Osswald, Petra RÃ¼bmann, David Milford, Severino Urban, Leonie Jestaedt, Sabine Heiland, Martin Bendszus, Anne Hertenstein, Philipp-Niclas Pfenning, Carmen Ruiz de AlmodÃ³var, Antje Wick, Frank Winkler, Andreas von Deimling, Michael Platten, Wolfgang Wick, Markus Weiler

Published Feb 19, 2015 · Vol. 6, No. 31 · pp. 31050-31068

miR-145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells Research Paper

Suâ€™e Chang, Ling Gao, Yang Yang, Dongdong Tong, Bo Guo, Liying Liu, Zongfang Li, Tusheng Song, Chen Huang

Published Feb 18, 2015 · Vol. 6, No. 10 · pp. 7675-7685

Adenovirus expressing dual c-Met-specific shRNA exhibits potent antitumor effect through autophagic cell death accompanied by senescence-like phenotypes in glioblastoma cells Research Paper

Jung-Sun Lee, Eonju Oh, Ji Young Yoo, Kyeong Sook Choi, Mi Jin Yoon, Chae-Ok Yun

Published Feb 17, 2015 · Vol. 6, No. 6 · pp. 4051-4065

SKI2162, an inhibitor of the TGF-Î² type I receptor (ALK5), inhibits radiation-induced fibrosis in mice Research Paper

Jin-hong Park, Seung-Hee Ryu, Eun Kyung Choi, Seung Do Anh, Euisun Park, Kyung-Chul Choi, Sang-wook Lee

Published Feb 17, 2015 · Vol. 6, No. 6 · pp. 4171-4179

Keywords: Radiation, Fibrosis, TGF-Î²1, ALK5, SKI2162

Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein Research Paper

Chad M. McKee, Yunchuan Ding, Jianfeng Zhou, Chunrui Li, Liang Huang, Xiangke Xin, Jing He, Joshua E. Allen, Wafik S. El-Deiry, Yunhong Cao, Ruth J. Muschel, Danmei Xu

Published Feb 17, 2015 · Vol. 6, No. 6 · pp. 3784-3796

Upregulated lncRNA-UCA1 contributes to progression of hepatocellular carcinoma through inhibition of miR-216b and activation of FGFR1/ERK signaling pathway Research Paper

Feng Wang, Hou-Qun Ying, Bang-Shun He, Yu-Qin Pan, Qi-Wen Deng, Hui-Ling Sun, Jie Chen, Xian Liu, Shu-Kui Wang

Published Feb 11, 2015 · Vol. 6, No. 10 · pp. 7899-7917

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia Research Paper

Alisa B. Lee-Sherick, Weihe Zhang, Kelly K. Menachof, Amanda A. Hill, Sean Rinella, Gregory Kirkpatrick, Lauren S. Page, Michael A. Stashko, Craig T. Jordan, Qi Wei, Jing Liu, Dehui Zhang, Deborah DeRyckere, Xiaodong Wang, Stephen Frye, H. Shelton Earp, Douglas K. Graham

Published Feb 10, 2015 · Vol. 6, No. 9 · pp. 6722-6736

Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level Research Paper

Jessian L. Munoz, Vivian Rodriguez-Cruz, Shakti H. Ramkissoon, Keith L. Ligon, Steven J. Greco, Pranela Rameshwar

Published Feb 6, 2015 · Vol. 6, No. 2 · pp. 1190-1201

Keywords: glioblastoma, MicroRNA-9, PTCH, Temozolomide, P-gp

Leukemia inhibitory factor receptor is a novel immunomarker in distinction of well-differentiated HCC from dysplastic nodules Research Paper

Qin Luo, Yurong Zhang, Ning Wang, Guangzhi Jin, Haojie Jin, Dishui Gu, Xuemei Tao, Xisong Huo, Tianxiang Ge, Wenming Cong, Cun Wang, Wenxin Qin

Published Feb 5, 2015 · Vol. 6, No. 9 · pp. 6989-6999

Dual targeting of retinoid X receptor and histone deacetylase with DW22 as a novel antitumor approach Research Paper

Lihui Wang, Guoliang Chen, Kang Chen, Yong Ren, Huahuan Li, Xiaorui Jiang, Lina Jia, Shiyuan Fu, Yi Li, Xinwei Liu, Shuang Wang, Jingyu Yang, Chunfu Wu

Published Feb 5, 2015 · Vol. 6, No. 12 · pp. 9740-9755

Inhibition of non-small cell lung cancer (NSCLC) growth by a novel small molecular inhibitor of EGFR Research Paper

Jinsong Li, Huayun Deng, Meichun Hu, Yuanzhang Fang, Amanda Vaughn, Xiaopan Cai, Leqin Xu, Wei Wan, Zhenxi Li, Shijie Chen, Xinghai Yang, Song Wu, Jianru Xiao

Published Feb 5, 2015 · Vol. 6, No. 9 · pp. 6749-6761

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Molecular determinants of drug-specific sensitivity for epidermal growth factor receptor (EGFR) exon 19 and 20 mutants in non-small cell lung cancer Research Paper

FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells Research Paper

CD133⁺ ovarian cancer stem-like cells promote non-stem cancer cell metastasis via CCL5 induced epithelial-mesenchymal transition Research Paper

Simultaneous inhibition of deubiquitinating enzymes (DUBs) and autophagy synergistically kills breast cancer cells Research Paper

In-silico identification and functional validation of allele-dependent AR enhancers Research Paper

Targeting the degradation of AXL receptor tyrosine kinase to overcome resistance in gefitinib-resistant non-small cell lung cancer Research Paper

A Phase I trial of high dose gefitinib for patients with leptomeningeal metastases from non-small cell lung cancer Clinical Research Papers

Radiation-induced PGE₂ sustains human glioma cell growth and survival through EGF signaling Research Paper

TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis Research Paper

Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma Research Paper

miR-145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells Research Paper

Adenovirus expressing dual c-Met-specific shRNA exhibits potent antitumor effect through autophagic cell death accompanied by senescence-like phenotypes in glioblastoma cells Research Paper

SKI2162, an inhibitor of the TGF-Î² type I receptor (ALK5), inhibits radiation-induced fibrosis in mice Research Paper

Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein Research Paper

Upregulated lncRNA-UCA1 contributes to progression of hepatocellular carcinoma through inhibition of miR-216b and activation of FGFR1/ERK signaling pathway Research Paper

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia Research Paper

Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level Research Paper

Leukemia inhibitory factor receptor is a novel immunomarker in distinction of well-differentiated HCC from dysplastic nodules Research Paper

Dual targeting of retinoid X receptor and histone deacetylase with DW22 as a novel antitumor approach Research Paper

Inhibition of non-small cell lung cancer (NSCLC) growth by a novel small molecular inhibitor of EGFR Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Molecular determinants of drug-specific sensitivity for epidermal growth factor receptor (EGFR) exon 19 and 20 mutants in non-small cell lung cancer Research Paper

FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells Research Paper

CD133+ ovarian cancer stem-like cells promote non-stem cancer cell metastasis via CCL5 induced epithelial-mesenchymal transition Research Paper

Simultaneous inhibition of deubiquitinating enzymes (DUBs) and autophagy synergistically kills breast cancer cells Research Paper

In-silico identification and functional validation of allele-dependent AR enhancers Research Paper

Targeting the degradation of AXL receptor tyrosine kinase to overcome resistance in gefitinib-resistant non-small cell lung cancer Research Paper

A Phase I trial of high dose gefitinib for patients with leptomeningeal metastases from non-small cell lung cancer Clinical Research Papers

Radiation-induced PGE2 sustains human glioma cell growth and survival through EGF signaling Research Paper

TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis Research Paper

Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma Research Paper

miR-145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells Research Paper

Adenovirus expressing dual c-Met-specific shRNA exhibits potent antitumor effect through autophagic cell death accompanied by senescence-like phenotypes in glioblastoma cells Research Paper

SKI2162, an inhibitor of the TGF-Î² type I receptor (ALK5), inhibits radiation-induced fibrosis in mice Research Paper

Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein Research Paper

Upregulated lncRNA-UCA1 contributes to progression of hepatocellular carcinoma through inhibition of miR-216b and activation of FGFR1/ERK signaling pathway Research Paper

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia Research Paper

Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level Research Paper

Leukemia inhibitory factor receptor is a novel immunomarker in distinction of well-differentiated HCC from dysplastic nodules Research Paper

Dual targeting of retinoid X receptor and histone deacetylase with DW22 as a novel antitumor approach Research Paper

Inhibition of non-small cell lung cancer (NSCLC) growth by a novel small molecular inhibitor of EGFR Research Paper

CD133⁺ ovarian cancer stem-like cells promote non-stem cancer cell metastasis via CCL5 induced epithelial-mesenchymal transition Research Paper

Radiation-induced PGE₂ sustains human glioma cell growth and survival through EGF signaling Research Paper