The Oncosearch | Oncotarget

What is the role of checkpoint inhibitors in neuroendocrine neoplasms? Editorial

Taymeyah Al-Toubah, Eleonora Pelle, Jonathan Strosberg

Published Oct 4, 2020 · Vol. 11, No. 42 · pp. 3751-3752

Keywords: neuroendocrine neoplasm, neuroendocrine tumor, neuroendocrine carcinoma, immunotherapy, PD-1 inhibitor

Combination of copanlisib with cetuximab improves tumor response in cetuximab-resistant patient-derived xenografts of head and neck cancer Research Paper

Konrad Klinghammer, Oliver Politz, Theresa Eder, Raik Otto, Jan-Dirk Raguse, Andreas Albers, Andreas Kaufmann, Ingeborg Tinhofer, Jens Hoffmann, Ulrich Keller, Ulrich Keilholz

Published Oct 1, 2020 · Vol. 11, No. 41 · pp. 3688-3697

Keywords: cetuximab, copanlisib, head and neck squamous cell carcinoma, HPV, patient-derived xenograft model

PD-1/PD-L1 expression in anal squamous intraepithelial lesions Research Paper

Margot Bucau, Nathalie Gault, Nanthara Sritharan, Emy Valette, Charlotte Charpentier, Francine Walker, Anne Couvelard, Laurent Abramowitz

Published Sep 17, 2020 · Vol. 11, No. 39 · pp. 3582-3589

Keywords: anal dysplasia, PD-L1, HPV, anal cancer, immune microenvironment

A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo Research Paper

Tiziano Ongaro, Baptiste Gouyou, Marco Stringhini, Riccardo Corbellari, Dario Neri, Alessandra Villa

Published Aug 23, 2020 · Vol. 11, No. 41 · pp. 3698-3711

Keywords: tumor targeting, fibronectin, immunocytokines, interleukin-2, protein engineering

Differentially expressed full-length, fusion and novel isoforms transcripts-based signature of well-differentiated keratinized oral squamous cell carcinoma Research Paper

Neetu Singh, Dinesh Kumar Sahu, Ratnesh Kumar Tripathi, Archana Mishra, Hari Shyam, Pratap Shankar, Mayank Jain, Nawazish Alam, Anil Kumar, Abhishek Mishra, Rebecca Chowdhry, Anjana Singh, Sameer Gupta, Divya Mehrotra, Preeti Agarwal, Madhu Mati Goel, Arun Chaturvedi, Satya Prakash Agarwal, Manish Bajpai, Devendra Kumar Gupta, Madan Lal Brahma Bhatt, Ravi Kant

Published Jul 22, 2020 · Vol. 11, No. 34 · pp. 3227-3243

Keywords: oral tongue squamous cell carcinoma, microarray, transcriptomics, integrative bioinformatics, differentially expressed gene

Molecular profiling of melanoma brain metastases compared to primary cutaneous melanoma and to extracranial metastases Research Paper

Gino K. In, Kelsey Poorman, Michelle Saul, Steven O’Day, Jeffrey M. Farma, Anthony J. Olszanski, Michael S. Gordon, Jacob S. Thomas, Burton Eisenberg, Lawrence Flaherty, Amy Weise, Steven Daveluy, Geoffrey Gibney, Michael B. Atkins, Ari Vanderwalde

Published Jul 16, 2020 · Vol. 11, No. 33 · pp. 3118-3128

Keywords: melanoma, brain metastases, BRAF, PD-L1, TMB

Rapid onset type 1 diabetes with anti-PD-1 directed therapy Research Paper

Karen Yun, Gregory Daniels, Kathryn Gold, Karen Mccowen, Sandip Pravin Patel

Published Jun 23, 2020 · Vol. 11, No. 28 · pp. 2740-2746

Keywords: type 1 diabetes, diabetic ketoacidosis (DKA), immune-related adverse event (irAE), immunotherapy, PD-1 inhibitors

Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer Research Paper

Anders Handrup Kverneland, Magnus Pedersen, Marie Christine Wulff Westergaard, Morten Nielsen, Troels Holz Borch, Lars Rønn Olsen, Gitte Aasbjerg, Saskia J. Santegoets, Sjoerd H. van der Burg, Katy Milne, Brad H. Nelson, Özcan Met, Marco Donia, Inge Marie Svane

Published May 6, 2020 · Vol. 11, No. 22 · pp. 2092-2105

Keywords: adoptive cell therapy, tumor-infiltrating lymphocytes, ovarian cancer, combinational immune therapy, checkpoint inihibors

Lymph nodes may be a source for immunetherapy in gastric cancer Research Paper

Paula Baraúna Assumpção, Erika Couto Canelas, Aline Cruz Ramos, Ana Anaissi, João Felipe Acioli, Geraldo Ishak, Sidney Santos, Samia Demachki, Paulo Assumpção

Published Apr 21, 2020 · Vol. 11, No. 19 · pp. 1729-1736

Keywords: gastric cancer, immunotherapy, lymph nodes

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

Andy Karabajakian, Thibaut Garrivier, Carole Crozes, Nicolas Gadot, Jean-Yves Blay, Frédéric Bérard, Philippe Céruse, Philippe Zrounba, Pierre Saintigny, Charles Mastier, Jérôme Fayette

Published Apr 11, 2020 · Vol. 11, No. 18 · pp. 1618-1628

Keywords: squamous cell carcinoma of head and neck, immunotherapy, programmed cell death 1 receptor, kinetics

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Matthew H. Taylor, Ajjai S. Alva, Timothy Larson, Sebastian Szpakowski, Das Purkaystha, Alpesh Amin, Linda Karpiak, Sarina A. Piha-Paul

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1235-1243

Keywords: advanced malignancies, basket trial, dovitinib, histology-agnostic, mutation-specific

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

John M. Idso, Shunhua Lao, Nathan J. Schloemer, Jeffrey Knipstein, Robert Burns, Monica S. Thakar, Subramaniam Malarkannan

Published Mar 25, 2020 · Vol. 11, No. 20 · pp. 1799-1815

Keywords: NK cells, histone deacetylase inhibitor, Ewing sarcoma, rhabdomyosarcoma, immunotherapy

Recurrent metastatic clear cell renal carcinoma with sarcomatoid dedifferentiation treated with surgery and Cabozantinib Case Report

Johnny Boustany, Maher Abdessater, Charbel El Hachem, Ziad El Khoury, Walid El Khoury, Raghid El Khoury

Published Mar 24, 2020 · Vol. 11, No. 20 · pp. 1922-1928

Keywords: clear cell renal carcinoma, sarcomatoid dedifferentiation, metastasectomy, cabozantinib

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

Ryan P. Gilley, Peter H. Dube

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 740-754

Keywords: cancer immunotherapy, cancer vaccination, checkpoint blockade, melanoma, listeria

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Pierre Boyé, Franck Floch, François Serres, Zacharie Segaoula, Juliette Hordeaux, Quentin Pascal, Virginie Coste, Sandy Courapied, Emmanuel Bouchaert, Agata Rybicka, Claire Mazuy, Laurent Marescaux, Kévyn Geeraert, Corinne Fournel-Fleury, Alain Duhamel, François Machuron, Pierre Ferré, Aurélie Pétain, Nicolas Guilbaud, Dominique Tierny, Bruno Gomes

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 671-686

Keywords: etoposide phosphate, F14512, non-Hodgkin lymphoma, pet dog model, P-glycoprotein

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Richard K. Yang, Yun Qing, Fatima Zahra Jelloul, Mark J. Routbort, Peng Wang, Kenna Shaw, Jiexin Zhang, Jack Lee, L. Jeffrey Medeiros, Scott Kopetz, Michael T. Tetzlaff, Russell R. Broaddus

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 600-618

Keywords: biomarkers, immunotherapy, mutations, TMB, histology

Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson’s disease Research Paper

Rizwanul Haque, Shamsuzzama, Lalit Kumar, Tanuj Sharma, Soobiya Fatima, Pooja Jadiya, Mohammad I. Siddiqi, Aamir Nazir

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 634-649

Keywords: Parkinson’s, human insulin, aggregation, Daf-2, Caenorhabditis elegans (C. elegans)

Exercise reduces immune suppression and breast cancer progression in a preclinical model Research Paper

Erik Wennerberg, Claire Lhuillier, Marissa D. Rybstein, Kyle Dannenberg, Nils-Petter Rudqvist, Graeme J. Koelwyn, Lee W. Jones, Sandra Demaria

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 452-461

Keywords: breast cancer, exercise training, immune cells, immunotherapy, myeloid-derived suppressor cells

Cetuximab is efficient and safe in patients with advanced cutaneous squamous cell carcinoma: a retrospective, multicentre study Research Paper

Henri Montaudié, Julien Viotti, Patrick Combemale, Caroline Dutriaux, Nicolas Dupin, Caroline Robert, Laurent Mortier, Régis Kaphan, Anne-Bénédicte Duval-Modeste, Stéphane Dalle, Julie De Quatrebarbes, Andrea Stefan, Florence Brunet-Possenti, Maria Kogay, Alexandra Picard-Gauci, Gilles Poissonnet, Frédéric Peyrade

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 378-385

Keywords: cutaneous squamous cell carcinoma, cetuximab, epidermal growth factor receptor

Stratifying the stratifiers of triple negative breast cancer Editorial

Dong-Yu Wang, Zhe Jiang, Eldad Zacksenhaus

Published Jan 18, 2020 · Vol. 11, No. 4 · pp. 306-308

Keywords: triple negative breast cancer, molecular stratification, prognostication, microRNA, immunomodulation

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What is the role of checkpoint inhibitors in neuroendocrine neoplasms? Editorial

Combination of copanlisib with cetuximab improves tumor response in cetuximab-resistant patient-derived xenografts of head and neck cancer Research Paper

PD-1/PD-L1 expression in anal squamous intraepithelial lesions Research Paper

A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo Research Paper

Differentially expressed full-length, fusion and novel isoforms transcripts-based signature of well-differentiated keratinized oral squamous cell carcinoma Research Paper

Molecular profiling of melanoma brain metastases compared to primary cutaneous melanoma and to extracranial metastases Research Paper

Rapid onset type 1 diabetes with anti-PD-1 directed therapy Research Paper

Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer Research Paper

Lymph nodes may be a source for immunetherapy in gastric cancer Research Paper

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

Recurrent metastatic clear cell renal carcinoma with sarcomatoid dedifferentiation treated with surgery and Cabozantinib Case Report

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson’s disease Research Paper

Exercise reduces immune suppression and breast cancer progression in a preclinical model Research Paper

Cetuximab is efficient and safe in patients with advanced cutaneous squamous cell carcinoma: a retrospective, multicentre study Research Paper

Stratifying the stratifiers of triple negative breast cancer Editorial

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

What is the role of checkpoint inhibitors in neuroendocrine neoplasms? Editorial

Combination of copanlisib with cetuximab improves tumor response in cetuximab-resistant patient-derived xenografts of head and neck cancer Research Paper

PD-1/PD-L1 expression in anal squamous intraepithelial lesions Research Paper

A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo Research Paper

Differentially expressed full-length, fusion and novel isoforms transcripts-based signature of well-differentiated keratinized oral squamous cell carcinoma Research Paper

Molecular profiling of melanoma brain metastases compared to primary cutaneous melanoma and to extracranial metastases Research Paper

Rapid onset type 1 diabetes with anti-PD-1 directed therapy Research Paper

Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer Research Paper

Lymph nodes may be a source for immunetherapy in gastric cancer Research Paper

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

Recurrent metastatic clear cell renal carcinoma with sarcomatoid dedifferentiation treated with surgery and Cabozantinib Case Report

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson’s disease Research Paper

Exercise reduces immune suppression and breast cancer progression in a preclinical model Research Paper

Cetuximab is efficient and safe in patients with advanced cutaneous squamous cell carcinoma: a retrospective, multicentre study Research Paper

Stratifying the stratifiers of triple negative breast cancer Editorial