The Oncosearch | Oncotarget

Mouse models and anti-HER2 therapies News and Commentaries

Ariella B. Hanker, Rebecca S. Cook, Carlos L. Arteaga

Published Nov 15, 2013 · Vol. 4, No. 11 · pp. 1866-1867

Keywords: HER2, PI3K, breast cancer, mouse model

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Research Paper

Shahin Assefnia, Sivanesan Dakshanamurthy, Jaime M. Guidry Auvil, Constanze Hampel, Panos Z. Anastasiadis, Bhaskar Kallakury, Aykut Uren, David W. Foley, Milton L. Brown, Lawrence Shapiro, Michael Brenner, David Haigh, Stephen W. Byers

Published Nov 15, 2013 · Vol. 5, No. 6 · pp. 1458-1474

Keywords: cadherin-11, breast cancer, glioblastoma, small molecule inhibitor, rheumatoid arthritis, celecoxib

Chemokines in tumor progression and metastasis Review

Purvaba J. Sarvaiya, Donna Guo, Ilya V. Ulasov, Patrik Gabikian, Maciej S. Lesniak

Published Nov 9, 2013 · Vol. 4, No. 12 · pp. 2171-2185

Keywords: Chemokines, chemokine receptors, cancer, metastasis

SCF^Î²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper

Jiateng Zhong, Shavali Shaik, Lixin Wan, Adriana E. Tron, Zhiwei Wang, Liankun Sun, Hiroyuki Inuzuka, Wenyi Wei

Published Nov 6, 2013 · Vol. 4, No. 12 · pp. 2339-2353

Keywords: tumor suppressor, MTSS1, ubiquitination, phosphorylation, migration

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

Kaiming Xu, Lanfang Wang, Hui-Kuo G. Shu

Published Oct 31, 2013 · Vol. 5, No. 5 · pp. 1241-1252

Keywords: glioblastoma, brain tumor, tumorigenesis, cyclooxygenase-2, Id1

Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms Research Paper

Mackenzie Herroon, Erandi Rajagurubandara, Aimalie L Hardaway, Katelyn Powell, Audrey Turchick, Daniel Feldmann, Izabela Podgorski

Published Oct 29, 2013 · Vol. 4, No. 11 · pp. 2108-2123

Keywords: bone marrow adipocytes, bone metastasis, prostate cancer, breast cancer, interleukin 1ÃŸ, heme oxygenase 1

Adipose-derived mesenchymal stem cells (ASCs) may favour breast cancer recurrence via HGF/c-Met signaling. Research Paper

Vincenzo Eterno, Alberto Zambelli, Lorenzo Pavesi, Laura Villani, Vittorio Zanini, Gianfranco Petrolo, Stefania Manera, Antonella Tuscano, Angela Amato

Published Oct 23, 2013 · Vol. 5, No. 3 · pp. 613-633

Keywords: Keywords: Adipose-derived Mesenchymal Stem Cells (ASCs), Breast Cancer, HGF/c-Met crosstalk, Microenvironment, Neoangiogenesis

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles Research Paper

Kerstin Menck, Florian Klemm, Julia Christina Gross, Tobias Pukrop, Dirk Wenzel, Claudia Binder

Published Oct 21, 2013 · Vol. 4, No. 11 · pp. 2057-2066

Keywords: Breast cancer, exosomes, Evi, microvesicles, macrophages, Wnt 5a

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Sabine Becker-Weimann, Gaofeng Xiong, Saori Furuta, Ju Han, Irene Kuhn, Uri-David Akavia, Dana Pe'er, Mina J. Bissell, Ren Xu

Published Oct 14, 2013 · Vol. 4, No. 11 · pp. 2010-2020

Keywords: disorganization gene signature, p65, RelB, three-dimensional tissue structure, tissue polarity

Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector Research Paper

Franco Venanzi, Victor Shifrin, Michael Y. Sherman, Vladimir Gabai, Oleg Kisilev, Andrey Komissarov, Mikhail Grudinin, Maria Shartakova, Ekaterina Romanovskaya-Romanko, Yuri Kudryavets, Natalya Bezdenezhnykh, Oleksandra Lykhova, Nadiia Semesyuk, Antonio Concetti, Anatoly Tsyb, Marina Filimonova, Victoria Makarchuk, Raisa Yakubovsky, Andrey Chursov, Vita Shcherbinina, Alexander Shneider

Published Oct 2, 2013 · Vol. 4, No. 10 · pp. 1829-1835

Keywords: cancer immunotherapy, DNA vaccine, autophagy, metastases

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Jing Liu, Aimin Xu, Karen Siu-Ling Lam, Nai-Sum Wong, Jie Chen, Peter R R Shepherd, Yu Wang

Published Oct 1, 2013 · Vol. 4, No. 10 · pp. 1804-1818

Keywords: Adiponectin, breast cancer, autophagy, cholesterol, LDLR

Identification of novel small molecule inhibitors of centrosome clustering in cancer cells Research Paper

Eiko Kawamura, Andrew B. Fielding, Nagarajan Kannan, Aruna Balgi, Connie J. Eaves, Michel Roberge, Shoukat Dedhar

Published Sep 25, 2013 · Vol. 4, No. 10 · pp. 1763-1776

Keywords: centrosome clustering, multipolar mitosis, small molecule, cancer specific, spindle

Estrogen response in luminal breast cancer Editorial Materials

Leticia B A Rangel, Tim Hui-Ming Huang

Published Sep 21, 2013 · Vol. 4, No. 10 · pp. 1548-1549

Keywords: Distant estrogen response element (DERE), luminal breast cancer

CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations Research Paper

Roxana S Redis, Anieta M Siewerts, Maxime P Look, Oana Tudoran, Cristina Ivan, Riccardo Spizzo, Xinna Zhang, Vanja de Weerd, Masayoshi Shimizu, Hui Ling, Rares Buiga, Victor Pop, Alexandru Irimie, Riccardo Fodde, Isabella Bedrosian, John WM Martens, John A Foekens, Ioana Berindan-Neagoe, George A Calin

Published Sep 18, 2013 · Vol. 4, No. 10 · pp. 1748-1762

Keywords: non coding RNA, CCAT2, breast cancer, prognosis, real-time PCR

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

Sandra Cascio, Adam M Farkas, Rebecca P Hughey, Olivera J Finn

Published Sep 7, 2013 · Vol. 4, No. 10 · pp. 1686-1697

Keywords: MUC1, CIN85, protein-protein interaction, cell migration, metastasis, novel targets, glycosylation

The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway Research Paper

Georgios Pampalakis, Osahon Obasuyi, Olga Papadodima, Aristotelis Chatziioannou, Vassileios Zoumpourlis, Georgia Sotiropoulou

Published Sep 3, 2013 · Vol. 5, No. 9 · pp. 2390-2403

Keywords: Kallikrein-related peptidase 5 (KLK5), breast cancer, mevalonate pathway, oncogenic signaling

HER4 expression status correlates with improved outcome in both neoadjuvant and adjuvant Trastuzumab treated invasive breast carcinoma Research Paper

Bryce P Portier, Eugen C. Minca, Zhen Wang, Christopher Lanigan, Aaron M. Gruver, Erinn Downs-Kelly, G. Thomas Budd, Raymond R. Tubbs

Published Aug 26, 2013 · Vol. 4, No. 10 · pp. 1662-1672

Keywords: Breast carcinoma, HER2, HER4, Immunohistochemistry, RT-qPCR, Trastuzumab, H-Score

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Silvia Cufi, Bruna Corominas-Faja, Eugeni Lopez-Bonet, Rosa Bonavia, Sonia Pernas, Isabel Alvarez Lopez, Joan Dorca, Susana Martinez, Norberto Batista Lopez, Severina Dominguez Martinez, Elisabet Cuyas, Joana Visa, Esther Rodriguez-Gallego, Rosa Quirantes-Pine, Antonio Segura-Carretero, Jorge Joven, Begona Martin-Castillo, Javier A Menendez

Published Aug 21, 2013 · Vol. 4, No. 9 · pp. 1484-1495

Keywords: Metformin, cancer, PI3K, PIK3CA mutations, dietary restriction, calorie restriction, rapamycin

Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion Research Paper

Eva RietkÃ¶tter, Kerstin Menck, Annalen Bleckmann, Katja Farhat, Meike Schaffrinski, Matthias Schulz, Uwe-Karsten Hanisch, Claudia Binder, Tobias Pukrop

Published Aug 19, 2013 · Vol. 4, No. 9 · pp. 1449-1460

Keywords: Zoledronic acid, macrophages, microglia, metastasis, tumor microenvironment

Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression Research Paper

Alberto Gualtieri, Federica Andreola, Ilaria Sciamanna, Paola Sinibaldi Vallebona, Annalucia Serafino, Corrado Spadafora

Published Aug 9, 2013 · Vol. 4, No. 11 · pp. 1882-1893

Keywords: LINE-1 retrotransposons, SINE retrotransposons, reverse transcriptase, copy number amplification, breast cancer progression

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European Cancer and Oncology Congress

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Mouse models and anti-HER2 therapies News and Commentaries

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Research Paper

Chemokines in tumor progression and metastasis Review

SCF^Î²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms Research Paper

Adipose-derived mesenchymal stem cells (ASCs) may favour breast cancer recurrence via HGF/c-Met signaling. Research Paper

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles Research Paper

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Identification of novel small molecule inhibitors of centrosome clustering in cancer cells Research Paper

Estrogen response in luminal breast cancer Editorial Materials

CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations Research Paper

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway Research Paper

HER4 expression status correlates with improved outcome in both neoadjuvant and adjuvant Trastuzumab treated invasive breast carcinoma Research Paper

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion Research Paper

Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Mouse models and anti-HER2 therapies News and Commentaries

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Research Paper

Chemokines in tumor progression and metastasis Review

SCFÎ²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms Research Paper

Adipose-derived mesenchymal stem cells (ASCs) may favour breast cancer recurrence via HGF/c-Met signaling. Research Paper

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles Research Paper

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Identification of novel small molecule inhibitors of centrosome clustering in cancer cells Research Paper

Estrogen response in luminal breast cancer Editorial Materials

CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations Research Paper

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

The KLK5 protease suppresses breast cancer by repressing the mevalonate pathway Research Paper

HER4 expression status correlates with improved outcome in both neoadjuvant and adjuvant Trastuzumab treated invasive breast carcinoma Research Paper

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion Research Paper

Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression Research Paper

SCF^Î²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper