The Oncosearch | Oncotarget

Neddylation and anti-tumor immunity Research Perspective

Xiaoguang Wang, Scott Best, Alexey V. Danilov

Published Jun 27, 2021 · Vol. 12, No. 21 · pp. 2227-2230

Keywords: neddylation, T cell, pevonedistat

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Rodney J. Scott, Anurag Mehta, Gabriel S. Macedo, Pavel S. Borisov, Ravindran Kanesvaran, Wafaa El Metnawy

Published Jun 22, 2021 · Vol. 12, No. 16 · pp. 1600-1614

Keywords: metastatic castration-resistant prostate cancer, homologous recombination repair, next generation sequencing, genetic testing

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

Tara Williamson, Michelle Carvalho de Abreu, Dimitri G. Trembath, Cory Brayton, Byunghak Kang, Thais Biude Mendes, Paulo Pimentel de Assumpção, Janete M. Cerutti, Gregory J. Riggins

Published Jun 22, 2021 · Vol. 12, No. 14 · pp. 1326-1338

Keywords: mebendazole, pancreatic cancer, cancer prevention, metastasis, mouse models

The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Marina Simón, Jesper Tranekjær Jørgensen, Karina Juhl, Andreas Kjaer

Published Jun 22, 2021 · Vol. 12, No. 14 · pp. 1366-1376

Keywords: photothermal therapy (PTT), indocyanine green (ICG), urokinase plasminogen activator receptor (uPAR), cancer, hyperthermia

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Reza Bayat Mokhtari, Bessi Qorri, Narges Baluch, Angelo Sparaneo, Federico Pio Fabrizio, Lucia Anna Muscarella, Albina Tyker, Sushil Kumar, Hai-Ling Margaret Cheng, Myron R. Szewczuk, Bikul Das, Herman Yeger

Published Jun 22, 2021 · Vol. 12, No. 15 · pp. 1470-1489

Keywords: sulforaphane, acetazolamide, bronchial carcinoid tumors, serotonin, carbonic anhydrase

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Pareesa Kamgar-Dayhoff, Tinatin I. Brelidze

Published Jun 19, 2021 · Vol. 12, No. 14 · pp. 1406-1426

Keywords: chlorpromazine, repurposing

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Kassidy A. Hebert, Sergio Jaramillo, Wangjie Yu, Min Wang, Ratna Veeramachaneni, Vlad C. Sandulache, Andrew G. Sikora, Mark D. Bonnen, Ananth V. Annapragada, David Corry, Farrah Kheradmand, Raj K. Pandita, Michelle S. Ludwig, Tej K. Pandita, Shixia Huang, Cristian Coarfa, Sandra L. Grimm, Dimuthu Perera, George Miles, Yohannes T. Ghebre

Published Jun 19, 2021 · Vol. 12, No. 14 · pp. 1339-1353

Keywords: esomeprazole, proton pump inhibitors, ionizing radiation, radiosensitization, tumor control

Future directions for immunotherapy in meningioma treatment Editorial

John W. Rutland, Jonathan T. Dullea, Raj K. Shrivastava

Published Jun 12, 2021 · Vol. 12, No. 22 · pp. 2300-2301

Keywords: meningioma, immunotherapy, molecular genetics

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study Research Paper

Anjali Gupta, Taofik Oyekunle, Omolola Salako, Adetola Daramola, Olusegun Alatise, Gabriel Ogun, Adewale Adeniyi, April Deveaux, Veeral Saraiya, Allison Hall, Omobolaji Ayandipo, Thomas Olajide, Olalekan Olasehinde, Olukayode Arowolo, Adewale Adisa, Oludolapo Afuwape, Aralola Olusanya, Aderemi Adegoke, Trygve O. Tollefsbol, Donna Arnett, Michael J. Muehlbauer, Christopher B. Newgard, H3 Africa Kidney Research Network, Tomi Akinyemiju

Published Jun 10, 2021 · Vol. 12, No. 13 · pp. 1230-1242

Keywords: C-reactive protein, breast cancer, Nigeria, molecular subtype, menopausal status

Cancer-epigenetic function of the histone methyltransferase KMT2D and therapeutic opportunities for the treatment of KMT2D-deficient tumors Review

Shilpa S. Dhar, Min Gyu Lee

Published Jun 9, 2021 · Vol. 12, No. 13 · pp. 1296-1308

Keywords: cancer, epigenetics, histone methyltransferase, KMT2D, MLL4

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Austin R. Dosch, Walid K. Chatila, Yuguang Ban, Anna Bianchi, Nilesh U. Deshpande, Iago De Castro Silva, Nipun B. Merchant, Jashodeep Datta

Published Jun 1, 2021 · Vol. 12, No. 20 · pp. 2104-2110

Keywords: Ras-p53 cooperativity, Ras, TP53, immune, gastrointestinal cancer

A platform for locoregional T-cell immunotherapy to control HNSCC recurrence following tumor resection Research Paper

Shay Sharon, Jason R. Baird, Shelly Bambina, Gwen Kramer, Tiffany C. Blair, Shawn M. Jensen, Rom S. Leidner, R. Bryan Bell, Nardy Casap, Marka R. Crittenden, Michael J. Gough

