The Oncosearch | Oncotarget

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer Research Paper

Kyle C. Strickland, Brooke E. Howitt, Sachet A. Shukla, Scott Rodig, Lauren L. Ritterhouse, Joyce F. Liu, Judy E. Garber, Dipanjan Chowdhury, Catherine J. Wu, Alan D. Dâ€™Andrea, Ursula A. Matulonis, Panagiotis A. Konstantinopoulos

Published Feb 9, 2016 · Vol. 7, No. 12 · pp. 13587-13598

Rad18 is required for functional interactions between FANCD2, BRCA2, and Rad51 to repair DNA topoisomerase 1-poisons induced lesions and promote fork recovery Research Paper

Kaushlendra Tripathi, Chinnadurai Mani, David W Clark, Komaraiah Palle

Published Feb 8, 2016 · Vol. 7, No. 11 · pp. 12537-12553

Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer Research Paper

Po-Han Lin, Wen-Hung Kuo, Ai-Chu Huang, Yen-Shen Lu, Ching-Hung Lin, Sung-Hsin Kuo, Ming-Yang Wang, Chun-Yu Liu, Fiona Tsui-Fen Cheng, Ming-Hsin Yeh, Huei-Ying Li, Yu-Hsuan Yang, Yu-Hua Hsu, Sheng-Chih Fan, Long-Yuan Li, Sung-Liang Yu, King-Jen Chang, Pei-Lung Chen, Yen-Hsuan Ni, Chiun-Sheng Huang

Published Jan 27, 2016 · Vol. 7, No. 7 · pp. 8310-8320

PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response Research Paper

Stephanie Wurster, Fabian Hennes, Ann C. Parplys, Jasna I. Seelbach, Wael Y. Mansour, Alexandra Zielinski, Cordula Petersen, Till S. Clauditz, Adrian MÃ¼nscher, Anna A. Friedl, Kerstin Borgmann

Published Jan 19, 2016 · Vol. 7, No. 9 · pp. 9732-9741

Gene copy number variations in the leukocyte genome of hepatocellular carcinoma patients with integrated hepatitis B virus DNA Research Paper

Yanan Pang, Weixing Guo, Jiaqi Wang, Guixia Xu, Kai Cheng, Guangwen Cao, Mengchao Wu, Shuqun Cheng, Shanrong Liu

Published Jan 12, 2016 · Vol. 7, No. 7 · pp. 8006-8018

Polo-like kinase 1 mediates BRCA1 phosphorylation and recruitment at DNA double-strand breaks Research Paper

Corinne Chabalier-Taste, Laetitia Brichese, Carine Racca, Yvan Canitrot, Patrick Calsou, Florence Larminat

Published Jan 6, 2016 · Vol. 7, No. 3 · pp. 2269-2283

Double-strand break repair and colorectal cancer: gene variants within 3â€² UTRs and microRNAs binding as modulators of cancer risk and clinical outcome Research Paper

Alessio Naccarati, Fabio Rosa, Veronika Vymetalkova, Elisa Barone, Katerina Jiraskova, Cornelia Di Gaetano, Jan Novotny, Miroslav Levy, Ludmila Vodickova, Federica Gemignani, Tomas Buchler, Stefano Landi, Pavel Vodicka, Barbara Pardini

Published Dec 31, 2015 · Vol. 7, No. 17 · pp. 23156-23169

Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors Research Paper

Junhui Wang, Qianshan Ding, Hiroaki Fujimori, Akira Motegi, Yoshio Miki, Mitsuko Masutani

Published Dec 22, 2015 · Vol. 7, No. 7 · pp. 7701-7714

Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions Research Paper

Xiao-Man Liu, Yong-Ping Zhang, Shu-Yan Ji, Bo-Tai Li, Xuejun Tian, Dali Li, Chao Tong, Heng-Yu Fan

Published Dec 21, 2015 · Vol. 7, No. 2 · pp. 1155-1167

SATB1 and SATB2 play opposing roles in c-Myc expression and progression of colorectal cancer Research Paper

Mohammed A. Mansour, Toshinori Hyodo, Khondker Ayesha Akter, Toshio Kokuryo, Keisuke Uehara, Masato Nagino, Takeshi Senga

Published Dec 18, 2015 · Vol. 7, No. 4 · pp. 4993-5006

A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma Research Paper

Zhongqian Hu, Xinyi Wang, Haoshu Fang, Yakun Liu, Danlei Chen, Qian Zhang, Xia Liu, Daoyan Wei, Chengkui Qu, Siying Wang

Published Dec 10, 2015 · Vol. 7, No. 5 · pp. 5664-5676

Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer Research Paper

Ijeoma Umelo, Amir Noeparast, Gang Chen, Marleen Renard, Caroline Geers, Johan Vansteenkiste, Philippe Giron, Olivier De Wever, Erik Teugels, Jacques De GrÃ¨ve

Published Dec 9, 2015 · Vol. 7, No. 3 · pp. 3068-3083

Human Î²-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation Research Paper

Thanh Kha Phan, Fung T. Lay, Ivan K.H. Poon, Mark G. Hinds, Marc Kvansakul, Mark D. Hulett

Published Dec 9, 2015 · Vol. 7, No. 2 · pp. 2054-2069

SIRT1 inhibition impairs non-homologous end joining DNA damage repair by increasing Ku70 acetylation in chronic myeloid leukemia cells Research Paper

Wenjun Zhang, Haixia Wu, Meng Yang, Shiguang Ye, Liang Li, Hong Zhang, Jiong Hu, Xuguang Wang, Jun Xu, Aibin Liang

Published Dec 3, 2015 · Vol. 7, No. 12 · pp. 13538-13550

Upregulation of miR-181c contributes to chemoresistance in pancreatic cancer by inactivating the Hippo signaling pathway Research Paper

Meiyuan Chen, Min Wang, Simiao Xu, Xingjun Guo, Jianxin Jiang

Published Oct 26, 2015 · Vol. 6, No. 42 · pp. 44466-44479

Cancer metastasis and EGFR signaling is suppressed by amiodarone-induced versican V2 Research Paper

Hung-Chieh Lee, Mai-Yan Su, Hao-Chan Lo, Chin-Chieh Wu, Jia-Rung Hu, Dao-Ming Lo, Tsu-Yi Chao, Huai-Jen Tsai, Ming-Shen Dai

Published Oct 21, 2015 · Vol. 6, No. 40 · pp. 42976-42987

E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling Research Paper

Sharon McGonigle, Zhihong Chen, Jiayi Wu, Paul Chang, Donna Kolber-Simonds, Karen Ackermann, Natalie C. Twine, Jue-lon Shie, Jingzang Tao Miu, Kuan-Chun Huang, George A. Moniz, Kenichi Nomoto

Published Oct 20, 2015 · Vol. 6, No. 38 · pp. 41307-41323

Chromosome transplantation as a novel approach for correcting complex genomic disorders Priority Research Paper

Marianna Paulis, Alessandra Castelli, Lucia Susani, Michela Lizier, Irina Lagutina, Maria Luisa Focarelli, Camilla Recordati, Paolo Uva, Francesca Faggioli, Tui Neri, Eugenio Scanziani, Cesare Galli, Franco Lucchini, Anna Villa, Paolo Vezzoni

Published Oct 17, 2015 · Vol. 6, No. 34 · pp. 35218-35230

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition Priority Research Paper

Fiona K. Middleton, Miranda J. Patterson, Claire J. Elstob, Sarah Fordham, Ashleigh Herriott, Mark A. Wade, Aiste McCormick, Richard Edmondson, Felicity E.B. May, James M. Allan, John R. Pollard, Nicola J. Curtin

Published Oct 15, 2015 · Vol. 6, No. 32 · pp. 32396-32409

CGK733-induced LC3 II formation is positively associated with the expression of cyclin-dependent kinase inhibitor p21^Waf1/Cip1 through modulation of the AMPK and PERK/CHOP signaling pathways Research Paper

Yufeng Wang, Yasuhiro Kuramitsu, Byron Baron, Takao Kitagawa, Kazuhiro Tokuda, Junko Akada, Kazuyuki Nakamura

Published Oct 13, 2015 · Vol. 6, No. 37 · pp. 39692-39701

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Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer Research Paper

Rad18 is required for functional interactions between FANCD2, BRCA2, and Rad51 to repair DNA topoisomerase 1-poisons induced lesions and promote fork recovery Research Paper

Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer Research Paper

PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response Research Paper

Gene copy number variations in the leukocyte genome of hepatocellular carcinoma patients with integrated hepatitis B virus DNA Research Paper

Polo-like kinase 1 mediates BRCA1 phosphorylation and recruitment at DNA double-strand breaks Research Paper

Double-strand break repair and colorectal cancer: gene variants within 3â€² UTRs and microRNAs binding as modulators of cancer risk and clinical outcome Research Paper

Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors Research Paper

Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions Research Paper

SATB1 and SATB2 play opposing roles in c-Myc expression and progression of colorectal cancer Research Paper

A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma Research Paper

Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer Research Paper

Human Î²-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation Research Paper

SIRT1 inhibition impairs non-homologous end joining DNA damage repair by increasing Ku70 acetylation in chronic myeloid leukemia cells Research Paper

Upregulation of miR-181c contributes to chemoresistance in pancreatic cancer by inactivating the Hippo signaling pathway Research Paper

Cancer metastasis and EGFR signaling is suppressed by amiodarone-induced versican V2 Research Paper

E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling Research Paper

Chromosome transplantation as a novel approach for correcting complex genomic disorders Priority Research Paper

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition Priority Research Paper

CGK733-induced LC3 II formation is positively associated with the expression of cyclin-dependent kinase inhibitor p21^Waf1/Cip1 through modulation of the AMPK and PERK/CHOP signaling pathways Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer Research Paper

Rad18 is required for functional interactions between FANCD2, BRCA2, and Rad51 to repair DNA topoisomerase 1-poisons induced lesions and promote fork recovery Research Paper

Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer Research Paper

PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response Research Paper

Gene copy number variations in the leukocyte genome of hepatocellular carcinoma patients with integrated hepatitis B virus DNA Research Paper

Polo-like kinase 1 mediates BRCA1 phosphorylation and recruitment at DNA double-strand breaks Research Paper

Double-strand break repair and colorectal cancer: gene variants within 3â€² UTRs and microRNAs binding as modulators of cancer risk and clinical outcome Research Paper

Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors Research Paper

Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions Research Paper

SATB1 and SATB2 play opposing roles in c-Myc expression and progression of colorectal cancer Research Paper

A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma Research Paper

Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer Research Paper

Human Î²-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation Research Paper

SIRT1 inhibition impairs non-homologous end joining DNA damage repair by increasing Ku70 acetylation in chronic myeloid leukemia cells Research Paper

Upregulation of miR-181c contributes to chemoresistance in pancreatic cancer by inactivating the Hippo signaling pathway Research Paper

Cancer metastasis and EGFR signaling is suppressed by amiodarone-induced versican V2 Research Paper

E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling Research Paper

Chromosome transplantation as a novel approach for correcting complex genomic disorders Priority Research Paper

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition Priority Research Paper

CGK733-induced LC3 II formation is positively associated with the expression of cyclin-dependent kinase inhibitor p21Waf1/Cip1 through modulation of the AMPK and PERK/CHOP signaling pathways Research Paper

CGK733-induced LC3 II formation is positively associated with the expression of cyclin-dependent kinase inhibitor p21^Waf1/Cip1 through modulation of the AMPK and PERK/CHOP signaling pathways Research Paper