The Oncosearch | Oncotarget

Pathways and therapeutic targets in melanoma Review

Emma Shtivelman, Michael A. Davies, Patrick Hwu, James Yang, Michal Lotem, Moshe Oren, Keith T. Flaherty, David E. Fisher

Published Apr 8, 2014 · Vol. 5, No. 7 · pp. 1701-1752

Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells. Research Paper

Claire B. Pollock, Sara McDonough, Victor S. Wang, Hyojung Lee, Lymor Ringer, Xin Li, Cristina Prandi, Richard J. Lee, Adam S. Feldman, Hinanit Koltai, Yoram Kapulnik, Olga C. Rodriguez, Richard Schlegel, Christopher Albanese, Ronit I. Yarden

Published Apr 2, 2014 · Vol. 5, No. 6 · pp. 1683-1698

PDGFRÎ± up-regulation mediated by Sonic Hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation Research Paper

Francesco Sabbatino, Yangyang Wang, Xinhui Wang, Keith T. Flaherty, Ling Yu, David Pepin, Giosueâ€™ Scognamiglio, Stefano Pepe, John M. Kirkwood, Zachary A. Cooper, Dennie T. Frederick, Jennifer A. Wargo, Soldano Ferrone, Cristina R. Ferrone

Published Mar 31, 2014 · Vol. 5, No. 7 · pp. 1926-1941

The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells Research Paper

Joseph Mazar, Wei Zhao, Ahmad M. Khalil, Bongyong Lee, John Shelley, Subramaniam S. Govindarajan, Fumiko Yamamoto, Maya Ratnam, Muhammad Nauman Aftab, Sheila Collins, Brian N. Finck, Xianlin Han, John S. Mattick, Marcel E. Dinger, Ranjan J. Perera

Published Mar 26, 2014 · Vol. 5, No. 19 · pp. 8959-8969

Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation Research Paper

Tom Groot Kormelink, Desmond G. Powe, Sylvia A. Kuijpers, Abulikemu Abudukelimu, Marcel H.A.M. Fens, Ebel H.E. Pieters, Willemiek W. Kassing-van der Ven, Hany O. Habashy, Ian O. Ellis, Bart R. Blokhuis, Marco Thio, Wim E. Hennink, Gert Storm, Frank A. Redegeld, Raymond M. Schiffelers

Published Mar 26, 2014 · Vol. 5, No. 10 · pp. 3159-3167

Eradication of metastatic melanoma through cooperative expression of RNA-based HDAC1 inhibitor and p73 by oncolytic adenovirus Research Paper

Holger Schipper, Vijay Alla, Claudia Meier, Dirk M. Nettelbeck, Ottmar HerchenrÃ¶der, Brigitte M. PÃ¼tzer

Published Mar 21, 2014 · Vol. 5, No. 15 · pp. 5893-5907

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style Research Paper

Francesca Margheri, Cristina Luciani, Maria Letizia Taddei, Elisa Giannoni, Anna Laurenzana, Alessio Biagioni, Anastasia ChillÃ, Paola Chiarugi, Gabriella Fibbi, Mario Del Rosso

Published Mar 10, 2014 · Vol. 5, No. 6 · pp. 1538-1553

Keywords: uPAR, mesenchymal movement, amoeboid movement, prostate carcinoma, melanoma

SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells Research Paper

MickaÃ«l Ohanna, Caroline Bonet, Karine Bille, Maryline Allegra, Irwin Davidson, Philippe Bahadoran, Jean-Philippe Lacour, Robert Ballotti, Corine Bertolotto

Published Feb 19, 2014 · Vol. 5, No. 8 · pp. 2085-2095

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Powrnima Joshi, Barbara Jacobs, Adeeb Derakhshan, Lee R. Moore, Paul Elson, Pierre L. Triozzi, Ernest Borden, Maciej Zborowski

Published Feb 3, 2014 · Vol. 5, No. 9 · pp. 2450-2461

Keywords: circulating melanoma cells, CTC, Melan-A, S100B, magnetic separation, negative selection

FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Research Paper

Bee Shin Tan, Matthew R Anaka, Siddhartha Deb, Claudia Freyer, Lisa M Ebert, Anderly C Chueh, Sheren Al-Obaidi, Andreas Behren, Aparna Jayachandran, Jonathan Cebon, Weisan Chen, John M Mariadason

Published Dec 20, 2013 · Vol. 5, No. 1 · pp. 264-276

Keywords: FOXP3, melanoma, proliferation, apoptosis

Plasticity of melanoma and EMT-TF reprogramming Editorial Materials

Eugene Tulchinsky, J. Howard Pringle, Julie Caramel, StÃ©phane Ansieau

Published Dec 19, 2013 · Vol. 5, No. 1 · pp. 1-2

Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer. Research Paper

MarÃa JosÃ© Escamez, Francisco Garcia-Garcia, Gemma Tell-Marti, Angels Fabra, LucÃa MartÃnez-SantamarÃa, Celia Badenas, Paula Aguilera, Marta Pevida, JoaquÃn Dopazo, Marcela del RÃo, Susana Puig

Published Dec 16, 2013 · Vol. 5, No. 6 · pp. 1439-1451

Keywords: Familial Melanoma, CDKN2A, MC1R, gene expression, p16, mutations

The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model Brief Reports

Sebastian Kobold, Melanie Merk, Luisa Hofer, Philip Peters, Richard Bucala, Stefan Endres

Published Dec 12, 2013 · Vol. 5, No. 1 · pp. 103-107

Keywords: Cytokine, MIF, cancer, apoptosis

Chemokines in tumor progression and metastasis Review

Purvaba J. Sarvaiya, Donna Guo, Ilya V. Ulasov, Patrik Gabikian, Maciej S. Lesniak

Published Nov 9, 2013 · Vol. 4, No. 12 · pp. 2171-2185

Keywords: Chemokines, chemokine receptors, cancer, metastasis

Mitochondrial oxidative stress is the achilleâ€™s heel of melanoma cells resistant to Braf-mutant inhibitor Research Paper

Paola Corazao-Rozas, Pierre Guerreschi, Manel Jendoubi, Fanny AndrÃ©, AurÃ©lie Jonneaux, Camille Scalbert, Guillaume GarÃ§on, Myriam Mallet-Martino, StÃ©phane Balayssac, Stephane Rocchi, Ariel Savina, Pierre Formstecher, Laurent Mortier, Jerome Kluza, Philippe Marchetti

Published Oct 6, 2013 · Vol. 4, No. 11 · pp. 1986-1998

Keywords: metabolism, oxidative phosphorylation, elesclomol, ROS

Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector Research Paper

Franco Venanzi, Victor Shifrin, Michael Y. Sherman, Vladimir Gabai, Oleg Kisilev, Andrey Komissarov, Mikhail Grudinin, Maria Shartakova, Ekaterina Romanovskaya-Romanko, Yuri Kudryavets, Natalya Bezdenezhnykh, Oleksandra Lykhova, Nadiia Semesyuk, Antonio Concetti, Anatoly Tsyb, Marina Filimonova, Victoria Makarchuk, Raisa Yakubovsky, Andrey Chursov, Vita Shcherbinina, Alexander Shneider

Published Oct 2, 2013 · Vol. 4, No. 10 · pp. 1829-1835

Keywords: cancer immunotherapy, DNA vaccine, autophagy, metastases

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

Xiaoping Wu, Huixian Huang, Cong Wang, Shaoqiang Lin, Yadong Huang, Yi Wang, Guang Liang, Qiuxia Yan, Jian Xiao, Jianzhang Wu, Yongguang Yang, Xiaokun Li

Published Oct 1, 2013 · Vol. 4, No. 10 · pp. 1819-1828

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

Andrea Treszl, Zita Steiber, Andrew V Schally, Norman L Block, Balazs Dezso, Gabor Olah, Bernadett Rozsa, Klara Fodor, Armin Buglyo, Janos Gardi, Andras Berta, Gabor Halmos

Published Sep 10, 2013 · Vol. 4, No. 10 · pp. 1721-1728

Keywords: uveal melanoma, luteinizing hormone-releasing hormone (LHRH) receptor

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

Sandra Cascio, Adam M Farkas, Rebecca P Hughey, Olivera J Finn

Published Sep 7, 2013 · Vol. 4, No. 10 · pp. 1686-1697

Keywords: MUC1, CIN85, protein-protein interaction, cell migration, metastasis, novel targets, glycosylation

Selective anticancer agents suppress aging in Drosophila Research Paper

Anton Danilov, Mikhail Shaposhnikov, Ekaterina Plyusnina, Valeria Kogan, Peter Fedichev, Alexey Moskalev

Published Sep 7, 2013 · Vol. 4, No. 9 · pp. 1507-1526

Keywords: longevity, quality of life, aging-suppressive substances, anticancer agents, PI3K, TOR, iNOS, NF-ÎºB, Drosophila melanogaster

Publication Alerts

European Cancer and Oncology Congress

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Pathways and therapeutic targets in melanoma Review

Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells. Research Paper

PDGFRÎ± up-regulation mediated by Sonic Hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation Research Paper

The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells Research Paper

Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation Research Paper

Eradication of metastatic melanoma through cooperative expression of RNA-based HDAC1 inhibitor and p73 by oncolytic adenovirus Research Paper

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style Research Paper

SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells Research Paper

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Research Paper

Plasticity of melanoma and EMT-TF reprogramming Editorial Materials

Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer. Research Paper

The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model Brief Reports

Chemokines in tumor progression and metastasis Review

Mitochondrial oxidative stress is the achilleâ€™s heel of melanoma cells resistant to Braf-mutant inhibitor Research Paper

Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector Research Paper

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

Selective anticancer agents suppress aging in Drosophila Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Pathways and therapeutic targets in melanoma Review

Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells. Research Paper

PDGFRÎ± up-regulation mediated by Sonic Hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation Research Paper

The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells Research Paper

Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation Research Paper

Eradication of metastatic melanoma through cooperative expression of RNA-based HDAC1 inhibitor and p73 by oncolytic adenovirus Research Paper

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style Research Paper

SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells Research Paper

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Research Paper

Plasticity of melanoma and EMT-TF reprogramming Editorial Materials

Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer. Research Paper

The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model Brief Reports

Chemokines in tumor progression and metastasis Review

Mitochondrial oxidative stress is the achilleâ€™s heel of melanoma cells resistant to Braf-mutant inhibitor Research Paper

Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector Research Paper

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

Selective anticancer agents suppress aging in Drosophila Research Paper