The Oncosearch | Oncotarget

A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization Research Paper

Min He, Xin Hu, Li Chen, A-Yong Cao, Ke-Da Yu, Ting-Yan Shi, Xia-Ying Kuang, Wen-Biao Shi, Hong Ling, Shan Li, Feng Qiao, Ling Yao, Qingyi Wei, Gen-Hong Di, Zhi-Ming Shao

Published Oct 22, 2014 · Vol. 5, No. 23 · pp. 12218-12232

Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide Research Paper

Kit Man Chai, Chih-Yen Wang, Hung-Jiun Liaw, Kuan-Min Fang, Chung-Shi Yang, Shun-Fen Tzeng

Published Oct 7, 2014 · Vol. 5, No. 21 · pp. 10901-10915

Keywords: BRCC3, BRCC36, ï§H2AX, DNA repair, Glioblastoma

TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1 Research Paper

Soo-Im Choi, Seo-Yeon Kim, Jaeha Lee, Eun-Wie Cho, In-Gyu Kim

Published Sep 8, 2014 · Vol. 5, No. 20 · pp. 9823-9837

Chronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma Research Paper

Wen-Pin Su, Sen-Huei Hsu, Cheng-Kuei Wu, Song-Bin Chang, Yi-Ju Lin, Wen-Bin Yang, Jan-Jong Hung, Wen-Tai Chiu, Shun-Fen Tzeng, Yau-Lin Tseng, Jang-Yang Chang, Wu-Chou Su, Hungjiun Liaw

Published Jul 12, 2014 · Vol. 5, No. 15 · pp. 6323-6337

FAS/FASL are dysregulated in chordoma and their loss-of-function impairs zebrafish notochord formation Research Paper

Luca Ferrari, Anna Pistocchi, Laura Libera, Nicola Boari, Pietro Mortini, Gianfranco Bellipanni, Antonio Giordano, Franco Cotelli, Paola Riva

Published Jul 1, 2014 · Vol. 5, No. 14 · pp. 5712-5724

Histone deacetylase inhibitor treatment induces â€˜BRCAnessâ€™ and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells Research Paper

Kyungsoo Ha, Warren Fiskus, Dong Soon Choi, Srividya Bhaskara, Leandro Cerchietti, Santhana G. T. Devaraj, Bhavin Shah, Sunil Sharma, Jenny C. Chang, Ari M. Melnick, Scott Hiebert, Kapil N. Bhalla

Published Jun 30, 2014 · Vol. 5, No. 14 · pp. 5637-5650

Antitumor activity of S116836, a novel tyrosine kinase inhibitor, against imatinib-resistant FIP1L1-PDGFRÎ±-expressing cells Research Paper

Yingying Shen, Xiaomei Ren, Ke Ding, Zhang Zhang, Deping Wang, Jingxuan Pan

Published Jun 11, 2014 · Vol. 5, No. 21 · pp. 10407-10420

Expression and functionality of histone H2A variants in cancer Review

FÃ¡tima Liliana Monteiro, Tiago Baptista, Francisco Amado, Rui Vitorino, Carmen JerÃ³nimo, Luisa A. Helguero

Published May 26, 2014 · Vol. 5, No. 11 · pp. 3428-3443

Sublethal concentrations of 17-AAG suppress homologous recombination DNA repair and enhance sensitivity to carboplatin and olaparib in HR proficient ovarian cancer cells Research Paper

Young Eun Choi, Chiara Battelli, Jacqueline Watson, Joyce Liu, Jennifer Curtis, Alexander N. Morse, Ursula A. Matulonis, Dipanjan Chowdhury, Panagiotis A. Konstantinopoulos

Published Apr 30, 2014 · Vol. 5, No. 9 · pp. 2678-2687

RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation Research Paper

Ming Yuan, Charles G. Eberhart, Mihoko Kai

Published Apr 27, 2014 · Vol. 5, No. 9 · pp. 2820-2826

The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma Research Paper

Ken Maes, Eva De Smedt, Miguel Lemaire, Hendrik De Raeve, Eline Menu, Els Van Valckenborgh, Steve McClue, Karin Vanderkerken, Elke De Bruyne

Published Mar 22, 2014 · Vol. 5, No. 10 · pp. 3115-3129

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

Yan Cao, Yan Xu, Lei Zhang, Zhen Li, Ying Jiang, Xiao Tian, Andrei Seluanov, Vera Gorbunova, Zhiyong Mao

Published Feb 19, 2014 · Vol. 5, No. 7 · pp. 1805-1811

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

Changcun Guo, Lee H. Chen, Yafen Huang, Chun-Chi Chang, Ping Wang, Christopher J. Pirozzi, Xiaoxia Qin, Xuhui Bao, Paula K. Greer, Roger E. McLendon, Hai Yan, Stephen T. Keir, Darell D. Bigner, Yiping He

Published Nov 3, 2013 · Vol. 4, No. 11 · pp. 2144-2153

Keywords: MLL2, isogenic cell line, gene knockout, enhancer

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX Research Paper

Marissa V Powers, Melanie Valenti, Susana Mirander, Alison Maloney, Suzanne A Eccles, George Thomas, Paul A Clarke, Paul Workman

Published Sep 29, 2013 · Vol. 4, No. 11 · pp. 1963-1975

Keywords: 17-AAG, HSP90, BAX, Apoptosis, Colon cancer

Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma Research Paper

Ryan T Pitman, Luke Wojdyla, Neelu Puri

Published Jun 3, 2013 · Vol. 4, No. 5 · pp. 761-771

Keywords: T-oligo, Tankyrase, TRF1, telomere, p53, melanoma

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

Andrew D Beggs, Enric Domingo, Megan McGregor, Mikael Presz, Elaine Johnstone, Rachel Midgley, David Kerr, Dahmane Oukrif, Marco Novelli, Muti Abulafi, Shirley V Hodgson, Wakkas Fadhil, Mohammed Ilyas, Ian P Tomlinson

Published Oct 28, 2012 · Vol. 3, No. 11 · pp. 1348-1355

Keywords: Double strand break repair, ATM, g-H2AX, colorectal cancer, prognosis

AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers Review

Published Dec 16, 2010 · Vol. 1, No. 8 · pp. 691-699

Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks Research Paper

Rachael Elizabeth Hawtin, David Elliot Stockett, Oi Kwan Wong, Cecilia Lundin, Thomas Helleday, Judith Ann Fox

Published Nov 22, 2010 · Vol. 1, No. 7 · pp. 606-619

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A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization Research Paper

Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide Research Paper

TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1 Research Paper

Chronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma Research Paper

FAS/FASL are dysregulated in chordoma and their loss-of-function impairs zebrafish notochord formation Research Paper

Histone deacetylase inhibitor treatment induces â€˜BRCAnessâ€™ and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells Research Paper

Antitumor activity of S116836, a novel tyrosine kinase inhibitor, against imatinib-resistant FIP1L1-PDGFRÎ±-expressing cells Research Paper

Expression and functionality of histone H2A variants in cancer Review

Sublethal concentrations of 17-AAG suppress homologous recombination DNA repair and enhance sensitivity to carboplatin and olaparib in HR proficient ovarian cancer cells Research Paper

RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation Research Paper

The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma Research Paper

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX Research Paper

Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma Research Paper

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers Review

Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization Research Paper

Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide Research Paper

TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1 Research Paper

Chronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma Research Paper

FAS/FASL are dysregulated in chordoma and their loss-of-function impairs zebrafish notochord formation Research Paper

Histone deacetylase inhibitor treatment induces â€˜BRCAnessâ€™ and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells Research Paper

Antitumor activity of S116836, a novel tyrosine kinase inhibitor, against imatinib-resistant FIP1L1-PDGFRÎ±-expressing cells Research Paper

Expression and functionality of histone H2A variants in cancer Review

Sublethal concentrations of 17-AAG suppress homologous recombination DNA repair and enhance sensitivity to carboplatin and olaparib in HR proficient ovarian cancer cells Research Paper

RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation Research Paper

The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma Research Paper

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX Research Paper

Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma Research Paper

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN Research Paper

AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers Review

Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks Research Paper