The Oncosearch | Oncotarget

Dysregulation of YAP by the Hippo pathway is involved in intervertebral disc degeneration, cell contact inhibition, and cell senescence Research Paper

Cong Zhang, Feng Wang, Zhiyang Xie, Lu Chen, Arjun Sinkemani, Haomin Yu, Kun Wang, Lu Mao, Xiaotao Wu

Published Dec 14, 2017 · Vol. 9, No. 2 · pp. 2175-2192

Jazf1 promotes prostate cancer progression by activating JNK/Slug Research Paper

Yonghun Sung, Song Park, Si Jun Park, Jain Jeong, Minjee Choi, Jinhee Lee, Wookbong Kwon, Soyoung Jang, Mee-Hyun Lee, Dong Joon Kim, Kangdong Liu, Sung-Hyun Kim, Jae-Ho Lee, Yun-Sok Ha, Tae Gyun Kwon, Sanggyu Lee, Zigang Dong, Zae Young Ryoo, Myoung Ok Kim

Published Dec 12, 2017 · Vol. 9, No. 1 · pp. 755-765

Novel proteasome inhibitor delanzomib sensitizes cervical cancer cells to doxorubicin-induced apoptosis via stabilizing tumor suppressor proteins in the p53 pathway Research Paper

Kevin Y. Guo, Lili Han, Xinyu Li, Andrew V. Yang, Jiaxiong Lu, Shan Guan, Hui Li, Yang Yu, Yanling Zhao, Jianhua Yang, Hong Zhang

Published Dec 12, 2017 · Vol. 8, No. 69 · pp. 114123-114135

Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKKβ/NF-κB signaling in mice Research Paper

Jae-Min Cho, Sun-Mi Yun, Young-Ho Choi, Jinyuk Heo, Nam-Jung Kim, Seok-Ho Kim, Eun-Hee Kim

Published Dec 12, 2017 · Vol. 9, No. 1 · pp. 866-880

Mechanism of action and efficacy of LY2109761, a TGF-β receptor inhibitor, targeting tumor microenvironment in liver cancer after TACE Research Paper

Xiaojun He, Xiaopeng Guo, Hongsen Zhang, Xiangchuang Kong, Fan Yang, Chuansheng Zheng

Published Dec 11, 2017 · Vol. 9, No. 1 · pp. 1130-1142

Molecular mechanisms of calcium signaling in the modulation of small intestinal ion transports and bicarbonate secretion Research Paper

Xin Yang, Guorong Wen, Biguang Tuo, Fenglian Zhang, Hanxing Wan, Jialin He, Shiming Yang, Hui Dong

Published Dec 11, 2017 · Vol. 9, No. 3 · pp. 3727-3740

A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy Priority Research Paper

Kelly G. Bryant, Young Chan Chae, Rogelio L. Martinez, John C. Gordon, Khaled M. Elokely, Andrew V. Kossenkov, Steven Grant, Wayne E. Childers, Magid Abou-Gharbia, Dario C. Altieri

Published Dec 11, 2017 · Vol. 8, No. 68 · pp. 112184-112198

Down-regulation of long non-coding RNA ESCCAL_1 inhibits tumor growth of esophageal squamous cell carcinoma in a xenograft mouse model Research Paper

Yuanbo Cui, Wei Wu, Pengju Lv, Jianying Zhang, Bingqing Bai, Wei Cao

Published Dec 11, 2017 · Vol. 9, No. 1 · pp. 783-790

A comparative global phosphoproteomics analysis of obinutuzumab (GA101) versus rituximab (RTX) against RTX sensitive and resistant Burkitt lymphoma (BL) demonstrates differential phosphorylation of signaling pathway proteins after treatment Research Paper

Aradhana Awasthi, Delphine C.M. Rolland, Janet Ayello, Carmella van de Ven, Venkatesha Basrur, Kevin Conlon, Damian Fermin, Matthew J. Barth, Christian Klein, Kojo S.J. Elenitoba-Johnson, Megan S. Lim, Mitchell S. Cairo

Published Dec 9, 2017 · Vol. 8, No. 69 · pp. 113895-113909

CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2Î±-ATF4 pathway Research Paper

Meng-Shian Chen, Sheng-Fan Wang, Chih-Yi Hsu, Pen-Hui Yin, Tien-Shun Yeh, Hsin-Chen Lee, Ling-Ming Tseng

Published Dec 9, 2017 · Vol. 8, No. 70 · pp. 114588-114602

AMRI-59 functions as a radiosensitizer via peroxiredoxin I-targeted ROS accumulation and apoptotic cell death induction Research Paper

Wan Gi Hong, Ju Yeon Kim, Jeong Hyun Cho, Sang-Gu Hwang, Jie-Young Song, EunAh Lee, Tong-Shin Chang, Hong-Duck Um, Jong Kuk Park

Published Dec 9, 2017 · Vol. 8, No. 69 · pp. 114050-114064

Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer Research Paper

Mi Ran Byun, Jin Woo Choi

Published Dec 8, 2017 · Vol. 9, No. 1 · pp. 1041-1047

Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumor-bearing c26 mice Research Paper

Lucia Gatta, Laura Vitiello, Stefania Gorini, Sergio Chiandotto, Paola Costelli, Anna Maria Giammarioli, Walter Malorni, Giuseppe Rosano, Elisabetta Ferraro

Published Dec 8, 2017 · Vol. 8, No. 69 · pp. 113938-113956

Knock-in human GDF5 proregion L373R mutation as a mouse model for proximal symphalangism Research Paper

Xinxin Zhang, Xuesha Xing, Xing Liu, Yu Hu, Shengqiang Qu, Heyi Wang, Yang Luo

Published Dec 8, 2017 · Vol. 8, No. 69 · pp. 113966-113976

Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma Research Paper

Hua Wang, Veerabhadran Baladandayuthapani, Zhiqiang Wang, Heather Lin, Zuzana Berkova, Richard E. Davis, Lin Yang, Robert Z. Orlowski

Published Dec 7, 2017 · Vol. 8, No. 69 · pp. 113858-113873

MicroRNA203a suppresses glioma tumorigenesis through an ATM-dependent interferon response pathway Research Paper

Chuan He Yang, Yinan Wang, Michelle Sims, Chun Cai, Ping He, Hans HÃ¤cker, Junming Yue, Jinjun Cheng, Frederick A. Boop, Lawrence M. Pfeffer

Published Dec 6, 2017 · Vol. 8, No. 68 · pp. 112980-112991

Efficient inhibition of cervical cancer by dual drugs loaded in biodegradable thermosensitive hydrogel composites Research Paper

Shan Xu, XiaoBo Du, Gang Feng, Yu Zhang, Jie Li, Binwei Lin, LingLin Yang, ShaoZhi Fu, JingBo Wu

Published Dec 6, 2017 · Vol. 9, No. 1 · pp. 282-292

Polo-like-kinase 1 (PLK-1) and c-myc inhibition with the dual kinase-bromodomain inhibitor volasertib in aggressive lymphomas Research Paper

Carlos Murga-Zamalloa, Avery Polk, Walter Hanel, Pinki Chowdhury, Noah Brown, Alexandra C. Hristov, Nathanael G. Bailey, Tianjiao Wang, Tycel Phillips, Sumana Devata, Pradeep Poonnen, Juan Gomez-Gelvez, Kedar V. Inamdar, Ryan A. Wilcox

Published Dec 6, 2017 · Vol. 8, No. 70 · pp. 114474-114480

Extracellular signal regulated kinase 5 and inflammasome in progression of mesothelioma Research Paper

Joyce K. Thompson, Anurag Shukla, Alan L. Leggett, Phillip B. Munson, Jill M. Miller, Maximilian B. MacPherson, Stacie L. Beuschel, Harvey I. Pass, Arti Shukla

Published Dec 6, 2017 · Vol. 9, No. 1 · pp. 293-305

MAEL contributes to gastric cancer progression by promoting ILKAP degradation Research Paper

Xing Zhang, Yichong Ning, Yuzhong Xiao, Huaxin Duan, Guifang Qu, Xin Liu, Yan Du, Dejian Jiang, Jianlin Zhou

Published Dec 6, 2017 · Vol. 8, No. 69 · pp. 113331-113344

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Dysregulation of YAP by the Hippo pathway is involved in intervertebral disc degeneration, cell contact inhibition, and cell senescence Research Paper

Jazf1 promotes prostate cancer progression by activating JNK/Slug Research Paper

Novel proteasome inhibitor delanzomib sensitizes cervical cancer cells to doxorubicin-induced apoptosis via stabilizing tumor suppressor proteins in the p53 pathway Research Paper

Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKKβ/NF-κB signaling in mice Research Paper

Mechanism of action and efficacy of LY2109761, a TGF-β receptor inhibitor, targeting tumor microenvironment in liver cancer after TACE Research Paper

Molecular mechanisms of calcium signaling in the modulation of small intestinal ion transports and bicarbonate secretion Research Paper

A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy Priority Research Paper

Down-regulation of long non-coding RNA ESCCAL_1 inhibits tumor growth of esophageal squamous cell carcinoma in a xenograft mouse model Research Paper

A comparative global phosphoproteomics analysis of obinutuzumab (GA101) versus rituximab (RTX) against RTX sensitive and resistant Burkitt lymphoma (BL) demonstrates differential phosphorylation of signaling pathway proteins after treatment Research Paper

CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2Î±-ATF4 pathway Research Paper

AMRI-59 functions as a radiosensitizer via peroxiredoxin I-targeted ROS accumulation and apoptotic cell death induction Research Paper

Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer Research Paper

Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumor-bearing c26 mice Research Paper

Knock-in human GDF5 proregion L373R mutation as a mouse model for proximal symphalangism Research Paper

Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma Research Paper

MicroRNA203a suppresses glioma tumorigenesis through an ATM-dependent interferon response pathway Research Paper

Efficient inhibition of cervical cancer by dual drugs loaded in biodegradable thermosensitive hydrogel composites Research Paper

Polo-like-kinase 1 (PLK-1) and c-myc inhibition with the dual kinase-bromodomain inhibitor volasertib in aggressive lymphomas Research Paper

Extracellular signal regulated kinase 5 and inflammasome in progression of mesothelioma Research Paper

MAEL contributes to gastric cancer progression by promoting ILKAP degradation Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Dysregulation of YAP by the Hippo pathway is involved in intervertebral disc degeneration, cell contact inhibition, and cell senescence Research Paper

Jazf1 promotes prostate cancer progression by activating JNK/Slug Research Paper

Novel proteasome inhibitor delanzomib sensitizes cervical cancer cells to doxorubicin-induced apoptosis via stabilizing tumor suppressor proteins in the p53 pathway Research Paper

Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKKβ/NF-κB signaling in mice Research Paper

Mechanism of action and efficacy of LY2109761, a TGF-β receptor inhibitor, targeting tumor microenvironment in liver cancer after TACE Research Paper

Molecular mechanisms of calcium signaling in the modulation of small intestinal ion transports and bicarbonate secretion Research Paper

A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy Priority Research Paper

Down-regulation of long non-coding RNA ESCCAL_1 inhibits tumor growth of esophageal squamous cell carcinoma in a xenograft mouse model Research Paper

A comparative global phosphoproteomics analysis of obinutuzumab (GA101) versus rituximab (RTX) against RTX sensitive and resistant Burkitt lymphoma (BL) demonstrates differential phosphorylation of signaling pathway proteins after treatment Research Paper

CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2Î±-ATF4 pathway Research Paper

AMRI-59 functions as a radiosensitizer via peroxiredoxin I-targeted ROS accumulation and apoptotic cell death induction Research Paper

Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer Research Paper

Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumor-bearing c26 mice Research Paper

Knock-in human GDF5 proregion L373R mutation as a mouse model for proximal symphalangism Research Paper

Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma Research Paper

MicroRNA203a suppresses glioma tumorigenesis through an ATM-dependent interferon response pathway Research Paper

Efficient inhibition of cervical cancer by dual drugs loaded in biodegradable thermosensitive hydrogel composites Research Paper

Polo-like-kinase 1 (PLK-1) and c-myc inhibition with the dual kinase-bromodomain inhibitor volasertib in aggressive lymphomas Research Paper

Extracellular signal regulated kinase 5 and inflammasome in progression of mesothelioma Research Paper

MAEL contributes to gastric cancer progression by promoting ILKAP degradation Research Paper