The Oncosearch | Oncotarget

Effectiveness and safety of poly (ADP-ribose) polymerase inhibitors in cancer therapy: A systematic review and meta-analysis Clinical Review

Zhengqiang Bao, Chao Cao, Xinwei Geng, Baoping Tian, Yanping Wu, Chao Zhang, Zhihua Chen, Wen Li, Huahao Shen, Songmin Ying

Published Sep 22, 2015 · Vol. 7, No. 7 · pp. 7629-7639

Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response Research Paper

Meichun Xing, Xiaohui Wang, Timea Palmai-Pallag, Huahao Shen, Thomas Helleday, Ian D. Hickson, Songmin Ying

Published Sep 22, 2015 · Vol. 6, No. 35 · pp. 37638-37646

HER2 as a novel therapeutic target for cervical cancer Research Paper

Doo-Yi Oh, Seokhwi Kim, Yoon-La Choi, Young Jae Cho, Ensel Oh, Jung-Joo Choi, Kyungsoo Jung, Ji-Young Song, Suzie E. Ahn, Byoung-Gie Kim, Duk-Soo Bae, Woong-Yang Park, Jeong-Won Lee, Sangyong Song

Published Sep 21, 2015 · Vol. 6, No. 34 · pp. 36219-36230

Evaluation of a novel human IgG1 anti-claudin3 antibody that specifically recognizes its aberrantly localized antigen in ovarian cancer cells and that is suitable for selective drug delivery Research Paper

Chiara Romani, Emiliano Cocco, Eliana Bignotti, Daniele Moratto, Antonella Bugatti, Paola Todeschini, Elisabetta Bandiera, Renata Tassi, Laura Zanotti, Sergio Pecorelli, Enrico Sartori, Franco E. Odicino, Ario de Marco, Alessandro Davide Santin, Antonella Ravaggi, Stefania Mitola

Published Sep 21, 2015 · Vol. 6, No. 33 · pp. 34617-34628

Heat shock factor 1, an inhibitor of non-homologous end joining repair Research Paper

Ga-Young Kang, Eun-Ho Kim, Hae-June Lee, Na-Yeon Gil, Hyuk-Jin Cha, Yun-Sil Lee

Published Aug 24, 2015 · Vol. 6, No. 30 · pp. 29712-29724

DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma Research Paper

Alice N. Weaver, Tiffiny S. Cooper, Marcela Rodriguez, Hoa Q. Trummell, James A. Bonner, Eben L. Rosenthal, Eddy S. Yang

Published Aug 22, 2015 · Vol. 6, No. 29 · pp. 26995-27007

Dissecting the contribution of EBNA3C domains important for EBV-induced B-cell growth and proliferation Research Paper

Hem Chandra Jha, Sanket Kumar Shukla, Jie Lu, Mahadesh Prasad Aj, Shuvomoy Banerjee, Erle S. Robertson

Published Aug 18, 2015 · Vol. 6, No. 30 · pp. 30115-30129

Activation of homologous recombination DNA repair in human skin fibroblasts continuously exposed to X-ray radiation Research Paper

Andreyan N. Osipov, Anna Grekhova, Margarita Pustovalova, Ivan V. Ozerov, Petr Eremin, Natalia Vorobyeva, Natalia Lazareva, Andrey Pulin, Alex Zhavoronkov, Sergey Roumiantsev, Dmitry Klokov, Ilya Eremin

Published Aug 13, 2015 · Vol. 6, No. 29 · pp. 26876-26885

Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining Research Paper

Jason M. Beckta, Seth M. Dever, Nisha Gnawali, Ashraf Khalil, Amrita Sule, Sarah E. Golding, Elizabeth Rosenberg, Aarthi Narayanan, Kylene Kehn-Hall, Bo Xu, Lawrence F. Povirk, Kristoffer Valerie

