The Oncosearch | Oncotarget

Systemic oncolytic adenovirus delivered in mesenchymal carrier cells modulate tumor infiltrating immune cells and tumor microenvironment in mice with neuroblastoma Research Paper

Lidia Franco-Luzón, África González-Murillo, Cristina Alcántara-Sánchez, Lorena García-García, Maryam Tabasi, Ana Luis Huertas, Louis Chesler, Manuel Ramírez

Published Dec 12, 2019

Keywords: oncolytic virotherapy, neuroblastoma, mesenchymal stem cells, tumor microenvironment, immune response

Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a Research Paper

Sweta Sikder, Sujata Kumari, Manoj Kumar, Shrinka Sen, Namrata Bora Singhal, Srikumar Chellappan, Mukul Godbole, Pratik Chandrani, Amit Dutt, Kodaganur S. Gopinath, Tapas K. Kundu

Published Dec 3, 2019 · Vol. 10, No. 64 · pp. 6855-6869

Keywords: tumour suppressor, non-histone chromatin protein, oncomiR, matrix metalloproteinases, p53 activation

Post-translational modifications of vimentin reflect different pathological processes associated with non-small cell lung cancer and chronic obstructive pulmonary disease Research Paper

Neel Ingemann Nissen, Morten Karsdal, Nicholas Willumsen

Published Nov 26, 2019 · Vol. 10, No. 63 · pp. 6829-6841

Keywords: vimentin, NSCLC, COPD, liquid biopsies, biomarkers

Targeted enhancement of the therapeutic window of L19-TNF by transient and selective inhibition of RIPK1-signaling cascade Research Paper

Sheila Dakhel, Tiziano Ongaro, Baptiste Gouyou, Mattia Matasci, Alessandra Villa, Dario Neri, Samuele Cazzamalli

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6678-6690

Keywords: tumor targeting, antibody-cytokine fusions, targeted-tumor necrosis factor, EDB-fibronectin, intracellular RIPK1-inhibitors

Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models Research Paper

Tony Yeung, Oliver Fung, Mikhail Bashkurov, Arian Khandani, Omar Subedar, Alexandra Wudwud, Patricia Shaw, Blaise Clarke, John Bartlett, Robert Rottapel, Andras Kapus

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6691-6712

Keywords: hyperploid genome, apoptosis, platinum chemotherapy, cell cycle checkpoint, ovarian cancer

Correction: Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells Correction

Xinpei Yu, Junkui Ai, Liquan Cai, Yifeng Jing, Dan Wang, Jun Dong, Laura E. Pascal, Jian Zhang, Rongcheng Luo, Zhou Wang

Published Nov 16, 2019 · Vol. 10, No. 67 · pp. 7181-7182

High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target Research Paper

Guilhem Bousquet, Jean-Paul Feugeas, Yuchen Gu, Christophe Leboeuf, Morad El Bouchtaoui, He Lu, Marc Espié, Anne Janin, Melanie Di Benedetto

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6577-6588

Keywords: triple-negative breast cancer, chemotherapy resistance, apoptosis-inhibitor-5, peptide, anti-angiogenic therapy

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

Chunmei Zhao, Benjamin J. Thompson, Kelly Chen, Feng Gao, Barbara Blouw, Mathieu Marella, Susan Zimmerman, Trevor Kimbler, Sheryl Garrovillo, Jesse Bahn, Lei Huang, Zhongdong Huang, H. Michael Shepard, Sanna Rosengren, Christopher D. Thanos, Daniel C. Maneval

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6561-6576

Keywords: hyaluronan, breast cancer, xenograft, tumor microenvironment, CD44

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications Research Paper

Albert D. Donnenberg, James D. Luketich, Vera S. Donnenberg

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6456-6465

Keywords: pleural effusion, non-small cell lung cancer, malignant mesothelioma, cytokines, IL-6

Characterizing CD44 regulatory microRNAs as putative therapeutic agents in human melanoma Research Paper

Johannes Fänder, Heike Kielstein, Maximilian Büttner, Peter Koelblinger, Reinhard Dummer, Marcus Bauer, Diana Handke, Claudia Wickenhauser, Barbara Seliger, Simon Jasinski-Bergner

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6509-6525

Keywords: CD44, CD44v6, melanoma, microRNA, immune cell infiltration

A negative feedback regulatory loop between miR-138 and TP53 is mediated by USP10 Priority Research Paper

Zhenghua Luo, Manchao Zhang, Ri Cui, Esmerina Tili, Taewan Kim, Tae Jin Lee, Yong Peng, Carlo Croce

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6288-6296

Keywords: TP53, USP10, miR-138

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer Research Paper

C. Andrew Boswell, Daniela Bumbaca Yadav, Eduardo E. Mundo, Shang-Fan Yu, Jennifer Arca Lacap, Aimee Fourie-O’Donohue, Katherine R. Kozak, Gregory Z. Ferl, Crystal Zhang, Jason Ho, Sheila Ulufatu, Leslie A. Khawli, Kedan Lin

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6234-6244

Keywords: antibody-drug conjugate, prostate cancer, pharmacokinetics, TENB2, imaging

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells Research Paper

Channay Naidoo, Cherie Ann Kruger, Heidi Abrahamse

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6079-6095

Keywords: metastatic melanoma, nano active targeting, zinc phthalocyanine tetra-sulphonic acid, photodynamic therapy

The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients Research Paper

Aarash K. Roshandel, Christopher M. Busch, Jennifer Van Mullekom, Joshua A. Cuoco, Cara M. Rogers, Lisa S. Apfel, Eric A. Marvin, Harald W. Sontheimer, Robyn A. Umans

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6204-6218

Keywords: p53, TP53, immunohistochemistry, gene sequencing, glioblastoma multiforme

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

Manti Guha, Satish Srinivasan, Maura M. Sheehan, Takashi Kijima, Gordon Ruthel, Kelly Whelan, Koji Tanaka, Andres Klein-Szanto, Prasanna M. Chandramouleeswaran, Hiroshi Nakagawa, Narayan G. Avadhani

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6245-6259

Keywords: mitochondrial DNA, MPV17, ESCC, telomere, 3D organoid

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Prachi Namjoshi, Lori Showalter, Brian J. Czerniecki, Gary K. Koski

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 6006-6020

Keywords: apoptosis, HER-2, T-helper 1, IFN-γ, TNF-α

Epigenetic silencing of HOPX is critically involved in aggressive phenotypes and patient prognosis in papillary thyroid cancer Research Paper

Yosuke Ooizumi, Hiroshi Katoh, Mitsuo Yokota, Masahiko Watanabe, Keishi Yamashita

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5906-5918

Keywords: HOPX, papillary thyroid cancer, epigenetic silencing, promoter methylation

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

Shiho Fukui, Kazunori Nagasaka, Yuko Miyagawa, Ryoko Kikuchi-Koike, Yoshiko Kawata, Ranka Kanda, Takayuki Ichinose, Takeru Sugihara, Haruko Hiraike, Osamu Wada-Hiraike, Yuko Sasajima, Takuya Ayabe

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5932-5948

Keywords: ovarian cancer, bAP15, TGF-β/Smad signaling, UCHL5, apoptosis

Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases Research Paper

Belen Alvarez-Palomo, Carme Barrot-Feixat, Helena Sarret, Jordi Requena, Montserrat Pau, Jose-Manuel Vidal-Taboada, Rafael Oliva, Josep-Lluis Ballesca, Michael J. Edel, Jovita Mezquita-Pla

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5871-5887

Keywords: ligand-independent intracellular iVEGFR-1 isoforms, mature testis, spermiogenesis, SRC activation, fertility

GSTΠ stimulates caveolin-1-regulated polyamine uptake via actin remodeling Research Paper

Takeshi Uemura, George Tsaprailis, Eugene W. Gerner

Published Oct 1, 2019 · Vol. 10, No. 55 · pp. 5713-5723

Keywords: polyamine, caveolin, GSTπ, transport, actin

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Systemic oncolytic adenovirus delivered in mesenchymal carrier cells modulate tumor infiltrating immune cells and tumor microenvironment in mice with neuroblastoma Research Paper

Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a Research Paper

Post-translational modifications of vimentin reflect different pathological processes associated with non-small cell lung cancer and chronic obstructive pulmonary disease Research Paper

Targeted enhancement of the therapeutic window of L19-TNF by transient and selective inhibition of RIPK1-signaling cascade Research Paper

Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models Research Paper

Correction: Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells Correction

High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target Research Paper

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications Research Paper

Characterizing CD44 regulatory microRNAs as putative therapeutic agents in human melanoma Research Paper

A negative feedback regulatory loop between miR-138 and TP53 is mediated by USP10 Priority Research Paper

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer Research Paper

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells Research Paper

The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients Research Paper

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Epigenetic silencing of HOPX is critically involved in aggressive phenotypes and patient prognosis in papillary thyroid cancer Research Paper

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases Research Paper

GSTΠ stimulates caveolin-1-regulated polyamine uptake via actin remodeling Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Systemic oncolytic adenovirus delivered in mesenchymal carrier cells modulate tumor infiltrating immune cells and tumor microenvironment in mice with neuroblastoma Research Paper

Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a Research Paper

Post-translational modifications of vimentin reflect different pathological processes associated with non-small cell lung cancer and chronic obstructive pulmonary disease Research Paper

Targeted enhancement of the therapeutic window of L19-TNF by transient and selective inhibition of RIPK1-signaling cascade Research Paper

Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models Research Paper

Correction: Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells Correction

High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target Research Paper

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications Research Paper

Characterizing CD44 regulatory microRNAs as putative therapeutic agents in human melanoma Research Paper

A negative feedback regulatory loop between miR-138 and TP53 is mediated by USP10 Priority Research Paper

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer Research Paper

Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells Research Paper

The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients Research Paper

Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Epigenetic silencing of HOPX is critically involved in aggressive phenotypes and patient prognosis in papillary thyroid cancer Research Paper

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases Research Paper

GSTΠ stimulates caveolin-1-regulated polyamine uptake via actin remodeling Research Paper

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper