The Oncosearch | Oncotarget

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

Diana Barea Roldán, Matthias Grimmler, Christoph Hartmann, Stefanie Hubich-Rau, Tim Beißert, Claudia Paret, Giuseppe Cagna, Christoph Rohde, Stefan Wöll, Michael Koslowski, Özlem Türeci, Ugur Sahin

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1862-1875

Keywords: PLAC1, tumorigenesis, extracellular matrix, fibroblast growth factor, AKT

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Leanne Milton-Harris, Mark Jeeves, Sarah A. Walker, Simon E. Ward, Erika J. Mancini

Published Apr 22, 2020 · Vol. 11, No. 19 · pp. 1737-1748

Keywords: protein-protein interaction, leukaemia, T-ALL, drug discovery, LMO2

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Haleema Saeed, Sayantani Sinha, Christine Mella, Jeffrey S. Kuerbitz, Monica L. Cales, Mark A. Steele, Jennifer Stanke, Derek Damron, Fayez Safadi, Steven J. Kuerbitz

Published Apr 22, 2020

Keywords: osteosarcoma, DNA methylation, neuronatin, tumor suppressor genes

Graded expression of microRNA-371a-3p in tumor tissues, contralateral testes, and in serum of patients with testicular germ cell tumor Research Paper

Gazanfer Belge, Finja Hennig, Cansu Dumlupinar, Francesca Grobelny, Klaus Junker, Arlo Radtke, Klaus-Peter Dieckmann

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1462-1473

Keywords: testicular germ cell tumors, microRNA-371a-3p, serum, contralateral testes, in situ hybridization

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Abhijit Chakraborty, Faisal Aziz, Eunmiri Roh, Le Thi My Le, Raja Dey, Tianshun Zhang, Moeez G. Rathore, Aalekhya Sharma Biswas, Ann M. Bode, Zigang Dong

Published Apr 17, 2020 · Vol. 11, No. 20 · pp. 1846-1861

Keywords: TIMELESS, TIPIN, apoptosis, xenograft, Cryo-EM

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

James R. Browning, Paige Derr, Kristy Derr, Nicole Doudican, Sam Michael, Samantha R. Lish, Nicholas A. Taylor, James G. Krueger, Marc Ferrer, John A. Carucci, Daniel S. Gareau

Published Apr 16, 2020 · Vol. 11, No. 27 · pp. 2587-2596

Keywords: squamous cell carcinoma, screening, 3D printing, in vitro model, confocal microscopy

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Vijay R. Gupta, Adam Root, Timothy Fisher, Rand Norberg, John David, Tracey Clark, Justin Cohen, Chad May, Anand Giddabasappa

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1344-1357

Keywords: bispecific antibody, tumor targeting, biodistribution, T cells, molecular imaging

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Natalia V. Eremina, Vasily I. Kazey, Sergey V. Mishugin, Roman V. Leonenkov, Dmitry Y. Pushkar, Vadim L. Mett, Andrei V. Gudkov

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1273-1288

Keywords: prostate cancer, immunotherapy, mobilan, adenoviral vector, intratumor injection

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Xi Xiao, Carsten Sticht, Libo Yin, Li Liu, Svetlana Karakhanova, Yefeng Yin, Christina Georgikou, Jury Gladkich, Wolfgang Gross, Norbert Gretz, Ingrid Herr

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1203-1217

Keywords: broccoli, broccoletti, Brassica rapa sylvestris, plant microRNAs, cross-kingdom regulation

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

Asif Rashid, Xin Duan, Feng Gao, Mengsu Yang, Andrew Yen

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1017-1036

Keywords: ATRA, roscovitine, APL, HL-60, Lyn

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Souhila Abdelfettah, Gaylor Boulay, Marion Dubuissez, Nathalie Spruyt, Sara P. Garcia, Shruthi Rengarajan, Ingrid Loison, Xavier Leroy, Miguel N. Rivera, Dominique Leprince

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1051-1074

Keywords: hPCL3S, PHF19, PRC2, β-catenin, prostate cancer

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Caroline Dafflon, Swann Gaulis, Louise Barys, Karen Kapur, Vanessa Cornacchione, Lina Schukur, Sebastian Bergling, Elisabetta Traggiai, Selina Jansky, Leon Hellmann, Barbara Schacher Engstler, Grainne Kerr, Antoine de Weck, David A. Ruddy, Ulrike Naumann, Frédéric Stauffer, Christoph Gaul, Ying Lin, Eric Billy, Andreas Weiss, Francesco Hofmann, Moriko Ito, Ralph Tiedt

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 956-968

Keywords: DOT1L, multiple myeloma, epigenetics, histone methylation, unfolded protein response

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

Nicci Owusu-Brackett, Ming Zhao, Argun Akcakanat, Kurt W. Evans, Erkan Yuca, Ecaterina Ileana Dumbrava, Filip Janku, Funda Meric-Bernstam

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 969-981

Keywords: PI3Kβ, PTEN loss, AZD8186, chemotherapy, immunotherapy

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

Eduardo Listik, Leny Toma

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 828-845

Keywords: glioblastoma, glypican-1, tumorigenesis, chemotherapy resistance, temozolomide

Correction: Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Correction

David M. Goldenberg, Thomas M. Cardillo, Serengulam V. Govindan, Edmund A. Rossi, Robert M. Sharkey

Published Feb 25, 2020 · Vol. 11, No. 10 · pp. 942-942

Subcellular localization of FANCD2 is associated with survival in ovarian carcinoma Research Paper

Sonali Joshi, Shawn Campbell, Jeong Y. Lim, Shannon McWeeney, Adam Krieg, Yukie Bean, Nadja Pejovic, Paulette Mhawech-Fauceglia, Tanja Pejovic

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 775-783

Keywords: FANCD2, ovarian carcinoma, subcellular localization

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Pierre Boyé, Franck Floch, François Serres, Zacharie Segaoula, Juliette Hordeaux, Quentin Pascal, Virginie Coste, Sandy Courapied, Emmanuel Bouchaert, Agata Rybicka, Claire Mazuy, Laurent Marescaux, Kévyn Geeraert, Corinne Fournel-Fleury, Alain Duhamel, François Machuron, Pierre Ferré, Aurélie Pétain, Nicolas Guilbaud, Dominique Tierny, Bruno Gomes

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 671-686

Keywords: etoposide phosphate, F14512, non-Hodgkin lymphoma, pet dog model, P-glycoprotein

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

Ryan P. Gilley, Peter H. Dube

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 740-754

Keywords: cancer immunotherapy, cancer vaccination, checkpoint blockade, melanoma, listeria

In vitro studies on CNGRC-CPG2 fusion proteins for ligand-directed enzyme prodrug therapy for targeted cancer therapy Research Paper

Layla Al-mansoori, Sara S. Bashraheel, Alanod D. Al Qahtani, C. David O’Connor, Philip Elsinga, Sayed K. Goda

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 619-633

Keywords: targeted cancer therapy, carboxypeptidase G2, glucarpidase, ligand directed enzyme prodrug therapy, antibody directed enzyme prodrug therapy

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Richard K. Yang, Yun Qing, Fatima Zahra Jelloul, Mark J. Routbort, Peng Wang, Kenna Shaw, Jiexin Zhang, Jack Lee, L. Jeffrey Medeiros, Scott Kopetz, Michael T. Tetzlaff, Russell R. Broaddus

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 600-618

Keywords: biomarkers, immunotherapy, mutations, TMB, histology

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PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Graded expression of microRNA-371a-3p in tumor tissues, contralateral testes, and in serum of patients with testicular germ cell tumor Research Paper

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

Correction: Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Correction

Subcellular localization of FANCD2 is associated with survival in ovarian carcinoma Research Paper

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

In vitro studies on CNGRC-CPG2 fusion proteins for ligand-directed enzyme prodrug therapy for targeted cancer therapy Research Paper

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation Research Paper

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Graded expression of microRNA-371a-3p in tumor tissues, contralateral testes, and in serum of patients with testicular germ cell tumor Research Paper

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

Correction: Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Correction

Subcellular localization of FANCD2 is associated with survival in ovarian carcinoma Research Paper

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

In vitro studies on CNGRC-CPG2 fusion proteins for ligand-directed enzyme prodrug therapy for targeted cancer therapy Research Paper

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper