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Association of the EGF-TM7 receptor CD97 expression with FLT3-ITD in acute myeloid leukemia Research Paper

Manja Wobus, Martin BornhÃ¤user, Angela Jacobi, Martin KrÃ¤ter, Oliver Otto, Claudia Ortlepp, Jochen Guck, Gerhard Ehninger, Christian Thiede, Uta OelschlÃ¤gel

Published Oct 7, 2015 · Vol. 6, No. 36 · pp. 38804-38815

T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia Research Paper

Houda Alachkar, Martin Mutonga, Gregory Malnassy, Jae-Hyun Park, Noreen Fulton, Alex Woods, Liping Meng, Justin Kline, Gordana Raca, Olatoyosi Odenike, Naofumi Takamatsu, Takashi Miyamoto, Yo Matsuo, Wendy Stock, Yusuke Nakamura

Published Oct 2, 2015 · Vol. 6, No. 32 · pp. 33410-33425

High frequency of additional gene mutations in acute myeloid leukemia with MLL partial tandem duplication: DNMT3A mutation is associated with poor prognosis Research Paper

Hsiao-Wen Kao, Der-Cherng Liang, Ming-Chung Kuo, Jin-Hou Wu, Po Dunn, Po-Nan Wang, Tung-Liang Lin, Yu-Shu Shih, Sung-Tzu Liang, Tung-Huei Lin, Chen-Yu Lai, Chun-Hui Lin, Lee-Yung Shih

Published Sep 8, 2015 · Vol. 6, No. 32 · pp. 33217-33225

Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients Research Paper

Elisa Zuffa, Eugenia Franchini, Cristina Papayannidis, Carmen Baldazzi, Giorgia Simonetti, Nicoletta Testoni, Maria Chiara Abbenante, Stefania Paolini, Chiara Sartor, Sarah Parisi, Giovanni Marconi, Federica Cattina, Maria Teresa Bochicchio, Claudia Venturi, Emanuela Ottaviani, Michele Cavo, Giovanni Martinelli

Published Sep 5, 2015 · Vol. 6, No. 31 · pp. 31284-31294

Clinical impact of CD200 expression in patients with acute myeloid leukemia and correlation with other molecular prognostic factors Research Paper

Daniela Damiani, Mario Tiribelli, Donatella Raspadori, Santina Sirianni, Alessia Meneghel, Margherita Cavalllin, Angela Michelutti, Eleonora Toffoletti, Antonella Geromin, Erica Simeone, Monica Bocchia, Renato Fanin

Published Aug 18, 2015 · Vol. 6, No. 30 · pp. 30212-30221

Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility Research Paper

Muhammad A Alvi, Darragh G McArt, Paul Kelly, Marc-Aurel Fuchs, Matthew Alderdice, Clare M McCabe, Victoria Bingham, Claire McGready, Shailesh Tripathi, Frank Emmert-Streib, Maurice B Loughrey, Stephen McQuaid, Perry Maxwell, Peter W Hamilton, Richard Turkington, Jacqueline A James, Richard H Wilson, Manuel Salto-Tellez

Published Jul 30, 2015 · Vol. 6, No. 25 · pp. 20863-20874

Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia Research Paper

Jean-Emmanuel Bibault, Martin Figeac, Nathalie HÃ©levaut, CÃ©line Rodriguez, Sabine Quief, ShÃ©hÃ©razade Sebda, Aline Renneville, Olivier Nibourel, Philippe Rousselot, BÃ©rengÃ¨re Gruson, HervÃ© Dombret, Sylvie Castaigne, Claude Preudhomme

Published Jun 2, 2015 · Vol. 6, No. 26 · pp. 22812-22821

BEX1 acts as a tumor suppressor in acute myeloid leukemia Research Paper

Oscar Lindblad, Tianfeng Li, Xianwei Su, Jianmin Sun, Nuzhat N. Kabir, Fredrik Levander, Hui Zhao, Gang Lu, Lars RÃ¶nnstrand, Julhash U. Kazi

Published May 26, 2015 · Vol. 6, No. 25 · pp. 21395-21405

Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy Research Paper

Wei An, Scott A. Nadeau, Bhopal C. Mohapatra, Dan Feng, Neha Zutshi, Matthew D. Storck, Priyanka Arya, James E. Talmadge, Jane L. Meza, Vimla Band, Hamid Band

Published Mar 19, 2015 · Vol. 6, No. 12 · pp. 10498-10509

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia Research Paper

Ayako Nogami, Gaku Oshikawa, Keigo Okada, Shusaku Fukutake, Yoshihiro Umezawa, Toshikage Nagao, Tetsuya Kurosu, Osamu Miura

Published Mar 16, 2015 · Vol. 6, No. 11 · pp. 9189-9205

Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasia-related changes Clinical Research Papers

Raynier Devillier, VÃ©ronique Mansat-De Mas, Veronique Gelsi-Boyer, Cecile Demur, Anne Murati, Jill Corre, Thomas Prebet, Sarah Bertoli, Mandy Brecqueville, Christine Arnoulet, Christian Recher, Norbert Vey, Marie-Joelle Mozziconacci, Eric Delabesse, Daniel Birnbaum

Published Feb 28, 2015 · Vol. 6, No. 10 · pp. 8388-8396

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia Research Paper

Alisa B. Lee-Sherick, Weihe Zhang, Kelly K. Menachof, Amanda A. Hill, Sean Rinella, Gregory Kirkpatrick, Lauren S. Page, Michael A. Stashko, Craig T. Jordan, Qi Wei, Jing Liu, Dehui Zhang, Deborah DeRyckere, Xiaodong Wang, Stephen Frye, H. Shelton Earp, Douglas K. Graham

Published Feb 10, 2015 · Vol. 6, No. 9 · pp. 6722-6736

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

Aline Renneville, Raouf Ben Abdelali, Sylvie Chevret, Olivier Nibourel, Meyling Cheok, Cecile Pautas, Remy Dulery, Thomas Boyer, Jean-Michel Cayuela, Sandrine Hayette, Emmanuel Raffoux, Hassan Farhat, Nicolas Boissel, Christine Terre, Herve Dombret, Sylvie Castaigne, Claude Preudhomme

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 916-932

Keywords: acute myeloid leukemia, SNP array lesions, gene mutations, gemtuzumab ozogamicin, prognosis

Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia Research Paper

Francesco Albano, Antonella Zagaria, Luisa Anelli, Paola Orsini, Crescenzio F Minervini, Luciana Impera, Paola Casieri, Nicoletta Coccaro, Giuseppina Tota, Claudia Brunetti, Angela Minervini, Domenico Pastore, Paola Carluccio, Anna Mestice, Angelo Cellamare, Giorgina Specchia

Published Dec 19, 2013 · Vol. 5, No. 3 · pp. 649-658

Keywords: acute promyelocytic leukemia, LEF1, prognosis, outcome

miR-150: targeting MLL leukemia Editorial

Xi Jiang, Jianjun Chen

Published Nov 14, 2012 · Vol. 3, No. 11 · pp. 1268-1269

Keywords: miR-150, MLL leukemia, FLT3, MYC, MYB, signaling, therapy

FLT3 in lineage specification and plasticity Research Perspective

Sarah Greenblatt, Donald Small

Published May 27, 2012 · Vol. 3, No. 5 · pp. 576-580

Keywords: FLT3, B220, leukemia, lineage, differentiation

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience. Research Paper

Olivier LaRochelle, Sarah Bertoli, FranÃ§ois Vergez, Jean Emmanuel Sarry, VÃ©ronique Mansat-De Mas, Sophie Dobbelstein, Nicole Dastugue, Anne-Claire Strzelecki, Cindy Cavelier, Laurent Creancier, Arnaud Pillon, Anna Kruczynski, Cecile Demur, Audrey Sarry, FranÃ§oise Huguet, Anne Huynh, Christian RÃ©cher, Eric Delabesse

Published Nov 9, 2011 · Vol. 2, No. 11 · pp. 850-861

Keywords: leukemia, DNMT3A, anthracyclins, idarubicin, AML

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Association of the EGF-TM7 receptor CD97 expression with FLT3-ITD in acute myeloid leukemia Research Paper

T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia Research Paper

High frequency of additional gene mutations in acute myeloid leukemia with MLL partial tandem duplication: DNMT3A mutation is associated with poor prognosis Research Paper

Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients Research Paper

Clinical impact of CD200 expression in patients with acute myeloid leukemia and correlation with other molecular prognostic factors Research Paper

Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility Research Paper

Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia Research Paper

BEX1 acts as a tumor suppressor in acute myeloid leukemia Research Paper

Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy Research Paper

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia Research Paper

Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasia-related changes Clinical Research Papers

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia Research Paper

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia Research Paper

miR-150: targeting MLL leukemia Editorial

FLT3 in lineage specification and plasticity Research Perspective

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience. Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Association of the EGF-TM7 receptor CD97 expression with FLT3-ITD in acute myeloid leukemia Research Paper

T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia Research Paper

High frequency of additional gene mutations in acute myeloid leukemia with MLL partial tandem duplication: DNMT3A mutation is associated with poor prognosis Research Paper

Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients Research Paper

Clinical impact of CD200 expression in patients with acute myeloid leukemia and correlation with other molecular prognostic factors Research Paper

Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility Research Paper

Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia Research Paper

BEX1 acts as a tumor suppressor in acute myeloid leukemia Research Paper

Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy Research Paper

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia Research Paper

Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasia-related changes Clinical Research Papers

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia Research Paper

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia Research Paper

miR-150: targeting MLL leukemia Editorial

FLT3 in lineage specification and plasticity Research Perspective

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience. Research Paper