Published Aug 12, 2015 · Vol. 6, No. 29 · pp. 27674-27687

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure Research Paper

Yves-Paul Vandewynckel, Debby Laukens, Lindsey Devisscher, Annelies Paridaens, Eliene Bogaerts, Xavier Verhelst, Anja Van den Bussche, Sarah Raevens, Christophe Van Steenkiste, Marleen Van Troys, Christophe Ampe, Benedicte Descamps, Chris Vanhove, Olivier Govaere, Anja Geerts, Hans Van Vlierberghe

Published Jul 20, 2015 · Vol. 6, No. 29 · pp. 28011-28025

Keywords: hepatocellular carcinoma, unfolded protein response, inflammation, chemoprevention, chaperone

Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms Research Paper

Ching-Ying Kuo, Wen-Cheng Chou, Chin-Chung Wu, Teng-Song Wong, Rajesh Kakadiya, Te-Chang Lee, Tsann-Long Su, Hui-Chun Wang

Published Jul 17, 2015 · Vol. 6, No. 28 · pp. 25770-25783

PERK/CHOP contributes to the CGK733-induced vesicular calcium sequestration which is accompanied by non-apoptotic cell death Research Paper

Yufeng Wang, Yasuhiro Kuramitsu, Byron Baron, Takao Kitagawa, Junko Akada, Kazuhiro Tokuda, Dan Cui, Kazuyuki Nakamura

Published Jul 10, 2015 · Vol. 6, No. 28 · pp. 25252-25265

High RAD54B expression: an independent predictor of postoperative distant recurrence in colorectal cancer patients Research Paper

Yuzo Nagai, Yoko Yamamoto, Takaaki Yasuhara, Keisuke Hata, Takeshi Nishikawa, Toshiaki Tanaka, Junichiro Tanaka, Tomomichi Kiyomatsu, Kazushige Kawai, Hiroaki Nozawa, Shinsuke Kazama, Hironori Yamaguchi, Soichiro Ishihara, Eiji Sunami, Takeharu Yamanaka, Kiyoshi Miyagawa, Toshiaki Watanabe

Published May 20, 2015 · Vol. 6, No. 25 · pp. 21064-21073

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition Priority Research Paper

Ying Shen, Jie Li, Masayuki Nitta, Diahnn Futalan, Tyler Steed, Jeffrey M. Treiber, Zack Taich, Deanna Stevens, Jill Wykosky, Hong-Zhuan Chen, Bob S. Carter, Oren J. Becher, Richard Kennedy, Fumiko Esashi, Jann N. Sarkaria, Frank B. Furnari, Webster K. Cavenee, Arshad Desai, Clark C. Chen

Published May 5, 2015 · Vol. 6, No. 14 · pp. 11751-11767

ATRX represses alternative lengthening of telomeres Research Paper

Christine E. Napier, Lily I. Huschtscha, Adam Harvey, Kylie Bower, Jane R. Noble, Eric A. Hendrickson, Roger R. Reddel

Published Apr 15, 2015 · Vol. 6, No. 18 · pp. 16543-16558

5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair Research Paper

Upadhyayula Sai Srinivas, Jerzy Dyczkowski, Tim BeiÃŸbarth, Jochen Gaedcke, Wael Y. Mansour, Kerstin Borgmann, Matthias Dobbelstein

Published Mar 30, 2015 · Vol. 6, No. 14 · pp. 12574-12586

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity Priority Research Paper

Jessica Frankum, Pavel Moudry, Rachel Brough, Zdenek Hodny, Alan Ashworth, Jiri Bartek, Christopher J. Lord

Published Mar 18, 2015 · Vol. 6, No. 13 · pp. 10746-10758

Carnosic acid sensitized TRAIL-mediated apoptosis through down-regulation of c-FLIP and Bcl-2 expression at the post translational levels and CHOP-dependent up-regulation of DR5, Bim, and PUMA expression in human carcinoma caki cells Research Paper

Kyong-Jin Jung, Kyoung-Jin Min, Jae Hoon Bae, Taeg Kyu Kwon

Published Jan 22, 2015 · Vol. 6, No. 3 · pp. 1556-1568

Keywords: Carnosic acid, TRAIL, Bcl-2, c-FLIP, CHOP

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

Jara Majuelos-Melguizo, MarÃa Isabel RodrÃguez, Laura LÃ³pez-JimÃ©nez, Jose M. RodrÃguez-Vargas, Juan M. MartÃ MartÃn-Consuegra, Santiago Serrano-SÃ¡enz, Julie Gavard, J. Mariano Ruiz de AlmodÃ³var, F. Javier Oliver

Published Dec 11, 2014 · Vol. 6, No. 7 · pp. 4790-4803

Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process Research Paper

Nicola Alessio, Stefania Del Gaudio, Stefania Capasso, Giovanni Di Bernardo, Salvatore Cappabianca, Marilena Cipollaro, Gianfranco Peluso, Umberto Galderisi

Published Dec 11, 2014 · Vol. 6, No. 10 · pp. 8155-8166

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Effectiveness and safety of poly (ADP-ribose) polymerase inhibitors in cancer therapy: A systematic review and meta-analysis Clinical Review

Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response Research Paper

HER2 as a novel therapeutic target for cervical cancer Research Paper

Evaluation of a novel human IgG1 anti-claudin3 antibody that specifically recognizes its aberrantly localized antigen in ovarian cancer cells and that is suitable for selective drug delivery Research Paper

Heat shock factor 1, an inhibitor of non-homologous end joining repair Research Paper

DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma Research Paper

Dissecting the contribution of EBNA3C domains important for EBV-induced B-cell growth and proliferation Research Paper

Activation of homologous recombination DNA repair in human skin fibroblasts continuously exposed to X-ray radiation Research Paper

Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining Research Paper

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure Research Paper

Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms Research Paper

PERK/CHOP contributes to the CGK733-induced vesicular calcium sequestration which is accompanied by non-apoptotic cell death Research Paper

High RAD54B expression: an independent predictor of postoperative distant recurrence in colorectal cancer patients Research Paper

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition Priority Research Paper

ATRX represses alternative lengthening of telomeres Research Paper

5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair Research Paper

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity Priority Research Paper

Carnosic acid sensitized TRAIL-mediated apoptosis through down-regulation of c-FLIP and Bcl-2 expression at the post translational levels and CHOP-dependent up-regulation of DR5, Bim, and PUMA expression in human carcinoma caki cells Research Paper

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Effectiveness and safety of poly (ADP-ribose) polymerase inhibitors in cancer therapy: A systematic review and meta-analysis Clinical Review

Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response Research Paper

HER2 as a novel therapeutic target for cervical cancer Research Paper

Evaluation of a novel human IgG1 anti-claudin3 antibody that specifically recognizes its aberrantly localized antigen in ovarian cancer cells and that is suitable for selective drug delivery Research Paper

Heat shock factor 1, an inhibitor of non-homologous end joining repair Research Paper

DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma Research Paper

Dissecting the contribution of EBNA3C domains important for EBV-induced B-cell growth and proliferation Research Paper

Activation of homologous recombination DNA repair in human skin fibroblasts continuously exposed to X-ray radiation Research Paper

Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining Research Paper

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure Research Paper

Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms Research Paper

PERK/CHOP contributes to the CGK733-induced vesicular calcium sequestration which is accompanied by non-apoptotic cell death Research Paper

High RAD54B expression: an independent predictor of postoperative distant recurrence in colorectal cancer patients Research Paper

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition Priority Research Paper

ATRX represses alternative lengthening of telomeres Research Paper

5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair Research Paper

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity Priority Research Paper

Carnosic acid sensitized TRAIL-mediated apoptosis through down-regulation of c-FLIP and Bcl-2 expression at the post translational levels and CHOP-dependent up-regulation of DR5, Bim, and PUMA expression in human carcinoma caki cells Research Paper

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process Research Paper