The Oncosearch | Oncotarget

Î²2-spectrin depletion impairs DNA damage repair Priority Research Paper

Nobuo Horikoshi, Raj K. Pandita, Kalpana Mujoo, Shashank Hambarde, Dharmendra Sharma, Abid R. Mattoo, Sharmistha Chakraborty, Vijaya Charaka, Clayton R. Hunt, Tej K. Pandita

Published May 27, 2016 · Vol. 7, No. 23 · pp. 33557-33570

Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer Research Paper

Mahmoud Toulany, Mari Iida, Simone Keinath, Firdevs F. Iyi, Katharina Mueck, Birgit Fehrenbacher, Wael Y. Mansour, Martin Schaller, Deric L. Wheeler, H. Peter Rodemann

Published May 27, 2016 · Vol. 7, No. 28 · pp. 43746-43761

Paclitaxel is necessary for improved survival in epithelial ovarian cancers with homologous recombination gene mutations Clinical Research Papers

Stephanie Jean, Jiaqi Li, Dionyssios Katsaros, Bradley Wubbenhorst, Kara N. Maxwell, Lauren Fishbein, Michael W. McLane, Chiara Benedetto, Emilie Marion Canuto, Nandita Mitra, Lin Zhang, Katherine L. Nathanson, Janos L. Tanyi

Published May 14, 2016 · Vol. 7, No. 30 · pp. 48577-48585

Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress Research Paper

Yao Zhang, Jinzhi Lai, Zhanwen Du, Jinnan Gao, Shuming Yang, Shashank Gorityala, Xiahui Xiong, Ou Deng, Zhefu Ma, Chunhong Yan, Gonzalo Susana, Yan Xu, Junran Zhang

Published May 4, 2016 · Vol. 7, No. 23 · pp. 34688-34702

Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair Research Paper

Julio CastaÃ±o, Ana B. Herrero, Aldeheid Bursen, Federico GonzÃ¡lez, Rolf Marschalek, Norma C. GutiÃ©rrez, Pablo Menendez

Published Apr 22, 2016 · Vol. 7, No. 21 · pp. 30440-30452

Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway Research Paper

Kyung Hye Baek, Han Vit Yu, Eosu Kim, Younghwa Na, Youngjoo Kwon

Published Apr 18, 2016 · Vol. 7, No. 21 · pp. 30831-30844

The DNA resection protein CtIP promotes mammary tumorigenesis Research Paper

Colleen R. Reczek, Reena Shakya, Yana Miteva, Matthias Szabolcs, Thomas Ludwig, Richard Baer

Published Apr 6, 2016 · Vol. 7, No. 22 · pp. 32172-32183

Gene silencing of indoleamine 2,3-dioxygenase 2 in melanoma cells induces apoptosis through the suppression of NAD+ and inhibits in vivo tumor growth Research Paper

Yanling Liu, Yujuan Zhang, Xiufen Zheng, Xusheng Zhang, Hongmei Wang, Qin Li, Keng Yuan, Nanjing Zhou, Yanrong Yu, Na Song, Jiamin Fu, Weiping Min

Published Apr 6, 2016 · Vol. 7, No. 22 · pp. 32329-32340

Downregulation of LncRNA GAS5 causes trastuzumab resistance in breast cancer Research Paper

Wentong Li, Limin Zhai, Hui Wang, Chuanliang Liu, Jinbao Zhang, Weijuan Chen, Qun Wei

Published Mar 28, 2016 · Vol. 7, No. 19 · pp. 27778-27786

Dual inhibition of ATR and ATM potentiates the activity of trabectedin and lurbinectedin by perturbing the DNA damage response and homologous recombination repair Research Paper

Michelle Lima, Hana Bouzid, Daniele G. Soares, FrÃ©dÃ©ric Selle, Claire Morel, Carlos M. Galmarini, JoÃ£o A. P. Henriques, Annette K. Larsen, Alexandre E. Escargueil

Published Mar 23, 2016 · Vol. 7, No. 18 · pp. 25885-25901

Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations Research Paper

Vyom Sharma, Leonard B. Collins, Ting-huei Chen, Natalie Herr, Shunichi Takeda, Wei Sun, James A Swenberg, Jun Nakamura

Published Mar 23, 2016 · Vol. 7, No. 18 · pp. 25377-25390

Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress Research Paper

Yafei Dai, Lujuan Wang, Jingqun Tang, Pengfei Cao, Zhaohui Luo, Jun Sun, Abraha Kiflu, Buqing Sai, Meili Zhang, Fan Wang, Guiyuan Li, Juanjuan Xiang

Published Mar 18, 2016 · Vol. 7, No. 18 · pp. 25478-25492

Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells Research Paper

Roberta Montalbano, Birgit Honrath, Thaddeus Till Wissniowski, Moritz Elxnat, Silvia Roth, Matthias Ocker, Karl Quint, Yuri Churin, Martin Roederfeld, Dirk Schroeder, Dieter Glebe, Elke Roeb, Pietro Di Fazio

Published Mar 7, 2016 · Vol. 7, No. 15 · pp. 20312-20323

Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2 Research Paper

Mateusz Rytelewski, Saman Maleki Vareki, Lingegowda S. Mangala, Larissa Romanow, Dahai Jiang, Sunila Pradeep, Christian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Rene Figueredo, Peter J. Ferguson, Mark Vincent, Anil K. Sood, James D. Koropatnick

Published Mar 3, 2016 · Vol. 7, No. 15 · pp. 20825-20839

C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease Research Paper

Shing-Hwa Liu, Cheng-Tien Wu, Kuo-How Huang, Ching-Chia Wang, Siao-Syun Guan, Li-Ping Chen, Chih-Kang Chiang

Published Mar 3, 2016 · Vol. 7, No. 16 · pp. 21900-21912

Chemical chaperon 4-phenylbutyrate protects against the endoplasmic reticulum stress-mediated renal fibrosis in vivo and in vitro Research Paper

Shing-Hwa Liu, Ching-Chin Yang, Ding-Cheng Chan, Cheng-Tien Wu, Li-Ping Chen, Jenq-Wen Huang, Kuan-Yu Hung, Chih-Kang Chiang

Published Mar 3, 2016 · Vol. 7, No. 16 · pp. 22116-22127

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells Research Paper

Dario Palmieri, Mario Scarpa, Anna Tessari, Rexhep Uka, Foued Amari, Cindy Lee, Timothy Richmond, Claudia Foray, Tyler Sheetz, Ashley Braddom, Christin E. Burd, Jeffrey D. Parvin, Thomas Ludwig, Carlo M. Croce, Vincenzo Coppola

Published Mar 1, 2016 · Vol. 7, No. 14 · pp. 18371-18383

SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway Research Paper

Yiming Tao, Kuan Hu, Fengbo Tan, Sai Zhang, Ming Zhou, Jia Luo, Zhiming Wang

Published Feb 28, 2016 · Vol. 7, No. 14 · pp. 18356-18370

An EBV recombinant deleted for residues 130-159 in EBNA3C can deregulate p53/Mdm2 and Cyclin D1/CDK6 which results in apoptosis and reduced cell proliferation Research Paper

Sanket Kumar Shukla, Hem Chandra Jha, Darine W. El-Naccache, Erle S. Robertson

Published Feb 19, 2016 · Vol. 7, No. 14 · pp. 18116-18134

Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair Research Paper

Michael P. Croglio, Jefferson M. Haake, Colin P. Ryan, Victor S. Wang, Jennifer Lapier, Jamie P. Schlarbaum, Yaron Dayani, Emma Artuso, Cristina Prandi, Hinanit Koltai, Keli Agama, Yves Pommier, Yu Chen, Lucas Tricoli, Jeannine R. LaRocque, Christopher Albanese, Ronit I. Yarden

Published Feb 16, 2016 · Vol. 7, No. 12 · pp. 13984-14001

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Î²2-spectrin depletion impairs DNA damage repair Priority Research Paper

Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer Research Paper

Paclitaxel is necessary for improved survival in epithelial ovarian cancers with homologous recombination gene mutations Clinical Research Papers

Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress Research Paper

Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair Research Paper

Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway Research Paper

The DNA resection protein CtIP promotes mammary tumorigenesis Research Paper

Gene silencing of indoleamine 2,3-dioxygenase 2 in melanoma cells induces apoptosis through the suppression of NAD+ and inhibits in vivo tumor growth Research Paper

Downregulation of LncRNA GAS5 causes trastuzumab resistance in breast cancer Research Paper

Dual inhibition of ATR and ATM potentiates the activity of trabectedin and lurbinectedin by perturbing the DNA damage response and homologous recombination repair Research Paper

Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations Research Paper

Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress Research Paper

Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells Research Paper

Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2 Research Paper

C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease Research Paper

Chemical chaperon 4-phenylbutyrate protects against the endoplasmic reticulum stress-mediated renal fibrosis in vivo and in vitro Research Paper

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells Research Paper

SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway Research Paper

An EBV recombinant deleted for residues 130-159 in EBNA3C can deregulate p53/Mdm2 and Cyclin D1/CDK6 which results in apoptosis and reduced cell proliferation Research Paper

Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Î²2-spectrin depletion impairs DNA damage repair Priority Research Paper

Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer Research Paper

Paclitaxel is necessary for improved survival in epithelial ovarian cancers with homologous recombination gene mutations Clinical Research Papers

Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress Research Paper

Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair Research Paper

Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway Research Paper

The DNA resection protein CtIP promotes mammary tumorigenesis Research Paper

Gene silencing of indoleamine 2,3-dioxygenase 2 in melanoma cells induces apoptosis through the suppression of NAD+ and inhibits in vivo tumor growth Research Paper

Downregulation of LncRNA GAS5 causes trastuzumab resistance in breast cancer Research Paper

Dual inhibition of ATR and ATM potentiates the activity of trabectedin and lurbinectedin by perturbing the DNA damage response and homologous recombination repair Research Paper

Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations Research Paper

Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress Research Paper

Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells Research Paper

Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2 Research Paper

C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease Research Paper

Chemical chaperon 4-phenylbutyrate protects against the endoplasmic reticulum stress-mediated renal fibrosis in vivo and in vitro Research Paper

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells Research Paper

SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway Research Paper

An EBV recombinant deleted for residues 130-159 in EBNA3C can deregulate p53/Mdm2 and Cyclin D1/CDK6 which results in apoptosis and reduced cell proliferation Research Paper

Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair Research Paper