The Oncosearch | Oncotarget

Obinutuzumab (GA101) vs. rituximab significantly enhances cell death, antibody-dependent cytotoxicity and improves overall survival against CD20+ primary mediastinal B-cell lymphoma (PMBL) in a xenograft NOD-scid IL2Rgnull (NSG) mouse model: a potential targeted agent in the treatment of PMBL Research Paper

Yaya Chu, Aradhana Awasthi, Sanghoon Lee, Dina Edani, Changhong Yin, Jessica Hochberg, Tishi Shah, Tae-Hoon Chung, Janet Ayello, Carmella van de Ven, Christian Klein, Dean Lee, Mitchell S. Cairo

Published Jul 21, 2020 · Vol. 11, No. 32 · pp. 3035-3047

Keywords: Obinutuzumab, rituximab, survival, primary mediastinal large B-cell lymphoma, antibody-dependent cellular cytotoxicity

The NKL-code for innate lymphoid cells reveals deregulated expression of NKL homeobox genes HHEX and HLX in anaplastic large cell lymphoma (ALCL) Research Paper

Stefan Nagel, Claudia Pommerenke, Roderick A.F. MacLeod, Corinna Meyer, Maren Kaufmann, Hans G. Drexler

Published Jul 15, 2020 · Vol. 11, No. 34 · pp. 3208-3226

Keywords: homeobox, NKL-code, T-ALL, LL-100, Th17

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Glenson Samuel, Jennifer Crow, Jon B. Klein, Michael L. Merchant, Emily Nissen, Devin C. Koestler, Kris Laurence, Xiaobo Liang, Kathleen Neville, Vincent Staggs, Atif Ahmed, Safinur Atay, Andrew K. Godwin

Published Jul 7, 2020 · Vol. 11, No. 31 · pp. 2995-3012

Keywords: Ewing sarcoma, EWS-ETS, biomarkers, extracellular vesicles, exosomes

Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance via immunosuppressive miR-182/miR-217 signaling and p27/CDK6 regulation Research Paper

Kalliopi Domvri, Savvas Petanidis, Doxakis Anestakis, Konstantinos Porpodis, Chong Bai, Paul Zarogoulidis, Lutz Freitag, Wolfgang Hohenforst-Schmidt, Theodora Katopodi

Published Jul 1, 2020 · Vol. 11, No. 29 · pp. 2847-2862

Keywords: PCAT-1, miR-182, immunosuppression, Kras, miR-217

Working together for the family: determination of HER oncogene co-amplifications in breast cancer Research Paper

Sergio Laurito, María Teresita Branham, Emanuel Campoy, Sebastián Real, Juan Cueto, Guillermo Urrutia, Francisco Gago, Olga Tello, Telma Glatstein, Paola De la Iglesia, Lilit Atanesyan, Suvi Savola, Maria Roqué

Published Jun 29, 2020 · Vol. 11, No. 28 · pp. 2774-2792

Keywords: HER oncogenes, breast cancer, MLPA, digital PCR, co-amplification

Can Denosumab be used in combination with Doxorubicin in Osteosarcoma? Research Paper

Francesca Punzo, Chiara Tortora, Maura Argenziano, Daniela Di Pinto, Elvira Pota, Martina Di Martino, Alessandra Di Paola, Francesca Rossi

Published Jun 27, 2020 · Vol. 11, No. 28 · pp. 2763-2773

Keywords: osteosarcoma, Denosumab, Doxorubicin, RANK-L, bone mass loss

Therapeutic efficacy of liposomal Grb2 antisense oligodeoxynucleotide (L-Grb2) in preclinical models of ovarian and uterine cancer Research Paper

Olivia D. Lara, Emine Bayraktar, Paola Amero, Shaolin Ma, Cristina Ivan, Wei Hu, Ying Wang, Lingegowda S. Mangala, Prasanta Dutta, Pratip Bhattacharya, Ana Tari Ashizawa, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo, Anil K. Sood

Published Jun 24, 2020 · Vol. 11, No. 29 · pp. 2819-2833

Keywords: ovarian cancer, nucleic-acid based therapeutics, therapeutic approaches, uterine cancer

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

Abhay Kumar Singh, Vaishali Kapoor, Dinesh Thotala, Dennis E. Hallahan

Published Jun 22, 2020 · Vol. 11, No. 27 · pp. 2647-2659

Keywords: TAF15, radiation inducible, lung cancer, antibody

Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter Research Paper

Rive Sarfstein, Haim Werner

Published Jun 9, 2020 · Vol. 11, No. 25 · pp. 2424-2437

Keywords: insulin, insulin-like growth factor-1 (IGF1), insulin receptor, IGF1 receptor, p53

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Joshua T. Rose, Eliana Moskovitz, Joseph R. Boyd, Jonathan A. Gordon, Nicole A. Bouffard, Andrew J. Fritz, Anuradha Illendula, John H. Bushweller, Jane B. Lian, Janet L. Stein, Sayyed K. Zaidi, Gary S. Stein

Published May 30, 2020 · Vol. 11, No. 26 · pp. 2512-2530

Keywords: mammary epithelial phenotype, epithelial phenotype, RUNX1, CBFβ, mitotic gene bookmarking

Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity Research Paper

Sumit Bhattacharyya, Leo Feferman, Xiaorui Han, Ke Xia, Fuming Zhang, Robert J. Linhardt, Joanne K. Tobacman

Published May 28, 2020 · Vol. 11, No. 24 · pp. 2327-2344

Keywords: sulfotransferase, sulfatase, chondroitin sulfate, Wnt, EMT

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

Hee-Don Chae, Ritika Dutta, Bruce Tiu, Fieke W. Hoff, Benedetta Accordi, Valentina Serafin, Minyoung Youn, Min Huang, Nathan Sumarsono, Kara L. Davis, Norman J. Lacayo, Martina Pigazzi, Terzah M. Horton, Steven M. Kornblau, Kathleen M. Sakamoto

Published May 26, 2020 · Vol. 11, No. 25 · pp. 2387-2403

Keywords: acute myeloid leukemia, BI-D1870, RSK, vincristine, spindle assembly checkpoint

SUSD2 expression correlates with decreased metastasis and increased survival in a high-grade serous ovarian cancer xenograft murine model Research Paper

Jordan N. Sheets, Mitch E. Patrick, Kristi A. Egland

Published May 25, 2020 · Vol. 11, No. 24 · pp. 2290-2301

Keywords: high-grade serous ovarian cancer, SUSD2, xenograft, metastasis

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Nicholas J. Monteleone, Carol S. Lutz

Published May 22, 2020 · Vol. 11, No. 26 · pp. 2464-2483

Keywords: miR-708-5p, miR-708, lung cancer, COX-2, mPGES-1

Efficacy of osimertinib against EGFRvIII+ glioblastoma Research Paper

Gustavo Chagoya, Shawn G. Kwatra, Cory W. Nanni, Callie M. Roberts, Samantha M. Phillips, Sarah Nullmeyergh, Samuel P. Gilmore, Ivan Spasojevic, David L. Corcoran, Christopher C. Young, Karla V. Ballman, Rohan Ramakrishna, Darren A. Cross, James M. Markert, Michael Lim, Mark R. Gilbert, Glenn J. Lesser, Madan M. Kwatra

Published May 5, 2020 · Vol. 11, No. 22 · pp. 2074-2082

Keywords: EGFRvIII, tyrosine kinase, glioblastoma stem cells, osimertinib, xenografts

Hereditary pancreatitis model by blastocyst complementation in mouse Research Paper

Ayumu Asai, Masamitsu Konno, Koichi Kawamoto, Ayako Isotani, Masaki Mori, Hidetoshi Eguchi, Yuichiro Doki, Takahiro Arai, Hideshi Ishii

Published May 2, 2020 · Vol. 11, No. 22 · pp. 2061-2073

Keywords: blastocyst complementation, hereditary pancreatitis, disease-specific pluripotent stem cells, PRSS1

The prognostic significance of GRB7 protein expression and localization in human breast and ovarian cancers Research Paper

Anke Vermehren-Schmaedick, Paulette Mhawech-Fauceglia, Byung S. Park, Tanja Pejovic, Shiuh-Wen Luoh

Published May 1, 2020 · Vol. 11, No. 24 · pp. 2273-2289

Keywords: GRB7 expression, breast cancer, ovarian cancer, immunohistochemistry, prognosis

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Carmen J. Narvaez, Erika LaPorta, Samantha Robilotto, Jennifer Liang, JoEllen Welsh

Published Apr 25, 2020 · Vol. 11, No. 30 · pp. 2889-2905

Keywords: vitamin D, hyaluronic acid, hyaluronan synthase, HAS2, breast cancer

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

Suparna Mazumder, Valerie Swank, Anton A. Komar, Justin M. Johnson, Vincent K. Tuohy

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1894-1910

Keywords: monoclonal antibody, anti-Müllerian hormone receptor type II, immunotherapy, ovarian cancer, 4D12G1

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Haleema Saeed, Sayantani Sinha, Christine Mella, Jeffrey S. Kuerbitz, Monica L. Cales, Mark A. Steele, Jennifer Stanke, Derek Damron, Fayez Safadi, Steven J. Kuerbitz

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1876-1893

Keywords: osteosarcoma, DNA methylation, neuronatin, tumor suppressor genes

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

The NKL-code for innate lymphoid cells reveals deregulated expression of NKL homeobox genes HHEX and HLX in anaplastic large cell lymphoma (ALCL) Research Paper

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance via immunosuppressive miR-182/miR-217 signaling and p27/CDK6 regulation Research Paper

Working together for the family: determination of HER oncogene co-amplifications in breast cancer Research Paper

Can Denosumab be used in combination with Doxorubicin in Osteosarcoma? Research Paper

Therapeutic efficacy of liposomal Grb2 antisense oligodeoxynucleotide (L-Grb2) in preclinical models of ovarian and uterine cancer Research Paper

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter Research Paper

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity Research Paper

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

SUSD2 expression correlates with decreased metastasis and increased survival in a high-grade serous ovarian cancer xenograft murine model Research Paper

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Efficacy of osimertinib against EGFRvIII+ glioblastoma Research Paper

Hereditary pancreatitis model by blastocyst complementation in mouse Research Paper

The prognostic significance of GRB7 protein expression and localization in human breast and ovarian cancers Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The NKL-code for innate lymphoid cells reveals deregulated expression of NKL homeobox genes HHEX and HLX in anaplastic large cell lymphoma (ALCL) Research Paper

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers Research Paper

Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance via immunosuppressive miR-182/miR-217 signaling and p27/CDK6 regulation Research Paper

Working together for the family: determination of HER oncogene co-amplifications in breast cancer Research Paper

Can Denosumab be used in combination with Doxorubicin in Osteosarcoma? Research Paper

Therapeutic efficacy of liposomal Grb2 antisense oligodeoxynucleotide (L-Grb2) in preclinical models of ovarian and uterine cancer Research Paper

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter Research Paper

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity Research Paper

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

SUSD2 expression correlates with decreased metastasis and increased survival in a high-grade serous ovarian cancer xenograft murine model Research Paper

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Efficacy of osimertinib against EGFRvIII+ glioblastoma Research Paper

Hereditary pancreatitis model by blastocyst complementation in mouse Research Paper

The prognostic significance of GRB7 protein expression and localization in human breast and ovarian cancers Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D3 in breast cancer Research Paper

Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper