The Oncosearch | Oncotarget

Afatinib increases sensitivity to radiation in non-small cell lung cancer cells with acquired EGFR T790M mutation Research Paper

Shirong Zhang, Xiaoliang Zheng, Haixiu Huang, Kan Wu, Bing Wang, Xufeng Chen, Shenglin Ma

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5832-5845

Myeloid differentiation primary response gene 88-leukotriene B4 receptor 2 cascade mediates lipopolysaccharide-potentiated invasiveness of breast cancer cells Research Paper

Geun-Soo Park, Jae-Hong Kim

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5749-5759

Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells Research Paper

Mingyue Zhu, Junli Guo, Wei Li, Yan Lu, Shigan Fu, Xieju Xie, Hua Xia, Xu Dong, Yi Chen, Ming Quan, Shaojiang Zheng, Keping Xie, Mengsen Li

Published Jan 21, 2015 · Vol. 6, No. 14 · pp. 12196-12208

Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma Research Paper

Jiayu Chen, Zijun Y. Xu-Monette, Lijuan Deng, Qi Shen, Ganiraju C. Manyam, Azahara Martinez-Lopez, Li Zhang, Santiago Montes-Moreno, Carlo Visco, Alexandar Tzankov, Lihui Yin, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, AndrÃ©s J.M. Ferreri, Xiaoying Zhao, Michael B. MÃ¸ller, John P. Farnen, Jane N. Winter, Miguel A. Piris, Lan Pham, Ken H. Young

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5597-5614

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

Qiongshu Li, Guomu Liu, Hongyan Yuan, Juan Wang, Yingying Guo, Tanxiu Chen, Ruiping Zhai, Dan Shao, Weihua Ni, Guixiang Tai

Published Jan 20, 2015 · Vol. 6, No. 6 · pp. 4253-4265

Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy Research Paper

FrÃ©dÃ©ric R. Santer, Holger H. H. Erb, Su Jung Oh, Florian Handle, Gertrud E. Feiersinger, Birgit Luef, Huajie Bu, Georg SchÃ¤fer, Christian Ploner, Martina Egger, Jayant K. Rane, Norman J. Maitland, Helmut Klocker, Iris E. Eder, Zoran Culig

Published Jan 14, 2015 · Vol. 6, No. 8 · pp. 6105-6122

EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer Research Paper

Lucas J. Brand, Margaret E. Olson, Preethi Ravindranathan, Hong Guo, Aaron M. Kempema, Timothy E. Andrews, Xiaoli Chen, Ganesh V. Raj, Daniel A. Harki, Scott M. Dehm

Published Jan 12, 2015 · Vol. 6, No. 6 · pp. 3811-3824

Cytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer Research Paper

Hua-Yan Ren, Jian Wang, Fan Yang, Xiao-Li Zhang, Ai-Lian Wang, Li-Li Sun, Ke-Xin Diao, En-Hua Wang, Xiao-Yi Mi

Published Jan 9, 2015 · Vol. 6, No. 6 · pp. 4080-4096

LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients Research Paper

Valeria Cazzaniga, Cristina Bugarin, Michela Bardini, Marco Giordan, Geertruy te Kronnie, Giuseppe Basso, Andrea Biondi, Grazia Fazio, Giovanni Cazzaniga

Published Jan 8, 2015 · Vol. 6, No. 3 · pp. 1569-1581

Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer Research Paper

Parthasarathy Seshacharyulu, Moorthy P. Ponnusamy, Satyanarayana Rachagani, Imayavaramban Lakshmanan, Dhanya Haridas, Ying Yan, Apar K. Ganti, Surinder K. Batra

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5164-5181

Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-Î¸ activation Research Paper

Tetsuyuki Takahashi, Hisanori Uehara, Hirohisa Ogawa, Hitomi Umemoto, Yoshimi Bando, Keisuke Izumi

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4829-4844

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors Research Paper

Sebastian SchÃ¶lch, Conrad Rauber, Alexandra Tietz, Nuh N. Rahbari, Ulrich Bork, Thomas Schmidt, Christoph Kahlert, Uwe Haberkorn, Mark A. Tomai, Kenneth E. Lipson, Rafael Carretero, JÃ¼rgen Weitz, Moritz Koch, Peter E. Huber

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4663-4676

Functional consequence of the MET-T1010I polymorphism in breast cancer Priority Research Paper

Shuying Liu, Funda Meric-Bernstam, Napa Parinyanitikul, Bailiang Wang, Agda K. Eterovic, Xiaofeng Zheng, Mihai Gagea, Mariana Chavez-MacGregor, Naoto T. Ueno, Xiudong Lei, Wanding Zhou, Lakshmy Nair, Debu Tripathy, Powel H. Brown, Gabriel N. Hortobagyi, Ken Chen, John Mendelsohn, Gordon B. Mills, Ana M. Gonzalez-Angulo

Published Dec 31, 2014 · Vol. 6, No. 5 · pp. 2604-2614

Prognostic and predictive value of PDL1 expression in breast cancer Clinical Research Papers

Renaud Sabatier, Pascal Finetti, Emilie Mamessier, JosÃ© Adelaide, Max Chaffanet, Hamid Raza Ali, Patrice Viens, Carlos Caldas, Daniel Birnbaum, FranÃ§ois Bertucci

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5449-5464

CXCR4 over-expression and survival in cancer: A system review and meta-analysis Research Paper

Hongli Zhao, Liyuan Guo, Hong Zhao, Jiaxin Zhao, Hao Weng, Bin Zhao

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5022-5040

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies Research Paper

Lorenzo Tortolina, David J. Duffy, Massimo Maffei, Nicoletta Castagnino, AimÃ©e M. Carmody, Walter Kolch, Boris N. Kholodenko, Cristina De Ambrosi, Annalisa Barla, Elia M. Biganzoli, Alessio Nencioni, Franco Patrone, Alberto Ballestrero, Gabriele Zoppoli, Alessandro Verri, Silvio Parodi

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5041-5058

Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium-dependent apoptosis Research Paper

Kao-Hui Liu, Shun-Tai Yang, Yen-Kuang Lin, Jia-Wei Lin, Yi-Hsuan Lee, Jia-Yi Wang, Chaur-Jong Hu, En-Yuan Lin, Shu-Mei Chen, Chee-Kin Then, Shing-Chuan Shen

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5088-5101

Advances in targeted therapies and new promising targets in esophageal cancer Review

Abbes Belkhiri, Wael El-Rifai

Published Dec 30, 2014 · Vol. 6, No. 3 · pp. 1348-1358

Keywords: adenocarcinoma, esophageal, gastric, cancer, targeted therapy

Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms Research Paper

Daniel Kaemmerer, Christiane Reimann, Elisa Specht, Ralph M. Wirtz, Manal Sayeg, Richard P. Baum, Stefan Schulz, Amelie Lupp

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 3346-3358

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Evgeny A. Moskalev, Pouria Jandaghi, Mahdi Fallah, Mehdi Manoochehri, Sandeep K. Botla, Oleg V. Kolychev, Evgeny A. Nikitin, Vladymyr V. Bubnov, M. von Knebel Doeberitz, Oliver Strobel, Thilo Hackert, Markus W. BÃ¼chler, Nathalia Giese, Andrea Bauer, Thomas Muley, Arne Warth, Peter Schirmacher, Florian Haller, JÃ¶rg D. Hoheisel, Yasser Riazalhosseini

Published Dec 30, 2014 · Vol. 6, No. 6 · pp. 4418-4427

Keywords: DNA methylation, Cancer, Diagnosis, GHSR, Epigenetics

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Afatinib increases sensitivity to radiation in non-small cell lung cancer cells with acquired EGFR T790M mutation Research Paper

Myeloid differentiation primary response gene 88-leukotriene B4 receptor 2 cascade mediates lipopolysaccharide-potentiated invasiveness of breast cancer cells Research Paper

Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells Research Paper

Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma Research Paper

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy Research Paper

EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer Research Paper

Cytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer Research Paper

LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients Research Paper

Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer Research Paper

Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-Î¸ activation Research Paper

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors Research Paper

Functional consequence of the MET-T1010I polymorphism in breast cancer Priority Research Paper

Prognostic and predictive value of PDL1 expression in breast cancer Clinical Research Papers

CXCR4 over-expression and survival in cancer: A system review and meta-analysis Research Paper

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies Research Paper

Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium-dependent apoptosis Research Paper

Advances in targeted therapies and new promising targets in esophageal cancer Review

Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms Research Paper

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Afatinib increases sensitivity to radiation in non-small cell lung cancer cells with acquired EGFR T790M mutation Research Paper

Myeloid differentiation primary response gene 88-leukotriene B4 receptor 2 cascade mediates lipopolysaccharide-potentiated invasiveness of breast cancer cells Research Paper

Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells Research Paper

Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma Research Paper

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy Research Paper

EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer Research Paper

Cytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer Research Paper

LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients Research Paper

Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer Research Paper

Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-Î¸ activation Research Paper

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors Research Paper

Functional consequence of the MET-T1010I polymorphism in breast cancer Priority Research Paper

Prognostic and predictive value of PDL1 expression in breast cancer Clinical Research Papers

CXCR4 over-expression and survival in cancer: A system review and meta-analysis Research Paper

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies Research Paper

Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium-dependent apoptosis Research Paper

Advances in targeted therapies and new promising targets in esophageal cancer Review

Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms Research Paper

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper