The Oncosearch | Oncotarget

Clinical next generation sequencing to identify actionable aberrations in a phase I program Research Paper

Genevieve M. Boland, Sarina A. Piha-Paul, Vivek Subbiah, Mark Routbort, Shelley M. Herbrich, Keith Baggerly, Keyur P. Patel, Lauren Brusco, Chacha Horombe, Aung Naing, Siqing Fu, David S. Hong, Filip Janku, Amber Johnson, Russell Broaddus, Raja Luthra, Kenna Shaw, John Mendelsohn, Gordon B. Mills, Funda Meric-Bernstam

Published May 8, 2015 · Vol. 6, No. 24 · pp. 20099-20110

The c-Jun/RHOB/AKT pathway confers resistance of BRAF-mutant melanoma cells to MAPK inhibitors Research Paper

Audrey Delmas, Julia Cherier, Magdalena Pohorecka, Claire Medale-Giamarchi, Nicolas Meyer, Anne Casanova, Olivier Sordet, Laurence Lamant, Ariel Savina, Anne Pradines, Gilles Favre

Published May 7, 2015 · Vol. 6, No. 17 · pp. 15250-15264

Absolute quantification of cell-free microRNAs in cancer patients Research Paper

Manuela Ferracin, Laura Lupini, Irene Salamon, Elena Saccenti, Maria Vittoria Zanzi, Andrea Rocchi, Lucia Da Ros, Barbara Zagatti, Gentian Musa, Cristian Bassi, Alessandra Mangolini, Giorgio Cavallesco, Antonio Frassoldati, Stefano Volpato, Paolo Carcoforo, Alan B. Hollingsworth, Massimo Negrini

Published May 2, 2015 · Vol. 6, No. 16 · pp. 14545-14555

miR-514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma Research Paper

Mitchell S. Stark, Vanessa F. Bonazzi, Glen M. Boyle, Jane M. Palmer, Judith Symmons, Catherine M. Lanagan, Christopher W. Schmidt, Adrian C. Herington, Robert Ballotti, Pamela M. Pollock, Nicholas K. Hayward

Published Apr 23, 2015 · Vol. 6, No. 19 · pp. 17753-17763

Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway Research Paper

Nguyen Dinh Thang, Ichiro Yajima, Mayuko Y. Kumasaka, Machiko Iida, Tamio Suzuki, Masashi Kato

Published Apr 20, 2015 · Vol. 6, No. 16 · pp. 14290-14299

Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter Research Paper

Jian-Ge Qiu, Yao-Jun Zhang, Yong Li, Jin-Ming Zhao, Wen-Ji Zhang, Qi-Wei Jiang, Xiao-Long Mei, You-Qiu Xue, Wu-Ming Qin, Yang Yang, Di-Wei Zheng, Yao Chen, Meng-Ning Wei, Zhi Shi

Published Apr 14, 2015 · Vol. 6, No. 17 · pp. 15494-15509

Swiprosin-1 stimulates cancer invasion and metastasis by increasing the Rho family of GTPase signaling Research Paper

Yun Hyun Huh, Sena Oh, Yu Ra Yeo, In Hee Chae, So Hee Kim, Ji Shin Lee, Sook Jung Yun, Kyu Yeong Choi, Je-Hwang Ryu, Chang-Duk Jun, Woo Keun Song

Published Apr 11, 2015 · Vol. 6, No. 15 · pp. 13060-13071

Pregnancy associated plasma protein-A links pregnancy and melanoma progression by promoting cellular migration and invasion Research Paper

Prashanth Prithviraj, Matthew Anaka, Sonja J. McKeown, Michael Permezel, Marzena Walkiewicz, Jonathan Cebon, Andreas Behren, Aparna Jayachandran

Published Apr 10, 2015 · Vol. 6, No. 18 · pp. 15953-15965

Combining TGF-Î²1 knockdown and miR200c administration to optimize antitumor efficacy of B16F10/GPI-IL-21 vaccine Research Paper

Xiaoying Wang, Fengshu Zhao, Xiangfeng He, Jing Wang, Ying Zhang, Hongyi Zhang, Yaoyao Ni, Jianan Sun, Xiaobing Wang, Jun Dou

Published Mar 30, 2015 · Vol. 6, No. 14 · pp. 12493-12504

Molecular stratification of metastatic melanoma using gene expression profiling : Prediction of survival outcome and benefit from molecular targeted therapy Research Paper

Helena Cirenajwis, Henrik Ekedahl, Martin Lauss, Katja Harbst, Ana Carneiro, Jens Enoksson, Frida Rosengren, Linda Werner-Hartman, Therese TÃ¶rngren, Anders Kvist, Erik Fredlund, PÃ¤r-Ola Bendahl, Karin JirstrÃ¶m, Lotta Lundgren, Jillian Howlin, Ã…ke Borg, Sofia K. Gruvberger-Saal, Lao H. Saal, Kari Nielsen, Markus RingnÃ©r, Hensin Tsao, HÃ¥kan Olsson, Christian Ingvar, Johan Staaf, GÃ¶ran JÃ¶nsson

Published Mar 26, 2015 · Vol. 6, No. 14 · pp. 12297-12309

Comparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer? Research Paper

Christiane Margue, Susanne Reinsbach, Demetra Philippidou, Nicolas Beaume, Casandra Walters, Jochen G. Schneider, DorothÃ©e Nashan, Iris Behrmann, Stephanie Kreis

Published Mar 26, 2015 · Vol. 6, No. 14 · pp. 12110-12127

Cisplatin fails to induce puma mediated apoptosis in mucosal melanomas Research Paper

Marie Kristin Fritsche, Veronika Metzler, Karen Becker, Christian Plettenberg, Clemens Heiser, Benedikt Hofauer, Andreas Knopf

Published Mar 26, 2015 · Vol. 6, No. 12 · pp. 9887-9896

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies Clinical Research Papers

Filip Janku, Philipp Angenendt, Apostolia M. Tsimberidou, Siqing Fu, Aung Naing, Gerald S. Falchook, David S. Hong, Veronica R. Holley, Goran Cabrilo, Jennifer J. Wheler, Sarina A. Piha-Paul, Ralph G. Zinner, Agop Y. Bedikian, Michael J. Overman, Bryan K. Kee, Kevin B. Kim, Scott E. Kopetz, Rajyalakshmi Luthra, Frank Diehl, Funda Meric-Bernstam, Razelle Kurzrock

Published Mar 25, 2015 · Vol. 6, No. 14 · pp. 12809-12821

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment Research Paper

Laura R. H. Ip, George Poulogiannis, Felipe Cia Viciano, Junko Sasaki, Satoshi Kofuji, Victoria J. Spanswick, Daniel Hochhauser, John A. Hartley, Takehiko Sasaki, Christina A. Gewinner

Published Mar 24, 2015 · Vol. 6, No. 12 · pp. 10548-10562

Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance Research Paper

Fernando Gallardo, Andreina PadrÃ³n, Ricard Garcia-Carbonell, Cristina Rius, Abel GonzÃ¡lez-Perez, Montserrat ArumÃ-Uria, Mar Iglesias, Lara Nonell, Beatriz Bellosillo, Sonia Segura, Ramon Maria Pujol, Nuria Lopez-Bigas, Joan Bertran, Anna Bigas, LluÃs Espinosa

Published Mar 19, 2015 · Vol. 6, No. 11 · pp. 9284-9294

A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis Research Paper

Liping Xiang, Ting Chi, Qiao Tang, Xiang Yang, Minrui Ou, Xiufen Chen, Xiaobo Yu, Jianzhong Chen, Rodney J.Y. Ho, Jingwei Shao, Lee Jia

Published Mar 19, 2015 · Vol. 6, No. 11 · pp. 9295-9312

Low thyroid hormone levels improve survival in murine model for ocular melanoma Research Paper

Ido Didi Fabian, Mordechai Rosner, Ina Fabian, Vicktoria Vishnevskia-Dai, Ofira Zloto, Elena Shinderman Maman, Keren Cohen, Martin Ellis, Hung-Yun Lin, Aleck Hercbergs, Paul J. Davis, Osnat Ashur-Fabian

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11038-11046

Cordycepin (3â€™-deoxyadenosine) suppressed HMGA2, Twist1 and ZEB1-dependent melanoma invasion and metastasis by targeting miR-33b Research Paper

Pu Zhang, Changjin Huang, Changliang Fu, Yang Tian, Yijuan Hu, Bochu Wang, Amy Strasner, Yang Song, Erqun Song

Published Mar 13, 2015 · Vol. 6, No. 12 · pp. 9834-9853

Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort Clinical Research Papers

JÃ©rÃ©mie Nsengimana, Jon Laye, Anastasia Filia, Christy Walker, Rosalyn Jewell, Joost J. Van den Oord, Pascal Wolter, Poulam Patel, Antje Sucker, Dirk Schadendorf, GÃ¶ran B. JÃ¶nsson, D. Timothy Bishop, Julia Newton-Bishop

Published Mar 12, 2015 · Vol. 6, No. 13 · pp. 11683-11693

Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma Priority Research Paper

Boris Ratnikov, Pedro Aza-Blanc, Zeâ€™ev A. Ronai, Jeffrey W. Smith, Andrei L. Osterman, David A. Scott

Published Feb 28, 2015 · Vol. 6, No. 10 · pp. 7379-7389

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Clinical next generation sequencing to identify actionable aberrations in a phase I program Research Paper

The c-Jun/RHOB/AKT pathway confers resistance of BRAF-mutant melanoma cells to MAPK inhibitors Research Paper

Absolute quantification of cell-free microRNAs in cancer patients Research Paper

miR-514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma Research Paper

Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway Research Paper

Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter Research Paper

Swiprosin-1 stimulates cancer invasion and metastasis by increasing the Rho family of GTPase signaling Research Paper

Pregnancy associated plasma protein-A links pregnancy and melanoma progression by promoting cellular migration and invasion Research Paper

Combining TGF-Î²1 knockdown and miR200c administration to optimize antitumor efficacy of B16F10/GPI-IL-21 vaccine Research Paper

Molecular stratification of metastatic melanoma using gene expression profiling : Prediction of survival outcome and benefit from molecular targeted therapy Research Paper

Comparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer? Research Paper

Cisplatin fails to induce puma mediated apoptosis in mucosal melanomas Research Paper

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies Clinical Research Papers

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment Research Paper

Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance Research Paper

A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis Research Paper

Low thyroid hormone levels improve survival in murine model for ocular melanoma Research Paper

Cordycepin (3â€™-deoxyadenosine) suppressed HMGA2, Twist1 and ZEB1-dependent melanoma invasion and metastasis by targeting miR-33b Research Paper

Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort Clinical Research Papers

Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Clinical next generation sequencing to identify actionable aberrations in a phase I program Research Paper

The c-Jun/RHOB/AKT pathway confers resistance of BRAF-mutant melanoma cells to MAPK inhibitors Research Paper

Absolute quantification of cell-free microRNAs in cancer patients Research Paper

miR-514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma Research Paper

Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway Research Paper

Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter Research Paper

Swiprosin-1 stimulates cancer invasion and metastasis by increasing the Rho family of GTPase signaling Research Paper

Pregnancy associated plasma protein-A links pregnancy and melanoma progression by promoting cellular migration and invasion Research Paper

Combining TGF-Î²1 knockdown and miR200c administration to optimize antitumor efficacy of B16F10/GPI-IL-21 vaccine Research Paper

Molecular stratification of metastatic melanoma using gene expression profiling : Prediction of survival outcome and benefit from molecular targeted therapy Research Paper

Comparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer? Research Paper

Cisplatin fails to induce puma mediated apoptosis in mucosal melanomas Research Paper

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies Clinical Research Papers

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment Research Paper

Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance Research Paper

A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis Research Paper

Low thyroid hormone levels improve survival in murine model for ocular melanoma Research Paper

Cordycepin (3â€™-deoxyadenosine) suppressed HMGA2, Twist1 and ZEB1-dependent melanoma invasion and metastasis by targeting miR-33b Research Paper

Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort Clinical Research Papers

Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma Priority Research Paper