The Oncosearch | Oncotarget

The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey Research Paper

Subotheni Thavaneswaran, Mandy Ballinger, Phyllis Butow, Bettina Meiser, David Goldstein, Frank Lin, Christine Napier, David Thomas, Megan Best

Published Sep 9, 2021 · Vol. 12, No. 21 · pp. 2169-2176

Keywords: comprehensive genomic profiling, precision medicine, targeted treatment selection using genomics, communication, clinicians' experiences with utilising genomic findings in a pan-cancer setting to inform treatment selection

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Lindsey Carlsen, Christoph Schorl, Kelsey Huntington, Liz Hernandez-Borrero, Aakash Jhaveri, Shengliang Zhang, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 8, 2021 · Vol. 12, No. 20 · pp. 2006-2021

Keywords: chemotherapy mechanism, colon cancer, 5-fluorouracil, irinotecan, oxaliplatin

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Erling Håland, Ingrid Nyhus Moen, Elias Veidal, Hanne Hella, Kristine Misund, Tobias S. Slørdahl, Kristian K. Starheim

Published Sep 4, 2021 · Vol. 12, No. 21 · pp. 2158-2168

Keywords: multiple myeloma, TAK1, apoptosis, NF-κB, cancer treatment

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Jan A. Kaczmarczyk, Rhonda R. Roberts, Brian T. Luke, King C. Chan, Carly M. Van Wagoner, Robin A. Felder, Richard G. Saul, Colantonio Simona, Josip Blonder

Published Sep 3, 2021 · Vol. 12, No. 20 · pp. 2022-2038

Keywords: lung cancer, proteomics, 2D vs. 3D cultured cells, preclinical testing model, drug target discovery

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Trupti Vardam-Kaur, Latha B. Pathangey, Daniel J. McCormick, P. Leif Bergsagel, Peter A. Cohen, Sandra J. Gendler

Published Aug 27, 2021 · Vol. 12, No. 20 · pp. 2051-2067

Keywords: multiple myeloma, cellular therapy, CD4/CD8 T cells, peptides, immunotherapy

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

Sayantani Chatterjee, Julian Ugonotti, Ling Y. Lee, Arun Everest-Dass, Rebeca Kawahara, Morten Thaysen-Andersen

Published Aug 24, 2021 · Vol. 12, No. 21 · pp. 2188-2205

Keywords: oligomannose, α1,2-mannosidase, cancer, glycomics, mass spectrometry

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Marcel Kemper, Georg Evers, Arik Bernard Schulze, Jan Sperveslage, Christoph Schülke, Georg Lenz, Thomas Herold, Wolfgang Hartmann, Hans-Ulrich Schildhaus, Annalen Bleckmann

Published Aug 23, 2021 · Vol. 12, No. 19 · pp. 1946-1952

Keywords: NSCLC, resistance mutations, ALK, KRAS, ALK inhibitors

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Brenna M. Zimmer, Michelle E. Howell, Linlin Ma, Jeffrey R. Enders, Danielle Lehman, Eva Corey, Joseph J. Barycki, Melanie A. Simpson

Published Aug 19, 2021 · Vol. 12, No. 19 · pp. 1886-1902

Keywords: prostate cancer, castration resistance, detoxification, UDP-glucose dehydrogenase, patient-derived xenografts

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Matthew Devall, Christopher H. Dampier, Stephen Eaton, Mourad W. Ali, Virginia Díez-Obrero, Ferran Moratalla-Navarro, Jennifer Bryant, Lucas T. Jennelle, Victor Moreno, Steven M. Powell, Ulrike Peters, Graham Casey

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1863-1877

Keywords: colon organoids, microsatellite instability, smoking, single-cell deconvolution, weighted gene co-expression network analysis

High expression of Myosin 1g in pediatric acute lymphoblastic leukemia Research Paper

Laura A. Estrada-Abreo, Leonor Rodríguez-Cruz, Yanelly Garfias-Gómez, Janeth E. Araujo-Cardenas, Gabriela Antonio-Andrés, Alfonso R. Salgado-Aguayo, Darío Orozco-Ruiz, José Refugio Torres-Nava, Juan D. Díaz-Valencia, Sara Huerta-Yépez, Genaro Patiño-López

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1937-1945

Keywords: Myosin 1g, acute lymphoblastic leukemia, high risk, biomarker, pediatric

Anti-aging: senolytics or gerostatics (unconventional view) Review

Mikhail V. Blagosklonny

Published Aug 12, 2021 · Vol. 12, No. 18 · pp. 1821-1835

Keywords: geroscience, senolytics, hyperfunction theory, aging, sirolimus

Abstract_headers_test_v1_The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Marina Simón, Jesper Tranekjær Jørgensen, Karina Juhl, Andreas Kjaer

Published Aug 3, 2021

Keywords: photothermal therapy (PTT), indocyanine green (ICG), urokinase plasminogen activator receptor (uPAR), cancer, hyperthermia

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

Miguel Vizoso, Jacco van Rheenen

Published Jul 29, 2021 · Vol. 12, No. 17 · pp. 1651-1662

Keywords: targeted DNA methylation, CRISPR/Cas9-based system, IGFBP2, epithelial-to-mesenchymal transition

UBE2T: A new molecular regulator of cancer stemness in hepatocellular carcinoma Editorial

Rainbow Wing Hei Leung, Nicole Pui Yu Ho, Carmen Oi Ning Leung, Terence Kin Wah Lee

Published Jul 24, 2021 · Vol. 12, No. 17 · pp. 1727-1728

Keywords: beta-catenin, cancer stem cells, UBE2T, hepatocellular carcinoma

Epigenetic signatures differentiate uterine and soft tissue leiomyosarcoma Research Paper

Nesrin M. Hasan, Anup Sharma, Nensi M. Ruzgar, Hari Deshpande, Kelly Olino, Sajid Khan, Nita Ahuja

Published Jul 21, 2021 · Vol. 12, No. 16 · pp. 1566-1579

Keywords: leiomyosarcoma, epigenetics, DNA methylation, gene expression, uterine leiomyosarcoma

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Correction

Maria Grazia Vizioli, Joana Santos, Silvana Pilotti, Mara Mazzoni, Maria Chiara Anania, Claudia Miranda, Sonia Pagliardini, Marco A. Pierotti, Jesus Gil, Angela Greco

Published Jul 2, 2021 · Vol. 13, No. 1 · pp. 1120-1121

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Subarna Ghosh, Priyanka Dey Talukdar, Abhinandan Bhattacharjee, Sarbani Giri, Nitai Pada Bhattacharyya, Urmi Chatterji

Published Jul 2, 2021 · Vol. 12, No. 15 · pp. 1520-1539

Keywords: arecoline, tight junction, head and neck cancer, lncRNA-NEAT1, JunD

RNA expression differences in prostate tumors and tumor-adjacent stroma between Black and White Americans Research Paper

Farah Rahmatpanah, Gabriela De Robles, Michael Lilly, Thomas Keane, Vinay Kumar, Dan Mercola, Pavneet Randhawa, Michael McClelland

Published Jun 29, 2021 · Vol. 12, No. 15 · pp. 1457-1469

Keywords: prostate cancer, tumor-adjacent stroma, African ancestry, European ancestry, RNA-seq analysis

Identification of miR-203a, mir-10a, and miR-194 as predictors for risk of lymphovascular invasion in head and neck cancers Research Paper

Moumita Karmakar, Pei-Chun Lai, Samiran Sinha, Shannon Glaser, Sanjukta Chakraborty

Published Jun 28, 2021 · Vol. 12, No. 15 · pp. 1499-1519

Keywords: miRNA, supervised clustering, random forest, TCGA, head neck cancer

Actionability evaluation of biliary tract cancer by genome transcriptome analysis and Asian cancer knowledgebase Research Paper

Yuki Okawa, Nobutaka Ebata, Nayoung K.D. Kim, Masashi Fujita, Kazuhiro Maejima, Shota Sasagawa, Toru Nakamura, Woong-Yang Park, Satoshi Hirano, Hidewaki Nakagawa

Published Jun 28, 2021 · Vol. 12, No. 15 · pp. 1540-1552

Keywords: biliary tract cancer, mutation, immunotherapic biomarker, knowledgebase, molecular targeted therapy

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The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey Research Paper

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

High expression of Myosin 1g in pediatric acute lymphoblastic leukemia Research Paper

Anti-aging: senolytics or gerostatics (unconventional view) Review

Abstract_headers_test_v1_The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

UBE2T: A new molecular regulator of cancer stemness in hepatocellular carcinoma Editorial

Epigenetic signatures differentiate uterine and soft tissue leiomyosarcoma Research Paper

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Correction

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

RNA expression differences in prostate tumors and tumor-adjacent stroma between Black and White Americans Research Paper

Identification of miR-203a, mir-10a, and miR-194 as predictors for risk of lymphovascular invasion in head and neck cancers Research Paper

Actionability evaluation of biliary tract cancer by genome transcriptome analysis and Asian cancer knowledgebase Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey Research Paper

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma Research Paper

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

High expression of Myosin 1g in pediatric acute lymphoblastic leukemia Research Paper

Anti-aging: senolytics or gerostatics (unconventional view) Review

Abstract_headers_test_v1_The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

UBE2T: A new molecular regulator of cancer stemness in hepatocellular carcinoma Editorial

Epigenetic signatures differentiate uterine and soft tissue leiomyosarcoma Research Paper

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Correction

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

RNA expression differences in prostate tumors and tumor-adjacent stroma between Black and White Americans Research Paper

Identification of miR-203a, mir-10a, and miR-194 as predictors for risk of lymphovascular invasion in head and neck cancers Research Paper

Actionability evaluation of biliary tract cancer by genome transcriptome analysis and Asian cancer knowledgebase Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper