The Oncosearch | Oncotarget

Classification of current anticancer immunotherapies Review

Lorenzo Galluzzi, Erika Vacchelli, JosÃ©-Manuel Bravo-San Pedro, Aitziber BuquÃ©, Laura Senovilla, Elisa Elena Baracco, Norma Bloy, Francesca Castoldi, Jean-Pierre Abastado, Patrizia Agostinis, Ron N. Apte, Fernando Aranda, Maha Ayyoub, Philipp Beckhove, Jean-Yves Blay, Laura Bracci, Anne Caignard, Chiara Castelli, Federica Cavallo, Estaban Celis, Vincenzo Cerundolo, Aled Clayton, Mario P. Colombo, Lisa Coussens, Madhav V. Dhodapkar, Alexander M. Eggermont, Douglas T. Fearon, Wolf H. Fridman, Jitka FuÄÃkovÃ¡, Dmitry I. Gabrilovich, JÃ©rÃ´me Galon, Abhishek Garg, FranÃ§ois Ghiringhelli, Giuseppe Giaccone, Eli Gilboa, Sacha Gnjatic, Axel Hoos, Anne Hosmalin, Dirk JÃ¤ger, Pawel Kalinski, Klas KÃ¤rre, Oliver Kepp, Rolf Kiessling, John M. Kirkwood, Eva Klein, Alexander Knuth, Claire E. Lewis, Roland Liblau, Michael T. Lotze, Enrico Lugli, Jean-Pierre Mach, Fabrizio Mattei, Domenico Mavilio, Ignacio Melero, Cornelis J. Melief, Elizabeth A. Mittendorf, Lorenzo Moretta, Adekunke Odunsi, Hideho Okada, Anna Karolina Palucka, Marcus E. Peter, Kenneth J. Pienta, Angel Porgador, George C. Prendergast, Gabriel A. Rabinovich, Nicholas P. Restifo, Naiyer Rizvi, Catherine SautÃ¨s-Fridman, Hans Schreiber, Barbara Seliger, Hiroshi Shiku, Bruno Silva-Santos, Mark J. Smyth, Daniel E. Speiser, Radek Spisek, Pramod K. Srivastava, James E. Talmadge, Eric Tartour, Sjoerd H. Van Der Burg, BenoÃ®t J. Van Den Eynde, Richard Vile, Hermann Wagner, JeffreyÂ S. Weber, Theresa L. Whiteside, Jedd D. Wolchok, Laurence Zitvogel, Weiping Zou, Guido Kroemer

Published Dec 18, 2014 · Vol. 5, No. 24 · pp. 12472-12508

The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis Research Paper

Jade Peres, Shaheen Mowla, Sharon Prince

Published Dec 16, 2014 · Vol. 6, No. 3 · pp. 1821-1833

Keywords: TBX3, AKT3, melanoma, E-cadherin, T-box factors.

Clinically relevant genes and regulatory pathways associated with NRAS^Q61 mutations in melanoma through an integrative genomics approach Research Paper

Wei Jiang, Peilin Jia, Katherine E. Hutchinson, Douglas B. Johnson, Jeffrey A. Sosman, Zhongming Zhao

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2496-2508

Targeting the microRNA-21/AP1 axis by 5-fluorouracil and pirarubicin in human hepatocellular carcinoma Research Paper

Xiaodong He, Jingjing Li, Weidong Guo, Wei Liu, Jia Yu, Wei Song, Lei Dong, Fang Wang, Shuangni Yu, Yi Zheng, Songsen Chen, Yan Kong, Changzheng Liu

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2302-2314

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma Research Paper

Stephen Q. Wong, Andreas Behren, Victoria J. Mar, Katherine Woods, Jason Li, Claire Martin, Karen E. Sheppard, Rory Wolfe, John Kelly, Jonathan Cebon, Alexander Dobrovic, Grant A. McArthur

Published Dec 6, 2014 · Vol. 6, No. 2 · pp. 1115-1127

Keywords: Melanoma, RQCD1, exome sequencing

Norepinephrine promotes tumor microenvironment reactivity through Î²3-adrenoreceptors during melanoma progression Research Paper

Maura Calvani, Floriane Pelon, Giuseppina Comito, Maria Letizia Taddei, Silvia Moretti, Stefania Innocenti, Romina Nassini, Gianni Gerlini, Lorenzo Borgognoni, Franco Bambi, Elisa Giannoni, Luca Filippi, Paola Chiarugi

Published Dec 1, 2014 · Vol. 6, No. 7 · pp. 4615-4632

Keywords: Î²-adrenergic receptors, melanoma, tumor microenvironment, cancer associated fibroblasts, macrophages, mesenchymal stem cells

Oncotargeting G proteins: The Hippo in the room Research Perspective

Xiaodong Feng, Qianming Chen, J. Silvio Gutkind

Published Nov 25, 2014 · Vol. 5, No. 22 · pp. 10997-10999

Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer Research Paper

Igor Vujic, Martina Sanlorenzo, Christian Posch, Rosaura Esteve-Puig, Adam J. Yen, Andrew Kwong, Aaron Tsumura, Ryan Murphy, Klemens Rappersberger, Susana Ortiz-Urda

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 969-978

Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma Review

Francesco Spagnolo, Paola Ghiorzo, Paola Queirolo

Published Nov 15, 2014 · Vol. 5, No. 21 · pp. 10206-10221

B-Raf inhibitor vemurafenib in combination with temozolomide and fotemustine in the killing response of malignant melanoma cells Research Paper

Wynand P. Roos, Steve Quiros, Andrea Krumm, Stephanie Merz, Olivier JÃ©rÃ´me Switzeny, Markus Christmann, Carmen Loquai, Bernd Kaina

Published Oct 21, 2014 · Vol. 5, No. 24 · pp. 12607-12620

Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells Research Paper

Yi Lun Liu, Fritz Lai, James S. Wilmott, Xu Guang Yan, Xiao Ying Liu, Qi Luan, Su Tang Guo, Chen Chen Jiang, Hsin-Yi Tseng, Richard A. Scolyer, Lei Jin, Xu Dong Zhang

Published Oct 21, 2014 · Vol. 5, No. 22 · pp. 11237-11251

Angiostatic, tumor inflammatory and anti-tumor effects of CXCL447-70 and CXCL4L147-70 in an EGF-dependent breast cancer model Research Paper

Katrien Van Raemdonck, Nele Berghmans, Vincent Vanheule, Antonella Bugatti, Paul Proost, Ghislain Opdenakker, Marco Presta, Jo Van Damme, Sofie Struyf

Published Oct 21, 2014 · Vol. 5, No. 21 · pp. 10916-10933

Keywords: CXCL4, CXCL4L1, EGF, CCL5, angiogenesis

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications Review

Eftychia Oikonomou, Evangelos Koustas, Maria Goulielmaki, Alexander Pintzas

Published Oct 21, 2014 · Vol. 5, No. 23 · pp. 11752-11777

Signaling pathways activation profiles make better markers of cancer than expression of individual genes Research Paper

Nikolay M. Borisov, Nadezhda V. Terekhanova, Alexander M. Aliper, Larisa S. Venkova, Philip Yu Smirnov, Sergey Roumiantsev, Mikhail B. Korzinkin, Alex A. Zhavoronkov, Anton A. Buzdin

Published Oct 13, 2014 · Vol. 5, No. 20 · pp. 10198-10205

Down-regulation of miRNA-106b inhibits growth of melanoma cells by promoting G1-phase cell cycle arrest and reactivation of p21/WAF1/Cip1 protein Research Paper

Ram Prasad, Santosh K. Katiyar

Published Sep 25, 2014 · Vol. 5, No. 21 · pp. 10636-10649

Regulation of NADPH-dependent Nitric Oxide and reactive oxygen species signalling in endothelial and melanoma cells by a photoactive NADPH analogue Research Paper

Florian Rouaud, Miguel Romero-Perez, Huan Wang, Irina Lobysheva, Booma Ramassamy, Etienne Henry, Patrick Tauc, Damien Giacchero, Jean-Luc Boucher, Eric Deprez, StÃ©phane Rocchi, Anny Slama-Schwok

Published Sep 25, 2014 · Vol. 5, No. 21 · pp. 10650-10664

TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells Research Paper

Selina K. Sutton, Jessica Koach, Owen Tan, Bing Liu, Daniel R. Carter, James S. Wilmott, Benafsha Yosufi, Lauren E. Haydu, Graham J. Mann, John F. Thompson, Georgina V. Long, Tao Liu, Grant McArthur, Xu Dong Zhang, Richard A. Scolyer, Belamy B. Cheung, Glenn M. Marshall

Published Sep 20, 2014 · Vol. 5, No. 20 · pp. 10127-10139

Keywords: Melanoma, TRIM16, BRAF inhibitor, cell migration, IFNÎ²1

Melanoma-initiating cells exploit M2 macrophage TGFÎ² and arginase pathway for survival and proliferation Research Paper

Muly Tham, Kar Wai Tan, Jo Keeble, Xiaojie Wang, Sandra Hubert, Luke Barron, Nguan Soon Tan, Masashi Kato, Armelle Prevost-Blondel, Veronique Angeli, Jean-Pierre Abastado

Published Sep 16, 2014 · Vol. 5, No. 23 · pp. 12027-12042

Melanoma patient-derived xenografts accurately model the disease and develop fast enough to guide treatment decisions Clinical Research Papers

Berglind O. Einarsdottir, Roger Olofsson Bagge, Joydeep Bhadury, Henrik Jespersen, Jan Mattsson, Lisa M. Nilsson, Katarina TruvÃ©, Marcela DÃ¡vila LÃ³pez, Peter Naredi, Ola Nilsson, Ulrika Stierner, Lars Ny, Jonas A. Nilsson

Published Sep 8, 2014 · Vol. 5, No. 20 · pp. 9609-9618

miR-524-5p suppresses the growth of oncogenic BRAF melanoma by targeting BRAF and ERK2 Research Paper

Szu-Mam Liu, Jean Lu, Hoong-Chien Lee, Feng-Hsiang Chung, Nianhan Ma

Published Sep 8, 2014 · Vol. 5, No. 19 · pp. 9444-9459

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Classification of current anticancer immunotherapies Review

The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis Research Paper

Clinically relevant genes and regulatory pathways associated with NRAS^Q61 mutations in melanoma through an integrative genomics approach Research Paper

Targeting the microRNA-21/AP1 axis by 5-fluorouracil and pirarubicin in human hepatocellular carcinoma Research Paper

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma Research Paper

Norepinephrine promotes tumor microenvironment reactivity through Î²3-adrenoreceptors during melanoma progression Research Paper

Oncotargeting G proteins: The Hippo in the room Research Perspective

Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer Research Paper

Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma Review

B-Raf inhibitor vemurafenib in combination with temozolomide and fotemustine in the killing response of malignant melanoma cells Research Paper

Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells Research Paper

Angiostatic, tumor inflammatory and anti-tumor effects of CXCL447-70 and CXCL4L147-70 in an EGF-dependent breast cancer model Research Paper

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications Review

Signaling pathways activation profiles make better markers of cancer than expression of individual genes Research Paper

Down-regulation of miRNA-106b inhibits growth of melanoma cells by promoting G1-phase cell cycle arrest and reactivation of p21/WAF1/Cip1 protein Research Paper

Regulation of NADPH-dependent Nitric Oxide and reactive oxygen species signalling in endothelial and melanoma cells by a photoactive NADPH analogue Research Paper

TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells Research Paper

Melanoma-initiating cells exploit M2 macrophage TGFÎ² and arginase pathway for survival and proliferation Research Paper

Melanoma patient-derived xenografts accurately model the disease and develop fast enough to guide treatment decisions Clinical Research Papers

miR-524-5p suppresses the growth of oncogenic BRAF melanoma by targeting BRAF and ERK2 Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Classification of current anticancer immunotherapies Review

The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis Research Paper

Clinically relevant genes and regulatory pathways associated with NRASQ61 mutations in melanoma through an integrative genomics approach Research Paper

Targeting the microRNA-21/AP1 axis by 5-fluorouracil and pirarubicin in human hepatocellular carcinoma Research Paper

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma Research Paper

Norepinephrine promotes tumor microenvironment reactivity through Î²3-adrenoreceptors during melanoma progression Research Paper

Oncotargeting G proteins: The Hippo in the room Research Perspective

Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer Research Paper

Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma Review

B-Raf inhibitor vemurafenib in combination with temozolomide and fotemustine in the killing response of malignant melanoma cells Research Paper

Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells Research Paper

Angiostatic, tumor inflammatory and anti-tumor effects of CXCL447-70 and CXCL4L147-70 in an EGF-dependent breast cancer model Research Paper

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications Review

Signaling pathways activation profiles make better markers of cancer than expression of individual genes Research Paper

Down-regulation of miRNA-106b inhibits growth of melanoma cells by promoting G1-phase cell cycle arrest and reactivation of p21/WAF1/Cip1 protein Research Paper

Regulation of NADPH-dependent Nitric Oxide and reactive oxygen species signalling in endothelial and melanoma cells by a photoactive NADPH analogue Research Paper

TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells Research Paper

Melanoma-initiating cells exploit M2 macrophage TGFÎ² and arginase pathway for survival and proliferation Research Paper

Melanoma patient-derived xenografts accurately model the disease and develop fast enough to guide treatment decisions Clinical Research Papers

miR-524-5p suppresses the growth of oncogenic BRAF melanoma by targeting BRAF and ERK2 Research Paper

Clinically relevant genes and regulatory pathways associated with NRAS^Q61 mutations in melanoma through an integrative genomics approach Research Paper