Published May 29, 2021 · Vol. 12, No. 13 · pp. 1201-1213

Keywords: head and neck cancer, T-cell, immunotherapy, biomaterial, intratumoral

Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target Research Paper

Natsumi Hayashi, Akitaka Yamasaki, Shiho Ueda, Shogo Okazaki, Yoshiya Ohno, Toshiyuki Tanaka, Yuichi Endo, Yoshihisa Tomioka, Kazue Masuko, Takashi Masuko, Reiko Sugiura

Published May 29, 2021 · Vol. 12, No. 13 · pp. 1256-1270

Keywords: CD98, LAT1, monoclonal antibody, NIH/3T3, oncogenicity

Genomic clustering analysis identifies molecular subtypes of thymic epithelial tumors independent of World Health Organization histologic type Research Paper

Sukhmani K. Padda, Yesim Gökmen-Polar, Jessica A. Hellyer, Sunil S. Badve, Neeraj K. Singh, Sumanth M. Vasista, Kabya Basu, Ansu Kumar, Heather A. Wakelee

Published May 21, 2021 · Vol. 12, No. 12 · pp. 1178-1186

Keywords: thymic epithelial tumor, thymoma, genomics, clustering, computational analysis

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

Lina Alhalhooly, Babak Mamnoon, Jiha Kim, Sanku Mallik, Yongki Choi

Published May 20, 2021 · Vol. 12, No. 12 · pp. 1165-1177

Keywords: cellular stiffness, roughness, adhesion, drug resistance, hypoxia

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma Research Perspective

Anjan Thakurta, William E. Pierceall, Michael D. Amatangelo, Erin Flynt, Amit Agarwal

Published May 19, 2021 · Vol. 12, No. 15 · pp. 1555-1563

Keywords: multiple myeloma, combinations, immunomodulatory agents, apoptosis, protein degradation

Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma Research Paper

Chiara Colarusso, Michela Terlizzi, Anne-Sophie Lamort, Ida Cerqua, Fiorentina Roviezzo, Georgios Stathopoulos, Aldo Pinto, Rosalinda Sorrentino

Published May 7, 2021 · Vol. 12, No. 11 · pp. 1057-1071

Keywords: smoke, COPD, lung cancer, lung inflammation, inflammasome

Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma Research Paper

Rami Mäkelä, Ville Härmä, Nibal Badra Fajardo, Greg Wells, Zoi Lygerou, Olle Sangfelt, Juha Kononen, Juha K. Rantala

Published May 6, 2021 · Vol. 12, No. 11 · pp. 1100-1109

Keywords: cutaneous apocrine sweat gland carcinoma, ex vivo drug screening, DNA repair, PALB2, rare cancer

Activation of plasmacytoid dendritic cells promotes AML-cell fratricide Research Paper

Kavin Fatehchand, Payal Mehta, Christopher B. Colvin, Nathaniel J. Buteyn, Ramasamy Santhanam, Giovanna Merchand-Reyes, Hafza Inshaar, Brenda Shen, Xiaokui Mo, Bethany Mundy-Bosse, Susheela Tridandapani, Jonathan P. Butchar

Published Apr 12, 2021 · Vol. 12, No. 9 · pp. 878-890

Keywords: plasmacytoid dendritic cells, interferon-beta, acute myeloid leukemia, fratricide

Piperlongumine promotes death of retinoblastoma cancer cells Research Paper

Nathalie Allaman-Pillet, Daniel F. Schorderet

Published Apr 8, 2021 · Vol. 12, No. 9 · pp. 907-916

Keywords: cancer, retinoblastoma, piperlongumine, programmed cell death

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Neddylation and anti-tumor immunity Research Perspective

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Future directions for immunotherapy in meningioma treatment Editorial

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study Research Paper

Cancer-epigenetic function of the histone methyltransferase KMT2D and therapeutic opportunities for the treatment of KMT2D-deficient tumors Review

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

A platform for locoregional T-cell immunotherapy to control HNSCC recurrence following tumor resection Research Paper

Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target Research Paper

Genomic clustering analysis identifies molecular subtypes of thymic epithelial tumors independent of World Health Organization histologic type Research Paper

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma Research Perspective

Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma Research Paper

Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma Research Paper

Activation of plasmacytoid dendritic cells promotes AML-cell fratricide Research Paper

Piperlongumine promotes death of retinoblastoma cancer cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Neddylation and anti-tumor immunity Research Perspective

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Future directions for immunotherapy in meningioma treatment Editorial

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study Research Paper

Cancer-epigenetic function of the histone methyltransferase KMT2D and therapeutic opportunities for the treatment of KMT2D-deficient tumors Review

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

A platform for locoregional T-cell immunotherapy to control HNSCC recurrence following tumor resection Research Paper

Oncogenic transformation of NIH/3T3 cells by the overexpression of L-type amino acid transporter 1, a promising anti-cancer target Research Paper

Genomic clustering analysis identifies molecular subtypes of thymic epithelial tumors independent of World Health Organization histologic type Research Paper

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma Research Perspective

Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma Research Paper

Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma Research Paper

Activation of plasmacytoid dendritic cells promotes AML-cell fratricide Research Paper

Piperlongumine promotes death of retinoblastoma cancer cells Research Paper