The Oncosearch | Oncotarget

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

Osamu Ichiyanagi, Hiromi Ito, Sei Naito, Takanobu Kabasawa, Hidenori Kanno, Takafumi Narisawa, Masaki Ushijima, Yuta Kurota, Michinobu Ozawa, Toshihiko Sakurai, Hayato Nishida, Tomoyuki Kato, Mitsunori Yamakawa, Norihiko Tsuchiya

Published Jun 18, 2019 · Vol. 10, No. 40 · pp. 4053-4068

Keywords: renal cell carcinoma, phospho-eIF4E (p-eIF4E), MNK (MAPK-interacting kinase), recurrence-free, epithelial−mesenchymal transition

ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer Research Paper

Mavee Witherspoon, Davinder Sandu, Changyuan Lu, Kehui Wang, Robert Edwards, Anthony Yeung, Ozkan Gelincik, Giovanni Manfredi, Steven Gross, Levy Kopelovich, Steven Lipkin

Published Jun 18, 2019 · Vol. 10, No. 40 · pp. 4004-4017

Keywords: familial adenomatous polyposis, ethylmalonic encephalopathy 1, mitochondrial bioenergetics, aerobic glycolysis, colorectal cancer

Immunomodulatory and immunotherapeutic implications of tobacco smoking in squamous cell carcinomas and normal airway epithelium Research Perspective

Jingming Wang, Maximilian Linxweiler, Wei Yang, Timothy A. Chan, Luc G.T. Morris

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3835-3839

Keywords: immune, microenvironment

Plasma lncRNA expression profile as a prognostic tool in BRAF-mutant metastatic melanoma patients treated with BRAF inhibitor Research Paper

Tomasz Kolenda, Piotr Rutkowski, Michał Michalak, Katarzyna Kozak, Kacper Guglas, Marcel Ryś, Łukasz Galus, Sebastian Woźniak, Iwona Ługowska, Aleksandra Gos, Anna Teresiak, Andrzej Mackiewicz, Katarzyna Lamperska, Jacek Mackiewicz

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3879-3893

Keywords: melanoma, BRAF mutation, BRAF inhibitor, lncRNA, liquid biopsy

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall Research Paper

Ann M. Moyer, Jia Yu, Jason P. Sinnwell, Travis J. Dockter, Vera J. Suman, Richard M. Weinshilboum, Judy C. Boughey, Matthew P. Goetz, Daniel W. Visscher, Liewei Wang

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3924-3930

Keywords: patient-derived xenografts, breast cancer, Ki67, NOD-SCID mice, NSG mice

Free episomal and integrated HBV DNA in HBsAg-negative patients with intrahepatic cholangiocarcinoma Research Paper

Teresa Pollicino, Cristina Musolino, Carlo Saitta, Gianluca Tripodi, Marika Lanza, Giuseppina Raffa, Francesca Casuscelli di Tocco, Chiara Raggi, Maria Consiglia Bragazzi, Adalberto Barbera, Giuseppe Navarra, Pietro Invernizzi, Domenico Alvaro, Giovanni Raimondo

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3931-3938

Keywords: hepatitis B virus, covalently closed circular HBV DNA, HBV DNA integration, intrahepatic cholangiocarcinoma, occult HBV Infection

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Richard Glenn C. Delacruz, Imelda T. Sandoval, Kyle Chang, Braden N. Miller, Laura Reyes-Uribe, Ester Borras, Patrick M. Lynch, Melissa W. Taggart, Ernest T. Hawk, Eduardo Vilar, David A. Jones

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3939-3951

Keywords: familial adenomatous polyposis, colon cancer, APC, CNOT3, CtBP1

Correction: Infiltrating mast cells increase prostate cancer chemotherapy and radiotherapy resistances via modulation of p38/p53/p21 and ATM signals Correction

Hongjun Xie, Chong Li, Qiang Dang, Luke S. Chang, Lei Li

Published Jun 6, 2019 · Vol. 10, No. 39 · pp. 3978-3978

Development, validation, and comparison of gene analysis methods for detecting EGFR mutation from non-small cell lung cancer patients-derived circulating free DNA Research Paper

