The Oncosearch | Oncotarget

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity Research Paper

Swapna Asuthkar, Kiran Kumar Velpula, Chandramu Chetty, Bharathi Gorantla, Jasti S. Rao

Published Nov 16, 2012 · Vol. 3, No. 11 · pp. 1439-1454

Keywords: Matrix metalloproteinase-9 (MMP-9), microRNA-211 (miR-211), Cancer Stem Cells (CSC), Ionizing radiation (IR) and Temozolomide (Tem)

Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion Kinase Research Paper

Pascale Flandrin-Gresta, Francoise Solly, Carmen Mariana Aanei, Jerome Cornillon, Emmanuelle Tavernier, Nathalie Nadal, Franck Morteux, Denis Guyotat, Eric Wattel, Lydia Campos

Published Sep 28, 2012 · Vol. 3, No. 10 · pp. 1158-1168

Keywords: HSP90, myelodysplasic syndrome, AKT, FAK

Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients Research Paper

Elias Bou Samra, Bernard Klein, ThÃ©rÃ¨se Commes, Jerome Moreaux

Published Aug 18, 2012 · Vol. 3, No. 8 · pp. 824-832

Keywords: gene expression-based risk score, cytogenetically normal-acute myeloid leukemia, prognostic gene signature, EVI1 expression

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels Research Paper

Daniela Bressanin, Camilla Evangelisti, Francesca Ricci, Giovanna Tabellini, Francesca Chiarini, Pier Luigi Tazzari, Fraia Melchionda, Francesca Buontempo, Pasqualepaolo Pagliaro, Andrea Pession, James A McCubrey, Alberto M. Martelli

Published Aug 9, 2012 · Vol. 3, No. 8 · pp. 811-823

Keywords: acute leukemia, targeted therapy, signal transduction modulators, PI3K/PDK1, vertical inhibition

Mutant IDH1 is required for IDH1 mutated tumor cell growth Brief Reports

Genglin Jin, Christopher J. Pirozzi, Lee H. Chen, Christopher G. Duncan, Giselle Y. Lopez, Jie Feng, Ivan Spasojevic, Darell D. Bigner, Yiping He, Hai Yan

Published Aug 9, 2012 · Vol. 3, No. 8 · pp. 774-782

Keywords: IDH1, cell survival

A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy Research Paper

Dipankar Pramanik, Nathaniel R Campbell, Samarjit Das, Sonal Gupta, Venugopal Chenna, Savita Bisht, Polina Sysa-shah, Djahida Bedja, Collins Karikari, Charles Steenbergen, Kathleen L. Gabrielson, Amarnath Maitra, Anirban Maitra

Published Jul 10, 2012 · Vol. 3, No. 6 · pp. 640-650

FLT3 in lineage specification and plasticity Research Perspective

Sarah Greenblatt, Donald Small

Published May 27, 2012 · Vol. 3, No. 5 · pp. 576-580

Keywords: FLT3, B220, leukemia, lineage, differentiation

Solid Tumor Differentiation Therapy â€“ Is It Possible? Research Perspective

Filemon Dela cruz, Igor Matushansky

Published May 24, 2012 · Vol. 3, No. 5 · pp. 559-567

Properties of Mechano-Transduction via Simulated Microgravity and its Effects on Intracellular Trafficking of VEGFRâ€™s Research Paper

Andrew Puca, Giuseppe Russo, Antonio Giordano

Published May 6, 2012 · Vol. 3, No. 4 · pp. 426-434

Keywords: Hematopoiesis and Stem Cells, Vascular Biology

Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment Review

Alberto M. Martelli, Francesca Chiarini, Camilla Evangelisti, Alessandra Cappellini, Francesca Buontempo, Daniela Bressanin, Milena Fini, James A. McCubrey

Published May 4, 2012 · Vol. 3, No. 4 · pp. 371-394

Keywords: apoptosis, leukemia initiating cells, mRNA translation, PI3K/Akt/mTOR, targeted therapy

AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications. Research Perspective

Leonidas Platanias, Eliza Vakana

Published Dec 31, 2011 · Vol. 2, No. 12 · pp. 1322-1328

Keywords: AMPK, mTOR, leukemia, BCR-ABL

Is human cytomegalovirus a target in cancer therapy? Research Perspective

John Inge Johnsen, Ninib Baryawno, Cecilia SÃ¶derberg-NauclÃ©r

Published Dec 31, 2011 · Vol. 2, No. 12 · pp. 1329-1338

Keywords: cancer, human cytomegalovirus

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience. Research Paper

Olivier LaRochelle, Sarah Bertoli, FranÃ§ois Vergez, Jean Emmanuel Sarry, VÃ©ronique Mansat-De Mas, Sophie Dobbelstein, Nicole Dastugue, Anne-Claire Strzelecki, Cindy Cavelier, Laurent Creancier, Arnaud Pillon, Anna Kruczynski, Cecile Demur, Audrey Sarry, FranÃ§oise Huguet, Anne Huynh, Christian RÃ©cher, Eric Delabesse

Published Nov 9, 2011 · Vol. 2, No. 11 · pp. 850-861

Keywords: leukemia, DNMT3A, anthracyclins, idarubicin, AML

Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1 Research Paper

Sally-Anne Heasman, Lyubov Zaitseva, Kristian M. Bowles, Stuart A. Rushworth, David J. MacEwan

Published Sep 9, 2011 · Vol. 2, No. 9 · pp. 658-668

Keywords: drug-resistance, antioxidant, transcription factor, apoptosis, chemotherapy

Targeting mTOR for the treatment of AML. New agents and new directions. Research Perspective

Jessica K. Altman, Antonella Sassano, Leonidas C. Platanias

Published Jun 15, 2011 · Vol. 2, No. 6 · pp. 510-517

Keywords: mTOR, leukemia, myeloid, TORC2

Mcl-1 Ubiquitination and Destruction Research Perspective

Hiroyuki Inuzuka, Hidefumi Fukushima, Shavali Shaik, Pengda Liu, Alan W. Lau, Wenyi Wei

Published Mar 19, 2011 · Vol. 2, No. 3 · pp. 239-244

Keywords: Ubiquitination, SCF, Fbw7, GSK3, Mcl-1, Apoptosis, Tumor Suppressor, Phosphorylation, Cell Cycle

Standards and Impact of Hematopathology in Myelodysplastic Syndromes (MDS) Review

Peter Valent, Attilio Orazi, Guntram BÃ¼sche, Annette Schmitt-GrÃ¤ff, Tracy I. George, Karl Sotlar, Berthold Streubel, Christine Beham-Schmid, Sabine Cerny-Reiterer, Otto Krieger, Arjan van de Loosdrecht, Wolfgang Kern, Kiyoyuki Ogata, Friedrich Wimazal, Judit Csomor, Judit VÃ¡rkonyi, Wolfgang R. Sperr, Martin Werner, Hans Kreipe, Hans-Peter Horny

Published Nov 16, 2010 · Vol. 1, No. 7 · pp. 483-496

The heme oxygenase-1 and c-FLIP in acute myeloid leukemias: two non-redundant but mutually exclusive cellular safeguards protecting cells against TNF-induced cell death? Commentary

Sarah Shirley, Olivier Micheau

Published Sep 16, 2010 · Vol. 1, No. 5 · pp. 317-319

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism Research Paper

Stuart A Rushworth, Lyubov Zaitseva, Susana Langa, Kristian M Bowles, David J MacEwan

Published Sep 13, 2010 · Vol. 1, No. 5 · pp. 359-366

What are genome-wide association studies telling us about B-cell tumor development? Research Perspective

Amy L Sherborne, Richard S Houlston

Published Sep 11, 2010 · Vol. 1, No. 5 · pp. 367-372

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Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity Research Paper

Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion Kinase Research Paper

Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients Research Paper

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels Research Paper

Mutant IDH1 is required for IDH1 mutated tumor cell growth Brief Reports

A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy Research Paper

FLT3 in lineage specification and plasticity Research Perspective

Solid Tumor Differentiation Therapy â€“ Is It Possible? Research Perspective

Properties of Mechano-Transduction via Simulated Microgravity and its Effects on Intracellular Trafficking of VEGFRâ€™s Research Paper

Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment Review

AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications. Research Perspective

Is human cytomegalovirus a target in cancer therapy? Research Perspective

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience. Research Paper

Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1 Research Paper

Targeting mTOR for the treatment of AML. New agents and new directions. Research Perspective

Mcl-1 Ubiquitination and Destruction Research Perspective

Standards and Impact of Hematopathology in Myelodysplastic Syndromes (MDS) Review

The heme oxygenase-1 and c-FLIP in acute myeloid leukemias: two non-redundant but mutually exclusive cellular safeguards protecting cells against TNF-induced cell death? Commentary

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism Research Paper

What are genome-wide association studies telling us about B-cell tumor development? Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity Research Paper

Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion Kinase Research Paper

Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients Research Paper

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels Research Paper

Mutant IDH1 is required for IDH1 mutated tumor cell growth Brief Reports

A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy Research Paper

FLT3 in lineage specification and plasticity Research Perspective

Solid Tumor Differentiation Therapy â€“ Is It Possible? Research Perspective

Properties of Mechano-Transduction via Simulated Microgravity and its Effects on Intracellular Trafficking of VEGFRâ€™s Research Paper

Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment Review

AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications. Research Perspective

Is human cytomegalovirus a target in cancer therapy? Research Perspective

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience. Research Paper

Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1 Research Paper

Targeting mTOR for the treatment of AML. New agents and new directions. Research Perspective

Mcl-1 Ubiquitination and Destruction Research Perspective

Standards and Impact of Hematopathology in Myelodysplastic Syndromes (MDS) Review

The heme oxygenase-1 and c-FLIP in acute myeloid leukemias: two non-redundant but mutually exclusive cellular safeguards protecting cells against TNF-induced cell death? Commentary

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism Research Paper

What are genome-wide association studies telling us about B-cell tumor development? Research Perspective