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Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling Research Paper

Sausan A. Moharram, Rohit A. Chougule, Xianwei Su, Tianfeng Li, Jianmin Sun, Hui Zhao, Lars RÃ¶nnstrand, Julhash U. Kazi

Published Jul 21, 2016 · Vol. 7, No. 36 · pp. 57770-57782

Simultaneous inhibition of Vps34 kinase would enhance PI3KÎ´ inhibitor cytotoxicity in the B-cell malignancies Research Paper

Xiaochuan Liu, Aoli Wang, Xiaofei Liang, Juanjuan Liu, Fengming Zou, Cheng Chen, Zheng Zhao, Yuanxin Deng, Hong Wu, Ziping Qi, Beilei Wang, Li Wang, Feiyang Liu, Yunhe Xu, Wenchao Wang, Stacey M. Fernandes, Richard M. Stone, Ilene A. Galinsky, Jennifer R. Brown, Teckpeng Loh, James D. Griffin, Shanchun Zhang, Ellen L. Weisberg, Xin Zhang, Jing Liu, Qingsong Liu

Published Jul 18, 2016 · Vol. 7, No. 33 · pp. 53515-53525

FLT3 is implicated in cytarabine transport by human equilibrative nucleoside transporter 1 in pediatric acute leukemia Research Paper

Albert CatalÃ, MarÃ§al Pastor-Anglada, Liska Caviedes-CÃ¡rdenas, Roberta Malatesta, Susana Rives, Nerea Vega-GarcÃa, Mireia CamÃ³s, Paula FernÃ¡ndez-Calotti

Published Jul 6, 2016 · Vol. 7, No. 31 · pp. 49786-49799

Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations Research Paper

Sang-Yong Shin, Seung-Tae Lee, Hee-Jin Kim, Eun Hae Cho, Jong-Won Kim, Silvia Park, Chul Won Jung, Sun-Hee Kim

Published Jun 23, 2016 · Vol. 7, No. 34 · pp. 54825-54837

Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress Research Paper

Kshama A. Doshi, Rossana Trotta, Karthika Natarajan, Feyruz V. Rassool, Adriana E. Tron, Dennis Huszar, Danilo Perrotti, Maria R. Baer

Published Jun 21, 2016 · Vol. 7, No. 30 · pp. 48280-48295

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors Research Paper

Amanda M. Smith, Matthew D. Dun, Erwin M. Lee, Celeste Harrison, Richard Kahl, Hayley Flanagan, Nikita Panicker, Baratali Mashkani, Anthony S. Don, Jonathan Morris, Hamish Toop, Richard B. Lock, Jason A. Powell, Daniel Thomas, Mark A. Guthridge, Andrew Moore, Leonie K. Ashman, Kathryn A. Skelding, Anoop Enjeti, Nicole M. Verrills

Published Jun 18, 2016 · Vol. 7, No. 30 · pp. 47465-47478

Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells Research Paper

Fangli Chen, Yuichi Ishikawa, Akimi Akashi, Tomoki Naoe, Hitoshi Kiyoi

Published Jun 17, 2016 · Vol. 7, No. 30 · pp. 47018-47032

An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia Research Paper

Sophie Lopez, Edwige Voisset, Julie C. Tisserand, Cyndie Mosca, Thomas Prebet, David Santamaria, Patrice Dubreuil, Paulo De Sepulveda

Published Jun 13, 2016 · Vol. 7, No. 32 · pp. 51163-51173

Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity Research Paper

Hai Yi, Dongfeng Zeng, Zhaohua Shen, Jun Liao, Xiaoguo Wang, Yao Liu, Xi Zhang, Peiyan Kong

Published May 26, 2016 · Vol. 7, No. 26 · pp. 40387-40397

Dual inhibition of AKT/FLT3-ITD by A674563 overcomes FLT3 ligand-induced drug resistance in FLT3-ITD positive AML Research Paper

Aoli Wang, Hong Wu, Cheng Chen, Chen Hu, Ziping Qi, Wenchao Wang, Kailin Yu, Xiaochuan Liu, Fengming Zou, Zheng Zhao, Jiaxin Wu, Juan Liu, Feiyang Liu, Li Wang, Richard M. Stone, Ilene A. Galinksy, James D. Griffin, Shanchun Zhang, Ellen L. Weisberg, Jing Liu, Qingsong Liu

Published Apr 11, 2016 · Vol. 7, No. 20 · pp. 29131-29142

Expression of GADS enhances FLT3-induced mitogenic signaling Research Paper

Rohit A. Chougule, Eugenia Cordero, Sausan A. Moharram, Kristian Pietras, Lars RÃ¶nnstrand, Julhash U. Kazi

Published Feb 15, 2016 · Vol. 7, No. 12 · pp. 14112-14124

Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes Research Paper

Monica Messina, Sabina Chiaretti, Jiguang Wang, Anna Lucia Fedullo, Nadia Peragine, Valentina Gianfelici, Alfonso Piciocchi, Fulvia Brugnoletti, Filomena Di Giacomo, Simona Pauselli, Antony B. Holmes, Maria Cristina Puzzolo, Giulia Ceglie, Valerio Apicella, Marco Mancini, Geertruy te Kronnie, Anna Maria Testi, Antonella Vitale, Marco Vignetti, Anna Guarini, Raul Rabadan, Robin FoÃ

Published Feb 12, 2016 · Vol. 7, No. 12 · pp. 13886-13901

FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia Research Paper

Rohit A. Chougule, Julhash U. Kazi, Lars RÃ¶nnstrand

Published Feb 2, 2016 · Vol. 7, No. 9 · pp. 9964-9974

Mutational spectrum and risk stratification of intermediate-risk acute myeloid leukemia patients based on next-generation sequencing Research Paper

Bianhong Wang, Yangyang Liu, Guangyuan Hou, Lili Wang, Na Lv, Yuanyuan Xu, Yihan Xu, Xiuli Wang, Zhaoling Xuan, Yu Jing, Honghua Li, Xiangshu Jin, Ailing Deng, Li Wang, Xiaoning Gao, Liping Dou, Junbin Liang, Chongjian Chen, Yonghui Li, Li Yu

Published Jan 27, 2016 · Vol. 7, No. 22 · pp. 32065-32078

Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites Research Paper

Byungho Lim, Chan Kim, Jeong-Hwan Kim, Woo Sun Kwon, Won Seok Lee, Jeong Min Kim, Jun Yong Park, Hyo Song Kim, Kyu Hyun Park, Tae Soo Kim, Jong-Lyul Park, Hyun Cheol Chung, Sun Young Rha, Seon-Young Kim

Published Jan 22, 2016 · Vol. 7, No. 7 · pp. 8055-8066

Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia Research Paper

Setareh Safavi, Linda Olsson, Andrea Biloglav, Srinivas Veerla, Molly Blendberg, Johnbosco Tayebwa, Mikael Behrendtz, Anders Castor, Markus Hansson, Bertil Johansson, Kajsa Paulsson

Published Oct 30, 2015 · Vol. 6, No. 40 · pp. 42793-42802

CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia Research Paper

Sarah Bertoli, Helena Boutzen, Laure David, ClÃ©ment Larrue, FranÃ§ois Vergez, Anne Fernandez-Vidal, Lingli Yuan, Marie-Anne Hospital, JÃ©rÃ´me Tamburini, CÃ©cile Demur, Eric Delabesse, Estelle Saland, Jean-Emmanuel Sarry, Marie-Odile Galcera, VÃ©ronique Mansat-De Mas, Christine Didier, Christine Dozier, Christian RÃ©cher, StÃ©phane Manenti

Published Oct 16, 2015 · Vol. 6, No. 35 · pp. 38061-38078

IDH1/2 but not DNMT3A mutations are suitable targets for minimal residual disease monitoring in acute myeloid leukemia patients: a study by the Acute Leukemia French Association Clinical Research Papers

Houria Debarri, Delphine Lebon, Christophe Roumier, Meyling Cheok, Alice Marceau-Renaut, Olivier Nibourel, Sandrine Geffroy, Nathalie Helevaut, Philippe Rousselot, BÃ©rengÃ¨re Gruson, Claude Gardin, Marie-Lorraine Chretien, ShÃ©hÃ©razade Sebda, Martin Figeac, CÃ©line Berthon, Bruno Quesnel, Nicolas Boissel, Sylvie Castaigne, HervÃ© Dombret, Aline Renneville, Claude Preudhomme

Published Oct 12, 2015 · Vol. 6, No. 39 · pp. 42345-42353

CD40 controls CXCR5-induced recruitment of myeloid-derived suppressor cells to gastric cancer Research Paper

Yixin Ding, Jin Shen, Guangbo Zhang, Xiaojuan Chen, JiaMing Wu, Weichang Chen

Published Oct 9, 2015 · Vol. 6, No. 36 · pp. 38901-38911

Phase II clinical and exploratory biomarker study of dacomitinib in recurrent and/or metastatic esophageal squamous cell carcinoma Clinical Research Papers

Hyo Song Kim, Sung-Moo Kim, Hyunki Kim, Kyoung-Ho Pyo, Jong-Mu Sun, Myung-Ju Ahn, Keunchil Park, Bhumsuk Keam, Nak-Jung Kwon, Hwan Jung Yun, Hoon-Gu Kim, Ik-Joo Chung, Jong Seok Lee, Kyung Hee Lee, Dae Joon Kim, Changâ€‘Geol Lee, Jin Hur, Hyunsoo Chung, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Hye Ryun Kim, Yong Wha Moon, Yong Chan Lee, Joo Hang Kim, Soonmyung Paik, Byoung Chul Cho

Published Oct 9, 2015 · Vol. 6, No. 42 · pp. 44971-44984

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Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling Research Paper

Simultaneous inhibition of Vps34 kinase would enhance PI3KÎ´ inhibitor cytotoxicity in the B-cell malignancies Research Paper

FLT3 is implicated in cytarabine transport by human equilibrative nucleoside transporter 1 in pediatric acute leukemia Research Paper

Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations Research Paper

Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress Research Paper

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors Research Paper

Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells Research Paper

An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia Research Paper

Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity Research Paper

Dual inhibition of AKT/FLT3-ITD by A674563 overcomes FLT3 ligand-induced drug resistance in FLT3-ITD positive AML Research Paper

Expression of GADS enhances FLT3-induced mitogenic signaling Research Paper

Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes Research Paper

FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia Research Paper

Mutational spectrum and risk stratification of intermediate-risk acute myeloid leukemia patients based on next-generation sequencing Research Paper

Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites Research Paper

Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia Research Paper

CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia Research Paper

IDH1/2 but not DNMT3A mutations are suitable targets for minimal residual disease monitoring in acute myeloid leukemia patients: a study by the Acute Leukemia French Association Clinical Research Papers

CD40 controls CXCR5-induced recruitment of myeloid-derived suppressor cells to gastric cancer Research Paper

Phase II clinical and exploratory biomarker study of dacomitinib in recurrent and/or metastatic esophageal squamous cell carcinoma Clinical Research Papers

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling Research Paper

Simultaneous inhibition of Vps34 kinase would enhance PI3KÎ´ inhibitor cytotoxicity in the B-cell malignancies Research Paper

FLT3 is implicated in cytarabine transport by human equilibrative nucleoside transporter 1 in pediatric acute leukemia Research Paper

Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations Research Paper

Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress Research Paper

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors Research Paper

Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells Research Paper

An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia Research Paper

Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity Research Paper

Dual inhibition of AKT/FLT3-ITD by A674563 overcomes FLT3 ligand-induced drug resistance in FLT3-ITD positive AML Research Paper

Expression of GADS enhances FLT3-induced mitogenic signaling Research Paper

Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes Research Paper

FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia Research Paper

Mutational spectrum and risk stratification of intermediate-risk acute myeloid leukemia patients based on next-generation sequencing Research Paper

Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites Research Paper

Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia Research Paper

CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia Research Paper

IDH1/2 but not DNMT3A mutations are suitable targets for minimal residual disease monitoring in acute myeloid leukemia patients: a study by the Acute Leukemia French Association Clinical Research Papers

CD40 controls CXCR5-induced recruitment of myeloid-derived suppressor cells to gastric cancer Research Paper

Phase II clinical and exploratory biomarker study of dacomitinib in recurrent and/or metastatic esophageal squamous cell carcinoma Clinical Research Papers