The Oncosearch | Oncotarget

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Nathalie Sphyris, Cody King, Jonathan Hoar, Steven J. Werden, Geraldine V. Vijay, Naoyuki Miura, Akhilesh Gaharwar, Tapasree Roy Sarkar

Published Mar 30, 2021 · Vol. 12, No. 8 · pp. 823-844

Keywords: angiogenesis, endothelial transdifferentiation, epithelial-mesenchymal transition, vasculogenic mimicry, FOXC2

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Nathalie Sphyris, Cody King, Jonathan Hoar, Steven J. Werden, Geraldine V. Vijay, Naoyuki Miura, Akhilesh Gaharwar, Tapasree Roy Sarkar

Published Mar 30, 2021

Keywords: angiogenesis, endothelial transdifferentiation, epithelial-mesenchymal transition, vasculogenic mimicry, FOXC2

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Sateja Paradkar, James Herrington, Adam Hendricson, Piyasena Hewawasam, Mark Plummer, Denton Hoyer, Ranjini K. Sundaram, Yulia V. Surovtseva, Ranjit S. Bindra

Published Mar 27, 2021 · Vol. 12, No. 9 · pp. 891-906

Keywords: glioblastoma, radiosensitizers, mibefradil, DNA repair, alternative non-homologous end joining

Evaluation of liver kinase B1 downstream signaling expression in various breast cancers and relapse free survival after systemic chemotherapy treatment Review

Khoa Nguyen, Andrew Rivera, Madlin Alzoubi, Henri Wathieu, Shengli Dong, Hassan Yousefi, Margarite Matossian, Suresh Alahari, David Drewry, Matthew Burow, Bridgette Collins-Burow

Published Mar 23, 2021 · Vol. 12, No. 11 · pp. 1110-1115

Keywords: LKB1, STK11, breast cancer, triple negative breast cancer, patient prognosis

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Chandni Desai, Jon Thomason, Jordan L. Kohlmeyer, Anna C. Reisetter, Parmanand Ahirwar, Khadijeh Jahanseir, Mariah Leidinger, Georgina Ofori-Amanfo, Karen Fritchie, Sadanandan E. Velu, Patrick Breheny, Dawn E. Quelle, Munir R. Tanas

Published Mar 21, 2021 · Vol. 12, No. 8 · pp. 740-755

Keywords: sarcoma, YAP, TAZ, p53-MDM2, RABL6A

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Brittany Mull, Ryan Davis, Iqbal Munir, Mia C. Perez, Alfred A. Simental, Salma Khan

Published Mar 12, 2021 · Vol. 12, No. 7 · pp. 596-607

Keywords: DBP, thyroid cancer, health disparities

Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma Research Paper

Julien Schaller, Hélène Maby-El Hajjami, Sylvie Rusakiewicz, Kalliopi Ioannidou, Nathalie Piazzon, Alexandra Miles, Déla Golshayan, Olivier Gaide, Daniel Hohl, Daniel E. Speiser, Karin Schaeuble

Published Mar 5, 2021 · Vol. 12, No. 7 · pp. 638-648

Keywords: lymphatic vessel, CD8+ T cell, perineural infiltration, skin squamous-cell carcinoma, tumor immunology

Prognostic significance of isochromosome 17q in hematologic malignancies Case Report

Dorota Koczkodaj, Justyna Muzyka-Kasietczuk, Sylwia Chocholska, Monika Podhorecka

Published Mar 5, 2021 · Vol. 12, No. 7 · pp. 708-718

Keywords: isochromosome 17q, karyotype, FISH, hematologic malignancies, prognosis

Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells Research Paper

Bhaskar Bhattacharya, Daniel Q. Huang, Sarah Hong Hui Low, Gim Hwa Tan, Min Ji Han, Sanamerjit Singh, Benny Tang, Sheng Chun Chang, Joey Sze Yun Lim, Mohd Feroz Mohd Omar, Yock Young Dan, Richie Soong

Published Mar 3, 2021 · Vol. 12, No. 7 · pp. 674-685

Keywords: drug development, microenvironment, glycolysis

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Duna H. Barakeh, Rasha Aljelaify, Yara Bashawri, Amal Almutairi, Fatimah Alqubaishi, Mohammed Alnamnakani, Latifa Almubarak, Abdulrahman Al Naeem, Fatema Almushawah, May Alrashed, Malak Abedalthagafi

Published Feb 27, 2021 · Vol. 12, No. 7 · pp. 686-697

Keywords: breast cancer, PIK3CA, BCa, Saudi Arabia, BRCA

Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations Research Paper

Asim Joshi, Rohit Mishra, Sanket Desai, Pratik Chandrani, Hitesh Kore, Roma Sunder, Supriya Hait, Prajish Iyer, Vaishakhi Trivedi, Anuradha Choughule, Vanita Noronha, Amit Joshi, Vijay Patil, Nandini Menon, Rajiv Kumar, Kumar Prabhash, Amit Dutt

Published Feb 19, 2021 · Vol. 12, No. 6 · pp. 578-588

Keywords: lung squamous carcinoma, genetic alterations, druggable mutations, whole exome sequencing, mass spectrometry

Pancreatic cancer driver mutations are targetable through distant alternative RNA splicing dependencies Research Perspective

Ryan R. Kawalerski, Steven D. Leach, Luisa F. Escobar-Hoyos

Published Feb 12, 2021 · Vol. 12, No. 6 · pp. 525-533

Keywords: pancreatic cancer, RNA splicing, targeted therapy, KRAS, TP53

The role of immune surveillance in malignant transformation of benign salivary gland tumors Research Perspective

Maximilian Linxweiler, Jingming Wang, Luc G.T. Morris

Published Feb 10, 2021 · Vol. 12, No. 7 · pp. 592-595

Keywords: salivary tumor, salivary cancer, pleomorphic adenoma, immune surveillance

Mutational profile of skin lesions in hepatocellular carcinoma patients under tyrosine kinase inhibition: a repercussion of a wide-spectrum activity Research Paper

Leonardo G. da Fonseca, Carla Fuster-Anglada, Cristina Carrera, Cristina Millán, Esther Samper, Victor Sapena, Álvaro Díaz-González, Marco Sanduzzi-Zamparelli, Cassia Leal, Alejandro Forner, Jordi Bruix, Maria Reig, Loreto Boix, Alba Díaz

Published Feb 5, 2021 · Vol. 12, No. 5 · pp. 440-449

Keywords: hepatocellular carcinoma, tyrosine kinase inhibitors, treatment adverse events, skin lesions, molecular profiling

Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry Research Paper

Juan Pablo Cerapio, Agnès Marchio, Luis Cano, Ignacio López, Jean-Jacques Fournié, Béatrice Régnault, Sandro Casavilca-Zambrano, Eloy Ruiz, Anne Dejean, Stéphane Bertani, Pascal Pineau

Published Feb 3, 2021 · Vol. 12, No. 5 · pp. 475-492

Keywords: hepatitis B virus, indigenous people, integrative genomics, liver cancer

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast Research Paper

Aviral Kumar, David S. Nayakanti, Kiran K. Mangalaparthi, Veena Gopinath, Nandyala Venkat Narsimha Reddy, Krishna Govindan, Geeta Voolapalli, Prashant Kumar, Lekha Dinesh Kumar

Published Feb 3, 2021 · Vol. 12, No. 5 · pp. 507-518

Keywords: breast tumors, fibroepithelial lesions, phyllodes, iTRAQ, quantitative proteomics

Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors Research Paper

Naoko Takebe, Geraldine O'Sullivan Coyne, Shivaani Kummar, Jerry Collins, Joel M. Reid, Richard Piekarz, Nancy Moore, Lamin Juwara, Barry C. Johnson, Rachel Bishop, Frank I. Lin, Esther Mena, Peter L. Choyke, M. Liza Lindenberg, Larry V. Rubinstein, Cecilia Monge Bonilla, Matthew P. Goetz, Matthew M. Ames, Renee M. McGovern, Howard Streicher, Joseph M. Covey, James H. Doroshow, Alice P. Chen

Published Feb 1, 2021 · Vol. 12, No. 4 · pp. 268-277

Keywords: Z-endoxifen, phase 1, tamoxifen, pharmacokinetics

Intratumoral immunotherapy with STING agonist, ADU-S100, induces CD8+ T-cell mediated anti-tumor immunity in an esophageal adenocarcinoma model Research Paper

Ali H. Zaidi, Ronan J. Kelly, Anastasia Gorbunova, Ashten N. Omstead, Madison S. Salvitti, Ping Zheng, Juliann E. Kosovec, Soyoung Lee, Shahin Ayazi, Laila Babar, Gene G. Finley, Ajay Goel, Blair A. Jobe

Published Feb 1, 2021 · Vol. 12, No. 4 · pp. 292-303

Keywords: esophageal adenocarcinoma, STING, PD-L1, CD8+ T-cells, IFNβ

Cancer stem cells and macrophages: molecular connections and future perspectives against cancer Review

Beatrice Aramini, Valentina Masciale, Giulia Grisendi, Federico Banchelli, Roberto D’Amico, Antonino Maiorana, Uliano Morandi, Massimo Dominici, Khawaja Husnain Haider

Published Jan 27, 2021 · Vol. 12, No. 3 · pp. 230-250

Keywords: cancer stem cells, macrophages, future perspectives, cancer, target treatments

Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach Research Paper

Enric Carcereny, Alonso Fernández-Nistal, Araceli López, Carmen Montoto, Andrea Naves, Cristina Segú-Vergés, Mireia Coma, Guillem Jorba, Baldomero Oliva, Jose Manuel Mas

Published Jan 22, 2021 · Vol. 12, No. 4 · pp. 316-332

Keywords: ALK inhibitor, brigatinib, alectinib, mathematical model, systems biology

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Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Evaluation of liver kinase B1 downstream signaling expression in various breast cancers and relapse free survival after systemic chemotherapy treatment Review

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma Research Paper

Prognostic significance of isochromosome 17q in hematologic malignancies Case Report

Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells Research Paper

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations Research Paper

Pancreatic cancer driver mutations are targetable through distant alternative RNA splicing dependencies Research Perspective

The role of immune surveillance in malignant transformation of benign salivary gland tumors Research Perspective

Mutational profile of skin lesions in hepatocellular carcinoma patients under tyrosine kinase inhibition: a repercussion of a wide-spectrum activity Research Paper

Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry Research Paper

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast Research Paper

Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors Research Paper

Intratumoral immunotherapy with STING agonist, ADU-S100, induces CD8+ T-cell mediated anti-tumor immunity in an esophageal adenocarcinoma model Research Paper

Cancer stem cells and macrophages: molecular connections and future perspectives against cancer Review

Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Evaluation of liver kinase B1 downstream signaling expression in various breast cancers and relapse free survival after systemic chemotherapy treatment Review

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma Research Paper

Prognostic significance of isochromosome 17q in hematologic malignancies Case Report

Effect of cell microenvironment on the drug sensitivity of hepatocellular cancer cells Research Paper

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations Research Paper

Pancreatic cancer driver mutations are targetable through distant alternative RNA splicing dependencies Research Perspective

The role of immune surveillance in malignant transformation of benign salivary gland tumors Research Perspective

Mutational profile of skin lesions in hepatocellular carcinoma patients under tyrosine kinase inhibition: a repercussion of a wide-spectrum activity Research Paper

Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry Research Paper

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast Research Paper

Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors Research Paper

Intratumoral immunotherapy with STING agonist, ADU-S100, induces CD8+ T-cell mediated anti-tumor immunity in an esophageal adenocarcinoma model Research Paper

Cancer stem cells and macrophages: molecular connections and future perspectives against cancer Review

Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach Research Paper