The Oncosearch | Oncotarget

Sorafenib and DE605, a novel c-Met inhibitor, synergistically suppress hepatocellular carcinoma Research Paper

Xiufeng Jiang, Kang Feng, Ye Zhang, Zengyao Li, Fan Zhou, Huiqiang Dou, Tong Wang

Published Mar 26, 2015 · Vol. 6, No. 14 · pp. 12340-12356

Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis Research Paper

SÃ©bastien TabariÃ¨s, Matthew G. Annis, Brian E. Hsu, Christine E. Tam, Paul Savage, Morag Park, Peter M. Siegel

Published Mar 25, 2015 · Vol. 6, No. 11 · pp. 9476-9487

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment Research Paper

Laura R. H. Ip, George Poulogiannis, Felipe Cia Viciano, Junko Sasaki, Satoshi Kofuji, Victoria J. Spanswick, Daniel Hochhauser, John A. Hartley, Takehiko Sasaki, Christina A. Gewinner

Published Mar 24, 2015 · Vol. 6, No. 12 · pp. 10548-10562

Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer Research Paper

Lyndsay V. Rhodes, Elizabeth C. Martin, H. Chris Segar, David F. B. Miller, Aaron Buechlein, Douglas B. Rusch, Kenneth P. Nephew, Matthew E. Burow, Bridgette M. Collins-Burow

Published Mar 21, 2015 · Vol. 6, No. 18 · pp. 16638-16652

High frequency of loss of PTEN expression in human solid salivary adenoid cystic carcinoma and its implication for targeted therapy Research Paper

Han Liu, Li Du, Ru Wang, Chao Wei, Bo Liu, Lei Zhu, Pixu Liu, Qiang Liu, Jiang Li, Shi-Long Lu, Jing Xiao

Published Mar 20, 2015 · Vol. 6, No. 13 · pp. 11477-11491

Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: novel HIF-1-mediated regulation of aquaporins in NP cells Research Paper

Zariel I. Johnson, Shilpa S. Gogate, Rebecca Day, Abbie Binch, Dessislava Z. Markova, Neil Chiverton, Ashley Cole, Matt Conner, Irving M. Shapiro, Christine L. Le Maitre, Makarand V. Risbud

Published Mar 20, 2015 · Vol. 6, No. 14 · pp. 11945-11958

Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy Research Paper

Wei An, Scott A. Nadeau, Bhopal C. Mohapatra, Dan Feng, Neha Zutshi, Matthew D. Storck, Priyanka Arya, James E. Talmadge, Jane L. Meza, Vimla Band, Hamid Band

Published Mar 19, 2015 · Vol. 6, No. 12 · pp. 10498-10509

Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance Research Paper

Fernando Gallardo, Andreina PadrÃ³n, Ricard Garcia-Carbonell, Cristina Rius, Abel GonzÃ¡lez-Perez, Montserrat ArumÃ-Uria, Mar Iglesias, Lara Nonell, Beatriz Bellosillo, Sonia Segura, Ramon Maria Pujol, Nuria Lopez-Bigas, Joan Bertran, Anna Bigas, LluÃs Espinosa

Published Mar 19, 2015 · Vol. 6, No. 11 · pp. 9284-9294

CD44 increases the efficiency of distant metastasis of breast cancer Research Paper

Suzanne McFarlane, Jonathan A. Coulter, Paul Tibbits, Anthony Oâ€™Grady, Cheryl McFarlane, Nicola Montgomery, Ashleigh Hill, Helen O. McCarthy, Leonie S. Young, Elaine W. Kay, Clare M. Isacke, David J.J. Waugh

Published Mar 19, 2015 · Vol. 6, No. 13 · pp. 11465-11476

A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis Research Paper

Liping Xiang, Ting Chi, Qiao Tang, Xiang Yang, Minrui Ou, Xiufen Chen, Xiaobo Yu, Jianzhong Chen, Rodney J.Y. Ho, Jingwei Shao, Lee Jia

Published Mar 19, 2015 · Vol. 6, No. 11 · pp. 9295-9312

Loss of β-catenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelial-to-mesenchymal transition Research Paper

Aude Salomon, Michelle Keramidas, CÃ©cile Maisin, MichaÃ«l Thomas

Published Mar 18, 2015 · Vol. 6, No. 13 · pp. 11421-11433

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer Research Paper

Yi-Nan Liu, Tzu-Hua Chang, Meng-Feng Tsai, Shang-Gin Wu, Tzu-Hsiu Tsai, Hsuan-Yu Chen, Sung-Liang Yu, James Chih-Hsin Yang, Jin-Yuan Shih

Published Mar 18, 2015 · Vol. 6, No. 12 · pp. 10415-10431

Prognostic value of receptor conversion after neoadjuvant chemotherapy in breast cancer patients: a prospective observational study Clinical Research Papers

Xi Jin, Yi-Zhou Jiang, Sheng Chen, Ke-Da Yu, Zhi-Ming Shao, Gen-Hong Di

Published Mar 16, 2015 · Vol. 6, No. 11 · pp. 9600-9611

Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice Research Paper

Thorsten Maass, Jens Marquardt, Ju-Seog Lee, Markus Krupp, Peter Scholz-Kreisel, Carolin Mogler, Peter Schirmacher, Martina MÃ¼ller, Heiner Westphal, Peter R. Galle, Andreas Teufel

Published Mar 16, 2015 · Vol. 7, No. 20 · pp. 28903-28913

PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors Research Paper

Annalisa Lonetti, Alessandra Cappellini, Antonino Maria SpartÃ, Francesca Chiarini, Francesca Buontempo, Camilla Evangelisti, Cecilia Evangelisti, Ester Orsini, James A. McCubrey, Alberto Maria Martelli

Published Mar 16, 2015 · Vol. 6, No. 12 · pp. 10399-10414

FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15 Research Paper

Ningning Li, Federica Lorenzi, Eliana Kalakouti, Makhliyo Normatova, Roya Babaei-Jadidi, Ian Tomlinson, Abdolrahman S. Nateri

Published Mar 16, 2015 · Vol. 6, No. 11 · pp. 9240-9256

Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3 Research Paper

Shicong Zhu, Zhihua Wang, Zijian Li, Hongling Peng, Yunya Luo, Mingyang Deng, Ruijuan Li, Chongwen Dai, Yunxiao Xu, Sufang Liu, Guangsen Zhang

Published Mar 16, 2015 · Vol. 6, No. 12 · pp. 10460-10472

Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy Research Paper

Frauke Nitzki, Ezequiel J. Tolosa, Nicole Cuvelier, Anke Frommhold, Gabriela Salinas-Riester, Steven A. Johnsen, Martin E. Fernandez-Zapico, Heidi Hahn

Published Mar 14, 2015 · Vol. 6, No. 11 · pp. 9113-9124

HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity Research Paper

Davide Valente, Gianluca Bossi, Alice Moncada, Mara Tornincasa, Stefania Indelicato, Salvatore Piscuoglio, Eva Diamantis Karamitopoulou, Armando Bartolazzi, Giovanna Maria Pierantoni, Alfredo Fusco, Silvia Soddu, Cinzia Rinaldo

Published Mar 14, 2015 · Vol. 6, No. 12 · pp. 10320-10334

PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins Research Paper

Valentina Zuco, Michelandrea De Cesare, Nadia Zaffaroni, Cinzia Lanzi, Giuliana Cassinelli

Published Mar 12, 2015 · Vol. 6, No. 11 · pp. 8736-8749

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Sorafenib and DE605, a novel c-Met inhibitor, synergistically suppress hepatocellular carcinoma Research Paper

Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis Research Paper

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment Research Paper

Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer Research Paper

High frequency of loss of PTEN expression in human solid salivary adenoid cystic carcinoma and its implication for targeted therapy Research Paper

Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: novel HIF-1-mediated regulation of aquaporins in NP cells Research Paper

Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy Research Paper

Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance Research Paper

CD44 increases the efficiency of distant metastasis of breast cancer Research Paper

A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis Research Paper

Loss of β-catenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelial-to-mesenchymal transition Research Paper

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer Research Paper

Prognostic value of receptor conversion after neoadjuvant chemotherapy in breast cancer patients: a prospective observational study Clinical Research Papers

Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice Research Paper

PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors Research Paper

FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15 Research Paper

Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3 Research Paper

Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy Research Paper

HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity Research Paper

PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Sorafenib and DE605, a novel c-Met inhibitor, synergistically suppress hepatocellular carcinoma Research Paper

Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis Research Paper

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment Research Paper

Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer Research Paper

High frequency of loss of PTEN expression in human solid salivary adenoid cystic carcinoma and its implication for targeted therapy Research Paper

Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: novel HIF-1-mediated regulation of aquaporins in NP cells Research Paper

Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy Research Paper

Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance Research Paper

CD44 increases the efficiency of distant metastasis of breast cancer Research Paper

A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis Research Paper

Loss of β-catenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelial-to-mesenchymal transition Research Paper

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer Research Paper

Prognostic value of receptor conversion after neoadjuvant chemotherapy in breast cancer patients: a prospective observational study Clinical Research Papers

Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice Research Paper

PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors Research Paper

FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15 Research Paper

Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3 Research Paper

Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy Research Paper

HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity Research Paper

PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins Research Paper