The Oncosearch | Oncotarget

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Salvatore Lopez, Emanuele Perrone, Stefania Bellone, Elena Bonazzoli, Burak Zeybek, Chanhee Han, Joan Tymon-Rosario, Gary Altwerger, Gulden Menderes, Anna Bianchi, Luca Zammataro, Aranzazu Manzano, Paola Manara, Elena Ratner, Dan-Arin Silasi, Gloria S. Huang, Masoud Azodi, Peter E. Schwartz, Francesco Raspagliesi, Roberto Angioli, Natalia Buza, Pei Hui, Heather M. Bond, Alessandro D. Santin

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 560-570

Keywords: sacituzumab govitecan, IMMU-132, uterine carcinosarcoma, trop-2

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Manish Charan, Piyush Dravid, Maren Cam, Bhuvana Setty, Ryan D. Roberts, Peter J. Houghton, Hakan Cam

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 510-522

Keywords: pre-metastatic niche formation, osteosarcoma, ANGPTL2, tumor microenvironment, neutrophils

Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas Research Paper

Chie Nakashima, Kazuhiko Yamamoto, Shingo Kishi, Takamitsu Sasaki, Hitoshi Ohmori, Rina Fujiwara-Tani, Shiori Mori, Isao Kawahara, Yukiko Nishiguchi, Takuya Mori, Masuo Kondoh, Yi Luo, Tadaaki Kirita, Hiroki Kuniyasu

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 309-321

Keywords: clostridium perfringens enterotoxin, claudin-4, YAP, Hippo signal, oral squamous cell carcinoma, Pathology

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models Research Paper

Hannah M. Hollandsworth, Siamak Amirfakhri, Filemoni Filemoni, Verena Schmitt, Gunther Wennemuth, Alexej Schmidt, Robert M. Hoffman, Bernhard B. Singer, Michael Bouvet

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 429-439

Keywords: carcinoembryonic antigen, CEACAM, colon cancer, fluorescence, near-infrared

Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models Research Paper

Tal Feldman, Iris Grossman-Haham, Yoav Elkis, Patrick Vilela, Neta Moskovits, Iris Barshack, Tomer M. Salame, Deborah Fass, Tal Ilani

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 386-398

Keywords: monoclonal antibody inhibitor, tumor microenvironment, fibroblasts, extracellular matrix remodeling, disulfide bonds

Systemic oncolytic adenovirus delivered in mesenchymal carrier cells modulate tumor infiltrating immune cells and tumor microenvironment in mice with neuroblastoma Research Paper

Lidia Franco-Luzón, África González-Murillo, Cristina Alcántara-Sánchez, Lorena García-García, Maryam Tabasi, Ana Luis Huertas, Louis Chesler, Manuel Ramírez

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 347-361

Keywords: oncolytic virotherapy, neuroblastoma, mesenchymal stem cells, tumor microenvironment, immune response

Immune system and bone microenvironment: rationale for targeted cancer therapies Review

Gnoni Antonio, Brunetti Oronzo, Longo Vito, Calabrese Angela, Argentiero Antonel-la, Calbi Roberto, Solimando Antonio Giovanni, Licchetta Antonella

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 480-487

Keywords: antiandrogens, bisphosphonates, bone niche, immune system, osteoimmunology

Correction: JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells Correction

Bo Tang, Guangying Qi, Fang Tang, Shengguang Yuan, Zhenran Wang, Xingsi Liang, Bo Li, Shuiping Yu, Jie Liu, Qi Huang, Yangchao Wei, Run Zhai, Biao Lei, Hongping Yu, Xingyuan Jiao, Songqing He

Published Jan 26, 2020 · Vol. 11, No. 19 · pp. 1797-1798

Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice Research Paper

Harshul Pandit, Yan Li, Qianqian Zheng, Wei Guo, Youxi Yu, Suping Li, Robert C.G. Martin

Published Jan 17, 2020 · Vol. 11, No. 22 · pp. 2047-2060

Keywords: hepatocellular carcinoma, Wnt/β-catenin signaling, cancer stem cells, epithelial cell adhesion molecule (EpCAM), tumor-initiating cells

Correction: Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo Correction

Songping Zheng, Yongzhong Cheng, Yan Teng, Xiaoxiao Liu, Ting Yu, Yi Wang, Jiagang Liu, Yuzhu Hu, Cong Wu, Xiang Wang, Yanhui Liu, Chao You, Xiang Gao, Yuquan Wei

Published Jan 16, 2020

Isolation and characterization of a CD34⁺ sub-clone in B-cell lymphoma Research Paper

Ayad M. Al-Katib, Abdul Shukkur Ebrahim, Mustapha Kandouz, Feras Zaiem, Ali Raufi, Salah Ebrahim, Anwar Mohamed, Nada Emara, Ali M. Gabali

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 148-160

Keywords: CD34, B-cell non-Hodgkin’s lymphoma, minimal residual disease, lymphoma stem cell

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

Klara Fodor, Nikoletta Dobos, Andrew Schally, Zita Steiber, Gabor Olah, Eva Sipos, Lorant Szekvolgyi, Gabor Halmos

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 175-187

Keywords: uveal melanoma, luteinizing hormone-releasing hormone (LHRH) receptor, angiogenesis, MASPIN/SERPINB5, AEZS-108 (AN-152/Zoptarelin Doxorubicin Acetate)

KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer Research Paper

Keisuke Taniuchi, Mitsunari Ogasawara

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 131-147

Keywords: RNA-binding protein, small nucleolar RNA, pancreatic cancer, cell invasion, metastasis

A novel function of AAA-ATPase p97/VCP in the regulation of cell motility Research Paper

Zi-Jia Khong, Soak-Kuan Lai, Cheng-Gee Koh, Susana Geifman-Shochat, Hoi-Yeung Li

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 74-85

Keywords: p97/VCP, AAA-ATPase, ROCK, RhoA, cell motility

KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer Research Paper

Keisuke Taniuchi, Mitsunari Ogasawara

Published Dec 24, 2019

Keywords: RNA-binding protein, small nucleolar RNA, pancreatic cancer, cell invasion, metastasis

ISG15 induction is required during L1-mediated colon cancer progression and metastasis Research Paper

Sanith Cheriyamundath, Sayon Basu, Gal Haase, Harry Doernberg, Nancy Gavert, Thomas Brabletz, Avri Ben-Ze’ev

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7122-7131

Keywords: ISG15, L1, colorectal cancer, metastasis

Efficacy of a third-generation oncolytic herpes simplex virus in neuroendocrine tumor xenograft models Research Paper

Hideyuki Matsushima, Masaki Kaibori, Masahiko Hatta, Morihiko Ishizaki, Richi Nakatake, Tadayoshi Okumura, Kengo Yoshii, Tomoki Todo

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7132-7141

Keywords: oncolytic virus, herpes simplex virus, neuroendocrine tumor, mouse xenograft model

HSP90 overexpression potentiates the B-cell receptor and fibroblast growth factor receptor survival signals in chronic lymphocytic leukemia cells Research Paper

Hasan Mahmud, Mariana Mendez, Bedabrata Mukhopadhyay, Jennifer Holter-Chakrabarty, Asish K. Ghosh

Published Dec 23, 2019 · Vol. 11, No. 22 · pp. 2037-2046

Keywords: CLL, HSP90, BCR, CD79a, PTPN22

A close relationship between HIF-1α expression and bone metastases in advanced NSCLC, a retrospective analysis Research Paper

Aldo Pezzuto, Giuseppe Perrone, Nicoletta Orlando, Fabrizio Citarella, Massimo Ciccozzi, Simone Scarlata, Giuseppe Tonini

Published Dec 17, 2019 · Vol. 10, No. 66 · pp. 7071-7079

Keywords: HIF-1α expression, lung cancer, bone metastases, time to progression

Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer Research Paper

Anna S. Gerdtsson, Jana-Aletta Thiele, Stephanie N. Shishido, Serena Zheng, Randolph Schaffer, Kelly Bethel, Steven Curley, Heinz-Josef Lenz, Diana L. Hanna, Jorge Nieva, Anand Kolatkar, Carmen Ruiz, Mariam Rodriguez-Lee, Gerard J. Oakley III, Jerry S.H. Lee, James Hicks, Peter Kuhn

Published Dec 17, 2019 · Vol. 10, No. 66 · pp. 7016-7030

Keywords: single cell analysis, liquid biopsy, metastatic colorectal cancer, circulating tumor cells, cytomorphology

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Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas Research Paper

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models Research Paper

Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models Research Paper

Systemic oncolytic adenovirus delivered in mesenchymal carrier cells modulate tumor infiltrating immune cells and tumor microenvironment in mice with neuroblastoma Research Paper

Immune system and bone microenvironment: rationale for targeted cancer therapies Review

Correction: JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells Correction

Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice Research Paper

Correction: Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo Correction

Isolation and characterization of a CD34⁺ sub-clone in B-cell lymphoma Research Paper

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer Research Paper

A novel function of AAA-ATPase p97/VCP in the regulation of cell motility Research Paper

KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer Research Paper

ISG15 induction is required during L1-mediated colon cancer progression and metastasis Research Paper

Efficacy of a third-generation oncolytic herpes simplex virus in neuroendocrine tumor xenograft models Research Paper

HSP90 overexpression potentiates the B-cell receptor and fibroblast growth factor receptor survival signals in chronic lymphocytic leukemia cells Research Paper

A close relationship between HIF-1α expression and bone metastases in advanced NSCLC, a retrospective analysis Research Paper

Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas Research Paper

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models Research Paper

Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models Research Paper

Systemic oncolytic adenovirus delivered in mesenchymal carrier cells modulate tumor infiltrating immune cells and tumor microenvironment in mice with neuroblastoma Research Paper

Immune system and bone microenvironment: rationale for targeted cancer therapies Review

Correction: JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells Correction

Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice Research Paper

Correction: Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo Correction

Isolation and characterization of a CD34+ sub-clone in B-cell lymphoma Research Paper

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer Research Paper

A novel function of AAA-ATPase p97/VCP in the regulation of cell motility Research Paper

KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer Research Paper

ISG15 induction is required during L1-mediated colon cancer progression and metastasis Research Paper

Efficacy of a third-generation oncolytic herpes simplex virus in neuroendocrine tumor xenograft models Research Paper

HSP90 overexpression potentiates the B-cell receptor and fibroblast growth factor receptor survival signals in chronic lymphocytic leukemia cells Research Paper

A close relationship between HIF-1α expression and bone metastases in advanced NSCLC, a retrospective analysis Research Paper

Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer Research Paper

Isolation and characterization of a CD34⁺ sub-clone in B-cell lymphoma Research Paper