The Oncosearch | Oncotarget

Carbon ion irradiation enhances the antitumor efficacy of dual immune checkpoint blockade therapy both for local and distant sites in murine osteosarcoma Research Paper

Yutaka Takahashi, Tomohiro Yasui, Kazumasa Minami, Keisuke Tamari, Kazuhiko Hayashi, Keisuke Otani, Yuji Seo, Fumiaki Isohashi, Masahiko Koizumi, Kazuhiko Ogawa

Published Jan 18, 2019 · Vol. 10, No. 6 · pp. 633-646

Increased PD-L1 expression in radioresistant HNSCC cell lines after irradiation affects cell proliferation due to inactivation of GSK-3beta Research Paper

Daniela Schulz, Irene Stancev, Antonio Sorrentino, Ayse-Nur Menevse, Philipp Beckhove, Gero Brockhoff, Matthias GÃ¼nther Hautmann, Torsten Erich Reichert, Richard Josef Bauer, Tobias Ettl

Published Jan 15, 2019 · Vol. 10, No. 5 · pp. 573-583

Programmed death ligand 1 expression in early stage, resectable non-small cell lung cancer Research Paper

Manolo D'Arcangelo, Armida D'Incecco, Claudia Ligorio, Stefania Damiani, Maurizio Puccetti, Sara Bravaccini, Luigi Terracciano, Chiara Bennati, Gabriele Minuti, Silvia Vecchiarelli, Lorenza Landi, Marina Milesi, Alberto Meroni, Sara Ravaioli, Maria Maddalena Tumedei, Matteo Incarbone, Federico Cappuzzo

Published Jan 15, 2019 · Vol. 10, No. 5 · pp. 561-572

Genomic characterization of metastatic ultra-hypermutated interdigitating dendritic cell sarcoma through rapid research autopsy Research Paper

Hui-Zi Chen, Russell Bonneville, Lianbo Yu, Michele R. Wing, Julie W. Reeser, Melanie A. Krook, Jharna Miya, Eric Samorodnitsky, Amy Smith, Dorrelyn Martin, Thuy Dao, Qishan Guo, David Liebner, Aharon G. Freud, Patricia Allenby, Sameek Roychowdhury

Published Jan 8, 2019 · Vol. 10, No. 3 · pp. 277-288

Clinical characteristics, treatment outcomes and potential novel therapeutic options for patients with neuroendocrine carcinoma of the prostate Research Paper

Leonidas Apostolidis, Cathleen Nientiedt, Eva Caroline Winkler, Anne Katrin Berger, Clemens Kratochwil, Annette Kaiser, Anne-Sophie Becker, Dirk JÃ¤ger, Markus Hohenfellner, Clemens HÃ¼ttenbrink, Sascha Pahernik, Florian A. Distler, Carsten GrÃ¼llich

Published Jan 1, 2019 · Vol. 10, No. 1 · pp. 17-29

Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer Research Paper

Jayati Chakrabarti, Loryn Holokai, LiJyun Syu, Nina G. Steele, Julie Chang, Jiang Wang, Syed Ahmed, Andrzej Dlugosz, Yana Zavros

Published Dec 21, 2018 · Vol. 9, No. 100 · pp. 37439-37457

STAT1 deficiency supports PD-1/PD-L1 signaling resulting in dysfunctional TNFÎ± mediated immune responses in a model of NSCLC Research Paper

Juliane Friedrich, Lisanne Heim, Denis I. Trufa, Horia Sirbu, Ralf J. Rieker, Mircea T. Chiriac, Susetta Finotto

Published Dec 14, 2018 · Vol. 9, No. 98 · pp. 37157-37172

Correction: PD-L1 expression heterogeneity in non-small cell lung cancer: evaluation of small biopsies reliability Correction

Enrico Munari, Giuseppe Zamboni, Marcella Marconi, Marco Sommaggio, Matteo Brunelli, Guido Martignoni, George J. Netto, Francesca Moretta, Maria Cristina Mingari, Matteo Salgarello, Alberto Terzi, Vincenzo Picece, Carlo Pomari, Gianluigi Lunardi, Alberto Cavazza, Giulio Rossi, Lorenzo Moretta, Giuseppe Bogina

Published Dec 11, 2018 · Vol. 9, No. 97 · pp. 37077-37077

CD39⁺ regulatory T cells accumulate in colon adenocarcinomas and display markers of increased suppressive function Research Paper

Filip Ahlmanner, Patrik SundstrÃ¶m, Paulina Akeus, Jenny EklÃ¶f, Lars BÃ¶rjesson, Bengt Gustavsson, Elinor Bexe Lindskog, Sukanya Raghavan, Marianne Quiding-JÃ¤rbrink

Published Dec 11, 2018 · Vol. 9, No. 97 · pp. 36993-37007

Anti-PD-1 therapy for clinical treatment of lymphoma: a single-arm meta-analysis Meta-Analysis

Zhe Geng, Yi Xiao, Xiao-Jian Zhu, Cong Ye, Jian-Feng Zhou

Published Oct 19, 2018 · Vol. 9, No. 82 · pp. 35343-35355

Characterization of murine CEACAM1 in vivo reveals low expression on CD8⁺ T cells and no tumor growth modulating activity by anti-CEACAM1 mAb CC1 Research Paper

Robbie L. McLeod, Minilik H. Angagaw, Toya Nath Baral, Liming Liu, Raymond Joseph Moniz, Jason Laskey, SuChun Hsieh, Mike Lee, Jin-Hwan Han, Hassan Issafras, Sarah Javaid, Andrey Loboda, Svetlana Sadekova, Joann A. O'Connor, Archie Tse, Juha Punnonen

Published Oct 2, 2018 · Vol. 9, No. 77 · pp. 34459-34470

Inactive immune pathways in triple negative breast cancers that showed resistance to neoadjuvant chemotherapy as inferred from kinase activity profiles Research Paper

Takeshi Sawada, Riet Hilhorst, Savithri Rangarajan, Masayuki Yoshida, Yuko Tanabe, Kenji Tamura, Takayuki Kinoshita, Tatsu Shimoyama, Rinie van Beuningen, Rob Ruijtenbeek, Hitoshi Tsuda, Fumiaki Koizumi

Published Sep 28, 2018 · Vol. 9, No. 76 · pp. 34229-34239

Enhanced expression of PD-L1 in non-muscle-invasive bladder cancer after treatment with Bacillus Calmette-Guerin Research Paper

Akihito Hashizume, Susumu Umemoto, Tomoyuki Yokose, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Kahori Shoji, Satoshi Wada, Yohei Miyagi, Takeshi Kishida, Tetsuro Sasada

Published Sep 25, 2018 · Vol. 9, No. 75 · pp. 34066-34078

In tumor cells, thyroid hormone analogues non-immunologically regulate PD-L1 and PD-1 accumulation that is anti-apoptotic Research Perspective

Hung-Yun Lin, Yu-Tang Chin, Ya-Jung Shih, Yi-Ru Chen, Matthew Leinung, Kelly A. Keating, Shaker A. Mousa, Paul J. Davis

Published Sep 25, 2018 · Vol. 9, No. 75 · pp. 34033-34037

Immune-related adverse events and atypical radiological response with checkpoint inhibitor immunotherapy in an elderly patient with high PD-L1 expressing lung adenocarcinoma Case Report

Eduard Teixidor, Elia Sais, Carmen Amalia VÃ¡squez, Walter Carbajal, Alejandro HernÃ¡ndez, Gloria SÃ¡nchez, Angel Izquierdo, Sara Verdura, Javier A. MenÃ©ndez, Joaquim Bosch-Barrera

Published Aug 31, 2018 · Vol. 9, No. 68 · pp. 33043-33049

Selecting suitable chemotherapies for PD-1/PD-L1 blockade to optimize the tumor immune microenvironment News

Shohei Koyama, Izumi Nagatomo, Takashi Kijima, Atsushi Kumanogoh

Published Aug 18, 2018 · Vol. 9, No. 66 · pp. 32552-32553

Topoisomerase I inhibitor, irinotecan, depletes regulatory T cells and up-regulates MHC class I and PD-L1 expression, resulting in a supra-additive antitumor effect when combined with anti-PD-L1 antibodies Research Paper

Toshiki Iwai, Masamichi Sugimoto, Daiko Wakita, Keigo Yorozu, Mitsue Kurasawa, Kaname Yamamoto

Published Jul 31, 2018 · Vol. 9, No. 59 · pp. 31411-31421

Intratumoral immune-biomarkers and mismatch repair status in leiyomyosarcoma -potential predictive markers for adjuvant treatment: a pilot study Research Paper

Jonathan E. Cohen, Feras Eleyan, Aviad Zick, Tamar Peretz, Daniela Katz

Published Jul 20, 2018 · Vol. 9, No. 56 · pp. 30847-30854

PD-L1 expression comparison between primary and relapsed non-small cell lung carcinoma using whole sections and clone SP263 Research Paper

Enrico Munari, Giuseppe Zamboni, Gianluigi Lunardi, Marcella Marconi, Marco Sommaggio, Matteo Brunelli, Guido Martignoni, George J. Netto, Mohammad O. Hoque, Francesca Moretta, Maria Cristina Mingari, Maria Cristina Pegoraro, Francesca Romana Mariotti, Paola Vacca, Lorenzo Moretta, Giuseppe Bogina

Published Jul 13, 2018 · Vol. 9, No. 54 · pp. 30465-30471

Real world experience in low-dose ipilimumab in combination with PD-1 blockade in advanced melanoma patients Research Paper

Michael Constantin Kirchberger, Alvaro Moreira, Michael Erdmann, Gerold Schuler, Lucie Heinzerling

Published Jun 22, 2018 · Vol. 9, No. 48 · pp. 28903-28909

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Carbon ion irradiation enhances the antitumor efficacy of dual immune checkpoint blockade therapy both for local and distant sites in murine osteosarcoma Research Paper

Increased PD-L1 expression in radioresistant HNSCC cell lines after irradiation affects cell proliferation due to inactivation of GSK-3beta Research Paper

Programmed death ligand 1 expression in early stage, resectable non-small cell lung cancer Research Paper

Genomic characterization of metastatic ultra-hypermutated interdigitating dendritic cell sarcoma through rapid research autopsy Research Paper

Clinical characteristics, treatment outcomes and potential novel therapeutic options for patients with neuroendocrine carcinoma of the prostate Research Paper

Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer Research Paper

STAT1 deficiency supports PD-1/PD-L1 signaling resulting in dysfunctional TNFÎ± mediated immune responses in a model of NSCLC Research Paper

Correction: PD-L1 expression heterogeneity in non-small cell lung cancer: evaluation of small biopsies reliability Correction

CD39⁺ regulatory T cells accumulate in colon adenocarcinomas and display markers of increased suppressive function Research Paper

Anti-PD-1 therapy for clinical treatment of lymphoma: a single-arm meta-analysis Meta-Analysis

Characterization of murine CEACAM1 in vivo reveals low expression on CD8⁺ T cells and no tumor growth modulating activity by anti-CEACAM1 mAb CC1 Research Paper

Inactive immune pathways in triple negative breast cancers that showed resistance to neoadjuvant chemotherapy as inferred from kinase activity profiles Research Paper

Enhanced expression of PD-L1 in non-muscle-invasive bladder cancer after treatment with Bacillus Calmette-Guerin Research Paper

In tumor cells, thyroid hormone analogues non-immunologically regulate PD-L1 and PD-1 accumulation that is anti-apoptotic Research Perspective

Immune-related adverse events and atypical radiological response with checkpoint inhibitor immunotherapy in an elderly patient with high PD-L1 expressing lung adenocarcinoma Case Report

Selecting suitable chemotherapies for PD-1/PD-L1 blockade to optimize the tumor immune microenvironment News

Topoisomerase I inhibitor, irinotecan, depletes regulatory T cells and up-regulates MHC class I and PD-L1 expression, resulting in a supra-additive antitumor effect when combined with anti-PD-L1 antibodies Research Paper

Intratumoral immune-biomarkers and mismatch repair status in leiyomyosarcoma -potential predictive markers for adjuvant treatment: a pilot study Research Paper

PD-L1 expression comparison between primary and relapsed non-small cell lung carcinoma using whole sections and clone SP263 Research Paper

Real world experience in low-dose ipilimumab in combination with PD-1 blockade in advanced melanoma patients Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Carbon ion irradiation enhances the antitumor efficacy of dual immune checkpoint blockade therapy both for local and distant sites in murine osteosarcoma Research Paper

Increased PD-L1 expression in radioresistant HNSCC cell lines after irradiation affects cell proliferation due to inactivation of GSK-3beta Research Paper

Programmed death ligand 1 expression in early stage, resectable non-small cell lung cancer Research Paper

Genomic characterization of metastatic ultra-hypermutated interdigitating dendritic cell sarcoma through rapid research autopsy Research Paper

Clinical characteristics, treatment outcomes and potential novel therapeutic options for patients with neuroendocrine carcinoma of the prostate Research Paper

Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer Research Paper

STAT1 deficiency supports PD-1/PD-L1 signaling resulting in dysfunctional TNFÎ± mediated immune responses in a model of NSCLC Research Paper

Correction: PD-L1 expression heterogeneity in non-small cell lung cancer: evaluation of small biopsies reliability Correction

CD39+ regulatory T cells accumulate in colon adenocarcinomas and display markers of increased suppressive function Research Paper

Anti-PD-1 therapy for clinical treatment of lymphoma: a single-arm meta-analysis Meta-Analysis

Characterization of murine CEACAM1 in vivo reveals low expression on CD8+ T cells and no tumor growth modulating activity by anti-CEACAM1 mAb CC1 Research Paper

Inactive immune pathways in triple negative breast cancers that showed resistance to neoadjuvant chemotherapy as inferred from kinase activity profiles Research Paper

Enhanced expression of PD-L1 in non-muscle-invasive bladder cancer after treatment with Bacillus Calmette-Guerin Research Paper

In tumor cells, thyroid hormone analogues non-immunologically regulate PD-L1 and PD-1 accumulation that is anti-apoptotic Research Perspective

Immune-related adverse events and atypical radiological response with checkpoint inhibitor immunotherapy in an elderly patient with high PD-L1 expressing lung adenocarcinoma Case Report

Selecting suitable chemotherapies for PD-1/PD-L1 blockade to optimize the tumor immune microenvironment News

Topoisomerase I inhibitor, irinotecan, depletes regulatory T cells and up-regulates MHC class I and PD-L1 expression, resulting in a supra-additive antitumor effect when combined with anti-PD-L1 antibodies Research Paper

Intratumoral immune-biomarkers and mismatch repair status in leiyomyosarcoma -potential predictive markers for adjuvant treatment: a pilot study Research Paper

PD-L1 expression comparison between primary and relapsed non-small cell lung carcinoma using whole sections and clone SP263 Research Paper

Real world experience in low-dose ipilimumab in combination with PD-1 blockade in advanced melanoma patients Research Paper

CD39⁺ regulatory T cells accumulate in colon adenocarcinomas and display markers of increased suppressive function Research Paper

Characterization of murine CEACAM1 in vivo reveals low expression on CD8⁺ T cells and no tumor growth modulating activity by anti-CEACAM1 mAb CC1 Research Paper