The Oncosearch | Oncotarget

HOXA11 hypermethylation is associated with progression of non-small cell lung cancer Research Paper

Jung-Ah Hwang, Bo Bin Lee, Yujin Kim, Seong-Eun Park, Kyun Heo, Seung-Hyun Hong, Young-Ho Kim, Joungho Han, Duk-Hwan Kim, Young Mog Shim, Yeon-Su Lee

Published Oct 28, 2013 · Vol. 4, No. 12 · pp. 2317-2325

Keywords: HOXA11, Hypermethylation, Non-small cell lung cancer, Progression, Migration

ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer Research Paper

Christian Holzmann, Tatiana Kilch, Sven Kappel, Andrea ArmbrÃ¼ster, Volker Jung, Michael StÃ¶ckle, Ivan Bogeski, Eva C Schwarz, Christine Peinelt

Published Oct 28, 2013 · Vol. 4, No. 11 · pp. 2096-2107

Keywords: Membrane androgen receptor, Orai channel, CRAC channel, prostate cancer, Ca2+ signaling

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Jing Liu, Aimin Xu, Karen Siu-Ling Lam, Nai-Sum Wong, Jie Chen, Peter R R Shepherd, Yu Wang

Published Oct 1, 2013 · Vol. 4, No. 10 · pp. 1804-1818

Keywords: Adiponectin, breast cancer, autophagy, cholesterol, LDLR

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX Research Paper

Marissa V Powers, Melanie Valenti, Susana Mirander, Alison Maloney, Suzanne A Eccles, George Thomas, Paul A Clarke, Paul Workman

Published Sep 29, 2013 · Vol. 4, No. 11 · pp. 1963-1975

Keywords: 17-AAG, HSP90, BAX, Apoptosis, Colon cancer

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine. Research Paper

Sevin Turcan, Armida WM Fabius, Alexandra Borodovsky, Alicia Pedraza, Cameron Brennan, Jason Huse, Agnes Viale, Gregory J Riggins, Timothy A Chan

Published Sep 16, 2013 · Vol. 4, No. 10 · pp. 1729-1736

Keywords: IDH, glioma, decitabine, DNMT

Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice Research Paper

Marianna L Ianzano, Stefania Croci, Giordano Nicoletti, Arianna Palladini, Lorena Landuzzi, Valentina Grosso, Dario Ranieri, Massimiliano Dall'Ora, Ilaria Santeramo, Milena Urbini, Carla De Giovanni, Pier Luigi Lollini, Patrizia Nanni

Published Aug 6, 2013 · Vol. 5, No. 1 · pp. 108-119

Keywords: rhabdomyosarcoma, p53, HER-2, p19Arf, p21Cip1

Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma Multiforme through de-repression of Bcl-xL translation Research Paper

Urszula Liwak, Lindsay E Jordan, Sally Davidson Von-Holt, Poonam Singh, Jennifer E. L. Hanson, Ian A Lorimer, Federico Roncaroli, Martin Holcik

Published Jul 28, 2013 · Vol. 4, No. 9 · pp. 1365-1372

Keywords: Glioblastoma multiforme, Bcl-xL, PDCD4, ABT-737, translation initiation

PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1 Research Paper

Alexander Gont, Jennifer E. L. Hanson, Sylvie J. Lavictoire, Doris A. E. Parolin, Manijeh Daneshmand, Ian J. restall, Mathieu Soucie, Garth Nicholas, John Woulfe, Amin Kassam, Vasco F. Da Silva, Ian A. J. Lorimer

Published Jul 21, 2013 · Vol. 4, No. 8 · pp. 1266-1279

Keywords: glioblastoma, glioma, PTEN, atypical PKC, Lgl, tumor initiating cell

Battle of the eternal rivals: restoring functional p53 and inhibiting Polo-like kinase 1 as cancer therapy Review

Frank Louwen, Juping Yuan

Published Jul 13, 2013 · Vol. 4, No. 7 · pp. 958-971

Keywords: Polo-like kinase 1, p53, Plk1 inhibitor

The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes. Research Paper

William J. Fredericks, Jorge Sepulveda, Priti Lal, John E. Tomaszewski, Ming-Fong Lin, Terry McGarvey, Frank J. Rauscher III, S. Bruce Malkowicz

Published Jul 7, 2013 · Vol. 4, No. 7 · pp. 1075-1092

Keywords: TERE1, UBIAD1, prostate cancer, castrate resistant prostate cancer, CRPC, LnCaP, cholesterol, SXR, androgen catabolism, Vitamin K-2

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

Yunyun Jiang, Filip Janku, Vivek Subbiah, Laura S. Angelo, Aung Naing, Peter M. Anderson, Cynthia E. Herzog, Siqing Fu, Robert S. Benjamin, Razelle Kurzrock

Published Jun 5, 2013 · Vol. 4, No. 6 · pp. 884-889

Keywords: Ewing sarcoma, PTPRD, mutation, germline

pRb controls Estrogen Receptor alpha protein stability and activity Research Paper

Isabella Caligiuri, Giuseppe Toffoli, Antonio Giordano, Flavio Rizzolio

Published Jun 3, 2013 · Vol. 4, No. 6 · pp. 875-883

Keywords: pRb, Estrogen receptor alpha, proteasome, chaperone proteins, breast cancer

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

Rabih Said, David S. Hong, Carla L. Warneke, J. Jack Lee, Jennifer J. Wheler, Filip Janku, Aung Naing, Gerald S. Falchook, Siqing Fu, Sarina Piha-Paul, Apostolia M. Tsimberidou, Razelle Kurzrock

Published May 1, 2013 · Vol. 4, No. 5 · pp. 705-714

Keywords: P53 mutations, PTEN loss, bevacizumab, Li-Fraumeni syndrome

Prostate derived Ets transcription factor and Carcinoembryonic antigen related cell adhesion molecule 6 constitute a highly active oncogenic axis in breast cancer Research Paper

Alka Mukhopadhyay, Thaer Khoury, Leighton Stein, Protul Shrikant, Ashwani K. Sood

Published Apr 10, 2013 · Vol. 4, No. 4 · pp. 610-621

Keywords: PDEF, SPDEF, CEACAM6, Elevated co-expression, Tumor cell survival, PDEF-CEACAM6 oncogenic axis, Novel targets in breast cancer

The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism Research Paper

Khoi Chu, Kimberkey M. Boley, Ricardo Moraes, Sanford H. Barsky, Fredika M. Robertson

Published Mar 21, 2013 · Vol. 4, No. 3 · pp. 446-462

Keywords: E-Cadherin, Inflammatory Breast Cander, Mesenchymal-Epithelial transition (MET), HIF-1Î±, Metabolism, Glycolysis

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) Research Paper

Kristen M. Reipas, Jennifer H. Law, Nicole Couto, Sumaiya Islam, Yvonne Li, Huifang Li, Artem Cherkasov, Karen Jung, Amarpal S. Cheema, Steven J.M. Jones, John A. Hassell, Sandra E. Dunn

Published Feb 27, 2013 · Vol. 4, No. 2 · pp. 329-345

Keywords: Triple-negative breast cancer, p90 ribosomal S6 kinase, Y-box binding protein-1, tumor-initiating cells, drug repositioning

TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells Research Paper

Dimitra Bourboulia, HuiYing Han, Sandra Jensen-Taubman, Noah Gavil, Biju Isaac, Beiyang Wei, Len Neckers, William Stetler-Stevenson

Published Jan 27, 2013 · Vol. 4, No. 1 · pp. 163-173

Keywords: TIMP-2, microarray analysis, E-cadherin, cell adhesion, tumor growth inhibition

Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer Research Paper

Sreedhar Venkannagari, Warren Fiskus, Karissa Peth, Peter Atadja, Manuel Hidalgo, Anirban Maitra, Kapil N Bhalla

Published Nov 15, 2012 · Vol. 3, No. 11 · pp. 1416-1427

Keywords: Pancreatic cancer, pan-HDAC inhibitor, BEZ235, mTOR, AKT

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

Andrew D Beggs, Enric Domingo, Megan McGregor, Mikael Presz, Elaine Johnstone, Rachel Midgley, David Kerr, Dahmane Oukrif, Marco Novelli, Muti Abulafi, Shirley V Hodgson, Wakkas Fadhil, Mohammed Ilyas, Ian P Tomlinson

Published Oct 28, 2012 · Vol. 3, No. 11 · pp. 1348-1355

Keywords: Double strand break repair, ATM, g-H2AX, colorectal cancer, prognosis

Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin Research Paper

Jantine Posthuma De Boer, Pim W. van Egmond, Marco N. Helder, RenÃ©e X. de Menezes, Anne-Marie Cleton-Jansen, Jeroen A.M. BeliÃ«n, Henk M.W. Verheul, Barend J. van Royen, Gert-Jan J.L. Kaspers, Victor W. van Beusechem

Published Sep 28, 2012 · Vol. 3, No. 10 · pp. 1169-1181

Keywords: osteosarcoma, functional genomics, siRNA, chemosensitisation, JIP1

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HOXA11 hypermethylation is associated with progression of non-small cell lung cancer Research Paper

ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX Research Paper

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine. Research Paper

Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice Research Paper

Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma Multiforme through de-repression of Bcl-xL translation Research Paper

PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1 Research Paper

Battle of the eternal rivals: restoring functional p53 and inhibiting Polo-like kinase 1 as cancer therapy Review

The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes. Research Paper

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

pRb controls Estrogen Receptor alpha protein stability and activity Research Paper

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

Prostate derived Ets transcription factor and Carcinoembryonic antigen related cell adhesion molecule 6 constitute a highly active oncogenic axis in breast cancer Research Paper

The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism Research Paper

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) Research Paper

TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells Research Paper

Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer Research Paper

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

HOXA11 hypermethylation is associated with progression of non-small cell lung cancer Research Paper

ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX Research Paper

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine. Research Paper

Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice Research Paper

Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma Multiforme through de-repression of Bcl-xL translation Research Paper

PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1 Research Paper

Battle of the eternal rivals: restoring functional p53 and inhibiting Polo-like kinase 1 as cancer therapy Review

The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes. Research Paper

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

pRb controls Estrogen Receptor alpha protein stability and activity Research Paper

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

Prostate derived Ets transcription factor and Carcinoembryonic antigen related cell adhesion molecule 6 constitute a highly active oncogenic axis in breast cancer Research Paper

The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism Research Paper

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) Research Paper

TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells Research Paper

Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer Research Paper

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin Research Paper