Masaki Hanibuchi, Akira Kanoh, Takuya Kuramoto, Tatsuro Saito, Makoto Tobiume, Atsuro Saijo, Hiroyuki Kozai, Mayo Kondo, Shun Morizumi, Hiroto Yoneda, Kozo Kagawa, Hirokazu Ogino, Seidai Sato, Hiroshi Kawano, Kenji Otsuka, Yuko Toyoda, Hiroshi Nokihara, Hisatsugu Goto, Yasuhiko Nishioka

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3654-3666

Keywords: non-small cell lung cancer, circulating free DNA, epidermal growth factor receptor mutation, epidermal growth factor receptor-tyrosine kinase inhibitor

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

Shan-Ju Yeh, Chien-An Chang, Cheng-Wei Li, Lily Hui-Ching Wang, Bor-Sen Chen

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3760-3806

Keywords: lung adenocarcinoma, lung squamous cell carcinoma, NSCLC, genetic and epigenetic network, potential drug target

PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer Research Paper

Sandeep Rajput, Zhanfang Guo, Shunqiang Li, Cynthia X. Ma

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3667-3680

Keywords: PI3K inhibitor, BKM120, eribulin, triple-negative breast cancer, patient-derived xenograft

Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue Research Paper

Moen Sen, Friedrich Hahn, Taylor A. Black, Maureen DeMarshall, Warren Porter, Eileen Snowden, Stephanie S. Yee, Frances Tong, Mitchell Ferguson, Emylee N. Fleshman, Hiroshi Nakagawa, Gary W. Falk, Gregory G. Ginsberg, Michael L. Kochman, Rainer Blaesius, Anil K. Rustgi, Erica L. Carpenter

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3592-3604

Keywords: Barrett’s esophagus, microenvironment, immune cells, single cell, flow cytometry

Dissecting the role of RNA modification regulatory proteins in melanoma Research Paper

Parmanand Malvi, Biao Wang, Shreni Shah, Romi Gupta

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3745-3759

Keywords: RNA modifications, epitranscriptome, melanoma, MAPK, BRAF mutant melanoma

Cancer vaccines: what’s next? Editorial

Stéphane Depil, Paola Bonaventura, Vincent Alcazer

Published May 28, 2019 · Vol. 10, No. 40 · pp. 3985-3987

Keywords: personalised cancer vaccine, neoepitope, immunotherapy

In vitro and in vivo anti-tumor effects of brexpiprazole, a newly-developed serotonin-dopamine activity modulator with an improved safety profile Research Paper

Shuhei Suzuki, Masahiro Yamamoto, Keita Togashi, Tomomi Sanomachi, Asuka Sugai, Shizuka Seino, Takashi Yoshioka, Chifumi Kitanaka, Masashi Okada

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3547-3558

Keywords: brexpiprazole, serotonin-dopamine activity modulator, drug repositioning, drug repurposing, survivin

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamad Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Mohammed S. Al-Baloshi, Sidgi Syed Anwar Abdo Hasson, Ali Al Jabri, Paul A. McCarron, Murtaza M. Tambuwala

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3472-3490

Keywords: melanoma, frankincense, essential oil, apoptosis, tumor remission

Correction: Artocarpin, an isoprenyl flavonoid, induces p53-dependent or independent apoptosis via ROS-mediated MAPKs and Akt activation in non-small cell lung cancer cells Correction

Ming-Horng Tsai, Ju-Fang Liu, Yao-Chang Chiang, Stephen Chu-Sung Hu, Lee-Fen Hsu, Yu-Ching Lin, Zih-Chan Lin, Hui-Chun Lee, Mei-Chuan Chen, Chieh-Liang Huang, Chiang-Wen Lee

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3430-3430

Targeting IL-6 receptor reduces IgM levels and tumor growth in Waldenström macroglobulinemia Research Paper

Weiguo Han, Stephan J. Matissek, David A. Jackson, Brandon Sklavanitis, Sherine F. Elsawa

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3400-3407

Keywords: Waldenström macroglobulinemia, IL-6, Tocilizumab, tumor microenvironment

Molecular biomarkers and precision medicine in colorectal cancer: a systematic review of health economic analyses Review

Raymond Henderson, Declan French, Richard Sullivan, Tim Maughan, Mike Clarke, Mark Lawler

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3408-3423

Keywords: economic analysis, precision medicine, colorectal cancer, biomarker, KRAS

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

Jessie Thalmensi, Elodie Pliquet, Christelle Liard, Gabriel Chamel, Christine Kreuz, Thomas Bestetti, Marie Escande, Anna Kostrzak, Anne-Sophie Pailhes-Jimenez, Emmanuèle Bourges, Marion Julithe, Ludovic Bourre, Olivier Keravel, Pascal Clayette, Thierry Huet, Simon Wain-Hobson, Pierre Langlade-Demoyen

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3361-3372

Keywords: DNA vaccine, canine TERT, cancer, immunotherapy, Electro-Gene-Transfer

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Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer Research Paper

Immunomodulatory and immunotherapeutic implications of tobacco smoking in squamous cell carcinomas and normal airway epithelium Research Perspective

Plasma lncRNA expression profile as a prognostic tool in BRAF-mutant metastatic melanoma patients treated with BRAF inhibitor Research Paper

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall Research Paper

Free episomal and integrated HBV DNA in HBsAg-negative patients with intrahepatic cholangiocarcinoma Research Paper

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Correction: Infiltrating mast cells increase prostate cancer chemotherapy and radiotherapy resistances via modulation of p38/p53/p21 and ATM signals Correction

Development, validation, and comparison of gene analysis methods for detecting EGFR mutation from non-small cell lung cancer patients-derived circulating free DNA Research Paper

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer Research Paper

Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue Research Paper

Dissecting the role of RNA modification regulatory proteins in melanoma Research Paper

Cancer vaccines: what’s next? Editorial

In vitro and in vivo anti-tumor effects of brexpiprazole, a newly-developed serotonin-dopamine activity modulator with an improved safety profile Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Correction: Artocarpin, an isoprenyl flavonoid, induces p53-dependent or independent apoptosis via ROS-mediated MAPKs and Akt activation in non-small cell lung cancer cells Correction

Targeting IL-6 receptor reduces IgM levels and tumor growth in Waldenström macroglobulinemia Research Paper

Molecular biomarkers and precision medicine in colorectal cancer: a systematic review of health economic analyses Review

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer Research Paper

Immunomodulatory and immunotherapeutic implications of tobacco smoking in squamous cell carcinomas and normal airway epithelium Research Perspective

Plasma lncRNA expression profile as a prognostic tool in BRAF-mutant metastatic melanoma patients treated with BRAF inhibitor Research Paper

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall Research Paper

Free episomal and integrated HBV DNA in HBsAg-negative patients with intrahepatic cholangiocarcinoma Research Paper

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Correction: Infiltrating mast cells increase prostate cancer chemotherapy and radiotherapy resistances via modulation of p38/p53/p21 and ATM signals Correction

Development, validation, and comparison of gene analysis methods for detecting EGFR mutation from non-small cell lung cancer patients-derived circulating free DNA Research Paper

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer Research Paper

Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue Research Paper

Dissecting the role of RNA modification regulatory proteins in melanoma Research Paper

Cancer vaccines: what’s next? Editorial

In vitro and in vivo anti-tumor effects of brexpiprazole, a newly-developed serotonin-dopamine activity modulator with an improved safety profile Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Correction: Artocarpin, an isoprenyl flavonoid, induces p53-dependent or independent apoptosis via ROS-mediated MAPKs and Akt activation in non-small cell lung cancer cells Correction

Targeting IL-6 receptor reduces IgM levels and tumor growth in Waldenström macroglobulinemia Research Paper

Molecular biomarkers and precision medicine in colorectal cancer: a systematic review of health economic analyses Review

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper