The Oncosearch | Oncotarget

Targeting the K-Ras - JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation Research Paper

Masashi Okada, Keita Shibuya, Atsushi Sato, Shizuka Seino, Shuhei Suzuki, Manabu Seino, Chifumi Kitanaka

Published Jun 10, 2014 · Vol. 5, No. 13 · pp. 5100-5112

Insights from yeast into whether the rapamycin inhibition of heat shock transcription factor (Hsf1) can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor Research Paper

Stefan H. Millson, Peter W. Piper

Published Jun 7, 2014 · Vol. 5, No. 13 · pp. 5054-5064

The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase Research Paper

Martina Olivero, Daniela Dettori, Sabrina Arena, Davide Zecchin, Erica Lantelme, Maria Flavia Di Renzo

Published May 30, 2014 · Vol. 5, No. 15 · pp. 5992-6002

PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia Research Paper

Parama Dey, Satyanarayana Rachagani, Arokia P. Vaz, Moorthy P. Ponnusamy, Surinder K. Batra

Published May 30, 2014 · Vol. 5, No. 12 · pp. 4480-4491

Loss of EGFR signaling-regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance Research Paper

Man Kit Siu, Wassim Abou-Kheir, Juan Juan Yin, Yung-Sheng Chang, Ben Barrett, Florent Suau, Orla Casey, Wei-Yu Chen, Lei Fang, Paul Hynes, Yao-Yu Hsieh, Yen-Nien Liu, Jiaoti Huang, Kathleen Kelly

Published May 20, 2014 · Vol. 5, No. 11 · pp. 3770-3784

Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme Research Paper

Anna Laurenzana, Alessio Biagioni, Silvia Dâ€™Alessio, Francesca Bianchini, Anastasia ChillÃ, Francesca Margheri, Cristina Luciani, Benedetta Mazzanti, Nicola Pimpinelli, Eugenio Torre, Silvio Danese, Lido Calorini, Mario Del Rosso, Gabriella Fibbi

Published May 19, 2014 · Vol. 5, No. 11 · pp. 3711-3727

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma Research Paper

Kathleen M. Capaccione, Xuehui Hong, Katherine M. Morgan, Wenyu Liu, Michael J. Bishop, LianXin Liu, Elke Markert, Malik Deen, Christine Minerowicz, Thaddeus Allen, Sharon R. Pine

Published May 19, 2014 · Vol. 5, No. 11 · pp. 3636-3650

The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors Research Paper

Bhaskar Kahali, Jinlong Yu, Stefanie B. Marquez, Kenneth W. Thompson, Shermi Y. Liang, Li Lu, David Reisman

Published May 4, 2014 · Vol. 5, No. 10 · pp. 3316-3332

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-ÎºB-dependent activation of Snail Research Paper

Magdalena A. Cichon, Derek C. Radisky

Published May 1, 2014 · Vol. 5, No. 9 · pp. 2827-2838

The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells Research Paper

Timothy S. Pardee, Kristin Stadelman, Jamie Jennings-Gee, David L. Caudell, William H. Gmeiner

Published May 1, 2014 · Vol. 5, No. 12 · pp. 4170-4179

Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration Research Paper

Amelie Hailer, Thomas GP Grunewald, Martin Orth, Cora Reiss, Burkhard Kneitz, Martin Spahn, Elke Butt

Published Apr 27, 2014 · Vol. 5, No. 12 · pp. 4144-4153

Rad51 supports triple negative breast cancer metastasis. Research Paper

Adrian P. Wiegmans, Fares Al-Ejeh, Nicole Chee, Pei-Yi Yap, Julia J. Gorski, Leonard Da Silva, Emma Bolderson, Georgia Chenevix-Trench, Robin Anderson, Peter T. Simpson, Sunil R. Lakhani, Kum Kum Khanna

Published Apr 27, 2014 · Vol. 5, No. 10 · pp. 3261-3272

Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy Research Paper

Rachel Abbotts, Rosalyn Jewell, JÃ©rÃ©mie Nsengimana, David J. Maloney, Anton Simeonov, Claire Seedhouse, Faye Elliott, Jon Laye, Christy Walker, Ajit Jadhav, Anna Grabowska, Graham Ball, Poulam M. Patel, Julia Newton-Bishop, David M. Wilson III, Srinivasan Madhusudan

Published Apr 27, 2014 · Vol. 5, No. 10 · pp. 3273-3286

Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma Research Paper

Ming-Huang Chen, Kun-Chun Chiang, Chi-Tung Cheng, Shih-Chiang Huang, Yeng-Yang Chen, Tsung-Wen Chen, Ta-Sen Yeh, Yi-Yin Jan, Hsi-Ming Wang, Jiang-Jie Weng, Peter Mu-Hsin Chang, Chun-Yu Liu, Chung-Pin Li, Yee Chao, Ming-Han Chen, Chi-Ying F. Huang, Chun-Nan Yeh

Published Mar 26, 2014 · Vol. 5, No. 9 · pp. 2372-2389

Keywords: NVP-AUY922, NVP-BEZ235, heat-shock protein 90, phosphatase and tensin homolog

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor Research Paper

Koichi Azuma, Akihiko Kawahara, Kahori Sonoda, Kazutaka Nakashima, Kousuke Tashiro, Kosuke Watari, Hiroto Izumi, Masayoshi Kage, Michihiko Kuwano, Mayumi Ono, Tomoaki Hoshino

Published Mar 26, 2014 · Vol. 5, No. 15 · pp. 5908-5919

Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis Research Paper

Mourad Sanhaji, Andreas Ritter, Hannah R. Belsham, Claire T. Friel, Susanne Roth, Frank Louwen, Juping Yuan

Published Mar 24, 2014 · Vol. 5, No. 10 · pp. 3130-3144

Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth Research Paper

Audrey Vincent, Seung-Mo Hong, Chaoxin Hu, Noriyuki Omura, Angela Young, Haeryoung Kim, Jun Yu, Spencer Knight, Michael Ayars, Margaret Griffith, Isabelle Van Seuningen, Anirban Maitra, Michael Goggins

Published Mar 22, 2014 · Vol. 5, No. 9 · pp. 2575-2587

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

Jinquan Cai, Pei Yang, Chuanbao Zhang, Wei Zhang, Yanwei Liu, Zhaoshi Bao, Xing Liu, Wenzhong Du, Hongjun Wang, Tao Jiang, Chuanlu Jiang

Published Mar 21, 2014 · Vol. 5, No. 9 · pp. 2551-2561

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

Harriet Wikman, Laura Westphal, Felicitas Schmid, Sirkku Pollari, Jolanthe Kropidlowski, Bettina Sielaff-Frimpong, Markus Glatzel, Jakob Matschke, Manfred Westphal, Kristiina Iljin, Heini Huhtala, Luigi Terracciano, Anne Kallioniemi, Guido Sauter, Volkmar MÃ¼ller, Isabell Witzel, Katrin Lamszus, Dirk Kemming, Klaus Pantel

Published Mar 16, 2014 · Vol. 5, No. 10 · pp. 3076-3087

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway Research Paper

Jennifer J. Wheler, Stacy L. Moulder, Aung Naing, Filip Janku, Sarina A. Piha-Paul, Gerald S. Falchook, Ralph Zinner, Apostolia M. Tsimberidou, Siqing Fu, David S. Hong, Johnique T. Atkins, Roman Yelensky, Philip J. Stephens, Razelle Kurzrock

Published Mar 14, 2014 · Vol. 5, No. 10 · pp. 3029-3038

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Targeting the K-Ras - JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation Research Paper

Insights from yeast into whether the rapamycin inhibition of heat shock transcription factor (Hsf1) can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor Research Paper

The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase Research Paper

PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia Research Paper

Loss of EGFR signaling-regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance Research Paper

Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme Research Paper

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma Research Paper

The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors Research Paper

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-ÎºB-dependent activation of Snail Research Paper

The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells Research Paper

Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration Research Paper

Rad51 supports triple negative breast cancer metastasis. Research Paper

Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy Research Paper

Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma Research Paper

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor Research Paper

Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis Research Paper

Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth Research Paper

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeting the K-Ras - JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation Research Paper

Insights from yeast into whether the rapamycin inhibition of heat shock transcription factor (Hsf1) can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor Research Paper

The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase Research Paper

PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia Research Paper

Loss of EGFR signaling-regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance Research Paper

Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme Research Paper

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma Research Paper

The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors Research Paper

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-ÎºB-dependent activation of Snail Research Paper

The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells Research Paper

Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration Research Paper

Rad51 supports triple negative breast cancer metastasis. Research Paper

Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy Research Paper

Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma Research Paper

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor Research Paper

Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis Research Paper

Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth Research Paper

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway Research Paper