The Oncosearch | Oncotarget

TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

Fangfang Bu, Xing Liu, Jingjing Li, Shukun Chen, Xin Tong, Chunsheng Ma, Hui Mao, Fei Pan, Xiaoyan Li, Bo Chen, Liyan Xu, Enmin Li, Geng Kou, Jun Han, Shangjing Guo, Jian Zhao, Yajun Guo

Published Dec 3, 2014 · Vol. 6, No. 4 · pp. 2120-2133

Loss of p21^Cip1/CDKN1A renders cancer cells susceptible to Polo-like kinase 1 inhibition Research Paper

Nina-Naomi Kreis, Frank Louwen, Brigitte Zimmer, Juping Yuan

Published Dec 2, 2014 · Vol. 6, No. 9 · pp. 6611-6626

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

Soo Jung Kim, Kyung Hee Jung, Hong Hua Yan, Mi Kwon Son, Zhenghuan Fang, Ye-Lim Ryu, Hyunseung Lee, Joo Han Lim, Jun-Kyu Suh, JinHee Kim, Soyoung Lee, Sungwoo Hong, Soon-Sun Hong

Published Dec 2, 2014 · Vol. 6, No. 3 · pp. 1507-1518

Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP Research Paper

Davide Esposito, Elvira Crescenzi, Vinay Sagar, Fabrizio Loreni, Annapina Russo, Giulia Russo

Published Nov 28, 2014 · Vol. 5, No. 22 · pp. 11737-11751

Keywords: p21, ribosomal protein, 5-FU, Oxaliplatin, DNA repair

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper

Schammim Ray Amith, Jodi Marie Wilkinson, Shairaz Baksh, Larry Fliegel

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1262-1275

TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer Research Paper

JosÃ© A. GalvÃ¡n, Melina Helbling, Viktor H. Koelzer, Mario P. Tschan, Martin D. Berger, Marion HÃ¤drich, Beat SchnÃ¼riger, Eva Karamitopoulou, Heather Dawson, Daniel Inderbitzin, Alessandro Lugli, Inti Zlobec

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 874-885

Keywords: tumor microenvironment, methylation, budding, pyrosequencing, Twist

Higher mortality and impaired elimination of bacteria in aged mice after intracerebral infection with E. coli are associated with an age-related decline of microglia and macrophage functions Research Paper

Sandra SchÃ¼tze, Sandra Ribes, Annika Kaufmann, Anja Manig, JÃ¶rg Scheffel, Sandra Redlich, Stephanie Bunkowski, Uwe-Karsten Hanisch, Wolfgang BrÃ¼ck, Roland Nau

Published Nov 26, 2014 · Vol. 5, No. 24 · pp. 12573-12592

Keywords: aging, bacterial CNS infection, E. coli, microglia, macrophages, phagocytosis, innate immunity.

Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss Research Paper

Rafaela Andrade-Vieira, Donna Goguen, Heidi A. Bentley, Chris V. Bowen, Paola A. Marignani

Published Nov 25, 2014 · Vol. 5, No. 24 · pp. 12738-12752

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors Research Paper

Ming Xu, Changhong Zhu, Xian Zhao, Cheng Chen, Hailong Zhang, Haihua Yuan, Rong Deng, Jinzhuo Dou, Yanli Wang, Jian Huang, Qin Chen, Bin Jiang, Jianxiu Yu

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 979-994

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer Research Paper

Anna Chen, Christina S.F. Wong, Mira C.P. Liu, Colin M. House, Jaclyn Sceneay, David D. Bowtell, Erik W. Thompson, Andreas MÃ¶ller

Published Nov 18, 2014 · Vol. 6, No. 2 · pp. 862-873

Loss of compensatory pro-survival and anti-apoptotic modulator, IKKÎµ, sensitizes ovarian cancer cells to CHEK1 loss through an increased level of p21 Research Paper

Marianne K. Kim, Dong J. Min, George Wright, Ian Goldlust, Christina M. Annunziata

Published Nov 15, 2014 · Vol. 5, No. 24 · pp. 12788-12802

Keywords: shRNAs, therapeutic targets, IKKï¥, CHEK1, p21, ovarian cancer

Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle Research Paper

Francesca Pretto, Carmen Ghilardi, Michele Moschetta, Andrea Bassi, Alessandra Rovida, Valentina Scarlato, Laura Talamini, Fabio Fiordaliso, Cinzia Bisighini, Giovanna Damia, Maria Rosa Bani, Rosanna Piccirillo, Raffaella Giavazzi

Published Nov 15, 2014 · Vol. 6, No. 5 · pp. 3043-3054

Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat Research Perspective

Kangxing Song, Shuxia Wang, Mitra Mani, Arya Mani

Published Nov 15, 2014 · Vol. 5, No. 22 · pp. 11000-11003

Human recombinant truncated RNASET2, devoid of RNase activity; A potential cancer therapeutic agent Research Paper

Liron Nesiel-Nuttman, Betty Schwartz, Oded Shoseyov

Published Nov 11, 2014 · Vol. 5, No. 22 · pp. 11464-11478

Metformin and erlotinib synergize to inhibit basal breast cancer Research Paper

Ying-Ka Ingar Lau, Xing Du, Vinayak Rayannavar, Benjamin Hopkins, Jacquelyn Shaw, Eliana Bessler, Tiffany Thomas, Maira M. Pires, Megan Keniry, Ramon E. Parsons, Serge Cremers, Matthias Szabolcs, Matthew A. Maurer

Published Nov 4, 2014 · Vol. 5, No. 21 · pp. 10503-10517

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

Anna Berg, Erling A. Hoivik, Siv MjÃ¸s, Frederik Holst, Henrica M. J. Werner, Ingvild L. Tangen, Amaro Taylor-Weiner, William J. Gibson, Kanthida Kusonmano, Elisabeth Wik, Jone Trovik, Mari K. Halle, Anne M. Ã˜yan, Karl-Henning Kalland, Andrew D. Cherniack, Rameen Beroukhim, Ingunn Stefansson, Gordon B. Mills, Camilla Krakstad, Helga B. Salvesen

Published Nov 4, 2014 · Vol. 6, No. 2 · pp. 1327-1339

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

Dong Hyun Jo, Jin Hyoung Kim, Chang Sik Cho, Young-Lai Cho, Hyoung Oh Jun, Young Suk Yu, Jeong-Ki Min, Jeong Hun Kim

Published Nov 3, 2014 · Vol. 5, No. 22 · pp. 11513-11525

Keywords: Retinoblastoma, STAT3 transcription factor, miR-17-92

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis Research Paper

Catherine E. Waters, Joshua C. Saldivar, Zaynab A. Amin, Morgan S. Schrock, Kay Huebner

Published Oct 31, 2014 · Vol. 6, No. 5 · pp. 3409-3419

Keywords: FHIT, replication stress, DNA double strand breaks, APOBEC deaminase, mutations

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience Clinical Research Papers

Ming-Mo Hou, Xiaochun Liu, Jennifer Wheler, Aung Naing, David Hong, Robert L. Coleman, Apostolia Tsimberidou, Filip Janku, Ralph Zinner, Karen Lu, Razelle Kurzrock, Siqing Fu

Published Oct 29, 2014 · Vol. 5, No. 22 · pp. 11168-11179

Prognostic significance of catalase expression and its regulatory effects on hepatitis B virus X protein (HBx) in HBV-related advanced hepatocellular carcinomas Research Paper

Mi-Young Cho, Jae Youn Cheong, Wonchung Lim, Sujin Jo, Youngsoo Lee, Hee-Jung Wang, Kyou-Hoon Han, Hyeseong Cho

Published Oct 24, 2014 · Vol. 5, No. 23 · pp. 12233-12246

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TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

Loss of p21^Cip1/CDKN1A renders cancer cells susceptible to Polo-like kinase 1 inhibition Research Paper

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP Research Paper

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper

TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer Research Paper

Higher mortality and impaired elimination of bacteria in aged mice after intracerebral infection with E. coli are associated with an age-related decline of microglia and macrophage functions Research Paper

Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss Research Paper

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors Research Paper

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer Research Paper

Loss of compensatory pro-survival and anti-apoptotic modulator, IKKÎµ, sensitizes ovarian cancer cells to CHEK1 loss through an increased level of p21 Research Paper

Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle Research Paper

Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat Research Perspective

Human recombinant truncated RNASET2, devoid of RNase activity; A potential cancer therapeutic agent Research Paper

Metformin and erlotinib synergize to inhibit basal breast cancer Research Paper

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis Research Paper

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience Clinical Research Papers

Prognostic significance of catalase expression and its regulatory effects on hepatitis B virus X protein (HBx) in HBV-related advanced hepatocellular carcinomas Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

Loss of p21Cip1/CDKN1A renders cancer cells susceptible to Polo-like kinase 1 inhibition Research Paper

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP Research Paper

The Na+/H+ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper

TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer Research Paper

Higher mortality and impaired elimination of bacteria in aged mice after intracerebral infection with E. coli are associated with an age-related decline of microglia and macrophage functions Research Paper

Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss Research Paper

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors Research Paper

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer Research Paper

Loss of compensatory pro-survival and anti-apoptotic modulator, IKKÎµ, sensitizes ovarian cancer cells to CHEK1 loss through an increased level of p21 Research Paper

Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle Research Paper

Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat Research Perspective

Human recombinant truncated RNASET2, devoid of RNase activity; A potential cancer therapeutic agent Research Paper

Metformin and erlotinib synergize to inhibit basal breast cancer Research Paper

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis Research Paper

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience Clinical Research Papers

Prognostic significance of catalase expression and its regulatory effects on hepatitis B virus X protein (HBx) in HBV-related advanced hepatocellular carcinomas Research Paper

Loss of p21^Cip1/CDKN1A renders cancer cells susceptible to Polo-like kinase 1 inhibition Research Paper

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells Research Paper